Biodiversity Informatics
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Elevated Peripheral Blood Mononuclear Cell-derived Superoxide Production in Middle-age/Older Women with Obesity and Hypertension
Identifying Barriers to Mental Health Care For Canadian Student-Athletes: A Narrative Approach
Canadian student-athletes and American college athletes face unique stressors related to their sport and have demanding schedules. Although there is limited research specifically focused on the mental health of Canadian student-athletes participating in university sports, existing studies indicate that Canadian student-athletes report increased levels of psychological distress and are more susceptible to mental health issues compared to the general student population. Despite this, many do not seek or receive the treatment they need. This study aimed to identify the barriers to mental health care for Canadian student-athletes competing in Canada. Using a narrative approach, participants identified barriers to mental health treatment, including cultural stigma and voluntary isolation, in addition to a lack of availability of mental health services and the suffering of Canadian student-athletes
Student-Athletes’ Road to Success in College Life: Factors Influencing Psychological Well-being, Athletic, and Academic Performance
This study examined factors influencing college student-athletes’ athletic and academic performance built upon self-determination theory and the theory of planned behavior. With intrinsic and extrinsic motivation for collegiate athletics, student-athletes can shape attitudes, subjective norms, and perceived control, fostering psychological well-being. Psychological well-being could influence performance in athletics and academic achievements. Voluntary student-athletes contacted by coaches participated in the survey. A total of 262 responses from NCAA Division I schools were collected. A mixed-methods approach, consisting of survey responses and interview data, was implemented. Results found psychological well-being played the most salient role in explaining student-athletes\u27 athletic and academic performance self-assessments. With self-growth motivation (intrinsic), the "I can do" spirit was positively related to their psychological well-being, which triggered better athletic and academic performance. Inspirational role models (extrinsic motivation) also prompted psychological well-being. Intrinsic motivation independently affected student-athletes’ self-assessed academic performance. The findings suggest self-reliant growth, supportive inspiration, and a success mindset explain student-athletes’ disciplined fulfillment, competence, and compassion for current and future development in collegiate athletic and academic lives
Diagnostic Challenges and Key insights of Nitrous Oxide Neuropathy: A Case series
Nitrous oxide (N₂O) is increasingly misused due to its easy availability. Chronic misuse causes irreversible oxidation of cobalamin which results in vitamin B12 deficiency and impaired myelination leading to neurological complications. We present two cases highlighting diagnostic challenges consisting of a 34-year-old male and a 52-year-old, both initially misdiagnosed as chronic inflammatory demyelinating polyneuropathy (CIDP). They were eventually diagnosed as N₂O-induced neuropathy based on lab testing and electrodiagnostic findings. Clinicians should maintain a high suspicion of N₂O misuse in unclear neuropathies. Early recognition with prompt and sustained vitamin B12 supplementation is crucial for preventing irreversible neurological damage and avoiding unnecessary immunotherapy
Interspecific amplexus of a male Himalayan Toad, Duttaphrynus cf. himalayanus (Gunther 1864), and a female Asian Common Toad, Duttaphrynus melanostictus (Schneider 1799), in West Kameng, Arunachal Pradesh, India
A Great Black Hawk (Buteogallus urubitinga) preying on a Marine Toad (Rhinella marina) in Yasuni National Park, Ecuador
Predation on a Common Basilisk (Basiliscus basiliscus) by a Bare-throated Tiger Heron (Tigrisoma mexicanum) in Costa Rica
RFDiffusion: Revolutionizing Protein Design with Generative AI
Protein design is an intricate and essential frontier in biotechnology, offering the potential to revolutionize medicine, materials science, and our understanding of biological systems. At its core, protein design involves crafting proteins with specific structural or functional properties. These tasks include creating enzymes with catalytic activity, designing protein binders to interact with specific targets, and engineering scaffolds that stabilize biologically relevant motifs. For years, traditional methods of protein design relied heavily on physics-based simulations and iterative experimental testing. While groundbreaking, these approaches were often computationally expensive and limited in their ability to explore the vast diversity of protein structures