Seminars in Medical Writing and Education
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The Role of Melatonin in Insomnia and Neurodegenerative Conditions: A Critical Study
Full text linkThe subsequent leading cause of mortality, neurodegenerative diseases (ND), gradually reduces the capacity of the central or peripheral nervous system to function properly and think coherently. In contemporary culture, the primary goal of public health is ND prevention. Numerous physiological functions in the brain are regulated by the hormone Melatonin (MLT), It was generated in the Pineal Gland (PG). Circadian rhythms (CR), biomolecular oxidation, eliminating free radicals, and preventing neuroinflammation are some of these mechanisms. MLT has been proven to have a multitude of neuroprotective effects through altering signaling pathways and pathophysiological processes. Neurological disorders may cause lower MLT levels. MLT regulates itself, interacts with molecules, and affects biological processes in ND. We also discuss the therapeutic use of MLT in the management of neurodegenerative illnesses. This knowledge might lead to the development of cutting-edge therapeutic approaches for the treatment of different ND and further our understanding of how MLT controls the brain\u27s Circadian Rhythm (CR)
Crisis and transformation of the medical residency system in Argentina
Full text linkIntroduction: For decades, the medical residency system in Argentina was the main and most highly valued route for training specialists. Regulated by the Ministry of Health, these programs offered a comprehensive model of theoretical and practical training in hospital settings. However, since 2021 there has been a sustained drop in the number of applicants, which shows a change in students\u27 perception of this traditional format.Development: The admissions process included a national exam, academic records and interviews. The training combined clinical rotations, professional supervision, constant evaluation and long on-call hours. Despite this, future doctors began to question the usefulness of the system in the face of current working conditions. Data collected between 2014 and 2024 showed a downward trend in enrolments from 2021 onwards, with a slight upturn in 2024. At the same time, the participation of foreign graduates remained high, especially from Latin American countries, who occupied more than 30% of the places offered.Conclusions: It was concluded that medical residency, although still in force, lost its appeal for many 6th year students. Precariousness, low pay and the search for a better quality of life explained this phenomenon. Alternatives such as private practice, working abroad or training outside the system began to gain ground. Faced with this transformation, it became urgent to modernize the system and adapt it to new professional and human demands
Educational innovation for entrepreneurship in the university systemAxis model applied in CUAltos
Full text linkAcademic entrepreneurship has established itself as a strategic pillar in higher education by promoting competencies focused on innovation, sustainability, and productive transformation. This article presents the experience of the Centro Universitario de los Altos in implementing a multi-axis model that combines different institutional components with the aim of strengthening the entrepreneurial ecosystem in the educational environment. The multi-axis model promotes interaction between the university, industry, and government and integrates socio-ecological, cultural, and digital factors that enable the development of a knowledge-based economy. Through this approach, students acquire essential entrepreneurial skills, digital competencies, and interdisciplinary skills necessary to succeed in a rapidly evolving market. The results underscore the effectiveness of this model in bridging the gap between academic knowledge and industry needs, ultimately fostering innovation and sustainable development
From Novice to Expert: A Novel Framework for Understanding Nursing Educator Competency in the Digital Age.
Full text linkIntroduction: Educator competency is vital for teaching quality and student success, especially amid evolving educational technologies and paradigms. Traditional models often overlook the interplay of individual, institutional, and technological factors.
Objective: This study aimed to identify predictors of educator competency and examine the influence of teaching experience, institutional context, and technology integration on teaching effectiveness in higher education.
Methods: A cross-sectional survey was conducted with 626 educators from universities, health science colleges, and polytechnics. A validated questionnaire assessed five competency domains: Teaching Methods, Digital Literacy, Content Knowledge, Assessment Skills, and Communication. Data were analyzed using t-tests, ANOVA, Bayesian estimation, and effect size measures.
Results: Teaching experience significantly predicted competency progression from novice to expert levels (d = 0.45), with Communication emerging as the strongest domain. Digital literacy scored lowest, particularly in virtual lab implementation (mean = 58.5), indicating a critical gap. Institutional disparities revealed resource limitations impacting competency development. Hybrid learning was the most effectively adopted technology (mean = 88.2).
