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Journal of African Christian Biography: v. 9, no. 2/3: Separate cover file (Word), print-ready
No full textThe full issue of Journal of African Christian Biography: v. 9, no. 2/3 is available at: https://hdl.handle.net/2144/4920
Description and Implementation: Cardiac Pathophysiology
No full textImplementation guide for cardiac pathophysiology educational resources that correlate bedside cardiac assessment findings with underlying disease mechanisms. This module teaches learners to understand the relationship between physical examination findings and the pathophysiology associated with aortic dissection, pulmonary edema due to acute coronary syndrome, and mitral stenosis in pregnancy.
Includes “The Cardiac Cycle” (Learning Set M), where a cardiologist relates the basic electrocardiogram, visual hemodynamics, and diagrams to murmurs and gallops, providing deeper understanding of the pathophysiology behind heart sounds and their mnemonics. Also includes three clinical cases linking bedside cardiac assessment findings to pathophysiology.
Can be completed as self-directed learning (40 minutes) or facilitated small- or large-group discussion (60 minutes). Suitable for medical students, PA and NP students, and residents learning cardiovascular pathophysiology.[Type: Learning Resource; Educational Level: Medical Student, PA Student, NP Student, Resident; Learning Resource Type: Implementation Guide, Video Module, Case Studies; Time Required: PT40M (self-directed) or PT1H (facilitated); Educational Use: Self-Study, Group Discussion, Pathophysiology Integration
Journal of African Christian Biography: v. 3, no. 2: Separate cover file (Word), print-ready
No full textThe full issue of Journal of African Christian Biography: v. 3, no. 2 is available at: https://hdl.handle.net/2144/3567
Version française : Njoko David : L’arbre qui cache la forêt
No full text[Njoko David (né Mabumba Agadibu) était un jeune téméraire et convaincu de ses actes qui est devenu un des principaux artisans de la station missionnaire mennonite de Mukedi. Mukedi était la station-mère de la Congo Inland Mission (CIM) – devenue plus tard la Communauté mennonite au Congo (CMCo) – dans la province administrative actuelle du Kwilu.
Journal of African Christian Biography: v. 7, no. 4: Booklet, no cover (A4 format), print-ready
No full textThe full issue of Journal of African Christian Biography: v. 7, no. 4 is available at: https://hdl.handle.net/2144/4524
An Interpretative Phenomenological Analysis of the lived experiences of eight gay cisgender PK–12 music educators
No full text2025In this study, I examined and described the lived experiences of eight gay music educators teaching in PK–12 public schools in the United States. Using Interpretative Phenomenological Analysis (IPA), I sought to examine and understand the complexities of participants’ lived experiences and how the participants made meaning of those experiences. Highlighted in this study are the challenges and contexts that gay music educators face within the structures of patriarchal and heteronormative educational environments. Using semi-structured interviews, the participants disclosed how they made meaning of their lived experiences as gay, cisgender males who were also music educators. Using IPA, I elicited from the participants their interpretation of—and perspective on—their personal, professional, and social relationships. I uncovered the phenomenological, hermeneutic, and idiographic effects of working as a music educator in a public school system where White patriarchal and heteronormative values have long predominated. In turn, the examination of the lived experiences of these eight gay music educators is essential for aiding educational policymakers and administrators in shaping policies and practices supportive of a specific minority group while also encouraging the need for the study of other minority groups through this research method
Microwaves for bi-modal neuromodulation: mechanisms and translation
No full text2025Electrical neuromodulation, the current clinical standard, is invasive, expensive, and prone to malfunction. A broad range of electromagnetic waves have been investigated for noninvasive neuromodulation, but existing methods are limited by the tradeoff between penetration depth and spatial precision. Microwaves in the 0.1 – 6 GHz range are widely used for telecommunications and can penetrate to the deep brain. Microwaves have been shown to nonthermally modulate neural activity, but the acute bioeffects remain unclear and under-studied. Additionally, microwaves alone do not provide sufficient spatial precision to modulate target neurons without affecting surrounding tissues. In this thesis, we have developed two miniature microwave resonators – the split-ring resonator (SRR) and the microwave-powered injectable neuromodulation implant (MINI) – which generate enhanced microwave fields with submillimeter spatial precision. With the SRR and the MINI, microwaves at dosages below the safe exposure limit are shown to modulate neuronal activity. First, we employ the microwave resonators to demonstrate bi-modal neuromodulation via thermal and nonthermal mechanisms. Next, using the microwave resonators, we perform electrophysiological recordings of neurons exposed to microwaves to elucidate the differential effects of pulsed and continuous microwaves on neurons. Finally, we demonstrate an application of precision microwave neuromodulation in an in vivo model of epilepsy
Dataset for article: the chemical identification of cochineal production tools in archaeological environments: preservation, degradation, and contamination
No full textA live-cell reporter to track Drosophila innate immunity reveals heterogeneity in NF-κB activation and target gene expression
No full text2025Conserved NF-κB signaling pathways are critical for shaping innate immune responses across species. Yet, we lack a complete understanding of how pathway elements generate diverse responses to varying stimuli. Defining the origins and consequences of this heterogeneity can improve strategies for predicting and managing infection outcomes. Drosophila melanogaster is a powerful model organism for studying innate immunity due to its conservation of key signaling pathways and lack of adaptive immune response masking. In this dissertation, I develop and use live Drosophila S2* reporter cells to investigate the spatiotemporal dynamics of the IMD innate immune pathway, which responds to Gram-negative bacterial cues and activates the NF-κB transcription factor Relish. I engineer single-cell reporters that simultaneously track Relish and transcription of antimicrobial peptide (AMP) genes under its control. Using this system, I discover distinct categories of Relish spatiotemporal dynamics, governed in part by pre-stimulus cell states, and show that these behaviors predict transcriptional outcomes. I further demonstrate that AMP gene enhancer architecture, particularly the number of κB-binding motifs, tunes transcriptional activity, and that AMP expression exhibits gene-specific burst kinetics. Additional experiments rule out oscillatory signaling and rapid protein turnover as sources of heterogeneity, instead implicating negative feedback regulation. Together, this work reveals that NF-κB signaling and downstream transcription in Drosophila innate immunity are both heterogeneous and tunable. These findings establish a new framework for studying innate immune regulation at single-cell resolution and open avenues for cross-species comparisons of immune strategies
Anticyclotomic Iwasawa invariants and congruences of modular forms
No full text2013The main purpose of this dissertation is to examine how congruences between Hecke eigensystems of modular forms on the unit group of a definite quaternion algebra affect the Iwasawa invariants of their anticyclotomic p-adic L-functions. This work can be regarded as an application of Greenberg-Vatsal and Emerton-Pollack-Weston's ideas on the variation of Iwasawa invariants under congruences to the anticyclotomic setting. As an application, based on Pollack-Weston's generalization of Bertolini-Darmon's work, this work establishes infinitely many new examples of the anticyclotomic main conjecture for modular forms, which are not treated by Skinner-Urban's work. The idea comes from the philosophy of congruences developed by Vatsal, Greenberg-Vatsal, Greenberg, and Emerton-Pollack-Weston. We remark that our setting is more general than that of Skinner-Urban's work in two ways. First, the fixed prime p does not necessarily split in the imaginary quadratic field K. Second, our ramification condition on the residual Galois representations is weaker than Skinner-Urban's one. Note that the second condition allows us to deal with the case of positive mu-invariants