RepOD Repository for Open Data
Not a member yet
3261 research outputs found
Sort by
Impact of monodiets on the development of hypopharyngeal glands and modulation of enzymatic, non-enzymatic, and ionic biomarker activities in selected fat body segments and hemolymph of honey bee workers
No full textIn this study, we examined the effects of monofloral pollen diets based on wind-pollinated plants (Corylus sp., Pinus sp.) and insect-pollinated plants (Brassica napus L., Phacelia sp., Solidago sp., Fagopyrum sp.) on the development of hypopharyngeal glands (HPGs), activities of enzymatic (AST, ALT, ALP, GGTP) and non-enzymatic (urea, uric acid) biomarkers, as well as magnesium, calcium, and phosphorus concentrations in the hemolymph and fat body from different locations (tergite 3, 5 and sternite) of worker bees. </p
Procesy o czary na Pomorzu Zachodnim XVI-XVIII wiek
No full textAkrusz zawiera zestawienie podstawowych informacji o procesach o czary Na Pomorzu zachodnim od XVI do XVIII wieku. Podano rok procesu, miejsce, obecny Amt lub gminę, rodzaj sądu, imię i nazwisko osoby sądzonej, płeć, wyrok oraz odniesienia do źródeł informacji.</p
IsoFMiR: An unsupervised anomaly detection framework for biomarker discovery in rare cancers
No full text<Description of the project>Identifying microRNA (miRNA) biomarkers in rare cancers remains a major challenge due to limited patient cohorts and high tumor heterogeneity. To overcome these limitations, we developed IsoFMiR — an unsupervised anomaly detection framework designed to discover cancer-specific miRNA signatures without relying on large, labeled datasets. Built upon the Isolation Forest algorithm, IsoFMiR leverages the concept that samples from rare cancers such as sarcomas exhibit distinct molecular patterns when compared to more common malignancies. By training the model on miRNA expression profiles from abundant cancer datasets and subsequently applying it to sarcoma samples, IsoFMiR isolates anomalous expression signatures that may represent potential biomarkers.This approach addresses key limitations of conventional supervised learning methods, which often fail when applied to data-scarce conditions. Through this unsupervised design, IsoFMiR facilitates robust biomarker discovery, even in cases where annotated samples are minimal. The framework was implemented using Python 3.11.9 and R 4.4.2, with the Scikit-learn library employed for building the Isolation Forest model. Sequencing data were sourced from publicly available repositories such as The Cancer Genome Atlas (TCGA) and XenaBrowser, ensuring transparency and reproducibility.Overall, IsoFMiR represents a scalable and data-efficient framework that enables the identification of clinically relevant miRNA biomarkers in rare cancers. By combining unsupervised learning with accessible genomic resources, it paves the way for improved understanding of sarcoma biology and the development of novel diagnostic and prognostic strategies.<Data ACCESS INFORMATION>GDC TCGA: https://portal.gdc.cancer.gov/Xena Browser: https://xenabrowser.net/<Description of the code>This set of scripts allows for running the IsoFMir algorithm. Each script is described below and should be used in the exact sequencial order.Creating_Training_Data_Set → Reads multiple CSV files containing microRNA data, extracts patient information, and generates a training dataset with up to n patients.Patients_Not_Used_For_Training → Creates a dataset of patients excluded from training. Provide the paths to the training data and patient information files generated by the Creating_Training_Data_Set script.Training → Trains an Isolation Forest model using microRNA data from non-sarcoma cancer samples.Testing → Evaluates the model’s ability to distinguish sarcoma samples from other cancer types.Consensus_and_SHAP_Analysis → Performs consensus and SHAP analyses. The script randomly selects 50 test samples by default; this number can be adjusted as needed.Overall_Survival_Code → Calculates overall survival for the selected microRNAs in sarcoma patients.</p
Dane litologiczne wybranych profili otworów wiertniczych Górnośląskiego Zagłębia Węglowego na potrzeby modelowania cykliczności sedymentacji
No full textPlik excel zawiera informację o wydzieleniach litologicznych w poszczególnych interwałach głębokościowych wybranych profili otworów wiertniczych Górnośląskiego Zagłębia Węglowego. Dane te zostały skomponowane dla celu modelowania cykliczności sedymentacji Krakowskiej Serii Piaskowcowej i powiązania jej z czynnikami astronomicznymi.</p
Photochemical Functionalization of 4-Diazoisoquinoline-1,3(2H,4H)-diones and Their 1-Sulfoxide Analogues
No full textIsoquinoline-1,3(2H,4H)-diones have been the subject of numerous studies toward new pharmaceuticals, and therefore novel, mild functionalizations of this scaffold are highly desirable. As diazo compounds are versatile reagents in organic synthesis, 4-diazoisoquinoline-1,3(2H,4H)-diones should give access to a broad range of various derivatives. Indeed, they enable the introduction of fluorinated moieties via photochemical O–H insertion reactions in serviceable yields, typically in under 2 h. Exchanging the 1-carbonyl group with the sulfoxide moiety causes a hypsochromic shift in the absorption of the diazo compounds, and thus, violet light is required for effective O–H and S–H insertion reactions.</p
Role of Minor Phase Morphology on Mechanical and Shape-Memory Properties of Polylactide/Bio-Polyamide Nanocomposite
No full textThe deposited data contain results obtained from measurements: SEM, DSC, DMA, 2D-SAXS, and tensile tests.The attached data are provided in the form of text and Excel files as well as source files typical for the respective software used.The attached data were obtained using the following instruments: Instron-5582 (Universal Testing Machine, HighWycombe, UK) at a strain rate of 5%/min according to ISO 527-2; Q800 DMA (TA Instruments, New Castle, DE, USA) to measure the thermomechanical characteristics of rectangular samples (24 × 10 × 0.75 mm³) at a heating rate of 2°C/min; The melting and non-isothermal crystallization of samples were examined by employing an indium-calibrated differential scanning calorimeter DSC Q20 (TA Instruments, New Castle, DE, USA); The morphology of cryogenic fractures recorded with JEOL JSM-5500 LV (Scanning Electron Microscope, Tokyo, Japan), In Situ 2D Small-Angle X-ray Scattering (SAXS), was facilitated by employing a home-assembled in situ SAXS apparatus, where a Linkam MicroTester, TST350 (Tadwarth, UK), was connected to a GeniX Cu-LD (Xenocs SAXS Instrument, Sassenage, France). </p
Multi-state emission of TICT luminophores
No full textIn this work, we address the challenge of designing versatile luminophores that maintain their emissive properties across various phases, including solutions and solid states (dual-state emission, DSE). We report the synthesis and detailed characterization of a series of Twisted Intramolecular Charge Transfer (TICT)-type luminophores with D-A-D molecular geometries composed of triphenylamine (TPA) or dimethylphenylamine fragments as donors (D) and aromatic ortho-substituted aldehydes as acceptors. In solutions, they show polarity-dependent solvatochromism, with emissions ranging from 500 to 600 nm. Importantly, their luminescence persists even in restrictive environments, such as crystalline, aggregated states, mechanically treated solids, and solid polymer matrices (PMMA). This durable condensed-phase luminescence results from their non-planar structure, particularly the ortho-substituted acceptor and propeller-shaped donor components, which effectively hinder harmful H-type stacking interactions linked to aggregation-induced quenching (AIQ), leaning more toward characteristics similar to aggregation-induced emission (AIE). Crystallographic data and theoretical calculations confirm the presence of twisted biaryl D-A fragments with D-A angles of 41-45°, a structural feature vital for preventing efficient solid-state stacking. Additionally, we find that these luminophores can undergo further twisting, showing a mechanochemically induced batochromic shift in luminescence (mechanochromism). The most sterically hindered compound consistently exhibits higher photoluminescent quantum yields under various conditions. Our results, supported by structural analysis, suggest that multi-state luminescence is a common trait among D-A-D-type twisted molecules, with significant potential for future development.</p
Evaluation of the effect of dietary fat derived from Hermetia illucens larvae added in broiler chicken diets on cecal microbiome compared to commonly used dietary fats in poultry nutrition
