DIGITUM Repositorio Institucional de la Universidad de Murcia
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Technological use, didactic intentionality and attitudes towards learning mathematics with technology in public and private school students
No full textEducational technology contributes to the improvement of the quality of education, playing a crucial role in the teaching of abstract content such as Mathematics. This study sought to determine how the use of technology by teachers influences the perceived didactic intentionality of students and their attitudes towards learning mathematics with technology, considering whether these relationships vary according to the type of school (public or private). Using an explanatory design with latent classes, 1,326 Colombian schoolchildren (685 girls) were evalua-ted through a series of surveys. A Structural Equation Model was generated and showed good fit (CFI = 0.982, TLI = 0.966, RMSEA = 0.050), supporting the study hypotheses. Regression coefficients indicate that perceived didactic intentionality influences student attitudes in both educational contexts, but technological use has no relevant effect among public school students. The implications of the technological strategies employed by teachers to teach Mathematics and the intentionality perceived by their students are discussed, as well as the impact of contex-tual differences on the guarantee of an equitable educational service for students from diverse socioeconomic contexts.La tecnología educativa aporta a la mejora de la calidad formativa, cumpliendo un papel crucial en la enseñanza de contenidos abstractos como las matemáticas. Este estudio buscó determinar cómo el uso de tecnología por parte del personal docente influye en la intencionalidad didáctica percibida de los y las estudiantes y en sus actitudes hacia aprender matemáticas con tecnología, considerando si estas relaciones varían según el tipo de escuela (pública o privada). Mediante un diseño explicativo con clases latentes, se evaluó a 1326 escolares colombianos (685 chicas) por medio de una serie de encuestas. Se generó un Modelo de Ecuaciones Estructura-les que demostró un buen ajuste (CFI = 0.982, TLI = 0.966, RMSEA = 0.050), respaldando las hipótesis de estudio. Los coeficientes de regresión indican que la intencionalidad didáctica percibida influye en las actitudes estudiantiles en ambos contextos educativos, pero el uso de tecnología no tiene un efecto relevante en las actitudes del alumnado de escuelas públicas. Se discuten las implicaciones de las estrategias tecnológicas empleadas por los docentes para enseñar matemáticas y la intencionalidad percibida por sus estudiantes, así como el impacto de las diferencias contextuales en la garantía de un servicio educativo equitativo para alumnos de diversos contextos socioeconómicos
Serra, C. (2024). El sentido de consentir. Barcelona: Anagrama, 136 pp. [Reseña bibliográfica]
No full textEs reseña del libro El sentido de consentir / C. Serra. Barcelona: Anagrama, 202
Dynamic Lysine Acetylation Disrupts Isocitrate Lyase Function and Enables Metabolic Optimisation
No full textProteomic studies have suggested that Escherichia coli isocitrate lyase (ICL) undergoes multiple acetylation events, partially inhibiting its activity. However, the molecular basis of this regulation and the contribution of individual lysine residues had not been defined. This study demonstrates that acetylation of ICL in E. coli is acetyl-phosphate–dependent and reversible by the CobB deacetylase, establishing a key post-translational regulatory mechanism within the glyoxylate shunt. Site-specific acetylation at K13 and K308 inhibits ICL activity by destabilising the tetrameric assembly and rendering the protein more prone to degradation, whereas lysine-to-arginine substitutions at these positions alleviate this inhibition, enhancing carbon flux distribution, metabolic flexibility and biomass yield without the burden of plasmid-based overexpression. Leveraging this regulatory insight, a KR mutant bearing lysine-to-arginine substitutions at residues 13 and 308, engineered directly into the chromosomal aceA gene, maintained wild-type growth rates while reducing acetate overflow and improving metabolic balance during glucose depletion and acetate assimilation, leading to a 61% increase in lycopene production. These findings highlight regulatory-based metabolic engineering as a powerful strategy to optimise bioproduction and pave the way for extending this approach to other central metabolic enzymes to develop robust microbial cell factories for the sustainable synthesis of biofuels, biochemicals and high-value compounds
Glyphs consigue el Goudy Award 2026, que reconoce aportaciones clave a la tipografía
No full textGeorg Seifert y Rainer Erich Scheichelbauer, socios y creadores de Glyphs, recibirán el Frederic W. Goudy Award 2026, uno de los reconocimientos académicos más consolidados en el ámbito de la tipografía y sus disciplinas afines
Do governance structures drive green building adoption? A machine learning approach with random forests
No full textThis study examines the determinants of firms' propensity to adopt green buildings in the Euro Stoxx 300 and the S&P 500 indices, during 2012–2023. Using random forest binary classifiers, we assess the relative importance of financial, sectoral, geographic, and climate governance predictors and uncover nonlinear relationships often overlooked by econometric approaches. Results show that sectoral affiliation is the most influential determinant in both markets. Governance-related predictors are collectively highly influential, although they exhibit different patterns across institutional contexts. In Europe, the presence of a Sustainability Committee charged with climate strategy is the most influential factor, whereas in the United States, nonfinancial/environmental performance disclosure plays a prominent role. CEO-related mechanisms show asymmetric effects. Other board characteristics, such as gender diversity, independence, size, skills, experience, turnover, meetings, and remuneration, also matter, but their impact varies by institutional context. Overall, the findings highlight that corporate governance plays a decisive yet asymmetric role in sustainable-building adoption
Patriarchal masculinity, antisocial behaviour and public health. An analysis from feminist political philosophy
No full textLa conducta antisocial es ejercida mayoritariamente por los hombres en todo el mundo. No solo generan la mayor parte de las víc-timas asistidas por los sistemas sanitarios, sino que también impactan personalmente sobre los mismos como consecuencia de su desarrollo de hábitos nocivos para la salud. Estos hechos constituyen simultáneamente un problema de justicia social y un problema de salud pública. Los estudios de género han demostrado que las conductas antiso-ciales ejercidas por los hombres no están determinadas biológicamente, sino que son el resultado de una cultura de masculinidad originada por la estructura patriarcal de dominación/discriminación de las mujeres. Esta perspectiva interpela a los Estados democráticos en lo que refiere al desarrollo de políticas de igualdad dirigidas a los hombres, puesto que sus principios regulativos de Libertad, Igualdad y Solidaridad no podrán ser materializados hasta que la transformación social de los hombres hacia la igualdad sea un hecho
Astrocyte heterogeneity and gliosis in Huntington’s disease: Histopathological insights into striatal and white matter pathology
No full textHuntington’s disease (HD) is a devastating,
autosomal dominant neurodegenerative disorder
characterized by progressive motor dysfunction,
cognitive decline, and psychiatric disturbances. Among
the major pathological hallmarks of HD are mutant
huntingtin aggregation, white matter loss and reactive
astrogliosis, which together contribute to neuronal
dysfunction and death, particularly in the striatum and
cortex. Recent studies in HD mouse models have
identified a specialized astrocyte subtype that clusters
around white matter bundles originating from the
secondary cortex and passing through the striatum.
