TIET Digital Repository Thapar Institute of Engineering & Technology
Not a member yet
6889 research outputs found
Sort by
Synthesis of Bis-coumarin Based Probe for the Detection of Serum Albumin
No full textBis-coumarin based probe has been synthesized which provides insight into the differential response on interaction with different bioanalytes. Photophysical studies has been performed to detect the bioanalytes and it has been observed that probe 5 selectively detects the serum albumin i.e., BSA and HSA with more sensitivity towards HSA. On gradual addition of HSA (62 M), 74% quenching has been obtained while in case of BSA (62 M) 60% quenching was observed. Further, binding constants have been calculated to demonstrate the effective binding between the synthesized probe 5 and the serum albumins and found to be 7.4 x 105 M' in case of HSA while 6.7 × 105 M' for BSA. Moreover, site marker study has also been carried out to find out the specific binding site of the probe 5 in HSA which revealed the warfarin like binding of the probe 5 i.e., Suldow's site I
Role of Anxiety in Emotional Priming on Dual Mechanism of Control
No full textCognitive control enables the modulation of action and thought in response to internal
objectives, promoting adaptive functioning in complex situations. The Dual Mechanisms of
Control (DMC) theory argues that cognitive control is divided into proactive (goal-directed)
and reactive (stimulus-driven) modes that help to flexibly mold their actions depending on
the requirements of the given task. The current research examines the interaction between the
influence of emotional priming (anger, sadness, happiness, and neutral states) and trait
anxiety (high and low) on dual mechanisms of control through a spatial Stroop paradigm. Using the State-Trait Anxiety Inventory (STAI) to differentiate anxiety levels and examine
the interference effects with varying proportions of congruence to address dual mechanisms
of control under varying emotional conditions, this research seeks intervention to address
important gaps in cognitive-affective control literature
TLP-vfTLP Testing for ESD Models
No full textElectrostatic Discharge (ESD) protection is critical for ensuring the reliability and longevity of electronic
components. The RC clamp, consisting of a resistor (R) and a capacitor (C), is a widely used circuit for
mitigating the effects of ESD events. This abstract presents an overview of Transmission Line Pulse (TLP)
and Very-Fast Transmission Line Pulse (VF-TLP) testing methodologies applied to RC clamps to evaluate
their ESD protection performance.
TLP testing is employed to simulate ESD events and characterize the response of the RC clamp by applying
controlled, high-current pulses. This method provides valuable insights into the clamp's current-voltage (I-V)
characteristics, enabling the assessment of its clamping voltage, trigger voltage, and holding voltage. TLP
testing helps in identifying the clamp's effectiveness in limiting the peak current and voltage during an ESD
event, thereby ensuring the protection of sensitive electronic components.
VF-TLP testing, on the other hand, offers a more detailed analysis by applying extremely fast pulses with
rise times in the sub-nanosecond range. This testing method is crucial for understanding the RC clamp's
behavior under rapid transient conditions, which closely resemble real-world ESD events. VF-TLP testing
allows for the evaluation of the clamp's dynamic response, including its ability to absorb and dissipate
energy within very short time frames. This is particularly important for assessing the clamp's performance in
high-speed and high- frequency applications.
The combined use of TLP and VF-TLP testing provides a comprehensive evaluation of the RC clamp's ESD
protection capabilities. The results from these tests help in optimizing the design of the RC clamp, ensuring
that it effectively mitigates ESD-induced damage and enhances the overall reliability of electronic devices.
By understanding the RC clamp's performance under various pulse conditions, designers can make informed
decisions to improve ESD protection strategies in modern electronic systems.
In conclusion, TLP and VF-TLP testing are essential methodologies for characterizing the ESD protection
performance of RC clamps. These tests provide critical insights into the clamp's ability to limit peak currents
and voltages, absorb transient energy, and protect sensitive components from ESD damage. The findings
from TLP and VF-TLP testing contribute to the development of more robust and reliable ESD protection
solutions in the electronics industry
Experimental investigation and statistical analysis of 3D printed electrically conductive ABS
No full textThis study explores the design, fabrication, and performance evaluation of ABS test specimens, focusing on optimizing their mechanical and electrical properties for practical applications. The process began with developing a CAD model, which served as the basis for systematically manufacturing the test samples. Initial mechanical testing validated the fabrication approach, confirming its reliability. Furthermore, this work presents a detailed experimental and statistical investigation into the mechanical and electrical properties of 3D-printed conductive ABS parts manufactured using the Fused Deposition Modeling (FDM) process. The study aimed to optimize process parameters to enhance both tensile and compressive strength while maintaining adequate electrical conductivity for potential multifunctional applications.
In the tensile strength analysis, key parameters including printing speed (PS), layer height (LH), temperature (TEMP), and infill density (ID) were varied systematically. The results showed that lower printing speeds (40 mm/s) and higher infill densities (up to 100%) contributed significantly to improved tensile performance. The highest tensile strength recorded during experimental trials was 44.56 MPa, closely matching the model prediction of 42.56 ± 3.00 MPa, validating the accuracy of the statistical model (R² = 97.94%).
For compressive strength, the optimized settings included a layer height of 0.5 mm, a temperature of 245°C, and 100% infill. The best experimental compressive strength achieved was 65.89 MPa, with a model-predicted value of 65.64 ± 3.16 MPa, again confirming strong model reliability (R² = 98.39%).
To ensure the robustness of the predictive models, confirmation experiments were performed using different parameter combinations. The deviation between model predictions and actual test results remained within an acceptable range (±3MPa), demonstrating high reproducibility and precision of the optimization framework.
In addition to mechanical evaluation, the electrical conductivity of the printed samples was measured using an LCR meter (Fluke PM 6306). The conductivity achieved was in the order of 10⁻³ S/mm, indicating that the material maintained a satisfactory level of electrical performance even under mechanically optimized conditions.
Overall, the study demonstrates that through careful selection and optimization of process parameters, it is possible to manufacture 3D-printed ABS parts that are both structurally strong and electrically conductive. These findings provide a practical and statistically validated framework for developing multifunctional components suitable for use in smart enclosures, embedded electronics, and lightweight structural applications
Assesment of Seismic Parameters in Reinforced Concrete Tall Structures Utilizing Shear Cores, Shear Walls and Shear Cores with Outriggers
No full textThe increasing demand for vertical development in urban areas has led to a growing need for tall buildings that are both efficient and safe under lateral loads such as wind and earthquakes. As buildings rise in height, their vulnerability to lateral forces becomes a significant concern in structural design. Engineers adopt different structural systems to strengthen buildings and limit lateral movement during seismic or wind events. This study focuses on evaluating and comparing the seismic performance of a G+30 reinforced concrete (RC) building using different structural configurations, including a moment-resisting frame, corner shear walls, a central shear core, and outrigger systems.
The building models were developed in ETABS 2021 and analysed under seismic Zone IV conditions following IS 1893 (Part 1): 2016. Two methods-Equivalent Static Analysis method and Response Spectrum Analysis method were used to examine key performance parameters such as storey displacement, base shear, inter-storey drift, and storey shear. Five structural cases were studied to observe how different arrangements affect the distribution of seismic forces and the overall behavior of the structure.
Among all configurations, the model with a central shear core combined with double outriggers exhibited the most favorable results, showing significant reductions in lateral displacement and storey shear. The results clearly indicate that the inclusion of outriggers enhances lateral stiffness and improves seismic performance, making them a reliable choice for high-rise structures situated in earthquake-prone areas. This comparative study aims to assist structural designers in selecting suitable lateral systems during the planning and analysis of tall RC building
Transition Metal-Catalyzed C-H Functionalization for the Synthesis of Bioactive Heterocycles
No full textIn this thesis we have used directing group assisted, transition metal catalyzed C-H activation, enabling the regioselective functionalization of bioactive molecules. This approach allows for the direct functionalization of multiple C-H bonds in a single reaction through C-H bond activation. We were able to achieve dual C-H bond functionalization of naphthalimide and sequential C-H/ N-H alkene annulation of phenanthroimidazoles. The C2-alkenylation of indoles was achieved by cyclic amide of quinazolinone moiety as a directing group. We developed a library of C-H functionalized bioactive compounds and assessed their potential as anticancer agents. These compounds show promising applications in both therapeutics and materials science
Self-healing of Cementitious Structures through Biomineralisation by Using Fungal System
No full textMicro-cracks in cement-based materials significantly reduce their durability by allowing
moisture and aggressive agents to penetrate, eventually compromising structural performance.
This research explores the use of urease-positive fungal strains to enable autonomous crack
healing in concrete via microbial-induced calcium carbonate precipitation (MICP). Two healing
strategies were employed: direct injection of fungal hyphae into cracks and a novel approach
where fungal spores were incorporated with fly ash to act as a carrier and filler medium. After
introducing artificial cracks in mortar specimens, the fungal healing agents were applied,
followed by nutrient spraying to encourage fungal proliferation and calcite precipitation within
the cracks. The healing performance was evaluated through compressive strength tests,
enzymatic urease activity measurement, calcium ion quantification, and Scanning Electron
Microscopy (SEM) analysis. The specimens treated with spore-fly ash composites showed
superior crack sealing efficiency and maximum strength regain, attributed to the combined
pozzolanic reaction and biologically driven mineral deposition. This study validates fungal
biomineralization as a viable, eco-friendly self-healing technique, offering a sustainable
alternative to traditional repair methods for enhancing the longevity and durability of
cementitious infrastructure
Efficacy of Compliant Tuned Liquid Column Dampers (CTLCD) for Seismic Vibration Control
No full textThis thesis presents an experimental investigation into the seismic response mitigation of a
three-story scaled building model using a Compliant Tuned Liquid Column Damper (CTLCD).
The study begins with a comprehensive literature review covering the development and
performance of passive vibration control devices, particularly Tuned Liquid Column Dampers
(TLCDs), and their evolution into more advanced forms such as Tuned Liquid Column Ball
Dampers (TLCBDs) and Compliant TLCDs. The review establishes the effectiveness of fluidbased damping systems and highlights the need for further exploration of compliant designs in
short-period structures.
To evaluate the performance of the CTLCD, a series of shake table experiments were
conducted using 43 ground motion records encompassing a wide range of seismic
characteristics. Acceleration and displacement responses were recorded at each floor under
both uncontrolled and controlled conditions. The structural responses were analyzed in terms
of peak and Root Mean Square (RMS) values to capture both instantaneous and sustained
motion. The results demonstrate that the CTLCD effectively reduces RMS responses,
particularly at the upper stories where dynamic amplification is more significant. Although
peak response reduction varied depending on the ground motion, substantial energy dissipation
and control of prolonged vibrations were observed.
Correlation analyses and control efficiency calculations further revealed the CTLCD's
nonlinear damping behavior and its greater influence on RMS reduction than on peak
suppression. Time history plots confirmed reductions in amplitude and vibration duration,
especially at the top floor. These findings affirm the CTLCD’s potential as a passive control
strategy for enhancing the seismic resilience of flexible, multi-story buildings and provide a
foundation for future advancements in fluid-based damping technologies