No full textThe dataset includes results from an in vivo experiment conducted on broiler chickens, randomly assigned to 8 experimental groups. The birds were fed diets containing fat from Hermetia illucens larvae, soybean oil, rapeseed oil, palm oil, palm fatty acid distillate, poultry fat, pig lard, and beef tallow. On the last day of the experiment (35d), biological material, i.e., cecal content was collected for next generation sequencing (NGS).Data contains a ReadMe.txt file.</p
Investigation of gasochromic properties in tungsten oxide thin films prepared by glancing angle deposition using electron beam evaporation
No full textFiles include the data presented in the manuscript entitled: "Investigation of gasochromic properties in tungsten oxide thin films prepared by glancing angle deposition using electron beam evaporation" by Weichbrodt et al. (https://doi.org/10.1364/AO.574156).Fig. 2a presents X-ray diffraction results of as-deposited WO3 thin films deposited with the use of GLAD technique at various anglesFig. 2b presents X-ray diffraction results of WO3 thin films deposited with the use of GLAD technique at various angles and annealed at 400CFig. 2c presents Raman spectroscopy measurements results of as-deposited WO3 thin films deposited with the use of GLAD technique at various anglesFig. 2d presents Raman spectroscopy measurements results of WO3 thin films deposited with the use of GLAD technique at various angles and annealed at 400CFig. 6 presents normalized transmission change at 900 nm shown upon exposure to hydrogen at concentrations ranging from 50 to 1000 ppm for as-deposited and annealed WO3 thin films prepared using the GLAD technique at an angle of: (a) 0, (b) 60, (c) 70, (d) 80, (e) 85, and (f) 88 degrees. Measurements were done using experimental setup for gasochromic research, including Ocean Optics QE65000 spectrophotometer and DH-BAL 2000 light source. Fig. 7ab presents measurements results of WO3 thin films exposed to 1000 ppm of H2: (a) normalized transmission at 900 nm for nanocrystalline WO3 thin films deposited at various angles, and (b) comparison of stability tests for thin films deposited at an angle of 0 and 88 degrees. Measurements were done using experimental setup for gasochromic research, including Ocean Optics QE65000 spectrophotometer and DH-BAL 2000 light source.</p
Innowacyjne układy napędowe wózków inwalidzkich – projekt, prototyp, badania
No full text[PL:]Dane badawcze projektu: „Innowacyjne Układy Napędowe Wózków Inwalidzkich – Projekt, Prototyp, Badania”, numer: „Rzeczy są dla ludzi/0004/2020”, finansowanego przez Narodowe Centrum Badań i Rozwoju, https://www.gov.pl/web/ncbr.Zbiór danych obejmuje wyniki badań biomechaniki napędzania wózków inwalidzkich wyposażonych w układy napędowe, w których zastosowano przekładnie mechaniczne. Wykorzystywano trzy prototypowe rozwiązania dla trzech różnych przełożeń. Oznaczenia i opis poszczególnych wariantów eksperymentu można odnaleźć w pliku: „Read me”Badania miały na celu ocenę efektywności procesu napędzania dla różnych wartości przełożenia pomiędzy kołem a ciągami. W zależności od wariantu wykonywano: pomiary na hamowni do wózków inwalidzkich, przechwytywanie ruchu, pomiary elektromiografii powierzchniowej oraz pomiary parametrów metabolicznych.[ENG:]Research Data of the Project: “Innovative Drive Systems for Wheelchairs – Design, Prototype, Research”, Project No.: “Rzeczy są dla ludzi/0004/2020”, funded by the National Centre for Research and Development, https://www.gov.pl/web/ncbrThe dataset comprises the results of studies on the biomechanics of wheelchair propulsion using drive systems incorporating mechanical transmissions. Three prototype solutions were examined, each characterized by a distinct gear ratio. The designations and detailed descriptions of the experimental variants are provided in the accompanying file: “Read me”.The primary objective of the research was to assess the efficiency of the propulsion process under varying gear ratios between the wheel and the pushrims. Depending on the experimental variant, the following measurements were carried out: wheelchair dynamometer testing, motion capture, surface electromyography, and metabolic parameter assessment.</p
Data sources:
Access Repository Dashboard
Do you manage RepOD Repository for Open Data? Access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard!