Naresuan University Journal
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International Federation for Public History Plenary Address: On Genealogy
No full textThis article argues for the importance of genealogy and family history to contemporary understanding and experience of the past. Through looking at various ways that genealogy might be undertaken and imagined, the article argues that this important area needs to be further conceptualized and studied by public historians. The article looks at the implications inherent in the broad shift to global online genealogy and family history. The argument is interrogative and assertive in order to provoke debate amongst public historians about how we might investigate, theorize, and interrogate genealogy and family history further in the future
Cloud computing: A Unique Business Model
No full textCloud Computing has developed into a catchphrase in industry today. It has become ever-present in the digital era as a result of the propagation of the Internet. It is one of the hottest topics in IT/IS and has become of significant interest to practitioners and academics due to its economic value. However, the benefits of cloud computing will not be fully achieved just on the basis of its economic value. This paper argues that cloud computing should be commercialized through an understanding of business models for any economic value to be achieved. This paper draws on the business model concept to illustrate how cloud can enhance unique opportunities for businesses seeking competitive advantage and why the business model concept should be the unique selling point for prospective adopters
Small fiber neuropathy in Parkinson's disease:A clinical, pathological and corneal confocal microscopy study
No full textUNLABELLED: Autonomic and somatic denervation is well established in Parkinson's disease (PD).OBJECTIVES: (1) To determine whether corneal confocal microscopy (CCM) can non-invasively demonstrate small nerve fiber damage in PD. (2) To identify relationships between corneal nerve parameters, intraepidermal nerve fiber density (IENFD) and clinical features of PD.METHODS: Twenty-six PD patients and 26 controls underwent CCM of both eyes. 24/26 PD patients and 10/26 controls underwent skin biopsies from the dorsa of both feet. PD patients underwent assessment of parasympathetic function [deep breathing heart rate variability (DB-HRV)], autonomic symptoms [scale for outcomes in Parkinson's disease - autonomic symptoms (SCOPA-AUT)], motor symptoms [UPDRS-III "ON"] and cumulative Levodopa dose.RESULTS: PD patients had significantly reduced corneal nerve fiber density (CNFD) with increased corneal nerve branch density (CNBD) and corneal nerve fiber length (CNFL) compared to controls. CNBD and CNFL but not CNFD correlated inversely with UPDRS-III and SCOPA-AUT. All CCM parameters correlated strongly with DB-HRV. There was no correlation between CCM parameters and disease duration, cumulative Levodopa dose or pain. IENFD was significantly reduced in PD compared to controls and correlated with CNFD and UPDRS-III. However, unlike CCM measures, IENFD correlated with disease duration and cumulative Levodopa dose but not with autonomic dysfunction.CONCLUSION: CCM identifies corneal nerve fiber pathology, which correlates with autonomic symptoms, parasympathetic deficits and motor scores in patients with PD. IENFD is also reduced and correlates with CNFD and motor symptoms but not parasympathetic deficits, indicating it detects different aspects of peripheral nerve pathology in PD.</p
Patient-reported outcome measures in psoriasis: the good, the bad and the missing!
No full textAs a long-term condition, psoriasis demands significant personal and professional input for optimal self-management. Low levels of well-being and high levels of psychological distress in patients with psoriasis are associated with reduced resources for self-care. Patient-reported outcome (PRO) measures can be used to assess physical, social and psychological functioning in order to guide treatment. In this article, we systematically reviewed the development and validation of existing PRO measures. PubMed (Medline), PsycINFO and CINAHL were searched systematically using predefined search terms. The search was limited to articles in the English language relating to human subjects. Articles were selected for full review through explicit inclusion/exclusion criteria. PRO measures were critically reviewed in accordance with the published guidelines and theory on the development and validation of PROs. The search identified 967 abstracts; 71 of these articles met the criteria for full review. In these 71 articles, 45 PRO measures were found: 16 were specific to psoriasis, 21 assessed other dermatological conditions and eight were developed for generic nondermatological health conditions. The review revealed several limitations of the existing measures, including: (i) a composite structure assessing multiple, poorly-defined concepts; (ii) a lack of evidence for face and content validity; (iii) a failure to include both patient and clinician perspectives and requirements and (iv) a lack of evidence regarding the feasibility and acceptability for patients and physicians. No single PRO measure with adequate evidence of validity, reliability and sensitivity to change captures patient well-being in psoriasis. A valid, sensitive, specific and acceptable PRO that assesses the full impact of psoriasis on well-being is needed for the comprehensive clinical management of psoriasis
Measurement of charged-particle spectra in Pb+Pb collisions at TeV with the ATLAS detector at the LHC
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Supporting End-User Service Composition: A Systematic Review of Current Activities and Tools
No full textThis paper presents a systematic literature review of end-user service composition. It reviews current activities performed by end users, and tools and approaches that enable them to compose and develop service systems from Web Services. The paper also highlights some key open research issues for the future
Measurement of the differential cross-section of highly boosted top quarks as a function of their transverse momentum in = 8 TeV proton-proton collisions using the ATLAS detector
No full textContribution of individual judgments toward inconsistency in pairwise comparisons
No full textPairwise comparison (PC) is a well-established method to assist decision makers in estimating their preferences. In PCs, the acquired judgments are used to construct a PC matrix (PCM) that is used to check whether the inconsistency in judgments is acceptable or requires revision. The use of Consistency Ratio (CR)—a widely used measure for inconsistency—has been widely debated and the literature survey has identified a need for a more appropriate measure. Considering this need, a new measure, termed congruence, is proposed in this paper. The measure is shown to be useful in finding the contribution of individual judgments toward overall inconsistency of a PCM and, therefore, can be used to detect and correct cardinally inconsistent judgments. The proposed measure is applicable to incomplete sets of PC judgments without modification, unlike CR which requires a complete set of PC judgments. To address ordinal inconsistency, another measure termed dissonance, is proposed as a supplement to the congruence measure. The two measures appear useful in detecting both outliers and the phenomenon of consistency deadlock where all judgments equally contribute toward the overall inconsistency
Aerosol chemistry above an extended archipelago of the eastern Mediterranean basin during strong northern winds
No full textDetailed aerosol chemical predictions by a comprehensive model system (i.e. PMCAMx, WRF, GEOS-CHEM), along with airborne and ground-based observations, are presented and analysed over a wide domain covering the Aegean Archipelago. The studied period is 10 successive days in 2011, characterized by strong northern winds, which is the most frequently prevailing synoptic pattern during summer. The submicron aerosol load in the lower troposphere above the archipelago is homogenously enriched in sulfate (average modelled and measured submicron sulfate of 5.5 and 5.8 mu g m(-3), respectively), followed by organics (2.3 and 4.4 mu g m(-3)) and ammonium (1.5 and 1.7 mu g m(-3)). Aerosol concentrations smoothly decline aloft, reaching lower values (<1 mu g m(-3)) above 4.2 km altitude. The evaluation criteria rate the model results for sulfate, ammonium, chloride, elemental carbon, organic carbon and total PM10 mass concentrations as "good", indicating a satisfactory representation of the aerosol chemistry and precursors. Higher model discrepancies are confined to the highest (e.g. peak sulfate values) and lowest ends (e.g. nitrate) of the airborne aerosol mass size distribution, as well as in airborne organic aerosol concentrations (model underestimation ca. 50 %). The latter is most likely related to the in-tense fire activity at the eastern Balkan area and the Black Sea coastline, which is not represented in the current model application. The investigation of the effect of local variables on model performance revealed that the best agreement between predictions and observations occurs during high winds from the northeast, as well as for the area confined above the archipelago and up to 2.2 km altitude. The atmospheric ageing of biogenic particles is suggested to be activated in the aerosol chemistry module, when treating organics in a sufficient nitrogen and sulfate-rich environment, such as that over the Aegean basin. More than 70% of the predicted aerosol mass over the Aegean Archipelago during a representative Etesian episode is related to transport of aerosols and their precursors from outside the modelling domain