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    Transidentification in Adolescents and Young Adults: Understanding Parental Concerns to Improve Psychological Support for Families

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    Capucine Lamoureux, psychologue, ParisInternational audienceThis study explores the experiences and perceptions of parents of adolescents and young adults who identify as transgender, particularly focusing on the anxiety and ambivalence that some parents experience regarding their child’s disclosure of a transgender identity. While existing research on transidentity among minors has addressed challenges within family dynamics, it has not deeply examined the underlying reasons for parental hesitation in supporting their child’s transition. To fill this gap, we collected and analyzed letters from 60 parents using the Interpretative Phenomenological Analysis method. The findings reveal that parents often struggle with profound ambivalence, balancing fears about the potential consequences of their child’s transition with a desire to provide support. The disclosure of a transgender identity frequently challenges parent–child communication, resulting in perceived disconnects and concerns about the child’s mental health. Parents actively sought guidance from healthcare professionals but often felt disappointed by consultations they perceived as lacking thoroughness. Based on these findings, we recommend adopting an exploratory and psychotherapeutic approach in healthcare, fostering individualized and supportive care for both families and transgender youth, in contrast to standardized, protocol-driven consultations that may overlook the complexity of family dynamics and psychological factors

    Les outils numériques à destination des élèves porteurs d’un trouble du développement intellectuel

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    Productions des groupes thématiques numériques (Direction du numérique pour l’éducation du Ministère de l'Éducation nationale, de l’Enseignement supérieur et de la Recherche)Ce bulletin de veille est rédigé dans le cadre du groupe de travail GTnum #EBEP (2021-2024), intitulé « Les apports des technologies numériques au développement et aux apprentissages des élèves à besoins éducatifs particuliers », porté par le 2LPN (Université de Lorraine) et le C2S (Université de Reims-Champagne-Ardenne). Ce bulletin présente la manière dont les outils numériques peuvent soutenir le développement des compétences cognitives, motrices, socio-émotionnelles et scolaires des élèves présentant un trouble du développement intellectue

    A Multi-Technique Machine Learning Workflow for Optimizing the Manufacturing Process of Functional Layers in Electrochemical Energy Devices

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    International audienceIn this presentation we will share our latest developments revolving around the utilization of Artificial Intelligence/Machine Learning techniques to optimize the manufacturing process of functional layers in lithium ion batteries (electrodes) and polymer electrolyte membrane fuel cells (gas diffusion layers -GDL-). We have used several machine learning techniques (including unsupervised, supervised and deep learning techniques) to predict the influence of manufacturing process parameters (e.g. slurry formulation, drying temperature, electrode calendering degree, GDL fiber diameter) on the properties of the functional layers (e.g. conductivity, tortuosity factor, porosity). We have also applied deep learning techniques in order to derive surrogate models mimicking the behavior of physics-based numerical models simulating the manufacturing process of the electrodes. The so-derived machine learning models are then used in combination with optimization algorithms in order to perform inverse design of the manufacturing processes, i.e. predicting which manufacturing parameters we need to adopt in order to maximize and/or minimize given properties. In this presentation, we review these developments, including the different workflows that we designed and discuss our manufacturing digitalization vision towards accelerated design of functional layers for electrochemical energy device applications. We believe that this approach gives the promise to reduce costs and save time in the industrialization of these devices towards a more sustainable world

    RGB-D versus omnidirectional visual SLAM in humanoid robot positioning

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    International audienceVisual Simultaneous Localization and Mapping (V-SLAM) with an color plus Depth (RGB-D) camera is the gold standard to help correcting humanoid robots’ drift while walking toward a goal pose indoors. But, the bounded range and Field of View (FoV) of these cameras constrain the use cases for humanoids to few changes in the environment. At the same time, compact omnidirectional cameras capable of a 360° FoV are spreading quickly at low cost, offering more possibilities to the V-SLAM system to observe reliable features whichever the robot orientation. Thus, this paper investigates the V-SLAM with a 360° camera versus an RGB-D one in the humanoid head for correcting the walking drift of a baseline walking controller over several meters. The Baseline Biped Positioning hence made is evaluated regarding final pose accuracy improvement and robustness to environmental changes by leveraging multiple sets of real experiments on a 1.8 m tall humanoid robot

