Seminars in Medical Writing and Education
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Research Progress of Artificial Intelligence Deep Learning Technology in the Field of Network Pharmacology
Full text linkRheumatoid arthritis (RA), a complex autoimmune disease, results in chronic inflammation and progressive joint degradation. While resveratrol has shown considerable therapeutic potential due to its anti-inflammatory properties, the precise molecular mechanisms underlying its effects in RA remain unknown. To improve the identification and validation of resveratrol\u27s therapeutic targets in RA, a deep learning (DL)-enhanced approach is proposed, building on current research that combines bioinformatics, network pharmacology (NP), and artificial intelligence (AI). The method integrates RA patients\u27 transcriptome data with PharmMapper-based medication target identification and DL powered protein structure modeling using AlphaFold. To increase prediction accuracy, a Deep Neural Network (DNN) model is used, trained on known drug-target interactions and gene expression data. This enables more precise identification of potential therapeutic genes (PT-genes), such as PIK3CA, AKT1, MAPK1, JUN, PTGS2, CXCL8, and CCL2, which are associated with RA-related pathways such as chemokine signaling, PI3K-Akt, and MAPK. These targets are verified through the analysis of protein interactions, the use of AutoDock Vina to run simulations to determine how well they fit with particular molecules, the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) analysis to investigate gene functions, and the use of Cytoscape\u27s Molecular Complex Detection (MCODE) tool to identify significant genes that express themselves differently. When compared to existing techniques, the suggested model has higher sensitivity and specificity in predicting important therapeutic genes. The framework finds new hub targets with high resveratrol binding affinity, implicating them in RA pathways. This hybrid computational process improves the accuracy and scalability of therapeutic mechanism discovery and helps the development of tailored RA therapies
Neuroeducation in initial basic education: Strategies and benefits for early learning
Full text linkIntroduction: The teaching-learning process in children, an important part of their personal development, cannot be conceived without considering its complexity, making it a key issue in the field of neuroeducation. Objective: The purpose of this article was to describe the benefits of neuroeducation for stimulating early learning. Methods: A systematic review was conducted, examining 20 digital documents from 2017 to 2024, indexed in academic repositories: Dialnet, SciELO, and Redalyc. The methodology used was PRISMA with a qualitative approach. The inclusion criteria included articles published in the last decade with a maximum length of 6500 words. Doctoral theses, systematic review and those documents not available to be downloaded were excluded.Results: It is described that although neuroeducation can adapt to any age, strategies and teachings that seek to facilitate natural learning should be prioritized. However, this requires educators to have a greater understanding of children\u27s brains and, above all, a commitment to their own professional development to gain competence in applying new proposals. Conclusions: In the educational role of teachers in basic education, the application of neuroeducational strategies is essential to enhance early learning. Educators need to understand the characteristics of child development and use innovative, easily accessible resources in the classroom. Professional development in neuroscience improves attention, concentration, and stimulates cognitive and socio-emotional skills, as well as intrinsic motivation in children
Ethnoscience Materials to Build Scientific Literacy
Full text linkIntroduction: Students\u27 scientific literacy skills were often overlooked due to teaching materials that failed to incorporate local cultural context. This study aimed to identify teaching materials currently employed in elementary science education fourth-grade students in \u27Sekolah Penggerak\u27 programs in Sukoharjo Regency, Central Java, Indonesia, and assess students\u27 scientific literacy within this context.Methods: The study employed a descriptive qualitative approach with participants including fourth-grade educators and students from elementary schools in the "Sekolah Penggerak" program in a Javanese province, Indonesia. Two schools participated: State Elementary School 02 Duwet and State Elementary School 04 Ngadirejo. Data were obtained through surveys and interviews using purposive sampling techniques. Questionnaires were distributed to students, while interview data were gathered from teachers.Results: The majority of teaching resources were government- or publisher-provided books that lacked cultural relevance and were not designed to improve scientific literacy. Teachers had not created instructional materials that were literacy-focused or culturally appropriate. Scientific literacy levels among students were found to be very low.Conclusions: The findings demonstrated the urgent need to develop ethnoscience-based instructional materials that integrated local culture, technology, and inquiry-based learning methodologies. Such resources would strengthen students\u27 comprehension, increase their scientific literacy, and provide tangible learning experiences that connected scientific concepts to their cultural context
Introducing Health Literacy at the Primary School Level: A Pedagogical Model for Early Scientific and Medical Education
Full text linkHealth literacy now stands as a cornerstone for lifelong well-being, yet most educational initiatives focus on adolescents or adults, neglecting the formative primary school years when foundational attitudes and habits form. This study addresses that gap by proposing a pedagogical model for introducing health literacy to children aged 6–12, with the goal of developing basic scientific understanding, health awareness, and responsible decision-making from an early age. The research draws on interdisciplinary perspectives from health science education, child psychology, and communication theory, underscoring the urgency of early intervention to reduce long-term health inequalities.
A mixed qualitative–quantitative approach was used, combining content analysis of 45 peer-reviewed publications and policy reports with thematic synthesis of case studies and pilot programs from diverse educational contexts. Data analysis identified key competencies, effective pedagogical strategies, and barriers to implementation.
The results highlight three main lines of work: (1) integration of age-appropriate health topics—hygiene, nutrition, body awareness, emotional well-being, and responsible use of healthcare services—into existing curricula; (2) adoption of innovative teaching methods such as storytelling, interactive games, role-play, and visual learning tools to make complex health concepts accessible; and (3) promotion of collaboration between educators, healthcare professionals, and families to reinforce learning in both school and home environments.
The findings show that structured, engaging, and contextually adapted health literacy education at the primary level can lay the foundation for informed, health-conscious future citizens. The conclusions of the paper discuss implications for policy, curriculum design, and sustainable cross-sector partnerships
Positive Discipline and Educational Climate: A Systematic Review from an Andragogical Approach
Full text linkIntroduction: Positive discipline has positioned itself as an educational alternative within educational processes, especially in the field of higher education, where andragogical principles demand an approach focused on autonomy and mutual respect. Its application seeks to transform the educational climate, promoting more empathetic and collaborative relationships between teachers and students.Objective: To analyze the impact of positive discipline and the educational climate in higher education contexts from an andragogical perspective.Method: A qualitative approach was used through a literature review of scientific articles. The search was conducted in specialized databases such as Scopus, Springer, Scielo, Taylor & Francis, ProQuest, and Redalyc, using Boolean operators “AND” and “OR” to optimize the identification of relevant documents.Results: The studies reviewed show that positive discipline, far from being an isolated behavioral technique, represents a comprehensive educational approach that promotes empathy, self-regulation, and mutual respect. In higher education, its implementation strengthens key competencies in adult students, such as autonomy, intrinsic motivation, and the ability to make responsible decisions. Likewise, it was identified that external social and cultural factors influence student behavior and that, if not understood from a holistic perspective, they can lead to authoritarian and ineffective educational responses.Conclusions: The impact of positive discipline and the educational climate in higher education depends on the institutional capacity to articulate theory and practice under the principles of andragogy. Only through a coherent and contextualized approach can educational environments be created that promote coexistence, autonomous learning, and the comprehensive development of adult students
Harnessing Metaverse-Driven Project-Based Learning in TVET: Elevating Higher-Order Thinking Skills for the Future Workforce
Full text linkThe fast evolution of the immersive digital technologies has changed education and brought about new possibilities of interactive and experiential learning. One of those innovations is the Metaverse, which can be used to provide an experience of real-life virtual environments that can improve engagement and collaboration, although its pedagogical applications in vocational education are less explored. Addressing the demand of graduates with the advanced skills of analytical, creative and problem-solving, this research paper explores how the Metaverse-based Project-Based Learning (PjBL) can enhance Higher-Order Thinking Skills (HOTS) in students of Technical and Vocational Education and Training (TVET). Quasi experimental design was used with pre-test and post-test control groups to compare the results of Metaverse-integrated and traditional PjBL. The learning gains in the students were measured by collecting data using a HOTS assessment test and analyzing them using both descriptive and inferential statistical techniques. Findings show that the students in the Metaverse group made significantly better improvement in HOTS especially in analysing, evaluating and creating dimensions than the students in the control group. These results prove that PjBL with the implementation of the Metaverse contributes to better intellectual results among students and greater involvement in the educational process.Regardless of the difficulties concerning the infrastructure and instructor preparation, the research finds that Metaverse-powered PjBL is a powerful instructional framework to develop 21 st -century skills in the TVET education
From Education to Transformation: Uncovering the Mechanisms of Strengthening Environmental Health Literacy through the Implementation of the Adiwiyata Program De la Educación a la Transformación: Revelando los Mecanismos de Fortalecimiento de la Alfabetización en Salud Ambiental a través de la Implementación del Programa Adiwiyata
No full textIntroducción:
Los estudios sobre alfabetización en salud ambiental han avanzado significativamente; sin embargo, su implementación en las escuelas sigue siendo meramente ceremonial, no pedagógica, lo que limita su impacto en la transformación del comportamiento en el entorno escolar. Este estudio busca identificar las iniciativas para fortalecer la alfabetización en salud ambiental dentro del Programa Adiwiyata en diversos niveles educativos de Sumatra Occidental, como parte de la transformación de la salud ambiental en las escuelas.
