Portail HAL de l'Université Picardie Jules Verne
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« Refonte des savoirs et reconstruction du sens dans les introductions de Cristoforo Landino à l’œuvre de Virgile »
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Diffuser l’anarchisme par la fiction : La Chasse aux loups (dernière partie et épilogue) de Louise Michel
No full textInternational audienceCet article expose les idées que Louise Michel souhaite faire passer par la fiction. Dans ce passage final du roman, elle développe l’image d’une grève générale qui débouche en révolution réussie. Elle y présente un anarchisme solidariste, point de rencontre entre l’anarchisme politique développé en première partie du roman et l’anarchisme social évoqué dans la deuxième partie
DEM-Based Modeling of Thermo-Mechanical Stresses and Fracture in Thermal Barrier Coatings
No full textInternational audienceDEM-Based Modeling of Thermo-Mechanical Stresses and Fracture in Thermal Barrier Coating
Interobserver reliability of the DESH score in idiopathic chronic hydrocephalus
No full textInternational audienceIntroductionidiopathic chronic hydrocephalus (iCH) is underdiagnosed in older adults. The diagnosis of iCH is important because effective surgical treatment is available. Indeed, iCH is the only curable dementia. The disproportionately enlarged subarachnoid space hydrocephalus (DESH) score was recently developed on the basis of morphologic MRI data, as a guide to the diagnosis of iCH in adults.Patients and methodIn a population of 68 patients having undergone placement of a ventriculoperitoneal shunt, the preoperative DESH score was calculated retrospectively by a senior neurosurgeon and a neurosurgery resident. To analyze inter-observer variability, the results obtained for each patient were compared. We calculated sensitivity, specificity, positive and negative predictive values of the DESH score.ResultsDESH score of 7 or more present the best diagnostic performance (sensitivity: 83%, specificity: 40%, positive predictive value: 89%, negative predictive value: 29%). The interobserver reliability of the DESH score was excellent, with an intraclass correlation coefficient of 0.936. Similarly, the levels of interobserver agreement for each individual item were fair (for Sylvian fissure dilatation, local focal sulci dilatation, and tight high convexity) to excellent (for the callosal angle).ConclusionThe DESH score is a reliable score obtained by studying brain MRI and radiographic datasets. The score’s excellent reliability means that it can be included in the routine diagnosis of iCH
Comparative features and outcomes of cardiogenic shock in patients with and without prior resuscitated shockable cardiac arrest: Insight from the FRENSHOCK multicenter prospective registry
No full textInternational audienceAim: Differences between cardiogenic shock (CS) with and without prior resuscitated cardiac arrest (CA) remain largely unexplored. We hypothesized that patients who experience shockable CA followed by CS are likely to have worse outcomes compared to CS without prior CA.Methods: FRENSHOCK is a prospective multicenter observational registry conducted in French critical care units in 2016, which included CS from various etiologies. Patients admitted after resuscitation of a CA were included if they fulfilled previously defined CS criteria. Non-shockable rhythms at the time of medical intervention were considered exclusion criteria and were not recorded in the registry.Results: Among the 771 enrolled patients (mean age 65.7 ± 14.9 years; 71.5 % male), 79 (10.2 %) had a resuscitated shockable cardiac arrest just before inclusion. Shockable CA patients had more respiratory support (78.5 % vs. 33.2 %, p < 0.001), more mechanical circulatory support (35.4 % vs. 16.5 %, p < 0.001), more coronary angiography performed (76 % vs. 48.8 %, p < 0.001), finding more mono-troncular lesions (39 % vs. 16.9 %, p < 0.001). Thirty-day and one-year survival were similar between groups. Among 30-day survivors, CS with an initial shockable CA exhibited significantly improved long-term survival compared to CS without prior resuscitated CA.Conclusion: In a cohort of patients with cardiogenic shock from various etiologies, approximately 10% had experienced prior resuscitation following a cardiac arrest with shockable rhythms. Our findings suggest that selected cardiac arrest with a shockable rhythm leading to cardiogenic shock does not inherently confer a worse prognosis compared to other causes of cardiogenic shock
Maximum Satisfiability Formulations for Nonlinear Integer Programming
No full textInternational audienceThis paper introduces novel Maximum Satisfiability (MaxSAT) formulations for the Nonlinear Integer Programming (NLIP) problems with discrete polynomial functions. We develop a generic framework based on three established integer encoding techniques from the literature. Our approach treats each polynomial term as an atomic unit and demonstrates how it can be efficiently encoded through compact representations of integer assignments. Additionally, we present two distinct decomposition methods based on the degrees of polynomial terms. This work lays a foundation for future research and has the potential to extend the applicability of modern MaxSAT solvers to a wider range of optimization problems
Professional Standards in Thoracic Ultrasound - EFSUMB Position Paper
No full textInternational audienceThis position paper of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) on professional standards in thoracic ultrasound is an adjunct to EFSUMB’s previously published professional standards in medical ultrasound – general aspects. The paper represents a position across the different medical professions within EFSUMB regarding optimal standards for the performing and reporting of thoracic ultrasound examinations by any professional ultrasound practitioner. It describes aspects that ensure procedure quality, effectiveness, efficiency, and sustainability in application of thoracic ultrasound. Recommendations are given related to safety and indication of thoracic ultrasound examinations, requirements for examination rooms, structured examination, systematic reporting of results, and management, communication and archiving of ultrasound data
Echocardiography guided management of atrial fibrillation
No full textInternational audienceBackground: The growing burden of atrial fibrillation (AF) experienced by the general population translates into an increased incidence in the intensive care setting, further aggravated by illness severity. New onset AF has been established as an independent mortality predictor. Cardiology management guidelines are based on major trials that included ambulatory patients with varying degrees of ventricular systolic and diastolic dysfunction, and with variable dependences of left ventricular filling on atrial systole. Emphasis is placed on rate control combined with anticoagulation therapy, along with careful consideration of limiting any myocardial depression by antiarrhythmic medication in patients who often already have some form of structural heart disease.Design: Narrative review Objectives: Critical care echocardiography (CCE) is well established as a widely available diagnostic and monitoring tool in haemodynamically unstable patients. It assists in identifying risk factors associated with arrhythmias, reveals parameters associated with arrhythmia chronicity, and guides therapy to facilitate a return to sinus rhythm. CCE helps guide the crucial management decision to seek either rhythm or rate control and, with rhythm control, monitors return of mechanical sinus rhythm with left atrial recovery post cardioversion. Echocardiography can also help when conflicting management goals are present, such as guideline-driven therapeutic anticoagulation in the intensive care patient that is at significant risk of bleeding.Results: This review seeks to assist intensive care practitioners managing patients with AF, with a focus on the many benefits CCE offers, blending specific intensive care medicine data to current cardiology guidelines on arrhythmia management in these severely ill patients
Valorization of Sugar Beet Byproducts into Oligogalacturonides with Protective Activity against Wheat Powdery Mildew
No full textInternational audienceThe shift toward sustainable agriculture emphasizes the need for eco-friendly biocontrol strategies. Oligogalacturonides (OGs), which are pectin-derived cell wall fragments, are promising plant defense inducers. This study evaluated two OGs mixtures, obtained from sugar beet byproducts, for their protective effect against Blumeria graminis f. sp. tritici (Bgt), the causal agent of wheat powdery mildew. OGs were generated by hydrolyzing pectins with two Arabidopsis thaliana polygalacturonases, ADPG2 and PGLR, expressed in Pichia pastoris. OGs-ADPG2 showed a degree of polymerization (DP) 1-10 and esterification (DE) 41%, while OGs-PGLR had DP 1-16 and DE 34.5%. Although neither inhibited Bgt spore germination directly, OGs-PGLR provided 31% preventive protection. Both OGs activated defense-related genes, but only OGs-PGLR induced lipoxygenase (9-LOX), initiating the octadecanoic pathway and oxylipin production. Overall, these results highlight the potential of OGs derived from sugar beet byproducts as sustainable alternatives to reduce phytochemical use in crop protection
Ovarian mature teratomas: Differences in management and outcomes in adolescents cared for by gynecologic and pediatric surgeons
No full textInternational audienceBackgroundOvarian mature teratomas (OMTs) are the most common benign ovarian tumors in pediatric patients. Management in adolescents can be performed by pediatric (PSs) or gynecologic surgeons (GSs). The aim of this study was to assess the differences in OMT management and the repercussions according to the risk of secondary events.DesignBased on a multicentric study, we compared patients aged 14 to 18 who underwent surgery for OMT between 2009 and 2022 from the French national pediatric database of OMTs with patients managed by GSs.ResultsIn total, 119 patients were included (80 by PSs, 39 by GSs). Differences between teams were noted: (i) tumor marker analysis is systematic by PSs (80%, n = 72) but rare by GSs (18%, n = 7) (P < 0.001), (ii) PSs mostly carried out a laparotomy (78%, n = 62), whereas GSs preferred laparoscopy (90%, n = 35) (P < 0.001), (iii) peroperative rupture was more frequent by GSs (56%, n = 22) than PSs (10%, n = 8) (P < 0.001), (iv) median duration of follow-up increased by PSs (20 months) versus 1 month by GSs (P = 0.001). Ten second events (13% by GSs [n = 5], 6% by PSs [n = 5]) occurred in nine patients, without significant differences (P = 0.151).ConclusionA notable difference exists in the management of OMTs between PSs and GSs in our study, GSs may overlook a malignant component in germ cell tumors in adolescents and the risk of metachronous recurrence, reported up to 10–20%. We recommend a compliance to SIOPE 2020 guidelines (Sessa et al., 2020) to avoid rupture of potential malignant tumor and to preserve fertility