International Journal of Research Development and Technology
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Evaluation of Anti-Diabetic Potential Of Helianthus Annuus Seed & Syzygium Cumini In The Suitable Experimental Model
Get PDFDiabetes Mellitus is a rapidly growing global health concern with significant morbidity and mortality rates. With the limitations of current treatment modalities, research focus is shifting towards exploring potential medicinal properties of natural substances. This study aims to investigate the anti-diabetic properties of Helianthus annuus (sunflower) seeds and Syzygium cumini (Java plum) in a relevant experimental model. These plants have been traditionally used in folk medicine, and previous studies have suggested potential anti-diabetic activity. Our research will focus on assessing their influence on blood glucose levels, insulin resistance, lipid profiles, and oxidative stress markers. The findings of this study will provide valuable insights into the therapeutic potential of these plants in diabetes management, contributing to the ongoing search for effective, safe, and affordable plant-based therapies for diabetes. A comprehensive evaluation may pave the way for the development of novel, plant-derived anti-diabetic therapies
Pharmacological activities and phytochemistry of alstonia scholaris
No full textAlstonia scholaris is a widely used plant in traditional medicine for various diseases and ailments.it has pharmacological properties beneficial to human health, it extract showed anti-stress, anti-oxidant, nootropic, cytotoxic, anti-cancer and anti-malarial effect. It also has anti-anxiety, anti-diabetic, antibacterial, anti-asthmatic, hepatoprotective anti-inflammatory and wound healing properties. phytochemical investigation reveals presence of alkaloids, flavonoids, terpenoids, glycosides and phenolic acid. Methanol extract of Alstonia scholaris’ flowers shows powerful antioxidant activity than fruits. The leaves are used for diahhroea, dysentery, malaria and snake bites
A Comprehensive Review of Aloe Vera: Health Benefits, Mechanisms of Action and Future Perspectives
Get PDFAloe vera, a kind of succulent plant with a long history of medicinal usage, has attracted a lot of interest recently because of its many health advantages. With an emphasis on aloe vera\u27s possible health-promoting characteristics, underlying mechanisms of action, and future opportunities for research and application, this in-depth review attempts to give a full examination of the scientific knowledge now available about it. The review covers a broad range of subjects, such as phytochemical composition, antioxidant activity, anti-inflammatory effects, wound healing capabilities, gastrointestinal advantages, immune-modulating properties, and probable anticancer action
Comprehensive Review of the Neem Plant\u27s Attributes and Applications
Get PDFThe neem plant (Azadirachta indica) is an ancient and versatile botanical resource that has been revered for its numerous medicinal, agricultural, and industrial applications. This review article provides a comprehensive examination of the neem plant, covering its botanical description, traditional uses, chemical composition, and pharmacological properties. The introduction highlights the historical, cultural, and economic significance of the neem plant, emphasizing its widespread utilization in traditional medicine, agriculture, and various other domains. The botanical description and taxonomy section offer a detailed overview of the neem plant\u27s characteristics, including its scientific classification and morphological features. Exploring the traditional and historical uses of the neem plant, this article presents its diverse applications in different cultures and regions. It discusses its role in traditional medicine, agricultural practices, pest control, cosmetic preparations, and cultural rituals, showcasing the long-standing cultural importance of the neem plant. The chemical composition section delves into the bioactive compounds found in the neem plant, such as nimbin, azadirachtin, nimbolide, and limonoids. Extraction methods for these compounds are also discussed, shedding light on their potential applications. The pharmacological properties section examines the extensive research on the neem plant\u27s antimicrobial, antiviral, antifungal, antidiabetic, anti-inflammatory, and antioxidant activities. It explores the mechanisms of action and the therapeutic potential of neem-derived compounds, offering insights into their biomedical applications
Survey of Sisanie Grandiflora Nephropathy Diabetic Action
Get PDFThe Sesbania grandiflora is utilised in folk medicine for different ailments and infections as tuberculosis, anaemia, microbial infections, etc. Additionally, S.grandiflora is utilised as a strong As a traditional medicine, Sesbania gran many parts offer a wide range of pharmacological actions to treat conditions like diabetes, liver disorders, antioxidant properties, hypouricemia activity, and enzyme inhibitors. Sesbania has 60 global species that can be found. These species are typically found in Australia, Africa and Asia. All components of the plant have various therapeutic properties. Pharmacologists are seeking to produce innovative drugs from natural sources, notably Sesbania grandiflora. The therapeutic usefulness, pharmacological activity, and medicinal qualities of Sesbania grandiflora are the subjects of the current review
