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    Open Data from LIGO, Virgo, and KAGRA through the First Part of the Fourth Observing Run

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    International audienceLIGO, Virgo, and KAGRA form a network of gravitational-wave observatories. Data and analysis results from this network are made publicly available through the Gravitational Wave Open Science Center. This paper describes open data from this network, including the addition of data from the first part of the fourth observing run (O4a) and selected periods from the preceding engineering run, collected from May 2023 to January 2024. The public data set includes calibrated strain time series for each instrument, data from additional channels used for noise subtraction and detector characterization, and analysis data products from version 4.0 of the Gravitational-Wave Transient Catalog

    Stationnement intelligent sur la voirie : Étude des mises en oeuvre œuvre en ville et éclairages de responsables opérationnels

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    Smart solutions for on-street parking, which collect and leverage real-time information about on-street parking space availability to guide drivers or adjust policies, have attracted considerable attention in academia and in the corporate world, but comprehensive feedback on actual implementations was still missing. Here, we survey around 25 smart parking (SP) implementations in cities across the world using online sources. To get more candid insights, we complement this objective review with case studies centred around interviews that we conducted with practitioners from ten cities across continents (San Francisco, Saint Pete Beach, Penang, Douala, Soissons, Grand Paris Seine Ouest, Montpellier, Frauenfeld, Zurich, Perth).Summing up our observations, we underline the broad diversity of SP implementations in terms of contexts and scales, from 2-to-3-year small-scale pilot studies to large deployments that take centre stage in a city's mobility policy. Technological choices also vary widely, from the ground sensors used in pioneering deployments in the early 2010s and still in use, to static cameras (which cover more spaces per device), and to mobile cameras with automatic licence-plate recognition embarked in roaming cars, a more and more popular solution for parking control. Different attitudes to the role given to smartphone applications are also noticed. But, importantly, not only means, but also goals differ: facilitating parking control and enhancing revenue, or providing data for a curb-pricing strategy, or feeding live data into navigation algorithms to reduce parking search times. Unfortunately, their level of achievement is seldom gauged with robust metrics. Hardware durability issues are mentioned as causes of premature termination, particularly for `first-generation' ground sensors, but so, too, are fluctuating political will and changing priorities. Smaller-scale, geographically isolated implementations and pilots are particularly vulnerable to these fluctuations, to discontinued funding or defaulting start-ups, and to limited public awareness

    FANTASTIC CLINOFORMS AND WHERE TO FIND THEM? A DETAILED LOOK AT FLUVIAL TO DELTAIC DEPOSITS IN GALE'S LAYERED

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    International audienceCuriosity continues to explore the layered sulfate unit (LSu) of Gale crater as it ascends Mount Sharp. In mid-2025, the rover arrived in the orbitally-defined “boxwork” unit (Fig. 1). There, diagenetically-altered, fine-grained textures have been identified hinting at a probable lacustrine setting [1-2].By contrast, the walls of this valley, and particularly that of the Mishe Mokwa, Cordillera, and western Texoli buttes (Fig. 1), display a wealth of multi-scale sedimentary structures. Some of them indicate that complex wet-aeolian alternations occurred at the time of the deposition [3] as a continuation of the previously studied Mirador fm. (e.g., [4-5]). Yet, these outcrops have also revealed unprecedented clinoform geometries.Using image data acquired with ChemCam’s RMI, we detail three types of clinoform strata within the buttes surrounding this area (Fig. 1). These clinoforms differ in size and process from those recognized earlier in the mission at e.g., Kimberley [6]. Among them, we notably propose the first in-situ observation of deltaic geometries by Curiosity

    Perspectives du point de vue de l’analyse de l’activité des enseignants du premier degré dans le cadre du dispositif ALLIANCE

