Universität Innsbruck - Data Repository
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Absence of measurement- and unraveling-induced entanglement transitions in continuously monitored one-dimensional free fermions
No full text<p>This repository contains the code and data accompanying the paper <em>"Absence of measurement- and unraveling-induced entanglement transitions in continuously monitored one-dimensional free fermions."</em> See <strong>readme.txt</strong> for details about the included files.</p>
Graph-based functional and structural resilience assessment of urban drainage networks
No full text<p>This repository contains Python code implementing a physics-guided, graph-based model for resilience assessment of urban drainage networks, as proposed in the paper:</p>
<p><strong><em>“Functional and structural resilience assessment in urban drainage networks: a physics-guided graph-based surrogate model”</em></strong><br><strong>Authors:</strong> Mohammad Rajabi, Mohsen Hajibabaei, Aun Dastgir, Robert Sitzenfrei</p>
<p> <strong>Overview</strong><br>The model computes:</p>
<ul>
<li>
<p>Resilience to <strong>structural</strong> failures</p>
</li>
<li>
<p>Resilience to <strong>functional</strong> failures</p>
</li>
</ul>
<p>It uses a series of <strong>hydraulically informed graph metrics</strong> for flow routing and, finally, computes resilience using graph-based formulas.</p>
<p> </p>
<div>---</div>
<h2> Files and Folders Structure</h2>
<p>├── Functional_resilience.ipynb # Calculate functional resilience under all block rainfall scenarios<br>├── Functional_resilience_dynamic_rain.ipynb # Calculate functional resilience under all Chicago and Euler Type II rainfall scenarios<br>├── Structural_resilience.ipynb # Calculate structural resilience for single-pipe failure scenarios<br>└── input_network/ # Contains the SWMM input file</p>
<p> </p>
<div>---</div>
<div> </div>
<div> </div>
<h2> Contact</h2>
<div>For questions, collaborations, or feedback, please contact: </div>
<div> <a href="mailto:[email protected]">[email protected]</a></div>
<p> </p>
Supplementary Material for Enzyme-responsive nanoparticles: enhancing the ability of endolysins to eradicate Staphylococcus aureus biofilm
No full text<h2>Description</h2>
<p>Stimuli-responsive nanomaterials show promise in eradicating <em>Staphylococcus aureus</em> biofilm from implants. Peptidoglycan hydrolases (PGHs) are cationic antimicrobials that can be bioengineered to improve the targeting of persisters and drug-resistant bacteria. However, these molecules can be degraded before reaching the target and/or present limited efficacy against biofilm. Therefore, there is an urgent need to improve their potency. Herein, PGH–polyphosphate nanoparticles (PGH–PP NPs) are formed by ionotropic gelation between cationic PGHs and anionic polyphosphate, with the aim of protecting PHGs and delivering them at the target site triggered by alkaline phosphatase (AP) from <em>S. aureus</em> biofilm. Optimized conditions for obtaining M23–PP NPs and GH15–PP NPs are presented. Size, zeta potential, and transmission electron microscopy imaging confirm the nanoscale size. The system demonstrates outstanding performance, as evidenced by a dramatic reduction in PGHs’ minimum inhibitory concentration and minimum bactericidal concentration, together with protection against proteolytic effects, storage stability, and cytotoxicity towards the Caco-2 and HeLa cell lines. Time-kill experiments show the great potential of these negatively charged delivery systems in overcoming the staphylococcal biofilm barrier. Efficacy under conditions inhibiting AP proves the enzyme-triggered delivery of PGHs. The enzyme-responsive PGH–PP NPs significantly enhance the effectiveness of PGHs against bacteria residing in biofilm, offering a promising strategy for eradicating <em>S. aureus</em> biofilm.</p>
<h3>Context and methodology</h3>
<ul>
<li>This dataset was created on the frame of NanoBioRS project European Union's Horizon 2020 Research and Innovation Programme under Marie Skłodowska-Curie IF [NanoBioRS-101025065]. </li>
<li>This dataset corresponds to raw data underlying the publication Enzyme-responsive nanoparticles: enhancing the ability of endolysins to eradicate Staphylococcus aureus biofilm</li>
<li>This dataset was generated through experimental work focused on the development and characterization of drug delivery systems, and the effect of <span>such delivery systems on the viability of staphylococcal biofilm triggered by alkaline phosphatase</span></li>
</ul>
<h3>Technical details</h3>
<ul>
<li>For naming the samples comprising peptidoglycan hydrolases (PGH) coated with polyphosphate (PP), a logical system was applied and was maintained across all the publications related with this dataset. </li>
<li>This dataset can be opened using Microsoft Excel, a part of the Microsoft Office suite</li>
<li>This dataset was published and is associated to a DOI</li>
</ul>
<h3>Further details</h3>
<ul>
<li>For further reference, please read Enzyme-Responsive Nanoparticles: Enhancing the Ability of Endolysins to Eradicate Staphylococcus aureus Biofilm</li>
</ul>
MS_Eclipse_2025_January
No full text<p><strong>Eclipse + Vanquish Neo </strong> <br>RLI02AA<br>TKI02BC<br>TKI04BL<br>MHO03CF - Bereuter - full data set - 120 samples<br>Standards</p>
<p><strong>Eclipse + ICS6000 </strong> <br>MHO03CJ<br>MHO03DH<br>RLI01AG<br>Standards</p>
Slavia Tirolenis
No full text<h2>About</h2>
<p>This upload features the data set collected during the Slavia Tirolensis Project led and executed by Emanuel Klotz (LFU Innsbruck) and funded by the FWF.</p>
<h3>Context and methodology</h3>
<p>The goal of the project was to collect and etymologise Slavic place names in Eastern Tirol.</p>
<p>The data collection comprises</p>
<ul>
<li>named objects</li>
<li>their geographical position</li>
<li>possible etymologies (including obsolete or improbrobable suggestions)</li>
<li>evidence of the names in historical records</li>
<li>local pronunciation as IPA transcripts and audio files</li>
<li>pictures of the objects </li>
<li>possible "namesakes" outside Tirol (names from Slovenia, Poland, Czechia etc. that likely have the same origin as a given name in Eastern Tirol)</li>
</ul>
<p>The purpose of the data is to be visualised on a map-based platform open for the public.</p>
<p>A detailed explanation of the data, their function and structure is provided in the readme.pdf attached to the data set. </p>
<h3>Technical details</h3>
<ul>
<li>Database provided in .json, .db and .xml</li>
<li>Documentation on the data structure in .pdf (German)</li>
</ul>
<h3>Additional Information</h3>
<p>Web platform: <a href="https://explore-research.uibk.ac.at/p/slavia-tirolensis/" target="_blank" rel="noopener">https://explore-research.uibk.ac.at/p/slavia-tirolensis/ </a>(with further information on methodology).</p>
Thiolated Hyaluronic Acid: A Gateway for Targeted Killing of Staphylococcus aureus on the Race for Surface Colonization
No full text<p>Thiolated Hyaluronic Acid: A Gateway for Targeted Killing of Staphylococcus aureus on the Race for Surface Colonization. Article published in Advanced Health Care Materials. Wiley.</p>
Data archive of "Elucidating the role of NaCl in the on-surface synthesis of conjugated azaacene polymers on Au(111)"
No full text<p>STM: Scanning tunneling microscopy (STM) and atomic force micrscopy (AFM) raw data. The files can be loaded, for example, with the opensource software "Gwyddion" (https://gwyddion.net/).</p>
<p>XPS: X-ray Photoelectron Spectroscopy data and Igor Pro routine to load and visualize the data.</p>