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Fetal alcohol spectrum disorder: diagnostic outcomes in Northeastern Ontario
Get PDFThe current document is a paper-based thesis examining the diagnostic outcomes of children and
youth who presented for Fetal Alcohol Spectrum Disorder (FASD) assessment in Northeastern
Ontario. While past research has identified many functional difficulties and challenges that are
associated with FASD, little is currently known about this population in Northeastern Ontario.
Therefore, as part of a nation-wide FASD initiative conducted by the Canada FASD Research
Network (CanFASD), the current study employed a retrospective chart review and secondary
data analysis of children and youth who have been assessed for FASD at the Sudbury FASD
Diagnostic clinic, which services the Northeastern Ontario region. The first paper is a descriptive
overview of those who presented for FASD assessment, and further compares the individuals
who received an FASD diagnosis and those who did not. Findings demonstrate a need to support
individuals with prenatal alcohol exposure through multiple service entities within the region.
The second paper examines the intelligence quotient (IQ) scores and related adverse outcomes
among the children and youth in the sample who received an FASD diagnosis. Findings support
the known weakness with IQ in describing the difficulties and needs of individuals with FASD,
and further highlight the importance of an early diagnosis to lessen the risk of adverse outcomes.
Suggestions for future research and clinical implications are also discussed
The effect of hydrogen sulfide on glycolysis-based energy production and mouse red blood cell survival
Get PDFHydrogen sulfide (H2S), a gasotransmitter that modulates physiological and pathophysiological
processes, has recently been shown to promote aerobic energy production in the mitochondrion
in response to hypoxia. Its effect on anaerobic energy production, however, has yet to be
established. Glycolysis is the anaerobic process by which ATP is produced through the
metabolism of glucose. The purpose of this study was to establish the effect of H2S on
glycolysis-mediated energy production in mouse RBCs, which are mitochondrion-free. This
study demonstrated the capacity of mouse RBCs to produce H2S via 3-mercaptopyruvate
sulfurtransferase (MST). Both exogenously administered H2S salt (NaHS) and MST-derived
endogenous H2S stimulated glycolysis-mediated ATP production. The effect of NaHS on ATP
levels was oxygen-independent. However, hypoxic stress stimulated MST activity in mouse
RBCs. High concentrations of NaHS (300-1000 μM) prolonged cell viability but reduced ATP
levels. H2S may offer a cytoprotective effect in mammalian RBCs to maintain oxygenindependent energy production.Master of Science (MSc) in Biolog
Effect of culture on the conception of nature and the role of critical thinking, as well as on the didactic-pedagogical devices of its development in SPE setting: C ase of Algeria.
No full textLe développement de la pensée critique est un objectif éducationnel prioritaire
dans la plupart des curriculums scolaires de plusieurs pays. La pensée critique outillera
les élèves non seulement à faire face à la complexité du XXIe siècle mais aussi à
mieux s’adapter aux circonstances de leur vie future. Le but de la recherche était de
tenter de mieux comprendre l’effet de la culture sur les conceptions des enseignant-e-s
d’EPS à l’égard de la nature et du rôle de la pensée critique, de même que des
modalités de son développement en EPS dans le contexte scolaire algérien. Quinze
(15) enseignant-e-s d’EPS du 1er et du 2e cycle du secondaire (collège et lycées) ont
participé à l’étude. Deux techniques de collecte de données (l’entrevue individuelle et
le focus group) ont été utilisées. Le corpus recueilli a été analysé selon la stratégie
d’une analyse de contenu. Plusieurs résultats ont émané de la recherche, entre autres :
a) le curriculum est favorable à la notion de pensée critique, b)le programme d’études
en ÉPS est défavorable à la notion de pensée critique, c) il y a l’influence de la culture
du pays (la religion, l’impact du genre, les coutumes et les traditions) sur la pensée
critique des enseignants et des élèves, d) le milieu culturel (famille, école, la société
Algérienne) ne motive pas au développement et/ou à l’expression d’une pensée critique des élèves, e) la conception de l’EPS dans la société algérienne est vue comme une discipline d’amusement, de défoulement et une matière secondaire = The development of critical thinking is a priority educational objective in most
school curricula in several countries. Critical thinking will equip students to not only
cope with the complexity of the 21st century but also to better adapt to the
circumstances of their future lives. The aim of the research was to try to better
