399 research outputs found
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Human tendon-on-a-chip for modeling the myofibroblast microenvironment in peritendinous fibrosis
No full textPoster presented at the Orthopaedic Research Society Meeting in Phoenix, Arizona in February 2025. The contents include figures published in the Advanced Healthcare Materials paper linked below. We demonstrate the development of a tissue chip platform designed to study tendon inflammation and fibrosis. The poster figures detail the phenotype validation of the tendon-on-a-chip model and a proof-of-concept study to screen a potential therapeutic. </p
Love Data 2025: Persistent Identifiers in Scholarly Communication Networks - the ORCID Advantage
No full textThis webinar was recorded via Zoom on Wednesday, February 5, 2025.Persistent Identifiers or PIDs, are valuable pieces of information assigned to authors, articles, journals, books, funders, institutions, and other discrete elements embedded in scholarly communication or academic networks. PIDs are unique, open and interoperable, which makes them ideal to connect and distribute associated metadata seamlessly through the ecosystem. Join us to learn about the myriad ways you can use PIDs, such as ORCID, to promote your work and connect with others in academia.Mike Nason is the Open Scholarship and Publishing Librarian at the University of New Brunswick in Fredericton, New Brunswick, Canada. He is also the Metadata and Crossref Liaison with the Public Knowledge Project (PKP) and a PKP Publishing Services team member. He currently serves on the Coalition Publica technical committee and was the chair of their metadata working group, a two-year project to establish better metadata practices for the Coalition Publica membership and broader OJS community. Mike also chaired the ORCID-CA governing committee as part of the Canadian Research Knowledge Network (CRKN) consortium.This workshop is part of Love Data Month, run by the Data Services Team. This specific event is sponsored by the Open Scholarship Community Rochester (OSCR).</p
File and Folder Naming Guidelines
No full textFile-naming can be a deceptively challenging practice, juggling the need to provide useful information in the name without going overboard, ensuring that names are created consistently, that will they will be able to be interacted with programmatically, and ensuring that they don't require constant updating. The best practices outlined here attempt to take into account all of these considerations to create a durable, consistent, and informative set of parameters by which to create file names for digital assets.</p
Accessibly Create and FAIR(ly) Share Visualizations
No full textWant to make your visualizations more appealing and accessible? Do you wonder how visualizations can be shared in a FAIR way? In this interactive workshop participants will explore strategies to determine the accessibility of a graph, learn tips for creating accessible graphs, and create their own visualizations with Excel and Tableau. With hands-on exercises, participants will experience the full data visualization cycle, from creating their graphs with accessibility in mind, to preparing their documentation and tables and sharing them.As data sharing becomes increasingly prevalent, it is imperative that data professionals become knowledgeable on how visualizations can be shared in a way that is FAIR, but also accessible to individuals with disabilities. Raw data and code receive the most attention when it comes to ensuring research is FAIR, but visualizations should also receive the same treatment. While data and code increase the reproducibility of research, it is the visualizations that make it understandable to the general public. This workshop will help bridge this gap, and encourage data professionals to broaden the types of research outputs they assist researchers with.This workshop was presented via Zoom on 2025/01/23 for the Research Data Access & Preservation Association's (RDAP) 2025 webinar series. To access the webinar recording, which can be found here, you must be a current RDAP member.</p
Data Bloom 2025: PivotTables, PivotCharts, and Dashboards in Excel
No full textData Bloom: PivotTables, PivotCharts, and Dashboards in Excel was presented via Zoom on Thursday, October 23, 2025 as part of the Fall 2025 Data Bloom workshop series.Workshop Description: How familiar are you with PivotTables and PivotCharts in Excel? Did you know you can create a dashboard in Excel? Whether you are a beginner or an intermediate user, come join our workshop on PivotTables, PivotCharts, and dashboards! Requested by the UR community, this updated version of previous Excel workshops will allow you to learn how to create accessible visualizations and dashboards live alongside our instructors. Beginner-friendly and welcome to Excel users of all skill levels, please feel free to attend even if you cannot stay the entire time.The current recording is unedited and does not have captions so it could be shared in a timely manner. Once captions have been added the recording will be reuploaded.</p
Raw data for Design, Fabrication, and Characterization of a Microbubble Array Microphysiological System
No full textPCR and individual data point for cell cluster for Fig 7</p
Dataset for analysis with RMD file in "Antibody Responses to SARS-CoV-2 and Common HCoVs in Hemodialysis Patients and Transplant Recipients: Data from the Dominican Republic."
No full textThe dataset supports the article "Antibody Responses to SARS-CoV-2 and Common HCoVs in Hemodialysis Patients and Transplant Recipients: Data from the Dominican Republic" published on September 11, 2025 in VaccinesResearch Abstract:Background: Vaccination against SARS-CoV-2 has been pivotal in controlling the COVID-19 pandemic. However, understanding vaccine-induced immunity in immunocompromised individuals remains critical, particularly how prior exposure to other coronaviruses modulates immune responses. The influence of previous infections with endemic human coronaviruses (HCoVs), such as OC43, on SARS-CoV-2 immunity is not fully understood. This study evaluates antibody responses to COVID-19 vaccination in hemodialysis patients (HD), transplant recipients (TR), and healthy controls (CO), accounting for prior SARS-CoV-2 infection and baseline human coronavirus (HCoV) reactivity. Methods: We obtained longitudinal antibody measurements from 70 subjects (CO: n = 33; HD: n = 13; TR: n = 24) and assessed antibody kinetics across multiple post-vaccination time points using multivariate linear mixed modeling (MLMM). Results: Limited but measurable cross-reactivity was observed between SARS-CoV-2 and endemic HCoVs, particularly the -coronavirus OC43. Pre-existing immunity in healthy individuals modestly enhanced vaccine-induced anti-spike (S) IgG responses, supported by post-vaccination increases in SARS-CoV-2 IgG. Prior SARS-CoV-2 infection significantly influenced anti-S and nucleocapsid (N) IgG responses but had limited impact on endemic HCoVs responses. Vaccine type and immune status significantly affected antibody kinetics. mRNA vaccination (BNT162b2) elicited stronger and more durable SARS-CoV-2 anti-S IgG responses than the inactivated CoronaVac vaccine, especially in immunocompetent individuals. Immunocompromised groups showed delayed or attenuated responses, with modest anti-S IgG cross-reactive boosting. Elevated anti-N IgG in CoronaVac recipients raised questions about its origin—infection or vaccine effects. MLMM identified key immunological and clinical predictors of antibody responses, emphasizing the critical role of host immune history. Conclusions: These findings highlight a constrained but meaningful role for HCoV cross-reactivity in SARS-CoV-2 immunity and vaccine responsiveness, underscore the need for infection markers unaffected by vaccination, and support development of broadly protective pan-coronavirus vaccines and tailored strategies for at-risk populations.</p
The Modular μSiM: insituPerm_Optimization
No full textData compilation for setting optimization for in situ permeability assay developed in publication and presented in supplement of: The Modular µSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro</p
The Modular μSiM: AdhesionMoleculeICC_UR_SupplementFig_PNGFiles
No full textImage files for adhesion molecule ICC obtained at UR for supplemental figure in The Modular µSiM: A Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro</p
The Modular μSiM: SamplingPerm_hCMECD3_10kDaDex_20210705.xlsx
No full textRaw data files (excel) for sampling or in situ permeability assaysRaw data (excel) files for in situ and sampling permeabiiity across hCMEC/D3 monolayers for The Modular μSiM: A Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro</p