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Data from mathematical model of hydrogen peroxide (H2O2) neutralization
No full textData collected from mathematical model of hydrogen peroxide (H2O2) neutralization in breast, lung and colorectal cancer cell lines. The results demonstrate the H2O2 levels after neutralization through different neutralization systems. The H2O2 neutralization pathways used in the model utilize the following enzymes: peroxiredoxin (PRDX) with thioredoxin (TXN), glutathione peroxidase (GPX) with glutathione (GSH), and catalase (CAT) or their combinations. Obtained data were used to assess the role of different enzymes in H2O2 neutralization and estimation of cellular radioresistance due to activation of specific neutralization pathway(s).</p
Induction of Infectious Pancreatic Necrosis (IPN) in brook trout (Salvelinus fontinalis) and rainbow brook trout (Salvelinus fontinalis x Oncorhynchus mykiss) using microinjection challenge with infectious pancreatic necrosis virus (IPNV)
No full textThe datasets are part of research aimed to compare the susceptibility to infection with Infectious Pancreatic Necrosis Virus (IPNV) of salmonids from the Salmoninae subfamily: brook trout Salvelinus fontinalis and its interspecific cross with rainbow trout, i.e., rainbow brook trout Salvelinus fontinalis x Oncorhynchus mykiss.</p
Experimental and numerical progress in the Ranque-Hilsch vortex tube investigation (CFD dataset)
No full textThis dataset contains numerical simulation results of airflow in a Ranque–Hilsch Vortex Tube (RHVT), obtained using ANSYS Fluent. The primary goal was to analyze the temperature separation phenomenon inside the vortex tube and validate the computational model against experimental data. The simulations were based on a turbulent flow model (k-ω SST) under specified inlet conditions. The dataset includes case and data files with full geometry, boundary conditions, solver setup, and computed flow fields (temperature, velocity, pressure). Results include temperature separation between hot and cold outlets and pressure distribution along the tube.Although the original simulation was performed in ANSYS Fluent (commercial software), the study can be reproduced using non-commercial open-source software, such as OpenFOAM, which supports k-ω SST turbulence modeling, compressible flow, and thermal analysis.</p
Anabaenopeptin-A, anabaenopeptin-B, aeruginosin-98B, their binary and ternary mixtures alter biochemical biomarkers, tyrosine phosphatase and HSP70 heat shock protein of Daphnia magna
No full textZbiór danych otwartych dotyczący projektu NCN pt. "Ocena oddziaływania in vivo oraz in vitro sinicowych oligopeptydów na organizmy wodne" nr 2019/35/B/NZ9/03249 dotyczący wpływu metabolitów sinicowych na organizmy wodne. Zbiór zawiera dane opublikowane w pracy pt. "Anabaenopeptin-A, anabaenopeptin-B, aeruginosin-98B, their binary and ternary mixtures alter biochemical biomarkers, tyrosine phosphatase and HSP70 heat shock protein of Daphnia magna" opublikowanej w czasopismie Toxicon. Zbiór zawiera 4 pliki zawierające dane odczytu z czytnika wielofunkcyjnego testów ELISA Synergy z zastosowaniem programu Gen5 3.11 w formacie .xlsx do odczytu w programie Excel. Pliki zawierają w tytule typ badanego parametru testowanego bezkręgowca i koncentracji metabolitów sinicowych. Rodzaj metabolitu wraz ze stężeniami jest ukazany pod poszczególnych wellsach u dłu formatu mikropłytki Zastosowane skróty: ANA-A –anabaenopeptin-A, ANA-B - anabaeopeptin-B AER-B-aeruginosin 98B, HSP70- hest shock protein 70 kDa, NO-nitric oxide</p
Factors of local food purchasing
No full textThe food market is very sensitive to any changes in the environment. It is one of the fastest growing markets, but also the most vulnerable to any changes related to, for example, restrictions, regulations and trends for specific products. The results obtained allowed us to identify products appreciated by respondents, such as eggs, dairy products and groats. Local alcoholic beverages in the ‘local wines’ and ‘craft beers’ categories were more appreciated by men. Locally produced oils were the least popular among respondents. Among the characteristics that consumers associate with local food are producer identification, freshness, good taste and affordability. Consumers take advantage of short supply chains, such as buying directly from the producer, or take the opportunity to buy during local events or themed trips, e.g. on a culinary trail. Consumers are willing to accept a price increase of 10-15%, but with larger increases they start looking for cheaper substitutes. The local product market is a source of support for the local economy, so it is the task of the authorities to create conditions for its development through appropriate measures to promote local products.</p
Wpływ wyciszenia AK4 na metabolizm i kinom komórek endotelium
No full textZbiór danych zawiera wyniki pojedynczego działania naukowego zrealizowanego w ramach konkursu MINIATURA finansowanego przez Narodowe Centrum Nauki. Celem przepowadzonych badań było wstępne poznanie efektów wyciszenia genu AK4 (kinazy adenylanowej 4) na metabolizm ludzkich pierwotnych komórek śródbłonka mikronaczyń płucnych (HPMEC) pozyskanych od trzech donorów, w warunkach normoksji i hipoksji (niedotlenienia). Wyciszanie genu AK4 przeprowadzono metodą bezwektorową z wykorzystaniem syntetycznych sekwencji siRNA. W badaniach zastosowaną niecelowaną analizę metabolomiczną z użyciem spektrometrii mas (QExactive Hybrid Quadrupole-Orbitrap), jak również technologię Seahorse w celu zbadania aktywności glikolitycznej w czasie rzeczywistym. Dodatkowo, dzięki współpracy z Uniwersytetem Justusa Liebiga w Giessen (Niemcy) zbadano efekt wyciszenia AK4 w komórkach HPMEC od trzech donorów na aktywność kinaz białkowych techniką mikromacierzy peptydowych (PamGene). Wyniki uzyskane w ramach zrealizowanego działania naukowego wskazują, że AK4 może regulować metabolizm podstawowy komórek HPMEC przez kontrolę szlaku glikolizy i cyklu TCA oraz szlaków transdukcji sygnałów zależnych od kinaz białkowych z rodziny Src i CDK. Należy podkreślić, że niecelowana analiza metabolomiczna oraz profilowanie kinomu to globalne analizy przesiewowe pozwalające wytypować możliwie najwiekszą liczbę metabolitów/sygnałów. Przed publikacją pełnego oryginalnego artykułu naukowego, zaplanowane jest potwierdzenie zidentyfikowanych różnic z wykorzystaniem analiz celowanych, np. z wykorzystaniem metabolomiki celowanej, testów biochemicznych i funkcjonalnych.</p
Data of analysis of the combined effect of diversified Zn(II) content in the diet and Cr(III) supplementation on the body composition in Wistar rats
No full textThe data concern the combined effect of diversified Zn(II) content in the diet and Cr(III) supplementation on the body composition (body weight, adipose tissue content, muscle tissue content, fluid content). The in vivo experiment was conducted on Wistar rats randomly assigned to 6 experimental groups with different dietary Zn levels (deficient D, recommended K, excess N) and at the same time supplemented with Cr(III) at doses of 1 and 50 mg/kg for 6 weeks (5-6 males and 6 females). The study adhered to strict ethical standards for animal research and was approved by the Local Ethical Committee in Poznań, Poland (No. 48/2018). Measurements were made using a MiniSpec IF90II laboratory animal body composition analyzer (Bruker LF, Germany).</p
Oddziaływanie niezależnych archiwów społecznych - Centrum Badań Mniejszości Niemieckiej
No full textZbiór zawiera dane badawcze wytworzone w toku drugiej fazy projektu pt. "Oddziaływanie niezależnych archiwów społecznych" (strona www projektu: https://impact.umk.pl/) realizowanego na Uniwersytecie Mikołaja Kopernika w Toruniu (2023-2026, kierownik: dr Magdalena Wiśniewska-Drewniak). Celem projektu jest zrozumienie społecznego i afektywnego oddziaływania niezależnych archiwów społecznych poprzez badania empiryczne oparte w szczególności na wywiadach jakościowych z osobami tworzącymi i związanymi z archiwami społecznymi.Druga faza projektu polega na terenowych badaniach w trzech wybranych archiwach społecznych (trzech przypadkach). W jej trakcie wykonywane są wywiady z osobami tworzącymi archiwum oraz z nim związanymi, w tym z darczyńcami oraz użytkownikami i odbiorcami działań.Niniejszy zbiór danych zawiera dane badawcze (wywiady i fotografie) zgromadzone w trakcie badań w pierwszym odwiedzonym w ramach projektu IMPACT archiwum społecznym - Centrum Badań Mniejszości Niemieckiej w Opolu.Dane zostały zgromadzone w sierpniu 2024 r. przez Magdalenę Wiśniewską-Drewniak.The collection contains research data produced in the course of the first phase of the project titled “Impact of independent community archives” (project website: https://impact.umk.pl/) carried out at Nicolaus Copernicus University in Toruń (2023-2026, Primary Investigator: Dr. Magdalena Wiśniewska-Drewniak). The aim of the project is to understand the social and affective impact of independent community archives through empirical research based in particular on qualitative interviews with people who create and are associated with community archives.The second phase of the project consists of field studies in three selected community archives (three cases). In the course of it, interviews are conducted with people who create the archives and those associated with them, including donors/contributors, users and recipients of the archive's activities.This dataset contains research data (interviews and photographs) collected during the study at the first community archive visited as part of the IMPACT project - the German Minority Research Center in Opole. The data was collected in August 2024 by Magdalena Wiśniewska-Drewniak.</p
Sedimentary ancient DNA insights into foraminiferal diversity near the grounding line in the western Ross Sea, Antarctica
No full textForaminifera are important marine environmental indicators widely used in paleoceanography and paleoclimate studies. They are a dominant component of meiobenthic communities around the Antarctic continental shelf, including rarely studied locations below the ice shelves, close to the grounding line. In this study, we use high-throughput sequencing of sedimentary ancient DNA (sedaDNA) targeting foraminifera with two molecular markers, including the ultra-short one newly designed for this study, in five cores from the western Ross Sea, containing sediments up to thirty thousand years old. No foraminiferal DNA is detected in the tills, suggesting a lack of preservation of sedaDNA during glacially induced sediment reworking and transport. We reconstruct diverse foraminiferal communities in the open marine settings and significantly less diverse communities in sediments from the slopes of the grounding zone wedges, deposited proximal to the grounding line. Both assemblages are rich in soft-walled monothalamids not preserved in the fossil record and complement the results of earlier micropaleontological studies, allowing a more complete reconstruction of past biodiversity. The newly designed mini-barcode provides higher foraminiferal diversity in surface and subsurface samples than the standard barcode and allows better differentiation between foraminiferal communities in different sediment types. It appears to have great potential for future paleoenvironmental studies, although its taxonomic resolution needs to be evaluated.</p
Hydrogel Microarray for Bioanalytical Applications: Preliminary Study on Material Properties
No full textThe aim of this study was to develop and characterize UV-crosslinked hydrogel matrices based on polyethylene glycol diacrylate (PEGDA), gum arabic, betaine, and sodium alginate for potential bioanalytical applications. Various physicochemical analyses were performed, including prepolymerization emulsion stability (Multiscan), FT-IR spectroscopy, swelling behavior in physiological buffers, pH monitoring, contact angle measurements, and morphological assessment via SEM and optical microscopy. The results demonstrated that both alginate content and UV exposure time significantly influence the structural and functional properties of the hydrogels. The highest swelling ratio (2.32 g/g) was observed for the formulation containing 5% sodium alginate polymerized for 5 min (5SA_5), though this sample showed mechanical fragmentation during incubation. In contrast, the most balanced performance was achieved for the 10SA_15 formulation, which maintained structural integrity and exhibited a swelling ratio of 1.92 g/g after 9 days. The contact angle analysis revealed a surface hydrophilicity range from 50◦ to 100◦, with the lowest angle (50◦) recorded for 10SA_5, indicating high surface wettability. These findings confirm the suitability of such hydrogels for biomedical applications, particularly as absorbent, stable platforms for drug delivery or wound healing.</p
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