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    International audienceCadre théorique : Les enseignants du primaire jouent un rôle central dans la mise en œuvre des écoles promotrices de santé (Bowyer et al., 2023, Jourdan et al., 2016). Cependant, beaucoup manquent de confiance pour assurer l’éducation à la santé (ES), bien que cela fasse partie de leurs missions pédagogiques (Otten et al., 2024). Le dispositif ALLIANCE vise à renforcer l’autonomie et l’empowerment des enseignants en ES via la formation, l’accompagnement et la mise à disposition de ressources. La littérature scientifique montre que les pratiques pédagogiques en ES sont hétérogènes et n’ont pas toutes le même impact sur la littératie en santé des élèves (Lynagh et al., 2010 ; Petrie et al., 2014). ALLIANCE offre un cadre privilégié pour étudier comment les enseignants du primaire déclinent la promotion de la santé dans leurs pratiques pédagogiques et quels en sont les déterminants.Problématique : La communication se centre ici sur deux objectifs :1-Identifier les facteurs influençant l’engagement des enseignants en ES ;2-Analyser l’évolution de leurs pratiques en ES avant et après formation.Méthode : Les enseignants participant au dispositif ALLIANCE ont répondu chaque année à un questionnaire auto-administré validé portant sur leurs perceptions et pratiques en ES. L’objectif 1 a été traité à partir de données quantitatives recueillies avant formation (2019, n=243), via des régressions logistiques pour identifier les facteurs prédictifs de l’engagement en ES. L’objectif 2 a été traité à partir de réponses ouvertes collectées lors de suivis (2021, n = 75 ; 2022, n = 76). Les données ont été analysées lexicalement (analyse de fréquence et classification selon la méthode de Reinert) avec IRAMUTEQ.Résultats : L’engagement en ES était associé à des facteurs individuels (pertinence perçue de l’ES, intérêt, auto-efficacité), mais surtout collectifs et institutionnels (16 fois plus probable si l’enseignant a connaissance des pratiques des pairs, 11 fois plus s’il y a des initiatives à l’échelle de l’école). A l’inverse, travailler seul ou percevoir un décalage ressources/rôle freinait l’engagement. Les enseignants motivés uniquement par l’inclusion de l’ES dans le socle commun présentaient une intégration plus faible de l’ES dans leur pratique. Des analyses complémentaires évalueront si ces déterminants évoluent dans le temps grâce au dispositif.Les enseignants non formés adoptaient des pratiques plus thématiques (ex : nutrition, hygiène), tandis que ceux formés intégraient davantage les facteurs de protection tels que la littératie en santé et les compétences psychosociales. Ces résultats illustrent la capacité d’initiatives comme ALLIANCE à structurer les pratiques et renforcer l’empowerment des enseignants en ES. Ils mettent en évidence des parcours différenciés d’engagement et soulignent l’importance de développer des approches globales à l’échelle de l’école, pour favoriser une promotion durable de la santé en milieu scolaire

    Electroporation of spheroids using an electric field gradient: a tool to study intensity-dependent permeabilization

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    International audienceElectroporation (EPN) is the process by which cell membranes become transiently or permanently permeable upon exposure to pulsed electric fields of suitable intensity and duration. Depending on the pulse parameters, permeabilization can be reversible or irreversible, enabling a wide range of biomedical applications. To improve our understanding of EPN effects on tissues and select efficient treatments and parameters, relevant in vitro tumour models are required. Three-dimensional (3D) cell spheroids have emerged as valuable systems, as they more accurately replicate tumour microenvironment and cell-to-cell interactions than conventional 2D cultures. In this work, we present a new microdevice designed for the culture and gradual electroporation of a population of several hundred uniformly sized spheroids, allowing the systematic study of electroporation over a wide range of electric field intensities within a single experiment. Gradual permeabilization of HT-29 colorectal cancer cell spheroids was performed using a standard electrochemotherapy protocol, and electroporation efficiency was assessed by analysing propidium iodide (PI) uptake. Spheroids were treated with electric fields ranging from 800 V cm−1 to 3400 V cm−1. In toto analysis of PI distribution within spheroids by confocal microscopy revealed highly heterogeneous permeabilization patterns throughout the spheroid volume, for all intensities investigated, even at the highest one of 3400 V cm−1. This study introduces a robust 3D in vitro assay for the systematic evaluation of electroporation-based treatments, providing new insights into the influence of electric field heterogeneity, electrical protocol, and estimation of molecular uptake in the spheroid volume

    Measurement of the Zγγ production cross section and search for anomalous neutral triple gauge couplings in pp collisions at s\sqrt{s} = 13 TeV

