Hatay Mustafa Kemal Üniversitesi Akademik Veri Yönetim Sistemi
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Urinary calcium-to-citrate ratio predicts kidney stone risk in children under the age of two years
No full textBackground The urinary calcium-to-citrate (Ca/Cit) ratio has emerged as a useful indicator of lithogenic risk in older children; however, no reference data exist for infants and toddlers. This study aimed to evaluate whether the spot Ca/Cit ratio can distinguish stone-forming from non-stone-forming children under 24 months of age and to assess its diagnostic performance compared with conventional urinary markers. Methods This retrospective single-center study included 181 children aged 1-24 months who underwent metabolic evaluation and ultrasonography at their first presentation to a tertiary pediatric nephrology clinic between 2012 and 2024. Based on urinary calcium excretion and ultrasonographic findings, participants were categorized as normocalciuric stone-free controls (n = 57), hypercalciuric stone-formers (n = 29), or non-hypercalciuric stone-formers (n = 95). Spot urine calcium, citrate, and related biochemical ratios were analyzed. The diagnostic accuracy of the Ca/Cit ratio for predicting stones was assessed using receiver operating characteristic (ROC) analysis. Results The Ca/Cit ratio differed significantly across groups, with the highest levels observed in hypercalciuric stone-formers (0.46 mg/mg) compared with controls (0.17 mg/mg; p 0.23 mg/mg (approximate to 1.10 mmol/mmol) demonstrated moderate diagnostic ability for stone detection (AUC 0.695; 95% CI 0.613-0.785), yielding 66.1% sensitivity and 63.2% specificity. Age showed no meaningful correlation with Ca/Cit values. Normocalciuric stone-free children provided an age-appropriate reference distribution for Ca/Cit ratios. Conclusions In infants and toddlers evaluated for suspected urinary stone disease, the Ca/Cit ratio offers moderate discriminatory power and may serve as a practical adjunctive marker of stone risk. A ratio > 0.23 mg/mg (approximate to 1.10 mmol/mmol) appears to indicate increased lithogenic potential. Larger prospective studies are needed to validate reference intervals and refine clinically applicable cut-off values for this young age group
DEPREM BÖLGESİNDE YAŞAYAN ORTAOKUL ÖĞRENCİLERİNİN BESİN GÜVENLİĞİ DAVRANIŞI ile SAĞLIKLI BESLENME ÖZYETERLİLİĞİ, TUTUM ve DAVRANIŞLARININ İNCELENMESİ
No full textDoğal afetler, can ve mal kayıplarının yanı sıra ekonomik, sosyal ve çevresel açılardan ciddi zararlara yol açmaktadır. Afetzedeler için en temel ve acil ihtiyaçlardan biri barınma ve beslenmedir. Özellikle büyüme ve gelişme çağındaki çocukların beslenme durumu, afet sonrası toparlanma süreci ve gelecekteki sağlık durumları açısından kritik önem taşımaktadır. Bu çalışma, 6 Şubat 2023 tarihinde meydana gelen depremin ardından Hatay’ın Antakya ilçesinde öğrenim gören ortaokul öğrencilerinin besin güvenliği davranışları ile sağlıklı beslenmeye ilişkin özyeterlilik, tutum ve davranışlarını incelemek amacıyla yürütülmüştür. Araştırma betimsel tarama modeliyle gerçekleştirilmiş olup çalışma grubunu 349 ortaokul öğrencisi oluşturmuştur. Veriler; Besin Güvenliği Davranış Ölçeği, Beslenme Öz-Yeterlik Ölçeği, Beslenme Tutum Ölçeği ve Beslenme Davranış Ölçeği kullanılarak toplanmıştır. Normallik analizleri sonucunda verilerin normal dağılım göstermediği belirlenmiş ve analizlerde Mann–Whitney U ile Kruskal–Wallis testlerinden yararlanılmıştır. Araştırma bulguları, öğrencilerin beslenme tutumlarının besin güvenliği bilgisi, sağlıklı beslenme bilgisi ve besin güvenliği kurallarına dikkat etme durumlarına göre istatistiksel olarak anlamlı biçimde farklılaştığını göstermiştir. Ayrıca enkazda kalma durumu ile beslenme tutumu arasında anlamlı bir ilişki olduğu belirlenmiştir. Beslenme davranışları açısından sosyodemografik değişkenlere göre anlamlı bir farklılık bulunmamıştır. Beslenme öz-yeterlilik algısının sağlık durumuna göre farklılaştığı ve kendini sağlıklı olarak değerlendiren öğrencilerin öz-yeterlilik puanlarının daha yüksek olduğu belirlenmiştir. Besin güvenliği davranışları açısından besin güvenliği bilgisi değişkeni anlamlı bulunurken, davranış alt boyutları bakımından anlamlı bir farklılık saptanmamıştır. Çalışma sonuçları, afet sonrası dönemde öğrencilerin besin güvenliğine ilişkin farkındalıklarının gelişmiş olmasına karşın bu farkındalığın beslenme davranışlarına sınırlı ölçüde yansıdığını göstermektedir. Afet bölgelerinde okul, aile ve toplum temelli beslenme ve besin güvenliği uygulamalarının güçlendirilmesi gerektiği sonucuna ulaşılmıştır. </p
Responsiveness, Minimal Detectable Change, and Minimal Clinically Important Difference of the Turkish Version of the 8-item Overactive Bladder Questionnaire
No full textIntroduction and Hypothesis: The 8-item Overactive Bladder Questionnaire (OAB-V8) is a readily available instrument for assessing overactive bladder (OAB) symptoms in clinical and research settings. Despite its established validity in Turkish, its psychometric property remains unevaluated. This study aimed to determine the responsiveness, minimal detectable change (MDC), and minimal clinically important difference (MCID) of the Turkish version of the OAB-V8. Methods: This retrospective study consisted of 160 women (age 47.49 ± 12.07 years) with OAB who completed a standardized, guideline-adherent 8-week pelvic floor muscle training. The OAB-V8 was administered pre- and post-training. The responsiveness of the OAB-V8 was assessed using the Wilcoxon signed-rank test, standardized response means (SRMs), and effect sizes (ESs). The MDC was calculated at the 95% confidence level. Receiver operating characteristic (ROC) analysis was used to determine the MCID, maximizing both sensitivity and specificity. Results: The responsiveness of the Turkish version of the OAB-V8 was excellent (ES = 1.57, SRM = 1.56, p < 0.001). The MDC and MCID values were 12.97 and 12.50, respectively. The ROC analysis demonstrated excellent discriminative ability, with an area under the curve of 0.99 (sensitivity 98.0%, specificity 90.0%). Conclusions: The main findings of this study confirm that the OAB-V8 demonstrated excellent responsiveness and discriminative ability, making it an effective tool for assessing symptoms in women with OAB. Clinicians can confidently use the Turkish version of the OAB-V8 scale to not only monitor treatment efficacy but also to determine whether the observed changes are both statistically significant and clinically relevant for the patient
Production of two Kımı pickles using the whey and vinegar as fermentation media and determination of bacterial and fungal microbiota, antibacterial and antibiofilm activities of Kımı pickles
No full textPlants can be used for different purposes, such as food, tea, and spices or for healing against various diseases. In this study, two different Kımı pickles, such as fermented with vinegar (SKT) and fermented with whey (PASKT), were produced. The antibacterial properties of both Kımı pickles were determined by MIC, MBC, and MTC and antibiofilm activity was determined by the crystal violet method. The bacterial microbiota of the Kımı pickle samples were determined by 16S metagenom analysis and the fungal microbiota by ITS metagenom analysis. As a result, the plant known as Kımı was systematically determined as Bunium cylindricum (Boiss. & Hohem.) Drude. PASKT exhibited the highest antibacterial activity against Bacillus licheniformis ATCC 14580, Klebsiella pneumoniae ATCC 33495, and Staphylococcus aureus ATCC 6538, while Staphylococcus aureus ATCC 6538 was the most sensitive to SKT. PASKT inhibited biofilm formation at a higher rate against Escherichia coli ATCC 8739 and Bacillus licheniformis ATCC 14580, while SKT exhibited higher antibiofilm activity against Klebsiella pneumoniae ATCC 33495 and Bacillus licheniformis ATCC 14580. The dominant bacterial genus in the PASKT was Bacteroides, whereas in the SKT it was Latilactobacillus. Dipodascus was the dominant genus in the PASKT fungal microbiota, while Penicillium was the dominant genus in the SKT fungal microbiota. In this study, whey was used as the fermentation medium for PASKT production. This has the potential to create an alternative for the utilization of whey, which is rich in nutrient content but is considered waste and can cause environmental pollution
Hatay ilinde pamuk çeşitleri üzerinde yaprak pireleri [Empoasca decipiens (paoli) ve Asymmetrasca decedens (paoli) (hemiptera: cicadellidae)]'nin popülasyon yoğunluğunun bitkinin fenolojik dönemlerine göre belirlenmesi
No full textWho Is Most at Risk? Exploring the Prevalence of Psychiatric Comorbidities in Children With Intellectual Disability by Age, Sex, Severity, and Socioeconomic Background
No full textBackground: Data on psychiatric comorbidities in children with intellectual disability (ID) across subgroups remain limited. Thus, we aimed to investigate comorbidity prevalence by age, sex, ID severity, and socioeconomic status. Methods: This multicentre, cross-sectional study included 1742 children with ID consecutively recruited from child psychiatry outpatient clinics. Participants were assessed using comprehensive psychiatric interviews, the Strengths and Difficulties Questionnaire, and Clinical Global Impression. Results: Comorbid psychiatric disorders were present in 86.2% of the sample; 24.7% had one, and 61.5% had two or more. The most common diagnoses were ADHD (44.3%), anxiety disorders (40.0%), oppositional defiant disorder (36.7%), and conduct disorder (29.2%). Comorbidity rates were significantly higher in males, adolescents, those with severe ID, and those from higher-income families. Internalising disorders were more common in females; externalising disorders in males and adolescents. Conclusions: Our findings suggest the integration of systematic, developmentally sensitive psychiatric screening into standard clinical care for children with ID
Aksaray İli Şeker Pancarı (Beta vulgaris var. saccharifera L.) Ekim Alanlarında Bulunan Yabancı Ot Türlerinin Yaygınlıkları, Yoğunlukları ve Bazı Bitki Uçucu Yağlarının Allelopatik Etkilerinin Belirlenmesi
No full textThe Mediating Role of Critical Thinking in the Relationship Between Creative Thinking and Reflective Thinking
No full textThis study explores the mediating role of critical thinking (Cri-T) in the relationship between creative thinking (Cre-T) and reflective thinking (RT) among pre-service teachers. Within this scope, the structural equation model (SEM) was employed, involving a total of 504 pre-service teachers from four faculties of education in Türkiye, selected through convenience sampling. The ‘Critical Thinking Scale’, the ‘Reflective Thinking Scale’ and the ‘Creative Thinking Scale’ were used as data collection tools. In the data analysis, correlation analysis, confirmatory factor analysis (CFA) and regression-based mediation analysis via Hayes' PROCESS macro were used. In addition, bootstrap estimates of the indirect effect, beta coefficients, 95% confidence intervals and effect sizes were also calculated. The results indicated strong positive correlations between Cre-T and both RT and Cri-T, and a moderate positive correlation between Cri-T and RT. Furthermore, Cri-T was found to fully mediate the relationship between Cre-T and RT
Quantile spillover connectedness among CO2 emission sources: An empirical analysis in European Union
No full textEnvironmental degradation from carbon dioxide (CO2) emissions intensifies climate challenges, damages ecosystems, and threatens biodiversity. Addressing this concern, this study highlights the quantile connectedness among various sources of CO2 emissions: residential, power, transportation, industrial, domestic, and international aviation, focusing on how interconnectedness varies across different quantiles in the European Union (including the UK) from 1st January 2019 to 30th August 2024. The obtained spillover effects reveal a significant total connectedness within the system. Notably, domestic aviation is identified as the leading contributor of spillover shocks to all other sources, demonstrating its pervasive influence across the CO2 emission network. Furthermore, the transmission of return spillovers is more pronounced in the left and right tails of emissions from residential, transportation, industrial, and domestic aviation sectors, indicating increased interconnectedness during periods of extreme market events. The results specifically show that at lower quantiles, transportation (domestic aviation) serves as a contributor (receiver) of spillover shocks, while at the 90th quantile, domestic aviation becomes the sole contributor of shocks to all other variables, and they switch positions. These insights are crucial for policymakers, as they underline the need for targeted and flexible climate policies that take into account the varying roles of emission sources under different conditions of market volatility. Effective mitigation strategies should therefore take into account the dynamic nature of these interdependencies in order to achieve more resilient and sustainable emission reduction targets
