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Summary of themes.
No full textA growing body of research demonstrates the potential of mindfulness to reduce employee stress. However, with work increasingly migrating from the physical to the digital workplace, evidence is lacking on how mindfulness might help employees live healthy digital working lives. In addition, employees’ confidence when using the digital workplace is seen as important for productivity but may also play a role in reducing well-being impacts from digital working. Using the Job-Demands Resources model as a theoretical foundation, 142 workers were surveyed regarding their levels of trait mindfulness and digital workplace confidence, along with their experiences of the dark side effects (stress, overload, anxiety, Fear of Missing Out and addiction) and well-being outcomes (burnout and health). 14 workers were also interviewed to provide qualitative insights on these constructs. Results from regression analyses indicated that more digitally confident workers were less likely to experience digital workplace anxiety, while those with higher mindfulness were better protected against all of the dark side of digital working effects. Interview data indicated ways in which digital mindfulness helps protect well-being, as well as how digital workplace confidence enables healthier digital habits.</div
Pie chart distribution of Single nucleotide polymorphisms (SNPs) in <i>SCN9A</i> gene.
No full textPie chart distribution of Single nucleotide polymorphisms (SNPs) in SCN9A gene.</p
Response type, themes, and subthemes for the thematic analysis.
No full textResponse type, themes, and subthemes for the thematic analysis.</p
Recruitment of Arabic schools and participants.
No full textBackgroundMigrant children and adolescents face a significantly increased risk of mental health issues. Focusing on this population’s mental health issues is fundamental and requires more attention to detect and reduce these burdens in adulthood. Nevertheless, life skills intervention can improve mental health. Its effects on Arab migrant adolescents have not been tested. Here, an evaluation protocol of the effect of an online life skills-based intervention for improving depression, anxiety, stress, self-efficacy, and coping skills among Arab adolescents in Malaysia will be examined.Material and methodsThis cluster randomised controlled trial (RCT) will involve 207 Arab students (14–18 years old) from 12 Arabic schools in the Klang Valley. The schools will be assigned randomly to an intervention (online life skills programme) or control group at a 1:1 ratio. The researcher will deliver eight one-hour sessions to the intervention group weekly. The control group will receive the intervention at the evaluation end. Both groups will complete assessments at baseline, and immediately and three months after the intervention. The primary outcome is anxiety, depression, and stress [Depression Anxiety and Stress Scale-21 (DASS-21)]. The secondary outcomes are self-efficacy (General Self-Efficacy Scale) and coping skills (Brief COPE Inventory). Data analysis will involve the Generalised Estimation Equation with a 95% confidence interval. P DiscussionThis will be the first cluster RCT of an online life skills education programme involving Arab adolescent migrants in Malaysia. The results could support programme effectiveness for improving the participants’ mental health problems (depression, anxiety, stress), increasing their self-efficacy, and enhancing their coping skills. The evidence could transform approaches for ameliorating migrant children and adolescents’ mental well-being.Trial registrationThe study is registered with the Clinical Trial Registry (Identifier: NCT05370443).</div
Preliminary search strategy.
No full textBackgroundThe use of combined oral contraceptive (COC) is common among women of reproductive age despite the potential risk of them developing thrombotic events. There is a need to understand how COC affects cardiorespiratory function and markers of immune activation in premenopausal women involved in exercise. This highlights a need for a systematic review to enhance our understanding of how the use of COC affects cardiovascular health in premenopausal women subjected to exercise.MethodThis systematic review protocol was prepared following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) 2015 statement. An extensive search of relevant literature by two independent reviewers will be conducted through the EBSCOhost interface to access databases such as MEDLINE, EMBASE, and CINAHL. Other health sources, including Cochrane CENTRAL, unpublished studies and grey literature, will also be searched. The search will include all studies that report the effect of COC on essential parameters of cardiorespiratory function and markers of immune activation in premenopausal women involved in exercise. All included studies will be appraised using appraisal tools, while appropriate extraction tools will be used for data extraction. Where possible, eligible studies will be pooled for meta-analysis. If statistical pooling is not feasible, our findings will be presented in a narrative format. The certainty of evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluation Assessment (GRADE) tool.Trial registrationPROSPERO registration number:CRD42021265257.</div
Fig 4 -
No full textA. Heatmap of the top ~60 DEGs of HSc vs. HSi, as Log 2 relative hit counts of the comparison between the chickens infected with Eimeria maxima raised under HS (HSi) their uninfected HS control (HSc) at 6 day-post-treatment. B. The top KEGG pathways of HSc vs. HSi, based on the pathway term significance (α≤0.1) of the comparison between the chickens infected with Eimeria maxima raised under HS (HSi) and their uninfected HS control (HSc) at 6 day-post-treatment. The green squares and arrowheads depict the downregulated pathways and genes, respectively. The red circles and arrowheads depict the upregulated pathways and genes, respectively. The bigger size squares and circles denote the lower p-value. An increase in the color transparency (lighter color) of the squares and circles indicates an increase in the percentage of the included genes with expression that counter the regulation direction of the pathway. C. The top significant KEGG pathways of HSc vs. HSi, the comparison between the chickens infected with Eimeria maxima raised under HS (HSi) and their uninfected HS control (HSc) at 6 day-post-treatment. D. The top significant Gene Ontology terms of HSc vs. HSi, the comparison between the chickens infected with Eimeria maxima raised under HS (HSi) and their uninfected HS control (HSc) at 6 day-post-treatment.</p
Fig 3 -
No full textA. Heatmap of the top ~60 DEGs of TNc vs. TNi, as Log 2 relative hit counts of the comparison between the chickens infected with Eimeria maxima (TNi) and their uninfected thermoneutral control (TNc) at 6 day-post-treatment. B. The top KEGG pathways of TNc vs. TNi, based on the pathway term significance (α≤0.1) of the comparison between the chickens infected with Eimeria maxima (TNi) and their uninfected thermoneutral control (TNc) at 6 day-post-treatment. The green squares and arrowheads depict the downregulated pathways and genes, respectively. The red circles and arrowheads depict the upregulated pathways and genes, respectively. The bigger size squares and circles denote the lower p-value. An increase in the color transparency (lighter color) of the squares and circles indicates an increase in the percentage of the included genes with expression that counter the regulation direction of the pathway. C. The top significant KEGG pathways of TNc vs. TNi, the comparison between the chickens infected with Eimeria maxima (TNi) and their uninfected thermoneutral control (TNc) at 6 day-post-treatment. D. The top significant Gene Ontology terms of TNc vs. TNi, the comparison between the chickens infected with Eimeria maxima (TNi) and their uninfected thermoneutral control (TNc) at 6 day-post-treatment.</p
The top 100 DEGs (50 downregulated and 50 upregulated) of TNi vs. HSi.
No full textThe top 100 DEGs (50 downregulated and 50 upregulated) of TNi vs. HSi.</p
Standardized factor loadings, unstandardized factor loadings, and standard errors for items of the Spanish version of the MARS-12.
No full textStandardized factor loadings, unstandardized factor loadings, and standard errors for items of the Spanish version of the MARS-12.</p
Study flow diagram.
No full textOutcome indicates requirement of HFNC, Non-Outcome indicates no requirement of HFNC. HFNC: high-flow nasal cannula; COVID-19: coronavirus disease 2019.</p