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Empowerment through architecture: women’s transitional cohousing in Northern Ontario
No full textThis thesis is a response to the lack of supportive post-intervention housing for women who have survived
domestic violence. In Canada, 76.2% of the women
who are murdered, are killed by a spouse, family
member or intimate partner. Women are statistically
at a higher risk of being killed by someone they are
close to than their male counterparts. As a result of
experiencing violence, they require new housing and
support as their previous residence is not an
appropriate place to return. Additionally, having an
affordable and safe housing option when vulnerable
situations arise is important for women, so safety does
not need to be compromised for the sake of urgent
need or financial circumstances. This presents the need
for housing options for women transitioning out of
vulnerable situations. Women are celebrated in the
proactive and reactive supportive housing model that is
explored in the design proposal for the Women’s
Transitional Cohousing
La pensée critique en éducation physique et à la santé (EPS) : sens et utilité?
No full textQuel est le portrait de la pensée critique dans l’agir professionnel des
enseignants d’EPS ? Quel sens et quelle utilité a cette forme de pensée dans
une classe d’enseignement de l’EPS ? Basée sur la conception lipmanienne
de la pensée critique (Lipman, 1995, 2006), la présente étude tente d’émettre
des éléments de compréhension de la signification et de la portée de la pensée
critique lorsqu’elle est exprimée dans la pratique enseignante des éducateurs
physiques scolaires. Pour ce faire, neuf enseignements de classes d’EPS
délivrés par trois enseignants du secondaire ont fait l’objet d’observations et
d’explicitations via la technique de rappel stimulé. Les résultats révèlent que
la pensée critique déployée lors du processus enseignement-apprentissage,
bien qu’elle ait des expressions variables chez les enseignants, est essentielle
à la pertinence de l’acte éducatif de ceux-ci. Elle favorise, dans la plupart des
cas, l’apprentissage et l’éducation des élèves
Estimating overburden thickness in resistive areas from on-time airborne em data
No full textWe propose a method to invert two-component time-domain EM data to
a thick-sheet over half-space model, as a solution representing an overburden
on top of bedrock. We first estimated the conductivity of the lower half-space
using a combination of inversion for half-space (if appropriate) or a thin sheet
over half-space (also when appropriate). This yielded a number of estimates,
which could be combined to give a reasonable estimate of the lower half-space
conductivity for the survey area. With this estimation an equation solver was
used to solve the thick-sheet over half-space model for sheet thickness and
sheet conductivity. The output of the algorithm was generally stable when
applied to GEOTEM data in an area of moderately resistive overburden over a
generally more resistive half-space. Although it did not reliably reproduce the
overburden thicknesses as measured in the reference drill holes, it did give an
estimate that was reasonable in the conductive areas
De l’évaluation formative aux remédiations interactives immédiates à la gymnastique dans les collèges d’enseignement général de Segbeya et de Suru Lere.
No full textPour comprendre les adaptions opérées par les enseignants dans la gestion des classes à effectif
pléthorique, notre étude s’est fixée comme objectif, d’analyser les difficultés rencontrées au cours de la
remédiation interactive immédiate, réalisée en classe de gymnastique par les enseignants d’EPS des CEG
Sègbèya et Suru Léré. Pour mener à bien notre étude, nous avons emprunté une méthodologie axée sur
l’enquête par questionnaire, l’analyse des contenus et l’observation instrumentée. De l’analyse des résultats
obtenus, il ressort que : la mise en œuvre de l’évaluation formative en classe de gymnastique, continue de poser
d’énormes difficultés aux enseignants des CEG Sègbèya et Suru Léré. Ces difficultés sont relatives aux effectifs
des classes de 6ème de ces collèges qui accroissent les sollicitations des enseignants et affectent leur acquisition
des éléments gymniques. Pour s’adapter à de tels effectifs, les erreurs décelées au cours des évaluations
formatives sont immédiatement corrigées, grâce à l’activité de remédiation. Elle consiste à donner priorité aux
travaux de groupe et à développer des stratégies de travail en tutorat, permettant à la majorité des apprenants
de bénéficier d’une aide
Can magnetic susceptibilities measured on outcrops be used for modelling (and constraining inversions of) aeromagnetic data?
