Hatay Mustafa Kemal Üniversitesi Akademik Veri Yönetim Sistemi
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Understanding the Culinary Gap: Why Artichoke is Missing in Hatay’s Gastronomic Heritage
No full textGlycaemic control and complications in haemodialysis patients: The TURK-HEMODIAB Study
No full textBackground The most common cause of end-stage kidney disease is diabetes mellitus (DM). The most commonly used renal replacement therapy in Turkey and in many countries around the world is haemodialysis (HD). Glycaemia control is important in these populations. In this study we aimed to screen for glycaemic control and complications in a large population of diabetic HD patients in Turkey. Methods A total of 16 043 patients were screened in 253 dialysis centres in Turkey and 5038 diabetic HD patients were included in the study. At participating centres, patients' diabetes history, complications, medications, haemoglobin A1c (HbA1c) and other laboratory data were reviewed and recorded by nephrologists. Results The average age of the patients was 64.0 ± 11.2 years and 56% were male. The mean HbA1c was 7.4 ± 1.5%. Patients were divided into three groups according to the HbA1c level (8%). As the HbA1c levels increased, the mean systolic blood pressure and diastolic blood pressure increased significantly. In addition, as the HbA1c levels increased, the number of patients with coronary artery disease, patients undergoing coronary artery bypass graft surgery and the rate of patients with diabetic retinopathy and vision loss increased. Diabetic foot disease and amputation rates were also higher in the group with poor glycaemic control. The number of patients using intensive or mixed insulin was also higher in the group with high HbA1c levels. In ordinal logistic regression analysis, age significantly decreased and higher body mass index slightly increased the risk of a higher HbA1c. Also, the need for a diabetic diet was greater in those with high HbA1c levels. Conclusion Our study highlights that the target values for diabetic HD patients in Turkey are partially compatible with the 2022 Kidney Disease: Improving Global Outcomes guidelines for diabetes management. Nevertheless, more effort and teamwork are needed to improve patient outcomes
Magnesium-L-theanine complex protects against liver and intestinal damage caused by chronic variable stress
No full textChronic stress can lead to serious health problems, including elevated blood glucose, intestinal dysbiosis, villous shortening, decreased enzyme activity and hepatic steatosis. Here, we investigate the protective effects of the magnesium-L-theanine (Mg-T) combination on chronic variable stress (CVS)-induced liver and intestinal damage. Fifty-six rats were divided into two groups: normal and stressed, and supplemented with different doses of Mg-T (0, 100, 200, and 400 mg/kg). The results showed that CVS-treated rats had reduced body weight, serum insulin levels, magnesium levels, intestinal barrier proteins and nutrient transporters. However, Mg-T supplementation improved these parameters in a dose-dependent manner. Mg-T treatment reduced CVS-induced glucose, corticosterone and triglyceride levels, while alleviating liver and intestinal damage. Histological analysis revealed that Mg-T alleviated CVS-induced intestinal damage, characterized by villus shortening, reduced crypt depth and inflammation. CVS-induced increases in hepatic triglycerides and lipogenic markers (SREBF1, FASN) were attenuated by Mg-T supplementation, while metabolic regulators such as PPARγ and SIRT-1 were upregulated. Moreover, Mg-T restored the expression of intestinal barrier proteins (Claudin-1, Occludin, ZO-1) and mucosal protein (MUC-2). CVS treatment reduced the expression of nutrient transporters (SGLT1, GLUT2) and amino acid carriers; however, Mg-T supplementation increased the protein levels of these markers. Our data demonstrate that Mg-T has significant protective effects against CVS-induced metabolic, hepatic and intestinal disturbances, highlighting its potential as a therapeutic intervention for managing chronic stress-related health problems
Post-earthquake emergency nurse allocation: a human resource management approach based on simulation modeling
No full textImpact of Water Stress on Water-Yield Relations, Oil Yield and Essential Oil Quality of Peppermint (Mentha piperita L.)* Nane'nin (Mentha piperita L.) Su-Verim İlişkileri, Yağ Verimi ve Uçucu Yağ Kalitesine Su Stresinin Etkisi