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    International audienceA measurement of the fiducial cross section of the associated production of a Z boson and a high-pTp_\mathrm{T} photon, where the Z decays to two neutrinos, and a search for anomalous triple gauge couplings are reported. The results are based on data collected by the CMS experiment at the LHC in proton-proton collisions at s\sqrt{s} = 13 TeV during 2016-2018, corresponding to an integrated luminosity of 138 fb1^{-1}. The fiducial Zγγ cross section, where a photon with a pTp_\mathrm{T} greater than 225 GeV is produced in association with a Z, and the Z decays to a ννˉν\barν pair (Z(ννˉν\barν)γγ), is measured to be 23.31.3+1.4^{+1.4}_{-1.3} fb, in agreement, within uncertainties, with the standard model prediction. The differential cross section as a function of the photon pTp_\mathrm{T} has been measured and compared with standard model predictions computed at next-to-leading and at next-to-next-to-leading order in perturbative quantum chromodynamics. Constraints have been placed on the presence of anomalous couplings that affect the ZZγγ and Zγγγγ vertex using the pTp_\mathrm{T} spectrum of the photons. The observed 95% confidence level intervals for CPCP-conserving h3γh_3^γ and h4γh_4^γ are determined to be (-3.4, 3.5) ×\times 104^{-4} and (-6.8, 6.8) ×\times 107^{-7}, and for h3Zh_3^\mathrm{Z} and h4Zh_4^\mathrm{Z} they are (-2.2, 2.2) ×\times 104^{-4} and (-4.1, 4.2) ×\times 107^{-7}, respectively. These are the strictest limits to date on h3γh_3^γ, h3Zh_3^\mathrm{Z} and h4Zh_4^\mathrm{Z}

    Photochemical reactivity and fate of the toxic transformation product of naproxen in water

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    Dynamical System Modeling in Schizophrenia: A Narrative Review of Computational Psychiatry Frameworks

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    This is a preprint of the article submitted to "Dialogues in clinical neuroscience". The published version may differ, from the final version (accepted).The symptom dynamics in schizophrenia often exhibit complex, non-linear temporal patterns, alternating between relatively predictable and disorganized states. Conventional diagnostic frameworks often struggle to capture these evolving dynamics, prompting the development of diverse modeling approaches aimed at describing symptom trajectories more faithfully. Among these approaches, dynamical systems theory provides a particularly powerful framework for addressing temporal dependencies, non-linear interactions, and state-dependent transitions. Recent advances in longitudinal data collection and analysis, including improved temporal resolution and computational methods, now enable both the construction of interpretable models that distinguish distinct trajectories of symptom evolution and the extraction of informative dynamical features. This narrative review synthesizes the growing body of work applying dynamical systems theory to schizophrenia spectrum. It highlights convergent insights across studies while explicitly distinguishing between conceptually motivated models, emerging computational approaches, and empirically validated frameworks. This narrative review also addresses current limitations, including methodological constraints, issues of feasibility, and the need for further longitudinal and clinical validation. The aim is to provide a coherent conceptual framework for understanding schizophrenia as a dynamic process, to promote cross-disciplinary dialogue, and to guide future research in translational computational psychiatry

    Construction automatique d'un graphe de connaissances géo-historiques à partir de textes encyclopédiques anciens

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    National audienceLes encyclopédies anciennes, comme celle de Diderot et d'Alembert (1751-1772), offrent une ressource précieuse pour étudier l'évolution des savoirs géographiques, mais leur ampleur complique toute analyse manuelle. Cet article présente une méthode automatique de construction d'un graphe de connaissances géo-historiques à partir de ces textes. Nous proposons des ontologies spatiale et de provenance adaptées au corpus et introduisons un gold standard de 2 750 articles géographiques. Le pipeline combine apprentissage supervisé et grands modèles de langage pour la classification d'articles, le typage d'entités et l'extraction de relations spatiales. Les performances atteignent F1 = 92% pour les relations et F1 > 97% pour la classification, aboutissant à un graphe RDF de 35 000 entités et 46 000 relations. Ce travail ouvre la voie à l'analyse computationnelle des savoirs géographiques anciens

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