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HORIZON EUROPE RIA PROJECT - CULTURATI_Deliverable D6.4 National Events Report 2
No full text<p>National Events Report 2 is the second deliverable documenting the national events organized as part of the project. This report presents an overview of the two national events successfully held as planned: the first in April 2024 at the Istanbul Rahmi M. Koç Museum in Türkiye and the second in October 2024 in Ascoli Satriano, Italy. It outlines the key discussions, participant engagement, and outcomes of these events, highlighting their contributions to the project's objectives.</p>
Fabrication of Gold Thin Films on Cooled Glass Substrates
No full text<p>In this article, gold (Au) thin films were fabricated on glass substrates under vacuum conditions (4.5 x 10(-6) Torr) within a temperature range of 100-300 K, incrementing in steps of 50 K. Analyses through Field Emission Scanning Electron Microscopy (FESEM) revealed that at a substrate temperature of 230 K, the films featured spherical clusters of uniform size, e.g., 11-12 nm, suggesting that the soliton growth mechanism predominates at this temperature. Atomic Force Microscopy (AFM) further demonstrated that the average surface roughness (Ra) of the Au films varied with the substrate temperature, ranging from 1.2 to 4.7 nm, with the smoothest film observed at 230 K. X-ray diffraction (XRD) analysis confirmed that all films exhibited a cubic crystal structure oriented in the (111) plane. Optical analyses indicated that the films produced across the entire substrate temperature spectrum showed surface plasmon excitation within the 520-600 nm wavelength range. To excite surface plasmons at longer wavelengths, the Au film fabricated at 230 K was annealed at 773 K under vacuum conditions for an hour, enlarging the grain size to similar to 15 nm. Post-annealing, optical measurements revealed a 70-nm shift in the peak position of the plasmonic resonance to a longer wavelength of 650 nm, showcasing the tunable nature of the plasmonic effects through thermal processing.</p>
Destructive impact of successive high magnitude earthquakes occurred in Türkiye's Kahramanmaraş on February 6, 2023
No full text<p>Two successive earthquakes with moment magnitudes of Mw = 7.7 (focal depth = 8.6 km) and Mw = 7.6 (focal depth = 7 km) occurred approximately within 9 h on February 6, 2023, in Turkiye, respectively. The epicenters were the Pazarcik and Elbistan districts of Kahramanmaras. Both earthquakes occurred in the East Anatolian Fault Zone, one of Turkiye's two major active fault systems. Between these two severe earthquakes, there was one more big aftershock with a moment magnitude of 6.6, the epicenter of which was in the Nurdagi District of Gaziantep. Then, on February 20, 2023, another aftershock earthquake with a magnitude of Mw = 6.4 occurred in Yayladagi district of Hatay. As a result of the earthquakes, severe damage occurred in several provinces and districts with a population of around 15 million, and more than 50,000 people have lost their lives. This study presents on-site geotechnical and structural investigations by a team of researchers after the Kahramanmaras earthquakes. It summarizes the performance of the building environments as a result of on-site assessments, taking into account observed structural damage, local site conditions, and strong ground motion data. The possible causes of the observed damage are addressed in detail. These earthquakes once again revealed the common deficiencies of existing reinforced concrete structures in Turkiye, such as poor material quality, poor workmanship, unsuitability of reinforcement detailing, and inadequate earthquake-resistant construction techniques. Precast concrete and masonry structures in the region were also severely damaged during the earthquakes due to insufficient engineering service, poor materials, deficiencies during construction, etc.</p>
Exploring Regulatory Roles of Transposable Elements in EMT and MET through Data-Driven Analysis: Insights from regulaTER
No full text<p>Gene expression is regulated at the transcriptional and translational levels and a plethora of epigenetic mechanisms. Regulation of gene expression by transposable elements is well documented. However, a comprehensive analysis of their regulatory roles is challenging due to the lack of dedicated approaches to define their contribution. Here, we present regulaTER, a new R library dedicated to deciphering the regulatory potential of transposable elements in a given phenotype. regulaTER utilizes a variety of genomics data of any origin and combines gene expression level information to predict the regulatory roles of transposable elements. We further validated its capabilities using data generated from an epithelialmesenchymal and mesenchymal-epithelial transition cellular model. regulaTER stands out as an essential asset for uncovering the impact of transposable elements on the regulation of gene expression, with high flexibility to perform a range of transposable element-focused analyses. Our results also provided insights on the contribution of the MIR and B element subfamilies in regulating EMT and MET through the FoxA transcription factor family. regulaTER is publicly available and can be downloaded from https://github. (c) 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.</p>
U-Pb Calcite Geochronology, EPR, Geochemistry, and C-O-Sr Isotopes of ancient marbles in the İznik Region (Bursa - Türkiye)
No full text<p>The İznik city (ancient Nicaea), located east of Lake İznik (known as "Bithynia" in ancient times), has been an important political and cultural centre of Asia Minor since the Hellenistic period. Marbles produced in the quarries in the vicinity (Ömerli and İnikli villages, Deliktaş - Sarıtaş hills) were used both in the construction of the walls and in many ancient works in the city. Approximately eighteen ancient marble quarries producing grey and white marbles were investigated in the region. Petrography, EPR, XRD, C-O-Sr isotope and whole rock geochemistry analyses were performed for characterization of the samples collected from the quarries for the provenance studies. According to the new geochemistry and C-O-Sr isotope data, the limestones forming the marbles were deposited in open sea - ocean environments. U-Pb calcite dating determined that the white marbles were 93.06 ± 8.55 Ma, while the grey marbles were 94.84 ± 1.41 Ma and 88.03 ± 2.13 Ma (Upper Cretaceous: Cenomanian-Coniacian). These ages probably correspond to the crystallization/metamorphism ages of the marbles. The new data set obtained with this study will contribute to the understanding of the geological evolution of the region, and will help researchers to better understand the source region of some white and grey marbles used in ancient buildings.</p>
Water Quality Assessment with Artificial Neural Network Models: Performance Comparison Between SMN, MLP and PS-ANN Methodologies
No full text<p>Identifying and measuring potential sources of pollution is essential for water management and pollution control. Using a range of artificial intelligence models to analyze water quality (WQ) is one of the most effective techniques for estimating water quality index (WQI). In this context, machine learning-based models are introduced to predict the WQ factors of Southeastern Black Sea Basin. The data comprising monthly samples of different WQ factors were collected for 12 months at eight locations of the T & uuml;rkiye region in Southeastern Black Sea. The traditional evaluation with WQI of surface water was calculated as average (i.e. good WQ). Single multiplicative neuron (SMN) model, multilayer perceptron (MLP) and pi-sigma artificial neural networks (PS-ANNs) were used to predict WQI, and the accuracy of the proposed algorithms were compared. SMN model and PS-ANNs were used for WQ prediction modeling for the first time in the literature. According to the results obtained from the proposed ANN models, it was found to provide a highly reliable modeling approach that allows capturing the nonlinear structure of complex time series and thus to generate more accurate predictions. The results of the analyses demonstrate the applicability of the proposed pi-sigma model instead of using other computational methods to predict WQ both in particular and other surface water resources in general.</p>
Supplementary_MetB16_TJB_Aperta
No full text<p>Dosya;<strong> </strong>Turkish Journal of Biology dergisinde yayınlanmak için kabul alan<strong> "Novel MRSA-targeting phage MetB16: Genomic features, structural insights, and therapeutic applications" </strong>isimli <strong>"TJBIO-2024-00442R1"</strong> kodlu yayınımızın Supplementary Material ekidir. </p>
The Effect of Immobilization Methods of P9-4 Antimicrobial Peptide Onto Gelatin Methacrylate on Multidrug-Resistant Bacteria: A Comparative Study
No full text<p>Wound dressings play a crucial role in wound management by providing a protective barrier and creating an optimal environment for healing. Photocrosslinkable hydrogels, such as gelatin methacrylate (GelMA), have gained attention for their unique properties but often lack antimicrobial activity. To enhance their effectiveness, researchers are exploring methods to incorporate antimicrobial agents into photocrosslinkable hydrogel dressings. Immobilization of antimicrobial peptides (AMPs) onto hydrogel matrices may be achieved through physical or chemical methods. Although, chemical immobilization, using techniques like EDC/NHS chemistry, has shown promise in enhancing antimicrobial properties of hydrogels, the capacity for immobilization may be limited by the structure of hydrogel. Physical methods, such as immersing, offer alternatives but may have different efficacy and biocompatibility. The study aims to chemically immobilize GelMA with P9-4 AMP by photoinduced conjugation and EDC/NHS chemistry and compare its antimicrobial efficacy with a physical immobilization method. Chemical immobilization by EDC/NHS chemistry significantly enhances the antimicrobial effect of GelMA hydrogels against multi-drug resistant Psuedomonas aeruginosa (MDR P. aeruginosa) and methicillin-resistant Staphylococcus aureus (MRSA) while maintaining favorable biocompatibility. Study highlights the potential of AMP-functionalized GelMA as advanced wound dressings for reducing infections caused by antibiotic-resistant bacteria and offers a promising approach for future research in wound management.</p>
