Institute of Psychology,Chinese Academy Of Sciences
Not a member yet
6627 research outputs found
Sort by
Alterations in Regional Homogeneity of Spontaneous Brain Activity in Late-Life Subthreshold Depression
No full textThe early detection of major depression in elderly individuals who are at risk of developing the disease is of prime importance when it comes to the prevention of geriatric depression. We used resting-state functional magnetic resonance imaging (fMRI) to examine changes in regional homogeneity (ReHo) of spontaneous activity in late-life subthreshold depression (StD), and we evaluated the sensitivity/specificity performance of these changes. Nineteen elderly individuals with StD and 18 elderly controls underwent a resting-state fMRI scan. The ReHo approach was employed to examine whether StD was related to alterations in resting-state neural activity, in the form of abnormal regional synchronization. Receiver operating characteristic curve analysis and the Fisher stepwise discriminant analysis were used to evaluate the sensitivity/specificity characteristics of the ReHo index in discriminating between the StD subjects and normal controls. The results demonstrated that, compared to controls, StD subjects display lower ReHo in the right orbitofrontal cortex (OFC), left dorsolateral prefrontal cortex (DLPFC), left postcentral gyrus (PCG), and left middle frontal and inferior temporal gyri, as well as higher ReHo in the bilateral insula and right DLPFC. The left PCG and the right DLPFC, OFC, and posterior insula, together reported a predictive accuracy of 91.9%. These results suggest that the regional activity coherence was changed in the resting brain of StD subjects, and that these alterations may serve as potential markers for the early detection of StD in late-life depression
Action representation across ages and cultures: Recognition of action means-end change in German and Chinese children and adults
No full textActions can be represented as a hierarchy of goals and means, whereas the granularity of the top level depends on the action's complexity. So far, most evidence comes from imitation studies. We explored this issue by evaluating the detection of means and end changes in a recognition paradigm across ages and cultures. German and Chinese preschoolers (n = 53) and adults (n = 58) studied videos of tool-use actions differing in complexity and familiarity. In the test phase, participants judged identical, means-changed and end-changed actions as same or different. Changes of the actions' end were generally identified more accurately independent of age and culture. Means' changes, but not ends' changes, were detected more frequently for complex than for simple actions. Changes in familiar actions were recognised better than changes in unfamiliar actions. The data supports a hierarchical model of action representation where the end information is superordinate to means information
Altered phosphorylation of GluA1 in the striatum is associated with locomotor sensitization induced by exposure to increasing doses of morphine
No full textEscalation of drug consumption is involved in the transition from drug use to addiction. Our previous study demonstrated that neuronal activation in ventral tegmental area (VTA) and substantia nigra (SN) was associated with behavioral sensitization induced by increasing doses of morphine. Here we sought to characterize the molecular mechanism underlying this behavioral sensitization. We compared mitogen-activated protein kinase (MAPK) signaling following pretreatment with either increasing doses or fixed doses of morphine before and after behavioral sensitization. We found phospho-MAPK markedly increased in ventral striatum and decreased in dorsal striatum after either pretreatment group, but no further change after sensitization induced by 10 mg/kg morphine challenge. Furthermore, we also evaluated the level of phospho-glutamate receptor 1 at serine 845 (pSer845-GluA1) and 831 (pSer831-GluA1) sites in ventral striatum and dorsal striatum. The results showed a significant increase in pSer845-GluA1/GluA1 ratio in ventral striatum but not dorsal striatum after pretreatment with increasing doses of morphine but not after fixed-dose or saline pretreatment. Importantly, pSer845-GluA1/GluA1 ratio was increased exclusively in dorsal striatum and not ventral striatum following acute morphine challenge specifically paired with increasing-dose pretreatment and not fixed-dose or saline. These findings indicate that behavioral sensitization-induced by chronic pretreatment with increasing doses of morphine might be more closely associated with the dynamic GluA1 activity in the striatum rather than the modulation of MAPK signaling. These findings also indicate that GluA1 phosphorylation may occur independent of MAPK activation. (C) 2013 Elsevier B.V. All rights reserved
The Influence of Individual and Team Cognitive Ability on Operators' Task and Safety Performance: A Multilevel Field Study in Nuclear Power Plants
