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High-intensity acute hospital physiotherapy for patients with hip fracture may improve functional independence and can reduce hospital length of stay [synopsis]
Flame acceleration and deflagration-to-detonation transition in micro- and macro-channels: An integrated mechanistic study
AbstractThe integrated processes of flame acceleration, deflagration-to-detonation transition (DDT), and the resulting detonation propagation in micro- and macro-scale channels are simulated. It is found that the modes of flame acceleration and DDT in these two channels are different, being primarily controlled by viscosity and turbulent flame development, respectively. Furthermore, while boundary layer ignition is crucial for DDT in both channels, viscous wall friction is the key to self-sustained propagation in micro-channels, leading to momentum loss and consequently deficit of the detonation velocity. In macro-channels, the strong overdriven detonation decays and gradually evolves into the Chapman–Jouguet detonation
Trophic overlap between wolves and free-ranging wolf × dog hybrids in the Apennine Mountains, Italy
AbstractHybridization between wolves (Canis lupus) and domestic dogs (Canis familiaris) can represent a threat to wild populations via genetic introgression and ecological competition. Therefore understanding the ecological role of hybrids may be crucial for developing appropriate conservation strategies.The Italian wolf population has a peculiar genetic composition due to a long-lasting geographic isolation. Nowadays, however, its genetic integrity is threatened by the spread of canine genes as a result of the hybridization with stray dogs in the wild.The aim of the present study was to gain insights into the ecological role of free-ranging wolf–dog hybrids by investigating their winter food habits in comparison with wolves in a mountain area of Central Italy. Levels of genetic introgression from the dogs were assessed in two adjacent areas occupied by up to five different packs by analyzing non-invasive samples and carcasses collected therein with a set of uniparental and bi-parental molecular markers.The obtained results enabled us to classify the two areas as ‘hybrid’ and ‘wolf’ areas based on their level of genetic introgression.Trophic niche and similarity/dissimilarity analyses did not detect significant difference in the diet between the two areas: in both of them, wild boar was the main prey, followed by roe deer. Furthermore, the same age/body mass classes of the two ungulates were selected by wolves and hybrids. Our findings confirmed wolf–dog hybrids as potential competitors for wolves. Further studies on other aspects of their biology and ecology are recommended in order to better estimate the impact of hybridization on natural wolf populations
Learning scale-variant and scale-invariant features for deep image classification
AbstractConvolutional Neural Networks (CNNs) require large image corpora to be trained on classification tasks. The variation in image resolutions, sizes of objects and patterns depicted, and image scales, hampers CNN training and performance, because the task-relevant information varies over spatial scales. Previous work attempting to deal with such scale variations focused on encouraging scale-invariant CNN representations. However, scale-invariant representations are incomplete representations of images, because images contain scale-variant information as well. This paper addresses the combined development of scale-invariant and scale-variant representations. We propose a multi-scale CNN method to encourage the recognition of both types of features and evaluate it on a challenging image classification task involving task-relevant characteristics at multiple scales. The results show that our multi-scale CNN outperforms single-scale CNN. This leads to the conclusion that encouraging the combined development of a scale-invariant and scale-variant representation in CNNs is beneficial to image recognition performance
Genome sequence of Bradyrhizobium embrapense strain CNPSo 2833T, isolated from a root nodule of Desmodium heterocarpon
AbstractBradyrhizobium embrapense CNPSo 2833T is a nitrogen-fixing symbiont of the legume pasture Desmodium. Its draft genome contains 8,267,832bp and 7876 CDSs. The symbiotic island includes nodulation and nitrogen fixation genes resembling the operon organization of B. japonicum. Several CDSs related to secretion proteins and stress tolerance were also identified
A new ion selective electrode method for determination of oseltamivir phosphate (Tamiflu) and its pharmaceutical applications
AbstractOseltamivir phosphate (OP) is an antiviral drug that is used in the treatment and prophylaxis of both influenza A and influenza B. It is effective against all known influenza viruses that can infect humans, including pandemic influenza viruses and may be the most appropriate antiviral option against avian influenza caused by H5N1 virus. Tamiflu, the registered trademark used under exclusive license by Roche laboratories with OP as active pharmaceutical ingredient, is considered the best treatment for the bird flu disease.The construction and electrochemical response characteristics of poly vinyl chloride (PVC) membrane sensors for the determination of (OP) were described. The sensors are based on the use of the ion association complexes of (OP) cation with sodium tetraphenylborate–oseltamivir phosphate (NaTPB–OP), tungestosilisate–oseltamivir phosphate (TS–OP), phosphomolbdate–oseltamivir phosphate (PM–OP) and phosphotungestate–oseltamivir phosphate (PT–OP) as ion exchange sites in the PVC matrix. The performance characteristics of these sensors, which were evaluated according to IUPAC recommendations, reveal a fast, stable and linear response for (OP) over the concentration range from 10−5 to 10−2molL−1 with cationic slopes of 51.5±0.3, 50±0.5, 55±0.2 and 50±0.4mV per decade across an extended OP concentration range from 1.0×10−6 to 1.0×10−2molL−1 for NaTPB–OP, TS–OP, PM–OP and PT–OP, respectively. The direct potentiometric determination of (OP) using the proposed sensors gave average recoveries of 99.9, 99.8, 99.9 and 99.7 for NaTPB–OP, TS–OP, PM–OP and PT–OP, respectively. The sensors are used for determination of (OP) in tablets. The method was successfully applied to commercial pharmaceuticals, Tamiflu. Validation of the method shows suitability of the proposed sensors for use in the quality control assessment of (OP). The developed method was found to be simple, accurate and precise when compared with a reported HPLC method
Self-organization of nickel nanoparticles dispersed in acetone: From separate nanoparticles to three-dimensional superstructures
AbstractSonochemical synthesis of monodisperse nickel nanoparticles (Ni-NPs) by reduction of Ni acetylacetonate in the presence of polyvinylpyrrolidone stabilizer is reported. The Ni-NPs size is readily controlled to 5 nanometer diameter with a standard deviation of less than 5%. The as-prepared Ni-NPs sample was dispersed in acetone, for 4weeks. For structural analysis was not applied to a magnetic field or heat treatment as key methods to direct the assembly. The transition from separate Ni-NPs into self-organization of three dimensions (3D) superstructures was studied by electron microscopy. Experimental analysis suggests that the translation and rotation movement of the Ni-NPs are governed by magnetic frustration which promotes the formation of different geometric arrangements in two dimensions (2D). The formation of 3D superstructures is confirmed from scanning electron microscopy revealing a layered domain that consists of staking of several monolayers having multiple well-defined supercrystalline domains, enabling their use for optical, electronic and sensor applications
The predictive power of airborne gamma ray survey data on the locations of domestic radon hazards in Norway: A strong case for utilizing airborne data in large-scale radon potential mapping
AbstractIt is estimated that exposure to radon in Norwegian dwellings is responsible for as many as 300 deaths a year due to lung cancer. To address this, the authorities in Norway have developed a national action plan that has the aim of reducing exposure to radon in Norway (Norwegian Ministries, 2010). The plan includes further investigation of the relationship between radon hazard and geological conditions, and development of map-based tools for assessing the large spatial variation in radon hazard levels across Norway. The main focus of the present contribution is to describe how we generate map predictions of radon potential (RP), a measure of radon hazard, from available airborne gamma ray spectrometry (AGRS) surveys in Norway, and what impact these map predictions can be expected to have on radon protection work including land-use planning and targeted surveying.We have compiled 11 contiguous AGRS surveys centred on the most populated part of Norway around Oslo to produce an equivalent uranium map measuring 180 km × 102 km that represents the relative concentrations of radon in the near surface of the ground with a spatial resolution in the 100 s of metres. We find that this map of radon in the ground offers a far more detailed and reliable picture of the distribution of radon in the sub-surface than can be deduced from the available digital geology maps.We tested the performances of digital geology and AGRS data as predictors of RP. We find that digital geology explains approximately 40% of the observed variance in ln RP nationally, while the AGRS data in the Oslo area split into 14 bands explains approximately 70% of the variance in the same parameter. We also notice that there are too few indoor data to characterise all geological settings in Norway which leaves areas in the geology-based RP map in the Oslo area, and elsewhere, unclassified. The AGRS RP map is derived from fewer classes, all characterised by more than 30 indoor measurements, and the corresponding RP map of the Oslo area has no unclassified parts. We used statistics of proportions to add 95% confidence limits to estimates of RP on our predictive maps, offering public health strategists an objective measure of uncertainty in the model. The geological and AGRS RP maps were further compared in terms of their performances in correctly classifying local areas known to be radon affected and less affected. Both maps were accurate in their predictions; however the AGRS map out-performed the geology map in its ability to offer confident predictions of RP for all of the local areas tested.We compared the AGRS RP map with the 2015 distribution of population in the Oslo area to determine the likely impact of radon contamination on the population. 11.4% of the population currently reside in the area classified as radon affected. 34% of ground floor living spaces in this affected area are expected to exceed the maximum limit of 200 Bq/m3, while 8.4% of similar spaces outside the affected area exceed this same limit, indicating that the map is very efficient at separating areas with quite different radon contamination profiles.The usefulness of the AGRS RP map in guiding new indoor radon surveys in the Oslo area was also examined. It is shown that indoor measuring programmes targeted on elevated RP areas could be as much as 6 times more efficient at identifying ground floor living spaces above the radon action level compared with surveys based on a random sampling strategy. Also, targeted measuring using the AGRS RP map as a guide makes it practical to search for the worst affected homes in the Oslo area: 10% of the incidences of very high radon contamination in ground floor living spaces (≥800 Bq/m3) are concentrated in just 1.2% of the populated part of the area
Mapping uranium concentration in soil: Belgian experience towards a European map
AbstractA map of uranium concentration in soil has been planned for the European Atlas of Natural Radiation. This Atlas is being developed by the Radioactivity Environmental Monitoring (REM) group of the Joint Research Centre (JRC) of the European Commission. The great interest in uranium compared to other terrestrial radionuclides stems from the fact that radon (222Rn) is in the decay chain of uranium (238U) and that public exposure to natural ionizing radiation is largely due to indoor radon.With several different databases available, including data (albeit not calibrated) from an airborne survey, Belgium is a favourable case for exploring the methodology of uranium mapping. A harmonized database of uranium in soil was built by merging radiological (not airborne) and geochemical data. Using this harmonized database it was possible to calibrate the data from the airborne survey.Several methods were used to perform spatial interpolation and to smooth the data: moving average without constraint, by soil class and by geological unit. When using the harmonized database, it is first necessary to evaluate the uranium concentration in areas without data or with an insufficient number of data points.Overall, there is a reasonable agreement between the maps on a 1 km × 1 km grid obtained with the two datasets (airborne U and harmonized soil U) with all the methods. The agreement is better when the maps are reduced to a 10 km × 10 km grid; the latter could be used for the European map of uranium concentration in soil
Lovelock gravities from Born–Infeld gravity theory
AbstractWe present a Born–Infeld gravity theory based on generalizations of Maxwell symmetries denoted as Cm. We analyze different configuration limits allowing to recover diverse Lovelock gravity actions in six dimensions. Further, the generalization to higher even dimensions is also considered