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The Effect of Postexposure Sleep Deprivation on Anxiety-Related Behaviours and Hippocampal Neuropathological Changes in a Rat Model of Posttraumatic Stress Disorder
Sleep problems are a hallmark of posttraumatic stress disorder (PTSD). Although the critical role of sleep for memory consolidation is well known, there is no consensus on the effect of sleep interruption or increased sleep duration immediately after a traumatic experience on the development of PTSD. In addition, the effect of the loss of specific sleep stages postexposure on the development of PTSD is not fully elucidated. Using the single prolonged stress (SPS) procedure, we aimed to determine the effect of postexposure REM sleep deprivation (REMSD) or total sleep deprivation (TSD) on memory function, anxiety-related behaviours and related biochemical parameters. Fear and anxiety-like behaviour, hippocampal BDNF and acetylcholinesterase (AChE) levels in animals exposed to SPS alone or to the combination of SPS + REMSD or SPS + TSD were tested against a group of unexposed control animals. In our study, we found that SPS rats had impaired memory formation and performed poorly on anxiety-related behaviours. The effects of REMSD or TSD on anxiety-related behaviours after SPS were similar and did not result in a significant improvement. Furthermore, posttraumatic TSD further reduced the SPS-induced decrease in hippocampal BDNF expression, while it also increased hippocampal AChE levels to a similar extent. These findings underscore the importance of sleep as a focus for ongoing research into the pathogenesis of PTSD, and the fact that eliminating specific REM or total sleep immediately after trauma exposure has limited effects on the development of PTSD
Publication Dynamics and Collaboration Networks in Prenatal Care Research: A Scopus-Based Bibliometric Analysis (2020–2024)
Weld properties of plasma arc joined austenitic stainless steels
Stainless steel 304 is the commonly utilized grade within the 300 series in various industries. Welding is a prevalent technique for producing stainless steel structures. In this study, 5 mm thick AISI 304 sheets were joined by plasma welding. The joint interface was detected using energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), elemental mapping, X-ray diffraction (XRD), and microhardness. The mechanical properties of the bonded samples were evaluated by tensile testing. The fracture morphologies of the tensile test samples were examined. In single-pass plasma welding, perfect welds with full penetration were achieved. Both ultimate tensile strength (UTS) and elongation percentage increased with the rise in welding current
Effect of substrate temperature on the photocatalytic degradation efficiency of methylene blue using TiO₂ thin films
Bioaccumulation of Nickel Ions by Rhizopus delemar
The current research investigated the bioaccumulation of Ni(II) ions by Rhizopus delemar in molasses-containing fluids in a batch reactor. Due to the low pH requirements that R. delemar requires, it may grow in wastewater, which has an acidic pH. In the absence of Ni(II) ions, the influence of pH and molasses concentration on the growth rate and concentration of R. delemar were examined. The highest level of microbial growth occurred at a pH of 4.0. Up to 20 g/L of sucrose content increased the maximum R. delemar concentration and the specific growth rate. While the substrate content in each growing medium including molasses was kept constant at 10 g/L, initial concentrations of metal ions were changed between 50 and 250 mg/L to evaluate the bioaccumulation of Ni(II) ions. It was discovered that when metal ions existed, the rate of microorganism growth slowed down as the metal ion concentration increased. The maximum growth rates were discovered to be 0.257 h-1 in the presence of 50 mg/L Ni(II). When media containing 50 mg/L Ni(II) ions, the efficiency of Ni(II) bioaccumulation was found to be 51.8%
High-Resolution Documentation of Historical Structures Using Terrestrial Laser Scanning: Ürgüp, Türkiye
The collective memory of societies is defined as a cultural heritage. However, this heritage is threatened by bothnatural and human-made factors and requires effective conservation and management documentation.Traditional methods are often time-consuming and require faster, more accurate, and cost-effectivetechnologies. This study documents a historic masonry house in Ürgüp, Nevşehir, Turkey, using Terrestrial LaserScanning (TLS). In this study, nine external and 25 internal scanning positions were used, and the data wereprocessed into 3D models, orthophotos, and other output sections. According to the results, the measurementdifferences ranged from 1 to 3 cm, with an average of 2.30 cm. This result confirms the reliability of the methodand demonstrates that terrestrial LiDAR scanning is invaluable for cultural heritage conservation, despite its highcost and complex data processing. Supporting the method with precise architectural drawings sets a highstandard for the documentation of historic stone structures and provides a solid foundation for futurerestoration studies.Keywords: 3D building model, historical building documentation, LiDAR, terrestrial laser scanning</p