Texas Journal of Medical Science
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Possibilities Of Computed Tomography In The Diagnosis Of Central Lumbar Spinal Canal Stenosis
The possibility of visualizing spinal pathology allows us to consider CT as the main and most accessible diagnostic method for vertebral and discogenic lesions, which can be used to accurately identify pathological changes that cause central lumbar spinal canal stenosis. CT with SCT and MSCT was perceived by many scientists as the biggest step forward in radiation diagnostics since the discovery of X-ray
Nutritional Principles And Dietary Management In Patients With Liver Disease
Liver diseases are characterized by complex metabolic, hormonal, and inflammatory alterations that profoundly affect nutritional status, body composition, and clinical outcomes. Malnutrition and sarcopenia are highly prevalent in chronic liver disease and independently predict morbidity, mortality, and reduced quality of life. This review synthesizes contemporary evidence on nutritional disturbances and dietary interventions in liver disease. A structured narrative analysis of international and regional literature examined energy and protein metabolism, micronutrient deficiencies, muscle wasting, and disease-specific dietary strategies. The findings indicate that adequate energy and protein intake, appropriate meal timing, and individualized nutritional support reduce catabolism, preserve muscle mass, and improve functional status. Targeted correction of vitamin D and zinc deficiency may further support metabolic and immune functio
Ishemic Stroke
Ischemic stroke is an acute neurological syndrome caused by the sudden interruption of cerebral blood flow due to thrombus formation or atherosclerotic occlusion of intracranial vessels. This article reviews the pathogenesis, key clinical manifestations, diagnostic modalities, and stepwise treatment protocols for ischemic stroke. Timely recognition and appropriate management significantly reduce mortality and long‐ term disability
Evaluation Of The Acetylation Process And Blood Lipid Profile In Patients With Chronic Periodontitis Associated With Hepatitis C
The purpose of this study was to investigate the relationships between allelic variants of acetylation and the blood lipid profile in patients with chronic periodontitis associated with hepatitis C. Biochemical studies were conducted on 42 individuals aged 18–45 years (24 men and 18 women) diagnosed with chronic periodontitis associated with chronic hepatitis C. The acetylation phenotype in saliva and the blood lipid spectrum were studied. A higher prevalence of the disease was noted among patients with a slow acetylation phenotype in saliva, averaging 17% in the primary group. Patients with a slow acetylation phenotype demonstrated elevated triglyceride levels, which were accompanied by lower concentrations of cholesterol, high-density lipoproteins (HDL), and low-density lipoproteins (LDL) in the blood
Clinical Pharmacological Approach To The Treatment Of Infectious Diseases With Antiviral Drugs
The clinical efficacy and safety of riamilovir were assessed based on the results of a study of 150 patients in three compared groups, 50 patients in each. Patients received etiotropic antiviral therapy with riamilovir, 1 capsule (250 mg) 3 times a day for 5 days in the first group, in the second group patients received riamilovir in the “off label” regimen, 1 capsule (250 mg) 5 times a day for 5 days, and the third group consisted of 50 patients who received only pathogenetic treatment. The etiotropic antiviral drug riamilovir demonstrated clinical efficacy when used in both treatment regimens in patients with ARVI and a good safety profil
Structure, Function, and Diseases of the Heart
"Structure of the Heart" Topic This topic provides brief information about the anatomical and morphological structure of the heart, its chambers – the right and left atria and ventricles, the valve system, the role of the heart in blood circulation, and the layers of the heart wall (endocardium, myocardium, epicardium). It also covers the internal and external structures of the heart, the flow of blood through the heart, and the working principle of cardiac muscles. This topic is important for understanding the basics of heart function
Current Challenges In Modern Preventive Medicine
This article provides a comprehensive overview of the most pressing issues in modern preventive medicine. It discusses the challenges posed by vaccine hesitancy, the increasing prevalence of chronic diseases, lifestyle-related health problems, and the unequal distribution of healthcare resources. The article also delves into the complexities of health promotion in a rapidly changing world, including the impacts of urbanization, globalization, and technological advancements on disease prevention. In conclusion, the article highlights the need for an integrated approach, involving governments, healthcare professionals, and the public to overcome these challenges effectively
The Role Of Artificial Intelligence In Biomedicine: Personalized Medicine And Diagnostic Capabilities In The Context Of Uzbekistan
This article explores the capabilities of artificial intelligence (AI) technologies in the field of biomedicine in the context of Uzbekistan in the field of personalized medicine and diagnostics. The article analyzes the importance in early detection of diseases, optimization of treatment and formulation of approaches that meet the individual needs of patients. The benefits of implementation in the healthcare system of Uzbekistan, existing barriers and future prospects will be discussed. The study aims to adapt global experience to local conditions with an emphasis on infrastructure, training and international cooperation. The article presents practical proposals for the use of AI in the modernization of the healthcare system of Uzbekista
Morpho-Functional Changes Of The Kidneys In Hypoparathyroidism: A Comprehensive Review
Hypoparathyroidism (HPT) is a rare endocrine disorder characterized by chronic parathyroid hormone (PTH) deficiency, resulting in persistent hypocalcemia, hyperphosphatemia, and reduced calcitriol synthesis. These biochemical abnormalities have a profound impact on renal morphology and function. Numerous studies indicate that long-standing HPT predisposes patients to nephrocalcinosis, nephrolithiasis, tubular injury, interstitial fibrosis, and a progressive decline in glomerular filtration rate. Despite increasing recognition of renal involvement, comprehensive evaluation of morpho-functional kidney changes in HPT remains limite
Analysis Of The Effectiveness Of Total Neoadjuvant Therapy In The Treatment Of Patients With Rectal Cancer
One of the major limitations of the traditional treatment sequence is that a substantial proportion of patients are unable to complete planned adjuvant chemotherapy. Postoperative complications, prolonged recovery, stoma-related issues, and decreased performance status frequently lead to dose reductions, treatment delays, or complete omission of systemic therapy