No full textWhile much research has investigated the predictors of operators' performance such as personality, attitudes and motivation in high-risk industries, its cognitive antecedents and boundary conditions have not been fully investigated. Based on a multilevel investigation of 312 nuclear power plant main control room operators from 50 shift teams, the present study investigated how general mental ability (GMA) at both individual and team level can influence task and safety performance. At the individual level, operators' GMA was predictive of their task and safety performance and this trend became more significant as they accumulated more experience. At the team level, we found team GMA had positive influences on all three performance criteria. However, we also found a "big-fish-little-pond" effect insofar as team GMA had a relatively smaller effect and inhibited the contribution of individual GMA to workers' extra-role behaviors (safety participation) compared to its clear beneficial influence on in-role behaviors (task performance and safety compliance). The possible mechanisms related to learning and social comparison processes are discussed
The Russian School Twin Registry (RSTR): Project PROGRESS
No full textThe Russian School Twin Registry (RSTR) was established in 2012, supported by a grant from the Government of the Russian Federation. The main aim of the registry is to contribute to Progress in Education through Gene-Environment Studies (PROGRESS). The formation of the registry is ongoing and it is expected that most schools in the Russian Federation (approximately 50,000 schools) will contribute data to the registry. With a total of 13.7 million students in Grades 1-11 (ages 7-18), the potential number of twin pairs exceeds 100,000. Apart from the large sample size and its representative nature, the RSTR has one unique feature: in collaboration with the International Advisory Committee to the Registry, genetically sensitive cross-cultural investigations are planned, aided by the use of the common assessment instruments. Other strengths of the registry include the assessment of a large sample of non-twin school children, including those studying in the same classes as the twins in the registry. It is hoped that the RSTR will provide an important research platform for national and international educationally relevant research
Learning without consciously knowing: Evidence from event-related potentials in sequence learning
No full textThis paper investigated how implicit and explicit knowledge is reflected in event-related potentials (ERPs) in sequence learning. ERPs were recorded during a serial reaction time task. The results showed that there were greater RT benefits for standard compared with deviant stimuli later than early on, indicating sequence learning. After training, more standard triplets were generated under inclusion than exclusion tests and more standard triplets under exclusion than chance level, indicating that participants acquired both explicit and implicit knowledge. However, deviant targets elicited enhanced N2 and P3 components for targets with explicit knowledge but a larger N2 effect for targets with implicit knowledge, revealing that implicit knowledge expresses itself in relatively early components (N2) and explicit, knowledge in additional P3 components. The results help resolve current debate about the neural substrates supporting implicit and explicit learning. (C) 2012 Elsevier Inc. All rights reserved
The roles of cognitive and motivational predictors in explaining school achievement in elementary school
No full textThe present study investigated the roles of cognitive (working memory, intelligence) and motivational variables (self-perceived ability, intrinsic value) in explaining school achievement. The sample consisted of N = 320 German elementary school children in the fourth grade. Working memory and intelligence were assessed in the classroom. Questionnaires including the motivational items were answered at home. Teachers provided midterm and endterm grades for the domains of German and Math. Using structural equation modeling, our main results indicated that across domains, both cognitive and motivational predictors explained substantial amounts of specific variance in school grades. The findings are, however, to some degree domain-specific in that cognitive variables were stronger predictors of Math (COG: beta = .59; MOT: beta = .41), whereas for German, motivational influences turned out to be better predictors (COG: beta = .34; MOT: beta = .67). Together, cognitive ability (including both WM and intelligence) and motivation (including self-perceived ability and intrinsic value) explained 75% and 71% of the variance in children's German and Math grades, respectively. (C) 2013 Elsevier Inc. All rights reserved
Access Repository Dashboard
Do you manage Institute of Psychology,Chinese Academy Of Sciences? Access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard!