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A Qualitative Study on Remote Workers' Work-Life Balance Uzaktan Çalışanların İş-Yaşam Dengesi Üzerine Nitel Bir Araştırma
No full textThis study examines the relationship between remote work, a flexible working arrangement, and work-life balance using a qualitative research approach. While existing literature focuses on the link between work-life balance and traditional work structures, this research adopts a sceptical perspective on the flexibility offered by remote work in terms of time and space. It explores how these types of flexibility relate to work-life balance. Drawing on theoretical frameworks, the study questions whether remote work genuinely blurs the physical and temporal boundaries between professional and personal life within a cause-and-effect research design. Overall, it finds a gap between theoretical assumptions and practical outcomes
Ailelerin Çevreye Yönelik Davranışlarının Çocuk Sağlığı ile İlişkisi: Kesitsel Bir Çalışma
No full texthealth. Materials and Methods: This descriptive, cross-sectional study was conducted with parents across the country whohave children and live in the same household. Data were collected using a Family Information Form and an EnvironmentalBehavior Scale (EBS). Parents from various regions nationwide were included in the study. Data were analyzed at a 95%confidence interval. Results: The study was completed with 616 mothers, with an average age of 35.7 years. It wasdetermined that most families resided in developed and highly urbanized regions. Children were reported to be ill one to fourtimes per year, most commonly with acute respiratory system diseases. The families’ mean EBS score was 66.2, indicatingan above-average level of environmental behavior. A significant difference was found between Environmental BehaviorScale scores and the region of residence. Conclusion: It is suggested that the incidence of acute or chronic diseases decreasesamong children who grow up in environmentally friendly settings, allowing for a healthier interaction between people andthe planet. Human activities must be aligned with environmental harmony not only to protect human health but also to ensurea sustainable ecosystem overall</p
Development of Bigels Using Citrus Fiber and Beeswax: Application in Cocoa Spread Formulation as Palm Oil Alternative
No full textIn this study, bigel systems were developed as potential alternatives to palm oil in cocoa spreads. This study developed citrus fiber (CF)-based bigel systems as alternatives to palm oil in cocoa spreads. Bigels were formulated by combining hydrogels (HG) containing CF (5% and 7.5%) with olive oil oleogels (OG) structured using 10% beeswax at different HG:OG ratios (80:20, 50:50, and 20:80). All bigels exhibited higher storage (G′) and loss (G″) moduli than palm oil, indicating enhanced viscoelastic behavior. Increasing the oleogel fraction improved the structural integrity of the bigel network. Bigels containing 7.5% CF were incorporated into cocoa spreads, where higher oleogel ratios increased the solid character (G′). All bigel-enriched cocoa spreads showed thixotropic behavior with lower deformation and higher structural recovery compared to palm oil-based spreads. Additionally, bigel addition improved temperature-dependent stability. These results demonstrate that CF-based bigels provide a compact, viscoelastic, and stable fat system, highlighting their potential as palm oil replacers in cocoa spread formulations
Real-world effectiveness and safety of brigatinib in advanced ALK-positive NSCLC: a nationwide multicenter study by the Turkish Oncology Group
No full textBackground: Brigatinib, a next-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor, has demonstrated efficacy in pivotal trials in both pretreated and treatment-naïve patients with ALK-positive non-small-cell lung cancer (NSCLC). However, real-world evidence from large multicenter cohorts remains limited. Methods: We conducted a retrospective multicenter study including 114 patients with advanced ALK-positive NSCLC treated with brigatinib across 28 centers in Turkey between May 2020 and December 2024. Objective response rate (ORR) was assessed by RECIST v1.1. Median progression-free survival (mPFS) and overall survival (mOS) were estimated by the Kaplan–Meier method, and prognostic factors were analyzed using Cox regression. Results: The median age was 55 years. Brigatinib was administered as first-line therapy in 68.4% of cases. In the overall cohort, the mPFS and OS were 24.2 and 44.2 months. The ORR was 70.2%. In the first-line setting, the ORR was 79.5%, with an mPFS of 28.6 months and an mOS of 50.3 months. In contrast, those treated in the second-line or later setting had less-favorable outcomes, which independently correlated with worse OS in multivariate analysis. Patients with baseline brain metastases achieved favorable outcomes, with an mPFS of 26.2 months, an mOS of 46.3 months, and an ORR of 76.5%. Adverse events were reported in 83.3% of patients, most commonly gastrointestinal toxicities, creatine phosphokinase elevation, and liver enzyme abnormalities. Conclusion: This nationwide multicenter study offers comprehensive real-world evidence confirming the effectiveness and tolerability of brigatinib in ALK-positive NSCLC, with especially favorable outcomes in the first-line setting and in patients with brain metastases
A Real-Time Traffic Violation Detection System on Highways Using Surveillance Cameras and Message-Oriented Middleware
No full textThe rapid growth in the number of vehicles has intensified traffic congestion and increased the frequency of traffic violations, which remain a major contributing factor to severe accidents, particularly on highways, where high-speed collisions often result in substantial loss of life and property. Therefore, the early, accurate, and automated detection of such violations is crucial for enhancing traffic safety. This study presents a real-time violation detection system designed to identify critical highway infractions, including reversing vehicles, illegally stopped vehicles in the right lane, and unauthorized presence of pedestrians or animals on the roadway. The proposed framework employs an image processing pipeline integrated with a distributed event-driven architecture. Using a topic-based publish/subscribe messaging model built on Apache Kafka, the system efficiently disseminates detected violation events and corresponding visual evidence to authorized units in real time. The architecture is scalable and extensible, enabling the incorporation of additional violation types and analytical modules with minimal system reconfiguration. Experimental evaluations demonstrated that the system achieved reliable detection accuracy under appropriate camera placement and operational conditions, offering a practical foundation for next-generation intelligent transportation and traffic enforcement systems
New monolithic post-core concept: a comparison of prefabricated and CAD-CAM fabricated post-cores.