No full textMagnetic susceptibilities measured on outcrop and drill-core samples using hand-held
instruments have been shown in the literature to be useful for identifying mineralogical changes.
It is not yet clear how useful these measurements are for constraining magnetic modelling and
inversion. We have generated estimates of the apparent magnetic susceptibility of the ground by
mathematical transformation of an aeromagnetic data and assumed that these values can be used
to model the magnetic data. In the same area we have a large number of measurements on
outcrop and have compared these two independent estimates. When the measured values are
below 1x10-3 S.I., there is a no correlation between the measured and apparent values,
interpreted to be likely due to the influence or interference from nearby or underlying magnetic
sources. Hence, in this case the measured values cannot be used to constrain modelling and
inversion. When the measurements are above this value there is a limited correlation, with values
only agreeing to within a factor of about 10, so these values can be used as very rough
constraints. The poor correlation is interpreted as due to the presence of remanent magnetization
or heterogeneity of the magnetic susceptibility within the rock. A large database of outcrop
measurements gives an indication of the range of the variation in magnetic susceptibility values
that could be used in modelling
Cultural and architectural revitalization: a reinterpretation of Chinese tradition
No full textToronto’s downtown Chinatown was once the central core of Asian
culture and business in Canada but now has been superceded by
Markham’s opening of Pacific Mall and ongoing development of suburban
neighbourhoods. As a result, Toronto’s Chinatown Centre, a mall and
landmark in the heart of Chinatown, has significantly suffered as markets,
shops and restaurants have either closed or are now deprived of business
with no sight of recovery. Through a reinterpretation of core principles of
the traditional Chinese siheyuan, this thesis explores how architecture
can become a catalyst in the revitalization of Chinatown Centre, retaining
inherent qualities of Chinese culture through a narrative which could
be understood transgenerationally and transculturally. As geopolitical,
economical and technological implications forced the outsprawl of Chinese
communities to migrate out of downtown, the same factors could play a
significant role in bringing the Chinese communities back. The project
becomes a symbol and a physical reminder of Toronto’s resilience while
bringing awareness to the serious issue of the declining Chinatown Centre
Uncovering the therapeutic potential of Uncaria tomentosa using B16-BL6 mouse melanoma and 4T1 mouse breast cancer cells
No full textUncaria tomentosa (Rubiaceae), a medicinal plant native to Peru, has been
traditionally used for centuries as a treatment for a wide variety of diseases, as well as to
maintain health. It grows primarily in the Amazon rainforest and throughout South and
Central America. U. tomentosa extracts have been demonstrated to have anti-oxidant,
anti-apoptotic, anti-inflammatory and anti-cancer properties. The goal of this study was to
examine Uncaria tomentosa in both in vitro and in vivo models in order to evaluate its
potential anti-cancer activity using the B16-BL6 mouse melanoma and 4T1 mouse breast
cancer cell lines. Both ethanol and PBS extracts of U. tomentosa were prepared and used
to measure the effects on cell growth and survival using several different methodologies.
Treatment of cells with ethanol extracts was much more effective at inhibiting cancer cell
growth than treatment with PBS extracts in vitro, but no significant differences in the
cancer inhibitory effects were observed in vivo. The in vitro experiments showed that
treatment with the U. tomentosa extract significantly inhibited the growth of both B16-
BL6 and 4T1 cell lines. It also inhibited the expression of the Ki-67 proliferation marker and promoted cell death as measured by increased DNA fragmentation using TUNEL
assays in cancer cells. Treatment with the ethanol extract of U. tomentosa caused a
significant increase in the fraction of apoptotic cells in flow cytometry (i.e. sub G1
peaks). Furthermore, two animal experiments were performed in order to evaluate the
effect of U. tomentosa treatment on B16-BL6 cells in C57BL/6 mice. The results of the in
vivo experiments concluded that treatment with U. tomentosa reduced tumour weight and
tumour size. Histochemical analysis of the B16-BL6 tumours showed a strong reduction
in the Ki-67 cell proliferation marker and a small but not significant increase in DNA fragmentation in U. tomentosa-treated mice compared to the control. Further, U.