    Édition d'une lettre chiffrée de Charles Quint à Jean de Saint-Mauris (1547)

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    Édition de sourcesConservée de manière isolée à la Bibliothèque municipale de Nancy, une lettre chiffrée adressée en février 1547 par Charles Quint à son ambassadeur auprès du roi de France, Jean de Saint-Mauris, a fait l'objet en 2022 d'une cryptanalyse. À la suite de celle-ci, un travail de recherche (autres exemplaires de la lettre, autres lettres chiffrées) et d'édition a été mené afin de replacer cette lettre dans l'environnement épistolaire et cryptographique large qui était le sien. Cette édition permet ainsi de disposer, outre d'un accès complet au texte de la lettre, d'un aperçu des pratiques cryptographiques impériales du milieu du XVIe siècle

    Quantitative Evaluation of Low-Frequency Oscillation in Blood and CSF Flow and its Changes from Eye Open to Eye Closed

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    International audienceMotivation: Low-frequency oscillations (LFO) are a key driver of brain waste clearance, yet their role in CSF has only been qualitatively assessed using fMRI, lacking quantitative evaluation. Goal(s): To quantitatively evaluate LFO in blood and CSF flows and study changes with drowsiness. Approach: Arterial, venous, and CSF flow at the cervical level (C2/C3) were measured using real-time phase-contrast MRI, with measurements once with the eye open and once after a 30-minute eye closure. Band power from LFO, respiration, and cardiac pulsations were analyzed. Results: LFO shows an increase from awake to drowsy in all fluid compartments, despite contributing small to overall oscillations. Impact: Cervical CSF flow shows LFO at 3%, below respiration (13%) and cardiac (84%), contrasting with LFO>cardiac at the fourth ventricle in fMRI. The consistent LFO increase from alert to drowsy suggests a role in enhancing fluid clearance during sleep

    Minoxidil and nebivolol restore aortic elastic fiber homeostasis in diabetic mice via potassium channel activation

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    International audienceBackground: Diabetic patients experience a significant reduction in life expectancy, primarily due to early cardiovascular complications. A key feature is the premature degradation of elastic fibers (EFs), contributing to vascular stiffness.Objective: This study evaluates the capacity of two antihypertensive agents, minoxidil (a KATP channel opener) and nebivolol (a β-blocker with KATP activity), to restore EF homeostasis and arterial elasticity in diabetic mice. Methods Mice are treated with two antihypertensive agents: minoxidil (an ATP-sensitive potassium (KATP) channel opener) or nebivolol (a β-blocker also active on KATP channels). The degree of wear and functionality of EF are assessed after these treatments. We complement this analysis by identifying molecular actors from smooth muscle cell cultures.Results: Our data show that by applying these antihypertensive agents in cultured vascular smooth muscle cells in vitro and in diabetic mice, we efficiently stimulate elastogenesis and inhibit elastolysis. Therefore, treatments restore functional EFs and limit their degradation. This brings blood pressure values of diseased mice close to normal ones (as in unaffected mice). Elastogenesis pathway stimulation and elastolysis inhibition are induced by the opening of sensitive KATP channels and the regulation of the forkhead box transcription factor (FOXO1).Conclusion: Minoxidil and nebivolol restore EF integrity and limit vascular aging in diabetic mice via K+ channel opening and FOXO1 repression. These findings highlight potassium channel–FOXO1 signaling as a therapeutic axis to counteract diabetic vascular complications

    Investigating the feasibility of helium OPM MEG in Amiens

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