While the functional role of these astrocytes remains
unclear, they express Glial Fibrillary Acidic Protein
(GFAP), a marker typically associated with both fibrous
and reactive astrocytes. The discovery of this white
matter-associated astrocyte subtype, along with other
astrocytic subtypes differing between grey and white
matter, underscores the complexity of glial responses in
HD. Accurate identification and interpretation of these
glial populations are crucial for understanding disease
mechanisms and progression. Given the overlapping
expression profiles of commonly used astrocyte markers
like GFAP, the careful selection and application of both
astrocyte and white matter markers in histopathological
analyses are essential to advance our understanding of
how glial cells contribute to HD pathology. In this
review we discuss different histopathological approaches
to assess the roles of glia in HD, emphasizing the need
for standardized approaches and critical evaluation of
marker specificity
A Study of Special School Teachers’ Perceptions of the CRPD and Inclusive Education
No full textIntroduction: In recent years, the debate on school inclusion has intensified, with a solid regulatory framework that contrasts with a reality in classrooms marked by inequalities, heterogeneous practices, and tensions between principles and context. Objective: The aim is to describe teachers' inclusive knowledge in special education contexts.Methodology: quantitative, non-experimental, cross-sectional study with a sample of 123 teachers from the Murcia region, administered online using descriptive analysis, Spearman correlations, and Kruskal Wallis.Results:there is a high presence of students with sensory difficulties; declared universal teaching knowledge, but limited assessment skills from a UDL perspective.Conclusions: teachers have solid normative and planning bases, but criticism persists regarding inclusive assessment practices and attitudes, suggesting specific training needs and future studies with larger samples.Introducción: en los últimos años, el debate sobre la inclusión escolar se ha intensificado, contando con un marco normativo sólido, que se contrapone a una realidad en las aulas marcada por las desigualdades, las prácticas heterogéneas y las tensiones entre los principios y el contexto. Objetivo: describir los conocimientos inclusivos de los docentes en centrosde educación especial.Metodología: estudio cuantitativo, no experimental y transversal, con una muestra de 123 docentes decentros de educación especial dela región de Murcia, empleando un análisis descriptivo, correlaciones de Spearman, Kruskal Wallis.Resultados: existenconocimientos didácticos declarados universales, pero competencias de evaluación desde la perspectiva de la DUA limitadas. Conclusiones: los profesores cuentan con bases normativas y de planificación sólidas, pero persisten las críticas en las prácticas de evaluación inclusivas y en las actitudes, lo que sugiere necesidades de formación específicas y estudios futuros con muestras más amplias
Investigación Epidemiológica de Brotes de Enfermedad Transmitida por Alimentos
Full text linkEste documento es la actualización del depositado en 2025-03-10Documento con los contenidos aportados por el profesor, como complemento al tema teórico de " Investigación Epidemiológica de Brotes de Enfermedad Transmitida por Alimentos
Fatphobia, legal orders, and bodies that resist: A comparative socio‑legal inquiry into France and Spain
No full textThis article examines fatphobia as a form of structural violence at the intersection of law, health, and culture, through a comparative analysis of France and Spain. Drawing on a theoretical framework that brings together biopower (Foucault), feminist and decolonial critiques of the body (Bordo; Strings; Vergès; Moreno Figueroa), and the notions of stigma (Goffman) and bodily/erotic capital (Bourdieu; Moreno Pestaña), I argue that law operates as a somatocratic technology: by adopting weight-centric biomedical parameters (e.g., BMI), it legitimizes the exclusion of fat bodies in employment and healthcare settings. Methodology: documentary analysis of legislation and public policies, and a selective review of case law and institutional reports (FR/ES). Findings: (i) both legal systems rely on general equality principles and lack explicit recognition of fatphobia as a protected category; (ii) in France, the category “physical appearance” and the role of the Défenseur des droits have fostered a nascent institutionalization of the issue; (iii) in Spain, sporadic jurisprudential advances coexist with regulatory gaps. Conclusion: a bodily justice agenda is proposed, including the legal recognition of fatphobia as a ground of discrimination, the revision of exclusionary bodily requirements, and legal education with an intersectional approach