Formulation and Evaluation of Venlafaxine Sustained-Release Tablets for Improved Patient Compliance: A Comprehensive Review
Get PDFThe prevalence of major depressive disorder and anxiety disorders has highlighted the need for more effective and patient-friendly therapeutic approaches. Among these, Venlafaxine, a serotonin-nor epinephrine reuptake inhibitor (SNRI), is an often prescribed medication. However, its twice-daily dosage regimen can be inconvenient, leading to non-compliance. To address this issue, the development of sustained-release formulations of Venlafaxine is becoming increasingly relevant. This review paper comprehensively discusses the formulation and evaluation of Venlafaxine sustained-release tablets, with an emphasis on how this approach may enhance patient compliance
A Review of Recent Advancement of Transdermal Drug Delivery Systems
Get PDFIt works pretty simply; a medication is placed within patch, which is then worn on skin for an extended period of time. This results in a sustained medication concentration in blood for a considerable amount of time. A polymer matrix, a drug, & permeation enhancers are three main components of TDDS. Polymers can be either natural or manufactured & include Zein & Shellac as well as Poly-butadiene, Polysiloxane, Polyvinyl Chloride & Polyvinyl Alcohol. Reservoir & matrix systems, single layer drug in adhesive, multi layer drug in adhesive are some of several configurations of TDDS. More than 35 products are currently approved for sale in US, & roughly 16- active components are approved for use as TDDSs globally, indicating rapid expansion of the market for TDDS goods. Transdermal drug delivery is covert component of therapy employed in general population, despite fact that developing nations like INDIA have second biggest population & are also most expensive. TDDS is a relatively new technology that has potential to significantly decrease use for needles while dispensing a range of medications
Navigating the Complexities of Alopecia Areata: A Comprehensive Analysis
Get PDFOne prevalent type of body and head hair loss that doesn\u27t leave scars is called alopecia areata (AA). In this Review, we studied the Pathogenesis of Alopecia Areata, Epidemiology, Cells implicated in alopecia areata immune reactions, Immunology, Environmental Factors, Genetic Factors, Causes of alopecia areata, Traditional Treatments of alopecia areata. The peer-reviewed literature release from 2010 & 2022 was thoroughly searched using Medline, Embase, Amed, Co-chrane Central Register of Controlled Trials, Psych INFO & Lilacs. All randomized controlled studies (RCTs) thatassessed efficacy systemic therapies for people with alopecia areata, totalis & universalis were included
Photochemical Properties and Biological Activities of Bauhinia Varigata: A Comprehensive Review
Get PDFA little orchid tree is known as Bauhinia variegata linn. It also goes by the name "kachnar." It is a member of most archaic subfamily of the (Caesalpinoideae) and family “Leguminosae”. It is a medicinal plant & different parts of plant are used in hemio-pathy, unani & ayurveda in India to treat a variety of diseases. These parts of plant include leaves, flower buds & flowers, stem bark, root bark & stem seed. All crude evaluations of the arial portion of the bauhinia variegate linn for in (vitro and vivo) were made. The chemical components flavonoids, glycoside, steroids, tannins & reducing sugar that were so far identified from plants. The pharmacological properties of Bauhinia variegate Linn include anti-oxidant, antibacterial, anti-cancer, anti-diabetic, antiinflammetory, antiulcer, Nephroprotective action, immunomodulator effect & last wound healing activity. The current study is based on a review article that presented screening of B.V. linn in phyto-chemical activity and biological activity as well as future research on B.V. linn
Self Nanoemulsions for Oral Drug Delivery: A Comprehensive Review
Get PDFNanotechnology is firmly acknowledged as significant methodology in drug conveyance that could impact the remedial exhibition of hydrophobic medications. SNEDDS are one of demonstrated strategies that can expand solvency & bioavailability of ineffectively H2O solvent medications. SNEDDS are anhydrous homogenous fluid combinations comprising of oil, surface active agent, co-surfactant, & medications, which suddenly structure o/w Nano- emulsions when weakened with water under delicate fomentation. SNEDDS give a few likely impacts on oral medication conveyance. This article presents an outline of SNEDDS alongside their fundamentals, for example, piece, arrangement, portrayal, potential impacts related with oral conveyance, applications, monetarily accessible items, cutting edge innovation related with SNEDDS & moving