Dane Badawcze UW University of Warsaw
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pAcOrn–BISS/Al3+ hydrogels based on derivatives of natural amino acids for sensing activity
No full textThis dataset presents a series of multifunctional hydrogels developed using aluminum ion (Al3+) coordination chemistry to enhance self-healing, mechanical strength, and sensing performance. These hydrogels are built from poly(N-δ-acryloyl ornithine) (pAcOrn) monomers and crosslinked with N,N′-bisacryloylcystine (BISS), alongside varying concentrations of Al3+ ions. The aluminum ions interact dynamically with amino acid side chains, introducing reversible coordination bonds that boost the hydrogel's ability to self-repair and maintain structural integrity under repeated stress.The dataset includes performance metrics for multiple formulations, with BISS concentrations set at 0.4, 0.7, and 1 mol%, and Al3+ contents ranging from 0 to 1.5 wt%. Notably, the hydrogel with 0.7 mol% BISS and 1 wt% Al3+ (pAcOrn–0.7%BISS/1%Al3+) showed outstanding properties: over 900% elongation, breaking strength near 9.5 kPa, and the ability to recover 57.4% of its stress within just 2 minutes after damage. These characteristics were further enhanced using laser irradiation to activate and tune the Al3+–amino acid interactions.In addition to mechanical resilience, this hydrogel demonstrated promising electrical responsiveness. It showed quick and consistent signal behavior during bending, with response and recovery times of 1200 ms and 1300 ms, respectively. The electrical output correlated linearly with applied strain (R2 = 0.992), and the presence of Al3+ significantly improved the gauge factor, making this system a strong candidate for applications in motion tracking and flexible strain sensors.Altogether, this dataset offers helpful information regarding the role of aluminum ions in designing tunable, self-healing, and responsive hydrogels. It includes mechanical testing data, recovery performance, strain sensing output, and formulation parameters for each variant.</p
Languages of Caquetá-Putumayo database
No full textThis dataset is based on grammatical data from seven Indigenous languages spoken in the Caquetá-Putumayo River Basins of Colombia. The languages belong to three language families—Witotoan (Murui-Muina, Ocaina, Nonuya), Boran (Bora, Muinane), and Arawak (Resígaro)—as well as one linguistic isolate, Andoke. Initially based on data from the Hunter-Gatherer Language Database (HGDL), the dataset has since been expanded and restructured using a set of grammatical categories specifically designed to capture key morphosyntactic features of languages from Northwest Amazonia.The dataset was collected and verified by linguist Dr. Katarzyna I. Wojtylak through a rigorous process of cross-checking against existing linguistic literature, her own field expertise, and consultations with specialists in these languages. While the initial data drew from the HGDL framework, it became evident that additional grammatical categories were necessary to more accurately represent the structures of the region’s languages. As a result, a new typological framework was developed, incorporating features particularly relevant to the grammatical description of Northwest Amazonian languages, such as classifier systems, evidentiality, switch reference, and complex predicates.The dataset is organized into a hierarchical structure reflecting these expanded grammatical categories. Each feature is systematically coded as present, absent, or unknown, allowing for comparative analysis both within and across language families. By distinguishing inherited traits from contact-induced features, this dataset provides insights into the historical and contemporary dynamics of grammatical structures in this multilingual region.Through both quantitative and qualitative analyses, the dataset contributes to the study of areal patterns, grammatical diffusion, and the interplay between genealogical inheritance and language contact. It offers a valuable resource for typologists, historical linguists, and researchers focusing on Amazonian languages.The dataset is structured into CSV files, categorizing each language’s grammatical features in a format suitable for comparative linguistic research. Available under a CC BY license, this dataset represents a significant contribution to the understanding of grammatical diversity in Northwest Amazonia.</p
Analiza różnic transkryptomu perycytów CD146+ izolowanych z myszy szczepu dzikiego i myszy szczepu mdx
No full textProjekt dotyczy zbadania różnic w profilu ekspresji genów w perycytach syntezujących marker CD146 (perycyty CD146+) izolowanych z mięśni szkieletowych kończyn tylnych myszy szczepu dzikiego (WT) oraz mięśni myszy szczepu mdx (mdx), które w badaniach podstawowych służą za model ludzkiej choroby – dystrofii mięśniowej Duchenne’a. Komórki wyizolowano z mięśni szkieletowych myszy WT oraz mdx, sortowano z wykorzystaniem kolumn magnetycznych aby wzbogacić populację komórek CD146+. Po 5 dniach hodowli komórki zebrano i wyizolowano całkowite RNA. Wykonano analizę NGS (Next Generation Sequencing Core Facility, Centrum Nowych Technologii).Dane z wysokoprzepustowego sekwencjonowania występują w postaci:„rawCounts” - pliku z surowymi danymi (.txt)„comparsion” - list zidentyfikowanych taranskryptów (.xlsx)"MDX_1_R1.001" - wyniki sekwencjonowania - forward (.fastq)"MDX_1_R2.001" - wyniki sekwencjonowania - reverse (.fastq)"WT_1_R1.001" - wyniki sekwencjonowania - forward (.fastq)"WT_1_R2.001" - wyniki sekwencjonowania - reverse (.fastq)Dla poszczególnych wariantów eksperymentu:WT – perycyty CD146+ izolowane z mięśni szkieletowych myszy szczepu dzikiegomdx – perycyty CD146+ izolowane z mięśni szkieletowych myszy szczepu mdx.The project aims to investigate differences in the gene expression profile of pericytes expressing the CD146 marker (CD146+ pericytes) isolated from the skeletal muscles of wild-type (WT) mice and mdx mice, which serve as a fundamental research model for Duchenne muscular dystrophy.Pericytes were isolated from the skeletal muscles of WT and mdx mice and subsequently enriched for the CD146+ population using magnetic column sorting. After five days of in vitro culture, cells were harvested, and total RNA was extracted. Next-generation sequencing (NGS) was performed at the Next Generation Sequencing Core Facility, Center for New Technologies.The high-throughput sequencing data are available in the following formats:"rawCounts" – a text file (.txt) containing raw sequencing data“comparison" – an Excel file (.xlsx) listing identified transcriptsThese datasets correspond to the experimental conditions:WT – CD146+ pericytes isolated from the skeletal muscles of wild-type micemdx – CD146+ pericytes isolated from the skeletal muscles of mdx mice."MDX_1_R1.001" - sequencing results - forward (.fastq)"MDX_1_R2.001" - sequencing results - reverse (.fastq)"WT_1_R1.001" - sequencing results - forward (.fastq)"WT_1_R2.001" - sequencing results - reverse (.fastq)</p
Lipid membrane systems, parameter and topology files used in molecular dynamics simulations concerning influence of lipid membrane curvature on the architecture of lipid membranes described by different force fields.
No full textDataset for publication: “Exploring the Properties of Curved Lipid Membranes: Comparative Analysis of Atomistic and Coarse-Grained Force Fields”.Zip file contains folders (separate folders for each considered force fields: Martini3, Martini2, Amber Lipid21, Charmm36m) in which input files for molecular dynamics simulations of considered curved lipid systems can be found. In folders there are files that are needed to reproduce molecular dynamics simulations described in the related publication.files with simulated system structure (.gro file) - containing water, ions and curved (sinusoidal in shape) lipid membrane composed of POPC moleculesfiles with molecular dynamics parameters (*mdp files) necessary to conduct MD simulations with a specifically curated parameters, that allow for the curved shape to be maintainedfiles containing information about topology of the simulated system in specific, chosen force field (toppar/ folder)index file (*ndx) with indexes of the atoms in the simulated systemsAll files can be opened using a text editor.</p
Ludność Warszawy według wykształcenia
No full textDane o strukturze wykształcenia ludności Warszawy w wieku 13 i więcej lat w 2002 i 2021 r. - obliczenia własne na podstawie danych zamawianych w Głównym Urzędzie Statystycznym.Jednym z najbardziej widocznych trendów zmian struktury społecznej Warszawy w ostatnich dziesięcioleciach był znaczący wzrost liczby mieszkańców z wyższym wykształceniem. Podczas gdy w 2002 r. mniej niż co czwarty mieszkaniec Warszawy miał dyplom ukończenia wyższej uczelni, obecnie może się nim pochwalić co drugi warszawiak. Wynika to z popytu na wykwalifikowanych pracowników ze strony sektora zaawansowanych usług biznesowych, który zatrudnia obecnie ponad 30% pracujących w stolicy. </p