No full textThis study investigates the effects of different levels of water deficiency on the vegetative, physiological, oil yield, and oil composition characteristics of peppermint (Mentha x piperita L.). The experiment was conducted using a randomized complete block design with four different irrigation levels, three replications, and three pots per replication. The pots were filled with clay-loam soil. The water stress levels were created based on the percentage of the field capacity water amount applied to the pots: 100% (I100-no stress), 75% (I75-mild stress), 50% (I50-moderate stress), and 25% (I25-severe stress). The study measured peppermint’s irrigation water requirements, plant water consumption, water use efficiency, stomatal conductance, plant height, leaf thickness, oil yield, and oil components. Plant water consumption decreased as water stress increased. In the early stages of leafing and flowering, water consumption in the no-stress treatment started at 0.810 L and increased to 3.37 L near harvest. A 1 L increase in irrigation water resulted in a 9 g increase in biomass yield. Water use efficiency (WUE) did not show a parallel trend across the treatments in fresh and dry peppermint. The highest WUE in fresh peppermint was observed under moderate stress at 13.22 g L⁻¹, while in dry peppermint, it was 4.68 g L⁻¹. Stomatal conductance was highest in the no-stress treatment, whereas leaf thickness and plant height were highest under mild stress conditions. The reduction in biomass yield was not directly proportional to the increase in water stress, but severe water stress significantly restricted plant growth. The highest oil yield was observed under severe water stress in both fresh and dry peppermint. The essential oil content in dry peppermint was 294% higher than in fresh peppermint under no stress, 272% higher under mild stress, and increased by 232% and 192% under moderate and severe stress, respectively. Water stress in fresh leaves led to variations in Menthol and Pulegone content, while in dry peppermint, all components except Isomenthone were affected by water stress. In fresh biomass, the highest concentration of Eucalyptol was observed in the no-stress treatment, Menthofuran in mild stress, Limonene and Pulegone in moderate stress, and Menthone and Isomenthone in severe stress
Pharmacophobia, Medication Adherence And Related Factors in Rheumatologic Patients Using Biological Agents
No full textAptamer-integrated nanoplatforms for water safety: a focus on heavy metals, antibiotics, pesticides, and bacterial pathogens
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Oflazoğlu, S., & Doksöz, T. (2025). Agricultural Value Chain Recovery after the 2023 Earthquake: Local Stakeholder Perspectives from Hatay, Turkey.
No full textPerceptions of good death and attitudes toward dignified death and euthanasia among nursing students in Türkiye: a cross-sectional descriptive-correlational study
No full textBackground: Nursing students’ perceptions and attitudes towards death and end-of-life care are of critical importance for the quality of end-of-life care and the professional roles they will undertake in this regard in the future. This study aimed to examine nursing students’ perceptions of good death, their attitudes towards the principles of dignified death, euthanasia, and the relationship between them. Methods: The sample of this cross-sectional descriptive-correlational study consisted of 259 nursing students in the 2nd, 3rd, and 4th year at two state universities in Türkiye during the 2023–2024 academic year. Data were collected with the “Personal Information Form,” “Good Death Scale,” “Assessment Scale of Attitudes toward the Principles of Dying with Dignity (ASAPDD)” and “Euthanasia Perception Scale.” Results: Nursing students’ ASAPDD (49.21 ± 6.42) and Good Death Scale (57.18 ± 2.65) mean scores were above average. Regarding euthanasia, the positive (52.89 ± 16.87) and cultural (11.50 ± 2.90) sub-dimensions were above average, the negative sub-dimension was moderate (28.44 ± 8.47), and the penal (11.64 ± 5.17) and opportunistic (7.05 ± 2.84) sub-dimensions were below average. Conclusions: Nursing students generally approached dignified and good death positively and held supportive views on euthanasia, particularly in its positive and cultural dimensions. Nursing students did not support punitive approaches toward euthanasia and the idea of deriving personal profit from its implementation. As students’ attitudes toward the principles of dignified death increased, their perceptions of a good death and positive and cultural attitudes toward euthanasia also increased. As students’ perceptions of a good death increased, cultural attitudes also increased. These results highlight the importance of incorporating ethics and end-of-life care education into the nursing curriculum. Clinical trial number: Not applicable