Conclusions: The study highlights the importance of experience, institutional support, and strategic technology use in shaping educator competency. The ACDE-DA framework offers a holistic model for guiding policy and professional development. Targeted interventions in digital literacy, equitable resource distribution, and ongoing training are essential. Future research should employ longitudinal designs to validate findings across diverse educational contexts
Integrating Values Education in Physical Education Learning: A Holistic Approach to Enhancing Student Well-Being
Full text linkThis research is urgent because physical education has the potential to instill character values through a holistic approach, yet its practice remains predominantly technical. Value integration is crucial for student well-being and character. This study aims to explore how Physical Education teachers integrate values education into learning through a holistic approach at various levels of education (elementary, junior high, and senior high) in West Sumatera. Using a qualitative approach with a collective case study design, this study involved 30 Physical Education teachers selected through area sampling techniques. Data were collected through semi-structured interviews, limited observations, and field notes, then analyzed thematically. The results showed that teachers consistently integrated moral and social values such as honesty, discipline, responsibility, cooperation, and sportsmanship into physical education learning activities through interactive methods, game modifications, role models, reflection, and community involvement. These values were understood by students not only as rules in games, but also as life principles relevant to their social lives. The holistic approach has been proven to contribute positively to student well-being through strengthening physical skills, developing character, improving mental health, and creating a supportive learning environment. However, teachers face various challenges such as differences in student character, lack of parental support, limited time and resources, and communication barriers that require special strategies. This study confirms that value education through Physical Education can be an effective instrument in shaping character and improving student welfare, as long as it is carried out contextually, reflectively, and involves various parties collaboratively
Exploring the Impact of Digital Promotion and Online Reviews on the Growth of Medical Tourism: A PLS-SEM Study
Full text linkIntroduction: medical tourism is rapidly expanding, and digital channels such as promotion and online reviews are increasingly shaping patient decisions.Objective: this study examines the impact of digital promotion and online reviews on medical tourists’ perceived trust, perceived value, and behavioral intentions.Method: data were collected from 218 respondents with prior cross-border medical experiences through online platforms and medical tourism agencies. Partial Least Squares Structural Equation Modeling (PLS-SEM) and fuzzy-set Qualitative Comparative Analysis (fsQCA) were used to test relationships and identify pathways influencing behavioral intentions.Results: digital promotion and online reviews significantly increased perceived trust and perceived value. However, only perceived value directly and strongly influenced behavioral intentions. Perceived value also mediated the effect of online reviews on behavioral intentions. FsQCA results confirmed perceived value as a necessary condition and revealed multiple sufficient pathways combining promotion, reviews, and value perceptions to strengthen behavioral intentions.Conclusions: perceived value plays a central role in medical tourists’ decision-making, suggesting that enhancing value perceptions through effective digital promotion and credible online reviews is key to strengthening competitiveness in the medical tourism industry
Integrating Generative AI into Bioenergetics Modules: A PAIRR-Based Approach for Senior High School Biology
Full text linkIntroduction: artificial intelligence (AI) offered transformative potential for enhancing learning and academic support, but its systematic integration into science-specific modules aligned with DepEd guidelines had not been fully explored. Bioenergetics, a complex topic in senior high school biology, remained a persistent challenge for learners.Methods: the study developed a Generative AI–integrated bioenergetics module using the Peer and AI Review + Reflection (PAIRR) approach. A mixed-method design combined quantitative analysis with qualitative support. Module validation assessed Student Involvement Index, feedback-based readability, and Communication Index. A limited trial was conducted with 64 11th grade learners. Achievement scores before and after module use were analyzed using the Wilcoxon Signed Rank test, and post-implementation interviews captured learner perceptions.Results: the module achieved acceptable validation scores for Student Involvement Index (1,08), feedback-based readability, and Communication Index (0,003). Learners’ achievement scores improved significantly after using the module (p < 0,05). Students reported that AI provided personalized support, clarified complex bioenergetics concepts, and enhanced engagement. Challenges included intermittent internet connectivity, uneven group participation, time constraints, and initial difficulty using ChatGPT.Conclusions: the Generative AI–integrated module effectively enhanced learners’ understanding of bioenergetics, demonstrating AI’s potential as a collaborative peer in science education. Further research should evaluate scalability, long-term impact, and adaptability across other science topics
Analysis Of Structural Equation Modeling (Sem) The Most Significant Risk Factor For Hypertension In The Islands Region
Full text linkIntroduction: Hypertension is a non-communicable disease which is a major global public health challenge, especially in areas with limited access to health such as island areas. Island residents also have the potential to experience hypertension, the more dominant factor in this region is limited access to health facilities. While lifestyle, work and physical activity also play a role, barriers to obtaining health services are the main factors influencing the prevalence of hypertension in the islands. This study aims to analyze the risk factors for hypertension on three islands in Sangkarrang Islands District, Makassar City, namely Barrang Lompo Island, Kodingareng Island, and Barrang Caddi Island.Methods: The method used is approach Structural Equal Modeling (SEM) to identify the risk factors that most influence the incidence of hypertension.Results: The results of the analysis show that physical activity has a very strong and significant influence on hypertension, with the highest path coefficient on Barrang Lompo Island (0.924). Non-compliance in medication consumption is also the dominant factor contributing to the increase in hypertension on all islands, Kodigareng Island has the highest coefficient of 0.972. Knowledge is also an important factor that contributes to the management of hypertension on all islands, with the greatest influence on Barrang Caddi Island (0.858). On the other hand, the National Health Insurance (JKN) factors (0.197 - 0.719), distance to health facilities (0.388 - 0.577), and duration of suffering from hypertension (0.297 - 0.541) show a weaker and not always significant influence on hypertension
Attitude Towards Research in Formative Research Among University Students: An Analysis from the Perspective of Autonomous Investigative Learning
Full text linkIntroduction: research attitudes and autonomous investigative learning are crucial for the development of scientific competencies in higher education. This study explored the relationship between university students’ attitudes toward research and their perspective on autonomous investigative learning within the framework of formative investigation. The aim was to determine the extent to which positive research attitudes contribute to students’ perceived ability to engage in independent research activities.Methods: a quantitative, cross-sectional, correlational design was employed with a sample of 350 university students from various faculties. Data was collected using a validated questionnaire measuring three dimensions of research attitude (affective, cognitive, behavioral) and a scale assessing the autonomous investigative learning perspective. Descriptive statistics, Spearman’s rho correlation, and linear regression analyses were conducted to examine relationships between variables. Ethical principles, including informed consent, voluntary participation, and confidentiality, were strictly observed.Results: findings indicated moderately favorable attitudes toward research, with higher scores in the affective (M = 3.92) and cognitive (M = 3.85) dimensions, and slightly lower behavioral scores (M = 3.56). A strong, positive correlation was found between attitudes toward research and autonomous investigative learning (ρ = 0.642, p < 0.001). Regression analysis showed that attitudes toward research explained 57.1% of the variance in autonomous learning (R² = 0.571, p < 0.001), with each one-point increase in attitude score predicting a 0.58-point increase in autonomy score. Health sciences students reported higher scores compared to social sciences and engineering students.Conclusions: the results confirm that favorable research attitudes significantly enhance students’ perceived capacity for autonomous investigative learning. To close the gap between positive perception and active engagement, higher education institutions should integrate research experiences early in the curriculum, provide structured mentorship, and ensure equitable access to research opportunities across faculties
Research Progress of Houttuynia cordata on Drug-Resistant Bacteria in Respiratory Tract Infections
Full text linkRespiratory tract infections (RTIs) caused by drug-resistant bacteria represent a major threat to global health, causing increased morbidity, death, and healthcare costs. Houttuynia cordata, a traditionally utilized medicinal plant, has gained attention for its broad-spectrum antibacterial, anti-inflammatory, and immunomodulatory properties. This research examines the advances in the pharmacological research and clinical potential of H. cordata in combating drug-resistant pathogens responsible for RTIs. The research highlighted both the broad-spectrum antibacterial activity of H. cordata extracts and the specific therapeutic efficacy of its active compound, Sodium Houttuyfonate (SH). SH has proven to be effective against several infections, including Haemophilus influenzae, a major drug-resistant bacterium related to pneumonia. In experimental models, SH, an active compound of H. cordata, demonstrated significant therapeutic effects by markedly reducing bacterial burden and mitigating lung tissue inflammation. SH effectively modulated inflammatory and oxidative stress responses, promoting a shift toward immune regulation and tissue protection. This action, distinct from traditional antibiotics, initiated macrophage polarization via the TLR4/TRIF/IRF3 signaling pathway. Furthermore, SH exhibits a dose-dependent antibacterial effect and notable membrane-disrupting capability comparable to known antimicrobial agents. These findings collectively underscore H. cordata\u27s clinical promise as a complementary or alternative therapy against multidrug-resistant respiratory pathogens