Institute of Psychology,Chinese Academy Of Sciences
Not a member yet
6627 research outputs found
Sort by
HIPPOCAMPAL SUBFIELD VOLUMES IN PATIENTS WITH SCHIZOPHRENIA AND THEIR UNAFFECTED FIRST-DEGREE RELATIVES
No full text
Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats
No full textDiabetic retinopathy is severe damage to the retina caused by complications of diabetes, and is the prevailing cause of blindness. Accumulating evidence from both animal models and humans suggests that the inflammatory process plays a key role in the development of diabetic retinopathy and is facilitated by innate immune response. The aim of this study was to examine whether the TLR4 signaling pathway was involved in the streptozotocin-induced diabetic rat retina
Sex-related difference in food-anticipatory activity of mice
No full textThe expression of food-anticipatory activity (FAA) is induced by restricted feeding (RF), and its entrainment requires food-entrainable oscillators, the neuroanatomical basis of which is currently unclear. Although RF impacts various hormones, sex-related differences in FAA are unclear. 'Here, we report significantly more food-anticipatory wheel-running activity in male than in female mice during RF. In parallel with the sex-related difference in FAA, male and female mice display different food intake and body weight in response to RF. Since gonadal hormones could be involved in the sex-specific difference in FAA, we compared sham and gonadectomized male and female wild-type mice. In gonadectomized mice, the sex difference in FAA was abolished, indicating a role for gonadal hormones in FAA. Further, plasma concentrations of the hormone ghrelin were higher in female than in male mice during ad libitum (AL) feeding, and RF induced a temporal advance in its peak in both sexes. RF also shifted the expression peak of the circadian gene mPer1 in the hippocampus and liver, although no sex difference was found in either the level or the cyclic phase of its expression. Per1(Brdm1) mutant mice were still sexually dimorphic for FAA, but diminished FAA was noted in both male and female Per2(Brdm1) mutant mice. In summary, our results imply that gonadal hormones contribute to the sex difference in FAA, possibly through modulating ghrelin activity. (C) 2015 Published by Elsevier Inc
SELF ADMINISTRATION OF OXYCODONE ALTERS SYNAPTIC PLASTICITY GENE EXPRESSION IN THE HIPPOCAMPUS DIFFERENTIALLY IN MALE ADOLESCENT AND ADULT MICE
No full textAbuse and addiction to prescription opioids such as oxycodone (a short-acting Mu opioid receptor (MOP-r) agonist) in adolescence is a pressing public health issue. We have previously shown differences in oxycodone self-administration behaviors between adolescent and adult C57BL/6J mice and expression of striatal neurotransmitter receptor genes, in areas involved in reward. In this study, we aimed to determine whether oxycodone self-administration differentially affects genes regulating synaptic plasticity in the hippocampus of adolescent compared to adult mice, since the hippocampus may be involved in learning aspects associated with chronic drug self administration. Hippocampus was isolated for mRNA analysis from mice that had self administered oxycodone (0.25 mg/kg/infusion) 2 h/day for 14 consecutive days or from yoked saline controls. Gene expression was analyzed with real-time polymerase chain reaction (PCR) using a commercially available “synaptic plasticity” PCR array containing 84 genes. We found that adolescent and adult control mice significantly differed in the expression of several genes in the absence of oxycodone exposure, including those coding for mitogen-activated protein kinase, calcium/calmodulin-dependent protein kinase II gamma subunit, glutamate receptor, ionotropic AMPA2 and metabotropic 5. Chronic oxycodone self administration increased proviral integration site 1 (Pim1) and thymoma viral proto-oncogene 1 mRNA levels compared to controls in both age groups. Both Pim1 and cadherin 2 mRNAs showed a significant combined effect of Drug Condition and Age × Drug Condition. Furthermore, the mRNA levels of both cadherin 2 and cAMP response element modulators showed an experiment-wise significant difference between oxycodone and saline control in adult but not in adolescent mice. Overall, this study demonstrates for the first time that chronic oxycodone self-administration differentially alters synaptic plasticity gene expression in the hippocampus of adolescent and adult mice.NIHDr. Miriam and Sheldon G. Adelson Medical Research Foundatio