understand the effect of culture on the conceptions of PE teachers with regard to the
nature and role of critical thinking, as well as the modalities of its development. in EPS
in the Algerian school context. Fifteen (15) PSE teachers from the 1st and 2nd cycle of
secondary (middle and high schools) participated in the study. Two data collection
techniques (the individual interview and the focus group) were used. The collected
corpus was analyzed according to the strategy of content analysis. Several results have
emerged from the research, among others: a) the curriculum is favorable to the notion
of critical thinking, b) the PSE curriculum is unfavorable to the notion of critical
thinking, c) there is influence the culture of the country (religion, the impact of gender,
customs and traditions) on the critical thinking of teachers and students, d) the cultural
environment (family, school, Algerian society) does not motivate development and / or
to the expression of a critical thought of the pupils, e) the conception of the EPS in the
Algerian society is seen as a discipline of fun, release and a secondary subject
Lieu culturel: un nouvel espace hybride Projet d’institution culturelle de diffusion et création pour les arts et la culture issue de l’hybridité franco-ontarienne
No full textLa francophonie canadienne, plus minoritaire que jamais, fait
face à de nombreux défis, tels qu’un avenir démographique
précaire et une perception d’identité fragilisée. Cette thèse
s’intéresse aux communautés franco-ontariennes, couramment
définies par une dualité linguistique et identitaire, générant
une hybridité culturelle, et explore ces concepts pour conclure
que l’hybridité est un atout unique à célébrer. Malgré tout, la
vitalité culturelle demeure précaire et la thèse s’intéresse donc
au potentiel d’une institution culturelle de diffusion et création
pour les arts et la culture pour célébrer, mais aussi dynamiser
l’hybridité culturelle d’une communauté francophone du
Nord-Est de l’Ontario. Une étude des différentes catégories
d’institutions culturelles stimulant la vitalité culturelle a
permis de définir le programme de l’institution, alors que
l’étude de l’histoire de Timmins, la ville accueillant le projet, a
permis d’identifier des marqueurs identitaires qui sont intégrés
à l’architecture afin d’ancrer le bâtiment dans son contexte,
célébrant l’identité de la communauté
"mosque" : shaping an architecture for the Muslim community of Northern Ontario
No full textThe role of a mosque in a minority
community, such as Northern Ontario, shifts from
its common role as solely a sacred place. There is
a consistent conflict that arises in western mosque
architecture: western mosques have become isolated
entities, located on the edges of cities and disconnected
from the communities that need them.01 In a minority
community the mosque must transcend the singular
program of prayer/religious practice and begin to serve
the secular along with the religious communities.02
This integration of community allows the mosque to
become a more integral part of the society as a whole.
Beyond the traditional roles they play in Muslim
majority communities, mosques become places for
both secular and non-secular programs through secular
spaces, such as, educational, cultural, art, and social
places.
Thus, this thesis will re-investigate western
contemporary mosques to understand how these
mosques could be able to provide for both the secular
and religious communities in Northern Ontariowhile still maintaining the sacred qualities that make
these spaces unique.
The thesis will tackle this issue
through three different categories of communities:
non-Muslim community, current community, and new
community. In this discussion, the three categories
represent the following demographics. Non-Muslim
communities refer to the secular society of the
region along with the indigenous population. Current
community is the first, second, and third generation
of Muslims who are currently navigating their own
identities and require a place to learn and grow in a
healthy environment. New community refers to the
population of people who have recently immigrated
or been displaced to the region; for example refugees,
or converted Muslims, the communities who are in
transition and need help establishing their new lives.
The key to this thesis is taking
agency in the approach as a first generation MuslimCanadian and tackling tackling the issues through this
particular perspectiv
The effects of dietary ingestion of nickel recovery slag as a grit source on avian bone
No full textNickel recovery slag has been ubiquitously deposited in the environment of the Sudbury, Ontario basin giving merit to a study of the impact of this foreign material on wildlife in the area. In this work, the effects of ingestion of this largely metallic grit source on the bone health of Columbia Livia Domestica pigeons was measured.