Orthogonal photoswitching in a porous organic framework
No full textThis dataset contains all raw data used to generate Figures 2–5 in the article titled "Orthogonal Photoswitching in a Porous Organic Framework".The dataset contains raw data of: DRIFT spectrum of PSF;13C-1H CP MAS spectra of PSF;N2 sorption isotherm collected at 77 K and the pore size distribution of PSF;uv-vis spectra of reversible photoswitching of switch S1 in solution;uv-vis spectra of orthogonal photoswitching in PSF (solid state);pictures of color change of PSF; 19F-13C CP MAS NMR spectra of PSF;N2 adsorption isotherms collected at 77 K of PSF before and after photoisomerisation;CO2 adsorption isotherms collected at 273 K and 293 K of PSF before and after photoisomertisation.File Types and Formats:'.csv' – raw data from uv-vis, DRIFT, FT-IR and BET measurements. '.csv', files can be opened with any text editor (e.g. Notepad) or spreadsheet editor (e.q. Microsoft Excel).'.jpg' - raw pictures of PSF material before and after photoisomerisation. '.png' files are compatible with any image viewer.'.txt', '.info', '.par', '.png' – raw data from CP MAS NMR measurements. '.txt', '.info' and '.par', files can be opened with any text editor (e.g. Notepad)No special software is required to read '.csv', '.jpg' files. To open raw NMR spectra, lease use for example MestReNova.</p
Raw XRD data from: Fe-nodules from the southern Baltic Sea. Morphology, mineralogy and geochemistry
No full textRaw XRD data from research paper "Fe-nodules from the southern Baltic Sea: morphology, mineralogy and geochemistry". These are raw *.xrdml files which may be opened by notepad (in Windows OS) or Profex software (open-source).For the analysis of the samples, X-ray diffraction in the Bragg-Brentano configuration was employed using an X'Pert PRO MPD diffractometer (PANalytical B.V., Netherlands) equipped with a cobalt anode tube and an iron filter. The samples were dried, crushed, and ground into powder (90% of particles ≤ 80 μm) using an agate mortar and pestle. The powdered samples were pressed into thin pellets using a back-loading method. Diffractograms were recorded over the angular range of 4° to 78° (2θ) using Co Kα radiation, with a voltage of 40 kV and a current of 30 mA, at a measurement step size of 0.026°/min and a step time of 2 seconds. The total analysis duration was 4 hours.Dane pierwotne z metody dyfrakcji rentgenowskiej z próbek omawianych w artykule: "Fe-nodules from the southern Baltic Sea: morphology, mineralogy and geochemistry". Pliki w formacie *.xrdml, możliwość wglądu za pomocą notatnika w sysytemie Windows lub programu Profex (open-source).W celu analizy próbek zastosowano dyfrakcję rentgenowską w układzie Bragg-Brentano dyfraktometrze X’Pert PRO MPD (PANalytical B.V., Holandia) wyposażonym w lampę z anodą kobaltową oraz filtr żelazowy. Próbki osuszono, rozkruszono i zmielono na proszek (90% cząstek ≤ 80 μm) przy użyciu moździerza i tłuczka z agatu. Próbki sproszkowane zostały sprasowane w cienkie płytki metodą załadunku od tyłu. Dyfraktogramy rejestrowano w zakresie kątowym od 4 do 78° (2θ) przy użyciu promieniowania Co Kα, napięciu 40 kV i prądzie 30 mA, z krokiem pomiarowym 0,026°/min i czasem pomiaru 2 s/krok. Czas trwania analizy: 4h</p
Polarisation-dependent Raman enhancement in hexagonal boron nitride membranes
No full textThe experimental data presented is related to the article: J Rogoża, J. Binder, K. V. Voronin, I. Niehues, K. Ludwiczak, A. K. Dąbrowska, M. Tokarczyk, R. Bożek, A. Y. Nikitin, R. Hillenbrand, R. Stępniewski, A. Wysmołek “Polarisation-dependent Raman enhancement in hexagonal boron nitride membranes” Nanoscale 17, 3053 (2025)Raman spectroscopy is a powerful analytical method widely used in many fields of science and applications. However, one of the inherent issues of this method is a low signal-to-noise ratio for ultrathin and two-dimensional (2D) materials. To overcome this problem, techniques like surface-enhanced Raman spectroscopy (SERS) that rely on nanometer scale metallic particles are commonly employed. Here, we demonstrate a different approach that is based on a microcavity structure consisting of a hexagonal boron nitride (h-BN) membrane spanning over