ESI中心理学及相关领域热点论文信息推送2015年第4期（总第24期）
No full text
ESI中心理学及相关领域热点论文信息推送
——基于2015年7月更新数据
ESI（Essential Science Indicators）热点论文指近两年内发表的在近两个月内被引次数高居前千分之一的SCI/SSCI文章，即最近两个月内最受关注的文章。
本期入榜文章是2013年2月至2015年2月发表的文章中，在2015年3月和4月两个月内被引次数排名前千分之一的文章。数据更新时间为2015年7月9日。
本期ESI发布精神病学/心理学领域的热点文章75篇，其中首次入榜文章45篇。单篇最高被引112次，最低被引4次。被引112次的文章由伦敦大学学院（University College London）的Susan Michie DPhil等人发表在Annals of Behavioral Medicine上，标题为“The behavior change technique taxonomy (v1) of 93 hierarchically clustered techniques: building an international consensus for the reporting of behavior change interventions”，关于行为改变干预（behavior change intervention）中的行为改变技术（behavior change techniques，BCTs）的阶层式结构分类系统（hierarchically structured taxonomy）。首次入榜的45篇中单篇最高被引31次的文章是由密歇根大学的（University of Michigan）的Ethan Kross发表在PLOS ONE上，标题为“Facebook Use Predicts Declines in Subjective Well-Being in Young Adults”，阐述Facebook使用情况可预测主观幸福感的波动。
就研究主题而言，除心理统计、认知、疼痛、精神分裂症、抑郁、双相障碍、自闭症和注意缺陷多动障碍等长期入榜之外，另有首次入榜的文章值得关注，如：
1-31：健康行为研究中的两大计划干预技术——执行意向(implementation intention)和行动计划（action planning）；
1-34：关于帕金森病患者执行功能障碍的综述；
1-35：色彩心理学（Color Psychology）——色彩与人类心理功能之间的关系；
1-38：基于计算机的认知训练是否对注意、记忆以及执行功能有效？
1-39：从政治和心理学角度看政治意识形态（Political Ideology）；
1-41：土耳其机器人（Mechanical Turk，MTurk，亚马逊旗下的在线劳动力交易平台）已成为社会学家和心理学家开展调查和获取试验数据的来源；
1-45：DSM-5中人格与心理病理学的分类；
1-51：关于视觉词汇识别（visual word recognition）的综述；
1-54：从大五人格的3个不同视角研究亲密伴侣的人格特质与关系满意度；
1-57：关于脑活动的无尺度动力学（Scale-free brain activity）的综述；
1-67/68：加拿大国家轨道研究项目(National Trajectory Project) 对无刑事责任能力的心理障碍患者（not criminally responsible on account of mental disorder，NCRMD）展开调研。
该领域所有热点文章的详细信息请见附表1（按文章被引次数排列）。
本期发布神经科学与行为领域热点文章96篇，其中首次入榜文章52篇。单篇最高被引290次，最低被引3次。被引290次的文章由布里斯托大学（Bristol University ）的Marcus R. Munafò等人发表在Nature Reviews Neuroscience 上，标题为“Power failure: why small sample size undermines the reliability of neuroscience ”，讨论了小样本如何损害神经科学的信度。首次入榜的52篇中单篇最高被引61次的是北京师范大学的夏明睿等人发表在PLOS ONE上的工作，标题为“BrainNet Viewer: A Network Visualization Tool for Human Brain Connectomics”，介绍了一个名为“BrainNet Viewer“的脑网络绘制工具。
就研究主题而言，除肌萎缩性脊髓侧索硬化症、多发性硬化症、癫痫和疼痛等神经系统疾病、阿尔茨海默症等神经系统退行性病、神经系统发育、可塑性、学习记忆等长期入榜的主题之外，另有首次入榜的文章值得关注，如：
2-28：关于地中海饮食（Mediterranean diet）与中风、抑郁、认知受损和帕金森氏病关系的元分析；
2-49：从神经生物学和转化研究等角度对复吸（relapse）的恢复模型（reinstatement model）进行综述；
2-53：颞上回（superior temporal gyrus，STG）参与语音特征编码；
2-64：一项长达10年的研究证实了母亲对早产儿的袋鼠式护理（Kangaroo Care）可改善儿童的睡眠规律程度等生理指标及应激反应和执行功能等认知水平；
2-76：神经元低频（α）震荡和高频（γ）震荡是否标志猴子视觉皮层信息流的不同走向？
2-87：为脊髓严重受损的瘫痪大鼠植入电子硬脊膜（Electronic dura，一种在柔软度、拉伸能力和变形能力等方面与脊髓的外层保护膜硬脊膜十分接近的柔性器材），使其恢复行走能力；
2-92：内侧颞叶受损对基于奖赏的跨期选择（intertemporal choice）的影响；
2-96：综述：记忆相关的脑单侧优势（brain lateralisation）。
该领域所有热点文章的详细信息请见附表2（按文章被引次数排列）。
<br clear="all" /
Modulation of the brain activity in outcome evaluation by the presence of an audience: An electrophysiological investigation
No full textThe audience effect refers to the phenomenon that one's performance on a task is affected by the presence of others. Here we investigated how the audience effect modulates the neurocognitive signatures underlying people's evaluation of their own task performance/outcome. Participants in our study played a gambling game in two social contexts: an "audience" condition and an "alone" condition. The presence of others modulated the feedback-related negativity (FRN), which might reflect enhanced motivational significance or increased reward processing when participants were watched compared to when they were alone. We also observed increased P300 responses to outcome feedback in the audience condition, presumably reflecting more elaborative and sustained evaluation of outcomes in the audience than alone context. This audience effect on the evaluative processes complements previous observations on the social nature of outcome evaluation and extends a traditional topic in social psychology to the neuroscientific field. (C) 2015 Elsevier B.V. All rights reserved
Hair cortisone level is associated with PTSD's dysphoric arousal symptoms in highly traumatized Chinese females
No full textBackground: Cortisone has been proposed as a useful additional biomarker for stress research. However, only very limited studies has investigated alterations of cortisone levels in stress-related mental disorder such as PTSD. The present study investigated the associations between PTSD symptomatology and hair cortisone levels which can reflect cumulative cortisone secretion over prolonged periods of time and is more robust to the influence of situational confounding
Access Repository Dashboard
Do you manage Institute of Psychology,Chinese Academy Of Sciences? Access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard!