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    Gıdalarda Yenilikçi Muhafaza Teknikleri

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    Cinsel Sağlık ve Üreme Sağlığı

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    Response of inflammatory cytokine levels in calves with LPS-induced endotoxemia

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    The most common form of toxemia observed in large animals is endotoxemia. Endotoxemia is caused by the presence of lipopolysaccharide cell wall components of gram-negative bacteria in the blood and characterized clinically by abnormalities of many body systems. This study aimed to determine changes in serum inflammatory cytokine levels in calves with LPS-induced endotoxemia. Ten healthy Holstein breed calves were used in the study. To create experimental endotoxemia, LPS at 0.1 µg/kg dose was given intravenously to the calves from the vena jugularis as an infusion within 30 min. Blood samples to evaluate cytokines, biochemical, blood gases, and hematological parameters were collected before LPS infusion (0. hour) and at 1, 2, 3, 4, 6, 12, 24, and 36 h following LPS infusion. In the first 4 h following the LPS infusion, calves’ body temperature, heart and respiratory rate, and capillary refill time increased, while a decrease was observed in the following hours. Significant changes were detected in blood pH, WBC, and glucose levels after LPS administration. Serum TNF-α, IL-6, IL1-β, IL-10, and IFN-γ levels were low before the LPS infusion in the calves, while increased within the first 4 h following the LPS infusion, however, statistical significance was observed in TNF-α, IL-6, and IFN-γ. Cytokine levels decreased back to baseline levels after the fourth hour. As a result, it was found that 0.1 µg/kg dose of LPS administrated as infusion caused changes in clinical, hematological, blood gases, biochemical parameters, and significant increases in the levels of circulating cytokines. The results of this study showed that the changes observed in the organism during natural endotoxemia can also be revealed experimentally by administering LPS intravenously

    Traces of Situationist Theory oi Howard Brenton’s The Arrest Of Ai Weiwei

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    ÖzetHoward Brenton’un&nbsp;The Arrest of Ai Weiwei&nbsp;oyunu, Situationist Enternasyonal’in “Gösteri Toplumu” eleştirisinden hareketle, çağdaş toplumun görsel ve tüketici bir yapıya dönüştüğünü ve bireyleri giderek daha fazla kontrol altına aldığını ortaya koymaktadır. Oyun, Ai Weiwei’yi, sanatını bir direniş aracı olarak kullanan bir figür olarak sunar. Ai Weiwei, mevcut kültürel formları yeniden amaçlandırarak (détournement yaparak) ve onları beklenmedik bağlamlarda kullanarak, gösteri toplumunun dayandığı mekanizmaları altüst eder. Günlük nesnelerden karmaşık enstalasyonlara kadar uzanan sanat eserleriyle, Ai Weiwei izleyicileri çevrelerini derinlemesine sorgulamaya ve mevcut düzeni sorgulamaya teşvik eder. Durumcuların (Situationistlerin) kentsel alanları devrimci eylem alanları olarak görmesiyle paralel olarak, oyun, Ai Weiwei’nin şehri bir sanat alanı olarak kullanarak kamu mekanlarını eleştirel birer alana dönüştürdüğünü gösterir. Brenton, bu oyununda, Situationist teorileri kullanarak günümüzün yaşamsal sorunlarına dikkat çeken ve sanatsal ve toplumsal dönüşüm için yeni bir vizyon sunan güçlü bir tiyatro deneyimi sunar.Anahtar Kelimeler: Situationist Enternasyonal, Guy Debord, Howard Brenton, Ai Weiwei, Détournement.&nbsp;ABSTRACT Howard Brenton’s The Arrest of Ai Weiwei engages with the Situationist International’s critique of the “Society of the Spectacle,” exploring how contemporary society is increasingly mediated and controlled by images and consumerism. The play presents Ai Weiwei as a figurehead of resistance, utilizing his artistic practice to subvert the spectacle through playful détournement – the reappropriation and subversion of existing cultural forms. Ai Weiwei’s artistic interventions, from his reconfigurations of everyday objects to his provocative public art installations, are presented as acts of resistance that challenge the established order and encourage viewers to question the meaning and function of their surroundings. The play further emphasizes the Situationist interest in the urban landscape as a terrain for revolutionary action, portraying how Ai Weiwei uses the city as a canvas for his art, transforming public spaces into sites of critical intervention. By analyzing these key elements – the critique of the spectacle, the embrace of détournement, and the exploration of the urban as a site of resistance – this article demonstrates how Brenton utilizes Situationist theory to construct a powerful and provocative theatrical work that resonates with contemporary anxieties and offers a vision of artistic and social transformation. Keywords: Situationist International, Guy Debord, Howard Brenton, Ai Weiwei, Détournement&nbsp;</p

    Kalplere Dokunan Merhamet Çağrısı

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