Repositório de Dados de Pesquisa da Unicamp (Universidade Estadual de Campinas)
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1611 research outputs found
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Identification of the molecular basis of Menière's Disease in Brazilian cohort
No full textThis dataset comprises the complete molecular and structural findings from the doctoral thesis "Identification of the molecular basis of Meniere's Disease," representing the first comprehensive whole exome sequencing (WES) profiling of a Brazilian patient cohort diagnosed with Ménière's Disease. Generated through a collaborative effort between the Laboratory of Human Molecular Genetics at CBMEG/UNICAMP and the Meniere's Disease Neuroscience Laboratory at the Kolling Institute, University of Sydney, the dataset includes three main components: (1) WES data from 22 patients analyzed using the Nextera Rapid Exome Enrichment Kit on the HiSeqTM 2500 platform, which identified variants of interest in 13 genes (OTOG, PCDH15, USH1G, ADGRV1, ESRRB, CDH23, AQP6, KCNH2, TNFRSF13B, SDHA, HRH4, ADD1, SLC25A35, HMX2) across 11 patients; (2) molecular screening results for the intergenic variant rs4947296, a trans-expression quantitative trait locus on chromosome 6 previously associated with bilateral MD and shown to regulate genes in the TWEAK/Fn14 pathway, potentially linking the disease to autoimmune response mechanisms; and (3) three-dimensional structural models of wild-type and mutated proteins corresponding to the identified genetic variants, generated using Modeller, Swiss-Model, and AlphaFold, with structural analysis performed in PyMOL and stability predictions via DynaMut2 to elucidate the potential structural impacts of these variants
Dados experimentais sobre estudos funcionais e busca por novos inibidores de prolil-tRNA sintetase de Klebsiella pneumoniae
No full textEsse conjunto de dados se refere a experimentos de purificação, SEC-MALS, ensaios cinéticos de inibição, high throughput screening, ensaios fenotípicos em células bacterianas Klebsiella pneumoniae (ATCC BAA-1705 e ATCC BAA-1706), Escherichia coli (ATCC 25922 e ATCC 35218), B. cenocepacia (ATCC BAA-245) e Xanthomonas citri (cepa 306) e de viabilidade em células de mamífero, linhagem HepG2.
Os dados não podem ser disponibilizados por questões de proteção intelectual, pois o manuscrito ainda está em processo de aceitação. Para mais informações, contatar os responsáveis do depósit
An exploratory study on new perspectives in combinatorial problems
No full textForam utilizados dois conjuntos de dados nesta dissertação, ambos voltados à avaliação de métodos de otimização combinatória. O primeiro conjunto refere-se ao Problema do Caixeiro Viajante (TSP) e consiste nas instâncias para a comparação entre os modelos MTZ e o modelo proposto P-MTZ, considerando como métricas o tempo de execução e o GAP de otimalidade. Estas instâncias correspondem às matrizes de distâncias, calculadas usando os conjuntos de dados fornecidos pelo dataset TSPLIB (https://doi.org/10.1287/ijoc.3.4.376)
O segundo conjunto de dados está associado ao Problema de Atribuição de Atraques (BAP) e contempla as instâncias para uma análise comparativa entre as meta-heurísticas Particle Swarm Optimization (PSO) e Escape Strategies Algorithm (ESSA), com foco no desempenho e na qualidade das soluções obtidas. As instâncias foram tomadas do trabalho de Cordeau et al 2025. (DOI: 10.1287/trsc.1050.0120
Replication Data for: Dados relativos à carreira do magistério primário estadual paulista, presentes no Decreto Estadual no 5884/1933 e no Decreto Estadual no 17.698/1947
No full textDocumento contendo dados a respeito da legislação sobre a carreira docente utilizados na tese intitulada "A consolidação da profissão docente em São Paulo: aspectos da carreira do magistério paulista entre 1933 e 1947"
Dados sobre técnicas anestésicas realizadas em gestantes obesas com IMC ≥ 40 para operação cesariana
No full textDados anonimizados de pacientes obesas submetidas a operação cesariana coletados por meio de prontuários de paciente do CAISM (Centro de Atenção Integral à Saúde da Mulher). Dados do período de janeiro de 2018 a dezembro de 2024. IMC>=40. Dados levantados para trabalho de conclusão de curso no Programa de Residência Medica em Anestesiologia da UNICAMP
Conjunto de dados acadêmicos dos alunos da FEEC
No full textConjunto de dados contendo informações acadêmicas dos alunos da FEEC no período de 2005 a 2024.
Os dados não podem ser disponibilizados em respeito à LGPD, por se tratar de informações pessoais
Comparative analysis of resource usage and energy consumption for three different models of FPGA
No full textThis repository contains the experimental dataset and analysis scripts from a study on approximate hardware accelerators using adders from the EvoApprox library. The work investigates power dissipation and resource utilization (LUT and flip-flop usage) for FPGA implementations on Microchip PolarFire, Digilent Arty A7-35T, and Xilinx Alveo U250 platforms, and compares them with ASIC characterizations using a Sobel image processing accelerator.
The study evaluates the transferability of ASIC-based characterizations to FPGA designs and analyzes the asymmetry of resource and power variations across platforms. Statistical validation was performed using One-Way ANOVA, Tukey’s post-hoc test, and Bartlett’s test. Results indicate that approximate designs in ASIC and FPGA can be statistically similar depending on the application, with negligible differences in power consumption and, in many cases, also in area.
The repository provides the complete dataset, Python scripts for data processing and visualization, statistical analysis code, and CSV exports of all experimental results, supporting reproducibility and further research in approximate computing and hardware acceleration
Experimental datasets related to the development and characterization of nanostructured polysaccharide-based biomaterials for 3D bioprinting applications
No full textThis dataset includes experimental data generated during a doctoral research project focused on polysaccharide-based hydrogels reinforced with cellulose nanocrystals (CNC) for extrusion-based 3D bioprinting applications aimed at cartilage tissue engineering.
The data are organized into the following five experimental series:
1) Formulation selection: Rheological data (viscosity and oscillatory tests), qualitative stability assessment by inversion tube tests, and extrusion-based 3D printing assays used to evaluate printability and shape fidelity.
2) Sterilization analysis: Comparative rheological data before and after sterilization, microstructural analyses by scanning electron microscopy (SEM), mechanical compression tests, and thermal characterization by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC).
3) Crosslinking analysis: Long-term stability studies in cell culture medium and rheological characterization to assess the effects of crosslinking on material integrity and viscoelastic properties.
4) Biocompatibility assessment: In vitro cytocompatibility data obtained from MTT assays performed with hydrogel formulations and crosslinking agents, and spheroid fusion assays designed to evaluate spheroid behavior and fusion capacity in direct contact with the hydrogels.
5) 3D bioprinting: Data related to extrusion-based 3D bioprinting of cell-laden constructs, including post-printing cell viability and metabolic cell activity measurement.
Data availability is restricted due to intellectual property protection. For additional information, please contact the responsible authors
Enhanced catalytic ozonation using MIL-53(Fe) MOF and CS@MIL-53(Fe) composite beads: a comparative evaluation for organic contaminant removal
No full textCAMPAROTTO, NATÁLIA GABRIELE ; MALVESTITI, JACQUELINE A. ; DE SOUSA, IURE BERNARDINO ; FOKOUE, HAROLD H. ; DANTAS, RENATO FALCÃO ; VIEIRA, MELISSA GURGEL ADEODATO ; PREDIGER, PATRÍCIA . Enhanced catalytic ozonation using MIL-53(Fe) MOF and CS@MIL-53(Fe) composite beads: A comparative evaluation for organic contaminant removal. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 2025, p. 119522-119535, 202
Replication data for: EVDura - electric vehicle battery durability prognostics framework
No full textEVDura reúne scripts, notebooks e planilhas da dissertação de mestrado (FEEC-UNICAMP) sobre prognóstico de durabilidade de baterias Li-íon em veículos elétricos baseado em perfil de uso.
O fluxo separa (estimadores/parametrização) de (simulação de cenários).
A parametrização usa dados laboratoriais (NASA) e o prognóstico é testado com perfis de condução reais (EVERLASTING), gerando SoH/RUL com incerteza considerada.
Inclui código para reproduzir R²/RMSE, figuras e artefatos citados na dissertação.
Os dados associados a esta dissertação estão sob embargo temporário por questões de proteção intelectual.
Eles serão disponibilizados futuramente através do Zenodo.
Para mais informações, favor entrar em contato com os responsáveis pelo depósito.
EVDura brings together scripts, notebooks, and spreadsheets from the master’s thesis (FEEC-UNICAMP) on prognostics of Li-ion battery durability in electric vehicles based on usage profile.
The pipeline decouples (estimators/parameterization) from (scenario simulation).
Parameterization relies on laboratory data (NASA), and prognostics is evaluated with real driving profiles (EVERLASTING), producing SoH/RUL with uncertainty quantification.
It includes code to reproduce R²/RMSE, figures, and artifacts referenced in the thesis.
The data cannot be made available at this time due to intellectual property protection and are under temporary embargo.
They will be released in the future through Zenodo.
For further information, please contact the depositors