tomentosa extracts reduced staining for Factor VIII, a marker for endothelial cells,
indicating a decrease in angiogenesis in treated mice. Since U. tomentosa has been shown
to affect immune system function, the infiltration of several different immune cells into
the tumour was examined. No significant differences in the number of infiltrating T cells
(including T helper and cytotoxic T cells), B cells, or platelets were found between the
treated groups and the control. Collectively, the results in this study concluded that U.
tomentosa has potent anticancer activity that significantly inhibited cancer cell growth
both in vitro and in vivo. The discovery of new medicinal plants that are effective against
cancer cells may provide a strategy to develop cancer therapy and requires more
attention
A web-based intervention for perfectionism: an extension of previous findings
No full textTransdiagnostic interventions may be a beneficial approach for reducing a number of mental
health concerns. As such, the current study replicated and extended on a 10-week online
intervention for perfectionism to reduce perfectionism, depressive and anxious symptomology,
and negative affect using three groups: cognitive behaviour therapy (CBT), general stress
management (GSM), and no treatment (NT) waitlist. Moreover, a process and outcome approach
was used to monitor weekly changes in psychological functioning, while considering the role of
treatment readiness. At posttest, the CBT group exhibited greater adaptive changes in depressive
and anxious symptomology, and negative affect than the GSM and NT groups. Although the
CBT group exhibited declines on cognitively-focused perfectionism indicators and some traitlike perfectionism indicators, the GSM group exhibited more adaptive changes on most
perfectionism indicators. Treatment adherence and treatment readiness are discussed as possible
contributors to treatment outcomes and attrition
A metagenomic analysis of tailings microbial communities from both cold and hot environments
No full textMining practices produce a substantial waste product in the form of tailings, a problematic
liability particularly in materials where iron and sulfur become oxidized leading to acid mine
drainage (AMD). Native microbial consortia in tailings sites accelerate this oxidation by a factor
of 106. The oxidative capabilities of these consortia can be harnessed to bioleach low-grade,
refractory metals from the waste materials while also allowing for the potential stabilization of
nuisance elements. This project explores the contributions of native microbes isolated from
sulfide tailings from two different climates: colder climate tailings around Sudbury, Ontario and
warmer climate arsenopyrite refractory gold tailings from Ecuador (ECT). The cold community
project encountered technical challenges as is summarized here as an appendix. This thesis
focuses primarily on the ECT community. The ECT tailings were enriched in medium ahead of
bioleaching trials and a metagenomic analysis was performed to identify key organisms
responsible for driving bioleaching. The main contributors to the ECT system at the order level
were Acidithiobacillales, Bacillales, Burkholderiales, Clostridiales, and Thermoplasmatales. The
dominant organisms representing these orders were found to have complementary genetic
systems that drive iron and sulfur oxidation. Understanding these key players will help optimize
the conditions that the ECT culture will be applied in using stirred-tank bioreactors and will
provide the baseline metagenomic information to help monitor the health of these organisms
throughout bioleaching campaigns
Water source of concern: an architectural response to the implications of the Winnipeg Aqueduct on a way of life in Shoal Lake 40 First Nation
No full textThis thesis focuses on the community of Shoal Lake 40 First Nation
in Northwestern Ontario and the impact of the Winnipeg Aqueduct on a way
of life. This thesis aims to present an architectural response which provides a
restorative environment for a community, as well as developing a sustainable
economy within that community. The main architectural response includes
a water purifcation centre, a community greenhouse and a constructed
wetlands park. Potable water will then be available to the community’s
residents. Once this is established the second phase will be an eco-lodge that
incorporates the living museum previously established within the community,
along with a series of cabins, as this will promote eco-tourism. A series of
landscape and low impact design strategies are also planned throughout the
proposal across a spectrum of design scales, from the master plan, to the
building scale, including the ecological. Through these phased interventions
over time, the community of Shoal Lake 40 First Nation will frst provide
potable water to its residents, and then subsequently continue to develop a
sustainable communit