No full textEffect of Tincal Particle Reinforcement on the Tribological Behaviors of Polyester and Vinyl Ester Composites
No full textComposite materials, widely utilized across diverse industries, comprise various reinforcement phases (fibrous or particulate) and matrix phases (polymeric, ceramic, or metallic). However, thermoset polymers, notably polyester and vinyl ester resins, may experience a decrease in strength over time. This wear-induced weakening renders materials susceptible to external factors, leading to structural damage. To mitigate these effects, research has often focused on resin modification, frequently involving the incorporation of particles. These particles enhance the material's wear resistance when integrated into the resin matrix. However, studies on the wear behaviors of polyester and vinyl ester resins are limited. This study experimentally investigated the wear properties of polyester and vinyl ester resins reinforced with tincal particles. Results showed that the addition of tincal improved the wear performance of both resins. For vinyl ester, the optimal enhancement occurred at 1 wt% tincal, resulting in a reduction of the coefficient of friction by ∼30% and an improvement in wear resistance by about 20%. Polyester composites exhibited a steady progress up to 3 wt% tincal, resulting in nearly 40% lower friction compared to the pure resin. Scanning electron microscopy (SEM) analysis confirmed smoother worn surfaces and fewer grooves in tincal-filled samples. These findings highlight tincal as a cost-effective, naturally abundant filler that enhances the tribological durability of thermosetting resin composites
COGNITIVE LOAD AND LEGAL RESPONSIBILITY IN SMART MARITIME LOGISTICS: THE HUMAN FACTOR UNDER PRESSURE
No full textPurpose: Smart logistics technologies, such as AI-assisted decision systems and IoT-based cargo monitoring systems, are increasingly integrated into maritime operations, as they are becoming the new normal among maritime operations. While these systems aim to minimise human error and optimise performance as they focus on accuracy and efficiency, they also simultaneously impose new psychological burdens on seafarers and logistics personnel. The expectation to override, monitor, or validate machine outputs creates a high-stress environment where the boundaries of legal responsibility become blurred. Study design/methodology/approach: This study explores how increasing cognitive load in smart maritime logistics environments affects human decision-making and legal responsibility. While automation enhances operational efficiency, it also brings new forms of psychological pressure, expecting seafarers to stay alert, make judgment calls, and be accountable even when working alongside AI systems. Drawing from maritime law, psychology, and business administration, this paper argues that current legal frameworks fall behind these technological changes. Emotional fatigue, decision-making stress, and mental workload are rarely considered in liability assessments. Using a qualitative, interdisciplinary approach, the research combines legal analysis with human factors literature, supported by case studies and references to the Turkish Commercial Code, MLC 2006, and IMO instruments. Findings: Ultimately, the analysis highlights that legal frameworks governing maritime logistics must evolve with technological advancements by addressing structural risks introduced by automation and acknowledging the psychological vulnerabilities of the human element. Originality/value: The paper’s originality lies in framing psychological vulnerability not as individual weakness, but as a systemic blind spot in maritime law, calling for a more human-centred understanding of legal responsibility in an era increasingly shaped by automation. KEYWORDS Smart Logistics, Cognitive Load, Human Factor, Liability in AI Systems, Human-Centred Regulation, Maritime Labour Law. RELATED TOPICS Artificial Intelligence in logistics and supply chains, Transportation and logistics law, Humanitarian logistics and supply chains. </p
Error bounds of Boole’s formula for diverse function classes: Implications for Riemann–Liouville fractional integrals and numerical analysis
No full textIn numerical analysis, Boole’s formula is a key tool for approximating definite integrals. Accurate approximation of these integrals is vital in numerical methods for solving differential equations, especially in the finite volume method, where high-quality integral approximations lead to improved results. This paper provides rigorous proof of integral inequalities for first-time differentiable convex functions within the context of fractional calculus. We begin by establishing an integral equality that involves fractional integrals, subsequently deriving Boole’s formula-type inequalities for differentiable convex functions. This study examines important functional classes, including convex functions, Lipschitzian functions, bounded functions, and functions of bounded variation. Furthermore, we demonstrate the efficiency of derived inequalities through graphical representations, illustrating their application to specific functions and emphasizing their precision in approximating definite integrals