6810 research outputs found
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Nursing Students’ Attitudes and Preparedness for MAiD
Full text linkMedical assistance in dying (MAiD) also known as physician-assisted suicide in addition to euthanasia is on the rise with an increase in decriminalization of the practice(s) and enactment of practice-protected policies in many countries. Ethics and morals on the subject continue to be controversial in healthcare. As student nurses enter the field as clinicians, they may encounter a patient requesting MAiD. Studies from students in other countries where MAiD and/or euthanasia is practiced found that student nurses do not feel adequately prepared to navigate such situations. However, although MAiD has been legalized in a handful of states within the United States, there is a lack of research on the attitudes of student nurses in the U.S. toward MAiD & euthanasia and how prepared their nursing programs make them feel. This study aims to explore the attitudes and beliefs of student nurses in the U.S. on MAiD and euthanasia and what factors influence their standpoint on the topic. The proposed study would use a cross-sectional approach to gather quantitative and qualitative data by using a convenience sample of 200 students enrolled in Bachelor of Science in Nursing programs across California. It is hypothesized that students\u27 attitudes towards MAiD, PAS, and euthanasia are heavily influenced by morality and educational or clinical experiences. The findings of this study may precipitate the need for an additional nursing curriculum that incorporates MAiD, PAS, and euthanasia care
A Mind ful Diet: Analyzing Nursing Education on the MIND Diet for Early-Onset Alzheimer\u27s Disease
Full text linkEarly-Onset Alzheimer’s Disease (EOAD) is a rare form of Alzheimer’s Disease (AD) that makes up around 5% of AD cases. The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, a hybrid diet of the Mediterranean and DASH (dietary approaches to stop hypertension) is an approach that patients with EOAD can adapt to slow down the progression of cognitive decline. Current literature focuses on what the effects of the diet are more for AD and not EOAD specifically, where there is less of an established baseline of nurse knowledge. The lack of research about what nurses understand regarding providing education of the MIND diet to patients with EOAD can be addressed further. Purpose: This research proposal aims to fill the gap of determining the knowledge baseline of the MIND diet from nurses who have or had experience in caring for patients with Early-Onset Alzheimer’s Disease in order to aid in the contribution for further studies creating educational modules targeting knowledge deficits. Method: A quantitative descriptive survey questionnaire about the MIND diet will be conducted on nurses with experience in caring for patients with EOAD
The Sound of Survival: The Effect of Personalized Music Selection on CPR Performance and Anxiety Levels
Full text linkhttps://scholar.dominican.edu/nursing-student-research-posters/1158/thumbnail.jp
Treatment Safety in Pediatric Atopic Dermatitis
Full text linkPurpose
The purpose of this study is to compare the safety and long-term effects of topical calcineurin inhibitors (TCIs) and topical corticosteroids (TCS) in pediatric patients diagnosed with atopic dermatitis (AD), and to compare the prescribed treatment use for 6 to 12 months. By providing evidence on prescribed topical treatments, their safety differences, and long-term effects, healthcare professionals can make informed decisions to minimize risks and choose the safest appropriate treatment for children. Method
This study will employ a quasi-experimental design, and participants aged 2-18 years will be selected from a clinic. Participants and their families will complete an initial baseline survey. Follow-up assessments will be conducted at 1, 3, 6, and 9 months of treatment to evaluate treatment safety and efficacy continuously. Following the intervention, data will be gathered through a final survey and various measurement tools. Results
If the findings are statistically significant, then it will prove the hypothesis that topical calcineurin inhibitors have fewer long-term effects and are safer to use compared to topical corticosteroids in pediatric patients with atopic dermatitis. Conclusion