This was accomplished by controlling the diets of two groups of birds, one given
exclusively limestone grit, the second given exclusively slag as a grit source. After
one year of this controlled diet, the subjects were euthanized and their tibiotarsi
were subsequently harvested for testing. Tests performed on the tibiotarsi including
breaking strength, Young’s modulus, cortical thickness, density, bone mineral
density, and mass spectrometry with a focus on iron and calcium concentrations.
Additionally, conventional micrographs and scanning electron micrographs with
accompanying energy dispersive spectrometry were collected. Our analyses of the
results are consistent with degraded bone physiology in the slag‐fed group
compared to the control birds
Immune - modulatory effects of sidr honey: implications for anti-proliferative effects on cancer cells
No full textHoney has become popular as a potential treatment for several ailments, including many cancers.
Being a natural product, honey is often considered to be a safe and inexpensive adjunct or
sometimes even an alternative to the currently available cancer treatments (including
chemotherapy and radiotherapy) that have adverse side effects. Honeys from different parts of
the world have shown anti-proliferative, immune-modulatory, and anti-inflammatory actions.
Yemeni Sidr Honey (YSH) is a world-renowned honey whose anti-inflammatory activity
suggests the possibility of underlying anti-cancer and/or immune-modulatory actions. Our
studies have shown that treatment with 1% YSH is able to inhibit proliferation, and induce
apoptosis in breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines
(Hela). We also showed that THP-1 monocyte-like cells differentiated by treatment with phorbol
ester and then treated with YSH affected their polarization into M1 or M2 macrophages:
treatment with YSH for 24 h, enhanced the expression of the M1 phenotype while treatment of
the macrophages with LPS and YSH for 48 h increased the level of M2 markers of
differentiation. Further, co-culture of the M1 differentiated macrophages with breast cancer cells
showed that treatment of the macrophages with YSH decreased tumour cell growth and
increased apoptosis. These results suggest treatment with YSH is able to impact cancer via two
separate mechanisms: direct impacts on cancer cell survival and activation of anti-tumour
immune system (monocyte) activation
Exploring the needs of transgender peoples living in Northern Ontario through service providers' experiences
No full textThe experiences of people who identify as transgender have begun to be discussed in
some service provider areas such as mental health services, hospitals, and educational facilities.
Transgender individuals would benefit from services being implemented that specifically pertain
to their needs, for example, specialized counselling, support groups, and safe spaces. There
appears to be a required need for an increase in community understanding, practitioner
understanding, and appropriate and available services. With the transgender population
increasing and individuals identifying earlier in life, it is crucial that practitioners have
appropriate training and education to work with this population. It is also important that
communities have the resources and services required by the transgender population. This study
explored health and social service provider perspectives on supports for transgender people in
Timmins Ontario. Ten service providers participated in semi-structured interviews. A qualitative
thematic analysis was completed and revealed three main themes: (1) Social work approaches
that are present and needed; (2) Services that have been developed and services still needed; (3)
Strengths of the community. The study concludes that social work approaches should be paired
with gender theory when working with transgender people, Timmins Ontario requires more
transgender specific services to meet the needs of the transgender community, and that service
providers would benefit from additional specialized training. It is recommended that service
providers advocate for specific transgender service development, additional training and
education, and become familiar with using gender theory in practice.Master of Social Work (MSW
The clinic: paradigm shifts in urban design and stigma free healthcare
No full textThis thesis examines the link between architecture and queer spaces, exploring how standardized clinical facilities can be transgressed and queered to suit the needs of a comunity largely left out of normative healthcare. 2SLGTBQ co, mmunities2SLGBTQ people cannot be defined by their physical attributes; therefore the community is often left to be defined by the spaces they frequent. Queer people have appropriated
spaces, and negotiated social structures to fulfil their needs as individuals as well as members
of a wider queer community. The thesis examines the history of queer people and the village in Toronto, Ontario through a lense focusing on healthcare and wellbeing. The Toronto Church and Wellesley Village has been the site of raids, protests, rallies, stigmatization, and prejudice. Murals are celebrated and cover old and new
structures in the village depicting the controversial past and mark the importance of these events to the development of queer Toronto. Expanding on these murals, and drawing on their history,
intentions and design this thesis proposal proposes a queer architecture and urban comple