Métodos:
Este estudio empleó un diseño cualitativo. Los informantes incluyeron directores de escuela, docentes y estudiantes seleccionados mediante muestreo intencional. Se utilizó un Procedimiento Manual de Análisis de Datos (MDAP) para identificar temas y patrones relacionados con el desarrollo de la alfabetización en salud ambiental.
Resultados:
Los resultados de la investigación indican que el Programa Adiwiyata fomenta el aprendizaje contextual y aumenta la participación de la comunidad escolar en comportamientos saludables y respetuosos con el medio ambiente. Por ejemplo, las escuelas desarrollan materiales educativos que fomentan hábitos respetuosos con el medio ambiente entre los estudiantes, integrando temas ambientales en todas las asignaturas. El ODS 3, La alfabetización en salud ambiental se mejora mediante diversas actividades prácticas, como la gestión de residuos, iniciativas de escuelas verdes y actividades de servicio comunitario. La eficacia del programa se basa principalmente en el liderazgo visionario de la escuela y sus prácticas docentes innovadoras.
Conclusiones:
El éxito del Programa Adiwiyata depende en gran medida de la capacidad del profesorado para integrar los principios de la salud ambiental en prácticas pedagógicas sostenibles
Artificial Intelligence and Medicine: Where is scientific and technical development taking us?
Full text linkIntroduction: Clinical reasoning is the fundamental tool in the work of the physician, and has benefited from current techno-scientific advances, which at the same time try to replace the work of the health professional. In this way, the doctor-patient relationship, the essential link in the procedures of the clinical method, deteriorates. Artificial intelligence and other innovations have revolutionized health institutions, the way of approaching medical care, clinical reasoning and the teaching-learning process of medicine. This research aims to provide a comprehensive understanding of medical reasoning inextricably linked to the techno-scientific development of society and especially to Artificial Intelligence. Results: Using Artificial Intelligence as a clinical reasoning tool facilitates the treatment of patients without replacing the role of the physician. It also explores its impact on medical decision-making and the ethical aspects of data storage. Conclusions: A comprehensive understanding of clinical reasoning inextricably linked to human social development is necessar
Teachers’ Self-Efficacy belifs in China: A Literature Review (2015-2025)
Full text linkThis study reviews literature on teachers’ self-efficacy beliefs in China from 2015 to 2025, aiming to identify key trends, influencing factors, and research gaps. Rooted in Bandura’s social cognitive theory, it examines how instructional leadership, professional development, classroom management, and student outcomes shape teachers’ self-efficacy. Using a systematic literature review, relevant studies were analyzed based on theoretical foundations, methodologies, and findings. Results indicate that educational reforms, regional disparities, and professional expectations significantly impact self-efficacy, with instructional leadership and training playing positive roles, while rural areas face persistent challenges. The discussion highlights policy and practical implications, emphasizing the need for targeted interventions and further research on digital education and cultural influences. This review contributes to understanding self-efficacy in China’s educational context and provides insights for policymakers, educators, and researchers. Its originality lies in synthesizing recent studies to offer a comprehensive perspective on evolving trends and challenges in teacher self-efficacy
External treatment methods of Traditional Chinese Medicine for Insomnia in Patients with hypertension: Network Meta-analysis
Full text linkInsomnia is a mutual comorbidity in hypertensive patients, complicating the management of both conditions. Traditional Chinese medicine (TCM) offers various external treatments, including acupuncture, acupressure, and cupping, which have demonstrated the potential to improve sleep quality and regulate blood pressure. The goal of the network meta-analysis is to compare the efficacy of various external TCM interventions in treating insomnia in patients with hypertension. Comprehensive research for RCTs published between January 2019 and December 2025 is shown in a number of databases, such as PubMed, the Cochrane Library, Web of Science (WoS), and others. The analysis focused on trials evaluating the impact of external TCM treatments on insomnia and blood pressure in hypertensive patients. Utilizing a network meta-analysis methodology, the relative efficacy of acupressure, acupuncture, and cupping in alleviating insomnia symptoms and reducing blood pressure is compared. The Cochrane Risk of Bias tool is used to evaluate the quality of analyses. The analysis included 35 RCTs with a total of 3,200 patients. According to the data, acupuncture is the greatest treatment for treating sleepiness and decreasing both systolic and diastolic blood pressure levels. Acupressure and cupping were also effective but to a lesser extent than acupuncture. The meta-analysis suggests that external TCM treatments, especially acupuncture, provide significant benefits for managing insomnia and improving blood pressure in hypertensive patients. However, further research is necessary to refine treatment protocols and optimize outcomes