an air-filled trench in germanium. In this structure, the h-BN membrane is an integral part of the cavity and, at the same time, shows an about 10-fold, polarisation-dependent h-BN Raman signal enhancement. With h-BN being transparent, flat, and chemically robust, it provides an excellent interface between the cavity and adjacent materials. We show that the Raman enhancement is also present for graphene layers transferred on top of the h-BN membrane, which proves that our approach can be extended to van der Waals heterostructures. The observed polarisation and position-dependent enhancements are in very good agreement with numerical simulations of the electric field intensity of the cavity. These results, together with the presented facile h-BN membrane fabrication process, which does not require any lithographic methods, open up new possibilities for enhancing Raman signals of 2D crystals without the need for metal particles.Files:Fig2The file names refer to the polarization of the laser parallel to the X or Y axis.The measurements were conducted using an inVia™ confocal Raman microscope equipped with a 532 nm, 30 mW laser. A 100x lens was used. The exposure time was 3 seconds at 100% laser power for both measurements.Fig3The terms "Parallel" and "Perpendicular" in the file names refer to the polarization of the laser with respect to the edge of the trench.The measurements were conducted using an inVia™ confocal Raman microscope equipped with a 532 nm, 30 mW laser. A 100x lens was used. The exposure time was 5 seconds at 100% laser power for both measurements.Fig4The measurements were conducted using an inVia™ confocal Raman microscope equipped with a 532 nm, 30 mW laser. A 100x lens was used. The exposure time was 5 seconds at 100% laser power for both measurements.</p
Exploring the functional and immunological diversity of the fatty acid-binding protein (FABP) family in Fasciola hepatica
No full textThis study aimed to investigate the role of Fasciola hepatica fatty acid-binding proteins (FhFABPs). All seven FhFABP isoforms were successfully cloned, and six were recombinantly expressed using a yeast expression system. To assess the functions of individual isoforms, various methods were employed, including real-time PCR, ELISA, ANS displacement assays, and cell culture experiments using monocyte-derived dendritic cells (moDCs) treated with FhFABPs. A quantitative analysis of fabp isoform gene expression across different developmental stages was performed using real-time PCR. RNA isolated from eggs, metacercariae, newly excysted juveniles (NEJs), and adult worms served as templates, with isoform-specific primers used for each FABP (Figure3_Figure4). Sheep sera collected from animals experimentally challenged with Fasciola hepatica were used to assess IgG antibody responses against FhFABPs using the ELISA method (Figure5). An ANS displacement assay using selected fatty acids was also conducted to evaluate the binding affinity of fatty acids to FhFABPs (Figure6). In the supernatants from cell cultures treated with FhFABPs, cytokine and chemokine levels were measured using ELISA (Figure7), while cell surface markers were analyzed by flow cytometry (FigureS4). Quantitative gene expression analysis revealed distinct, stage-specific expression patterns, with the highest levels observed in adult flukes. Functional assays demonstrated isoform-specific variations in fatty acid binding, indicating potential adaptations to host environments. Immunological evaluations highlighted the variable immunogenicity of FhFABPs and their capacity to modulate human dendritic cell responses in an isoform-dependent manner. Collectively, these findings underscore the critical roles of FhFABPs in nutrient acquisition, immune modulation, and parasite survival. Their involvement in pathogenesis and immune evasion positions them as promising candidates for the development of vaccines, diagnostic tools, and novel immunomodulatory therapies.</p
Electrochemical properties of gold electrode modified for the future studies of protein immobilization
No full textThe data includes capacitance curves and charge density for various stages of gold electrode modification, intended to prepare the surface for directional immobilization of transmembrane proteins.The curves and charge density data help track and confirm the subsequent stages of gold electrode modification and their effectiveness.</p