<p>The study enhances GelMA hydrogels with AMPs using chemical and physical immobilization methods. Results show that EDC/NHS chemistry significantly improves GelMA's antimicrobial effects against MDR P. aeruginosa and MRSA while maintaining biocompatibility, presenting AMP-functionalized GelMA hydrogels as promising advanced wound dressings for combating antibiotic-resistant infections. image</p>
Design optimisation of a screw compressor with a focus on rotor depth: A computational fluid dynamics approach
No full text<p>The increasing demand for enhanced performance and reliability in twin-screw compressors necessitates the application of advanced optimisation tools to improve performance. This study employs response surface methodology (RSM) to optimise the profile parameters of a standard 5/6 compressor, specifically targeting reduction in specific power. Key factors such as axis distance between rotors and female rotor outer diameter, which define the rotor depth, were included in the present optimisation process. Following the optimisation of the rotor profile, port optimisation was also conducted using the same methodology. A multi-chamber thermodynamic analysis was performed with SCORGTM software, which allowed for the calculation of geometric values and thermodynamic quantities. The results of the rotor optimisation revealed notable improvements: a 4.30 % reduction in specific power, a 2.73 % increase in volumetric efficiency, a 3.93 % enhancement in adiabatic efficiency, and a 2.88 % rise in volumetric flow rate compared to the reference design. After port optimisation, both volumetric and adiabatic efficiencies of the optimised rotor profile remained comparable, while specific power was further reduced by 1.37 %. To validate the performance of the optimised compressor, computational fluid dynamics (CFD) analysis was conducted using a conformal mesh generated by SCORGTM and ANSYS CFX multiphase solver. The maximum deviation between the optimal results from SCORGTM and CFD was only 0.19 %, indicating strong agreement between the two methodologies. This study highlights the significant impact of optimisation techniques on the performance of twin-screw compressors.</p>
Comparative study of virgin and recycled polyethylene terephthalate and polypropylene intermingled thermoplastic composites
No full text<p>In this study, a comparative analysis of the use of recycled PET (R-PET) in synthetic and natural fiber blended composites was made. PET, R-PET, and PP yarns were folded with reinforcing fibers by commingling technique and then fabrics were prepared using weaving technology. Hot compression molding technology was used for composite fabrication. Tensile and impact characterization revealed the significant influence of reinforcing and TP fibers on mechanical properties. R-PET matrix glass fiber reinforced composites exhibited 41.77% higher tensile strength than virgin PET and 20.41% higher than PP. In terms of tensile strength for linen reinforced samples, R-PET shows an impressive 181% improvement over virgin PET and 154% over PP. According to the drop weight test results, glass fiber reinforced R-PET matrix sample exhibited a peak load value 53% higher than that of the virgin PET matrix, although it was 9.47% lower than the PP matrix. In linen fiber reinforced samples, R-PET demonstrated a 57.73% improvement over virgin PET but lower by 9.47% compared to the PP matrix. During this time, DSC, TGA, FTIR, and flammability tests were also performed on the composite samples. The results showed that R-PET has easy processability as a matrix material and provides better wetting of the reinforcing fibers. For this reason, it has been shown that R-PET matrix samples provide better mechanical properties than both PET and PP matrix samples. It has also been determined that R-PET is a more suitable matrix material compared with natural fiber reinforced composites.Highlights Commingled yarns were used for preparing composites. R-PET yarns were used as matrix in preparing glass and linen reinforced composites. R-PET was compared with virgin PET and PP yarns. R-PET showed great potential in easy preparation of TP composites. Composites made with R-PET showed improved thermal and mechanical properties.</p>