Many children continue to struggle through their early years as parents are hesitant to rely solely on topical steroids due to their numerous risks. The lack of knowledge for parents and families on AD treatment creates a gap for education on alternative therapies such as topical calcineurin inhibitors (TCIs)
Virginia Woolf and The Lesbian Literary Tradition
Full text linkModernist English authors, such as Virginia Woolf in her novel Orlando: A Biography, built upon a pre-existing and long tradition of underground lesbian literature dating back to Sappho in Ancient Greece. Before Woolf, female writers of the 19th century continued this tradition by establishing the literary trope of the “Victorian Romantic Female Friendship,” which would later take on different shapes and connotations with discoveries made in the early 1900s related to sexology and homosexual inversion. These discoveries would lead writers to code their work in the hopes of avoiding censorship and government punishment. Writers such as Virginia Woolf, Elizabeth Gaskell, and Djuna Barnes all used different creative techniques to avoid censorship while also telling queer stories. Works by these authors are integral to the lesbian literary tradition and have created a unique style incorporating imaginative elements to tell these stories in the mainstream. Since their publications, the works by these authors have caused a cultural stir especially for queer subcultures in women’s colleges, all-female boarding houses, and other same-sex communities throughout America and England. Authors like Virginia Woolf experienced a resurgence in cultural relevance in the 1970s during the gay liberation movement. Feminist scholars such as Bonnie Zimmerman, Lillian Faderman, and several others were fundamental in legitimizing lesbian studies and literature in the academic sphere. Through the use of comparative literary analysis, historiographic research, and historical contextualization using primary and secondary sources, this research aims to explain the evolution of sapphic dynamics within the historical context of these novels’ authorship: Cranford by Elizabeth Gaskell, Mrs. Dalloway by Virginia Woolf, Orlando by Virginia Woolf, and Nightwood by Djuna Barnes
Exploring Age-Related Musculoskeletal Decline and Osteoarthritis: Novel Analysis of Senescent Chondrocytes and Spatial Proteomics Study on Bone Remodeling
No full textCellular senescence is believed to be a driver in the development of osteoarthritis (OA). This cellular state leads to alterations in features such as increased cell volume, flattening of the nucleus, and secretion of inflammatory proteins known as the secretory-associated senescent phenotype (SASP). Articular chondrocytes are the cells that maintain cartilage in the knee, and with age, they can become senescent, leading to the development of OA. Our lab has previously developed a novel tool to assess and quantify senescence in vitro called fully automated senescence test (FAST). The overall goals of this study were as follows: (1) develop and characterize a senescent primary human chondrocyte model for high throughput screening; (2) determine the FAST’s ability to analyze senescence in senescent chondrocyte cells; (3) expand FAST’s capability to include the cell death assay, TUNEL; and (4) test a potential senolytic compound called Urolithin A. FAST was used to quantify the induction of senescence in chondrocytes and IMR90 cells with different inducers, including irradiation (IR), doxorubicin, and MIDAS (antimycin A with rotenone). Using these conditions, we successfully established TUNEL staining assessment as an addition to FAST. Senescence-induced cells were treated with Urolithin A to test for any senolytic capability. Higher doses of urolithin A in human chondrocytes appeared to enhance senescence signatures, whereas lower doses resulted in an increase in nuclear areas. FAST was optimized for IR-induced senescence. Here, we applied FAST to analyze MiDAS-induced senescence, which resulted in a marked increase in senescence signatures, demonstrating the successful incorporation of MiDAS into the FAST platform and TUNEL. This study used methods of automated fluorescence microscopy to assess different senescence inducers like IR, doxorubicin, and MiDAS. FAST could assess up to three stains in a single cell allowing for a comprehensive senescence evaluation. This study lays the foundation for a high-throughput senolytic screen in senescent human chondrocyte cells that could identify a potential therapeutic for osteoarthritis (OA).
The musculoskeletal system undergoes progressive decline with age, often leading to slower fracture repairs in older individuals. To investigate the molecular basis of this delay, we applied spatial proteomics through MALDI mass spectrometry to unfixed tibial fractures in young versus aged mice. Because MALDI workflows currently lack robust tools for unbiased protein-to-library matching, we developed a custom script to annotate spectra against a comprehensive reference database. Using this pipeline, we identified a suite of fracture-associated proteins, with type I collagen chains (COL1A1 and COL1A2) dominating the dataset. Analysis of their fibrillar states uncovered distinct assembly patterns between young and aged samples, implying age-related alterations in collagen organization. Additionally, we detected elevated levels of calreticulin in both young and fully healed bone, offering novel insights into the mechanisms that may underlie impaired bone remodeling in aged fractures
The Sound of Survival: The Effect of Personalized Music Selection on CPR Performance and Anxiety Levels
Full text linkThe connection between music and CPR has gained attention in recent media, yet there is limited research examining its effects on CPR performance, particularly with regard to anxiety levels. This study aims to evaluate the impact of personalized music selection on CPR performance and anxiety levels among first-time trainees. Specifically, the study will assess whether personalizing CPR training with music that aligns with the optimal chest compression rate enhances overall compression quality while simultaneously reducing anxiety in the rescuer. Using a randomized controlled trial design, CPR quality (rate, depth, and consistency) and anxiety levels will be measured. The sample will consist of 50 first-time CPR trainees, with the experimental group receiving personalized music during training and the control group receiving standard CPR training. CPR performance will be assessed using Laerdal’s Resusci Anne and the QCPR feedback system, while anxiety levels will be measured using the Likert Anxiety Scale before and after training. CPR performance and anxiety will be reassessed 6 months later without any music intervention, but using the same measurement tools. It is expected that personalized music will reduce anxiety and improve CPR performance (rate, depth, and consistency) compared to standard training. This research may contribute to increasing bystander CPR initiation during cardiac events outside of hospital settings, potentially improving survival outcomes
The Impact of Sleep Deprivation on Maternal Decision-Making and Risk-Taking Behavior
Full text linkPurpose
The purpose of this research proposal aims to explore the impact of sleep education in new mothers and their ability to manage sleep deprivation with interventions during the postpartum period.
Methods
This research proposal includes various methods to evaluate the effectiveness of sleep education and mental health screenings in new mothers. The baseline data for sleep quality, postpartum depression, and the new adaptation to motherhood will be collected using the Edinburgh Postnatal Depression Scale, actigraphy to monitor sleep patterns, and a conduction of cognitive functioning with the Mini-Mental State Examination. After interventions are put into place, follow up data will be collected at 1, 3, and 6 months to evaluate effectiveness.
Results
After sleep education is provided, the findings of this proposal will be expected to be statistically significant and support the hypothesis, demonstrating improvements in both sleep quality and maternal mental health status.
Conclusion
This proposal is expected to demonstrate that sleep education can play a role in improving sleep quality and mental health during the postpartum period. The results from this research are expected to demonstrate that the interventions help new mothers manage sleep deprivation and adapt to motherhood effectively
A Happy Medium?: Using Image Generators to Explore Solution-Focused Art Therapy’s Miracle Question
Full text linkThis mixed methods, randomized, single-session study tested whether integrating text-to-image generations into Solution-Focused Brief Art Therapy alters therapeutic rapport and short-term outcomes relative to traditional artmaking materials. Participants were assigned by coin flip to create using either a text-to-image generator or convention media (23 per group), completing immediate and three-day follow-ups. Alliance was measured using DREAM (Dimensions of Regard, Empathy, and Authenticity Metric), and problems were rated pre/post; groups did not differ significantly on DREAM total or facets, and both modalities produced reliable pre-to-post reductions in problem severity. At the same time, process differences were pronounced: the AI condition showed substantially higher medium resistance and markedly impaired multitasking during artmaking. Multitasking ability followed an inverted-U relation with distress reduction—moderate ability corresponded to the largest gains—and correlated positively with several DREAM dimensions (overall rapport, unconditional positive regard, empathic understanding). Together, these findings indicate that text-to-image generation can materially shift the creative process without degrading immediate alliance or symptomatic improvement in this brief format, suggesting cautious, evidence-led integration: to use AI when it demonstrably supports access, engagement, or fit with therapeutic goals, and to revert to tactile media when attentional load or process disruption threatens rapport or efficacy
Restorative Justice Initiatives in Marin County: Mitigating the Impacts of the School-to-Prison Pipeline on Youth
Full text linkMy senior thesis project delves into Restorative Justice\u27s role in addressing the school-to-prison pipeline in Marin County. Restorative Justice prioritizes repairing the harm caused by crime to individuals, relationships, and communities, advocating for offenders to take responsibility and make amends rather than solely facing punishment (Restorative Justice Exchange, 2022). My capstone aims to pinpoint factors driving student exclusion from schools and subsequent entanglement in the legal system while highlighting how restorative approaches can prevent such outcomes. Additionally, it discusses the benefits of removing police officers from schools and reducing reliance on law enforcement within educational settings. My research will use a community-engaged methodology; I want to listen to and understand the community stakeholder perspectives through interviews and engagement. Their perspectives are crucial because of their direct involvement in the Restorative Justice practices currently happening in Marin County