Health Leadership and Quality of Life (Journal)
Not a member yet
733 research outputs found
Sort by
The Role of Nanoparticles in Wound Healing: Synthesis, Characterization, and Mechanisms of Action
Full text linkAs a consequence of its distinctive functioning and diverse set of uses, nanotechnology is a discipline that is expanding quickly. To prevent, cure, diagnose, and control illness, nanomedicine examines the potential applications of nanotechnology knowledge and techniques. Silver nanoparticles with a length between 1 to 100 mm are thought to be the most important in this aspect because of their exceptional property, ability that form different nanostructures, incredible group for antibacterial effects, the space for wound healing and other beneficial ability, and efficiency in production. Research analysis the different biological, chemical, and physical techniques for nanoparticles development are explored. The techniques to employ silver nanoparticles as antibacterial substances, anticancer, in dentistry and bone healing promoter, in wound healing supporters are presented. Research examines the purpose of silver nanoparticles in medical therapies and illness management by examining their method of accomplishment, synthesis techniques characterization
Harnessing Special Interests: A Strength-Based Framework for Enhancing Interventions in Autism Spectrum Disorder
Full text linkIntroduction: Traditional interventions for children with autism spectrum disorders (ASD) focus primarily on correcting deficits, often ignoring the unique strengths and intrinsic motivation of the individual. One such underutilized strength is special interests, highly focused passions that are both common and unique among individuals with ASD. Emerging insights suggested that incorporating these special interests into intervention strategies can significantly enhance engagement, skill acquisition, and overall treatment outcomes.
Methods: Employed a theoretical construction method using literature review, inductive reasoning, and model development. It reviewed the relevant literature, and the findings were then distilled through an inductive process to develop a generalizable practical framework.
Results: A novel conceptual framework was proposed, repositioning SIs as foundational elements of intervention design. This framework outlined a five-stage process: (1) identification of special interests, (2) alignment of therapeutic goals with interests, (3) integration across multiple domains, (4) enhanced engagement and motivation, and (5) improved skill acquisition and emotional well-being. Furthermore, five practical application modules were presented: an integrated learning module, a peer-mediated module, a creative expression module, a technology-assisted module, and a family-centered module.
Conclusions: Reframing special interests as therapeutic assets rather than barriers offered a promising direction for intervention. This framework suggested a move toward more individualized, empowering, and effective interventions for individuals with ASD
Considerations about the importance of physical exercise in people\u27s health and well-being
No full textIntroduction: Physical exercise is any physical activity that improves and maintains a person\u27s physical fitness, health and well-being. It is carried out for various reasons, such as muscle strengthening, improving the cardiovascular system, developing athletic skills, fat loss or maintenance, emotional well-being as well as recreational activity.Objective: characterize the effect of physical exercise on people\u27s health and well-being.Method: a review of the literature available in databases such as SciELO, Scopus and ClinicalKey was carried out, of which a total of 15 related articles were consulted, empirical methods such as logical history and analysis and synthesis were used. Results: physical activity is considered the factor that intervenes in the state of people\u27s health. The constant practice of physical exercise improves and strengthens the immune system, helping to preserve the integrity of the cells in the body. During the first years of life it can make a difference in terms of the good condition of the bone system, cardiovascular resistance, and lower blood pressure. , overweight and obesity. The practice of physical activity is also seen to be related to reducing symptoms of fatigue, stress, depression and increasing self-esteem and improving mood. Conclusions: physical exercise is presented as an essential tool to achieve a healthier, happier and fuller life. Regardless of age or physical condition, exercise can be adapted to individual needs, becoming an investment in your long-term health and well-being
Occupational risks in workers of CADE food industry and the Montúfar Battalion, Santo Domingo
Full text linkIntroduction: occupational risk is any circumstance capable of causing danger in the context of the development of an activity within the work day.Objective: identify the occupational risks to which workers in the CADE food industry and the Montúfar Battalion are exposed, Santo Domingo, 2022.Methods: observational, descriptive cross-sectional research. The universe was 100 people and through non-probabilistic sampling for convenience and the established exclusion and inclusion criteria, the sample was made up of 59. The data were tabulated through Microsoft Excel for better study and understanding.Results: Regarding the working hours of the respondents, it was established that 44,8 % worked more than 40 hours and 27,6 % worked 20 to 40 hours and less than 20 hours; In the battalion, 63,3 % work between 20 to 40 hours and 36,7 % work more than 40 hours. It was determined that 48,3 % of the sample in the Cadepan industry considers noise to be high and 41,4 % establishes that there is no noise; while in the battalion 96,7 % of workers are exposed to high noise.Conclusions: raising awareness of the personnel who work in both institutions on topics such as the proper use of equipment and tools specific to the area is a first-order task, in addition, adopting correct work postures to avoid health problems in the futur
Comparative study of the use of antihypertensives and their relationship with sars-cov-2
Full text linkThis comparative study analyzed the published scientific evidence about the association between the reduction of severity or mortality due to COVID-19, and the efficiency of the use of Angiotensin Converting Enzyme Inhibitors (ACEIs) and angiotensin receptor blockers (BRAs) compared to other drugs antihypertensives non-ACEI/ARB in hypertensive patients. The objective was to estimate the occurrence of the risk of morbidity, severity or mortality due severe acute respiratory failure in hypertensive patients and the efficacy of angiotensin-converting enzyme (ACE) and inhibitor drugs non-peptic Angio II receptor antagonists (ARBs II) in SARS-Cov-2.The methodology used was the exhaustive bibliographic review of literary bases through the advanced search function of observational studies, clinical trials and meta-analyses that focus on the use of ACE Inhibitors/BRAs in SARS-Cov-2.The ACEI and ARB results demonstrated better efficacy in terms of control of inflammatory processes and low risk of severity due to COVID-19 than CCBs. In addition, several studies affirm that there is a low risk of hospitalization, intubation and mortality from all cardiovascular causes during COVID-19 disease. Therefore, published scientific evidence suggests acceptable safety of the management of ACEIs/ ARBs in SARS-Cov-2 and arterial hypertension in contrast to the few studies where ACEIs / ARBs increased the susceptibility of SARS-Cov-2, resulting in potential systemic damage. Conclusion: The medium-low quality of scientific evidence suggests an urgent need for a new systematic review that includes a greater number of randomized clinical trials, to corroborate the magnitude of the risk of morbidity, severity, and mortality from SARS-Cov-2
Emergency stock in a resource-constrained acute care unit: analysis of the medication management process
Full text linkIntroduction: The research is based on the evaluation and analysis of drug stock management in the Emergency Department of Peltier University Hospital Center in Djibouti. Methods: An observational, longitudinal and descriptive study was conducted from December 1, 2023 to April 30, 2024. The aim was to describe the diseases with the highest incidence in the emergency department and to organize a stock of medicines. Results: the health problems that contributed the greatest number of patients were cerebrovascular diseases and renal failure with a length of stay of 27 and 66 hours respectively. In relation to the stages of drug acquisition management, it was possible to analyze that, although there are most of the drugs in the institution, their use and consumption is deficient since there is no physical or documented existence of a stock of drugs in the emergency department, which is expressed in the prolongation of the stay in the service. A medication guide was developed to improve the emergency stock and better patient management. Conclusions: The lack of a stock of medicines in the emergency department affected the stage (use - consumption), which is the most important for the adequate management of the patient, thus prolonging the stay in the servic
Conceptual aspects of public administration of the quality of life in the context of war
Full text linkIntroduction: post-COVID syndrome is associated with a wide range of long-term complications, among which neurological manifestations have become increasingly recognized. These complications present diagnostic and therapeutic challenges due to their heterogeneity and the evolving understanding of their pathophysiology.Objective: to investigate the clinical and pathogenetic characteristics of neurological manifestations in patients with post-COVID syndrome, with a focus on identifying patterns and potential underlying mechanisms.Methods: a cohort of 60 patients with confirmed post-COVID syndrome was evaluated. Clinical assessments included neurological examination, neuroimaging (MRI), and neurophysiological studies (EEG, EMG, and evoked potentials). Laboratory markers were also analyzed to assess inflammatory and autoimmune activity. Data were categorized by symptom type and severity.Results: The most frequent neurological symptoms were headaches (48.3%), cognitive impairments (41.6%), sleep disorders (40%), and anxiety-depressive symptoms (38.3%). Neuroimaging revealed structural changes in 35% of patients, while neurophysiological testing showed signs of central and peripheral dysfunction in a significant subset. Laboratory analysis indicated elevated inflammatory markers in patients with more severe neurological presentations. Findings suggest a multifactorial pathogenesis involving neuroinflammation, vascular dysfunction, and possible autoimmune responses.Conclusions: The most frequent neurological symptoms were headaches (48.3%), cognitive impairments (41.6%), sleep disorders (40%), and anxiety-depressive symptoms (38.3%). Neuroimaging revealed structural changes in 35% of patients, while neurophysiological testing showed signs of central and peripheral dysfunction in a significant subset. Laboratory analysis indicated elevated inflammatory markers in patients with more severe neurological presentations. Findings suggest a multifactorial pathogenesis involving neuroinflammation, vascular dysfunction, and possible autoimmune responses
Safety and health risks and opportunities in generating sets in Pinar del Río
Full text linkAn efficient identification, evaluation and registration of occupational risks implies avoiding or minimizing the causes of accidents and diseases derived from work. Organizations must give equal importance to the management of these risks as a fundamental aspect for the correct development of their business activity. For this reason, this research aims to update the occupational risk management of the Geysel Pinar del Río Base Business Unit, based on current international standards. Methods and tools such as direct observation, brainstorming, checklist, radar graph and double entry matrix were used. The initial diagnosis reflected the state of maturity of the Health and Safety System currently implemented, and based on this, actions were carried out to address the risks and opportunities that guaranteed proactive management
A Comprehensive Analysis of the Relationship Between Polycystic Ovary Syndrome and Anxiety
Full text linkBackground: Polycystic Ovary Syndrome (PCOS) is a reproductive, metabolic, and psychiatric endocrine disorder. The increasing evidence points toward the firm relationship between PCOS and anxiety but does not identify the underlying relationships.Aim: To investigate the relationship between PCOS and anxiety, evaluating potential causative factors including hormonal deregulation, metabolic imbalance, and markers of inflammation.Methods: The research involved 250 women participants were recruited, 150 with PCOS (experimental group) and 100 controls. Anxiety was measured by a validated questionnaire for anxiety. Hormonal and metabolic variables, such as insulin resistance (HOMA-IR), testosterone, BMI, and C-reactive protein (CRP), were measured and correlated with anxiety scores. Statistical tests were utilized to establish significant differences and correlations.Results: The evidence favours hormonal dysregulation, metabolic derangement, and systemic inflammation as the etiopathogenic factors in anxiety in PCOS patients. Hyperandrogenism and insulin resistance are associated with neuro-chemical alterations in mood control, while systemic inflammation is associated with increased psychological distress. These physiological changes could be the intrinsic factors for increased incidence of anxiety in PCOS.Conclusion: The research identifies a high level of correlation between PCOS and anxiety, with insulin resistance, elevated testosterone, BMI, and inflammation being significant contributory factors. Intervention in these variables is helpful in improving mental health outcomes among PCOS patients. Longitudinal trends and possible therapeutic options for decreasing anxiety in this group should be the focus of future studies
Hepatitis B Incidence in Individuals with Chronic Kidney Disorder: A Meta-Analysis
Full text linkThe hepatitis B virus is a major contributor to liver disease and has many non-liver symptoms. In addition to the significant impairment and mortality that HBV causes in the population, the most recent study indicates the role that HBV plays in the initiation and development of Chronic Kidney Disease (CKD). The causal relationship between HBV and CKD has yet to be fully elucidated. Antiviral nucleos (t) medicine compounds for HBV are already available, and they are very effective for individuals with chronic kidney disease. An increased probability of CKD has been identified in those with HBV, according to a recent meta-analysis of clinical data. Based on the most recent review, we identified six separate clinical trials. There was too much variation to draw any firm conclusions. Several proposed reasons account for the increased risk of CKD in HBsAg optimistic patients. Additional data links treatment with nucleos(t)ide equivalents to a decreased risk of end-stage renal disease (ESRD) and links undiagnosed HBV to an increased risk of ESRD in the CKD population. They advise that kidney activity and urine alterations be measured at the outset and periodically in HBV participants