Czasopisma Uniwersytetu Przyrodniczy w Lublinie
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Hyperthermic Intraperitoneal Chemotherapy: A Holistic Investigation of Global Outputs with Bibliometric Analysis
No full textBackground: Hyperthermic intraperitoneal administration of chemotherapy (HIPEC) targets microscopic residues remaining after complete cytoreduction. Objectives: We systematically presented the development process of the HIPEC treatment regimen, the most remarkable publications on this topic, the most productive countries, and the future of treatment in the coming years. Methods: The source of our study was the Web of Science (WoS) database which included the Korean Journal Database, core collection index, Russian Science Citation Index, and Sci ELO citation index. Results: We reached a total of 3,343 publications by analyzing the WoS database using the keyword of Hyperthermic intraperitoneal chemotherapy. When the citations of the documents written about HIPEC were evaluated, we found that the highest citation was made in 2019. Co-citation analysis showed that there were 27,724 authors investigating the issue of HIPEC. The most active university was determined as Wake Forest University, USA. Collaboration and citation collaboration was observed between Wake Forest University, the University of Pittsburgh, and the University of Texas. The intersection point of all researcher countries was the USA. While reviewing the articles on HIPEC, we also identified new trends and topics in this regard. Ovarian cancers, gastric cancers, and colorectal cancers were found to be the types of cancer that had the strongest relationship with HIPEC. Conclusion: HIPEC therapies should be considered an area of research that has been studied, published, and cited by surgeons, oncologists, and pharmacologists interested in the treatment of tumors with peritoneal spread
Total quality management approach in the strategic plans of state universities in Turkey: Example of TRB-1
No full textGünümüzde özel kurumlarda artan rekabet koşullarının devlet kurumlarında da etkili olması, Türkiye'de devlet üniversitelerinin üstlendikleri sorumlulukların kapsamını genişletmekte ve Yeni Kamu Yönetimi (YKY) anlayışının temel unsurlarını benimsemelerini gerekli kılmaktadır. Stratejik plan ve Toplam Kalite Yönetimi anlayışına yönelik uygulamalar, YKY anlayışının Türkiye'de devlet üniversitelerine yansımaları olarak değerlendirilebilir. Türkiye'de devlet üniversitelerinin, stratejik planlarında Toplam Kalite Yönetimi anlayışı hakim kılınmak isteniyorsa; stratejik kararların alınması ve hayata geçirilmesinde Toplam Kalite Yönetimi anlayışının temel ilkelerinin uygulanması gerekmektedir. Türkiye'de devlet üniversitelerinde söz konusu çalışmaların başlatılması "5018 Sayılı Kamu Mali Yönetimi ve Kontrol Kanunu" ile gerçekleşmiş ve üniversitelerce hazırlanan stratejik planların her aşamasında önem teşkil eden kalite politikalarının, stratejik hedeflerle bağlantılı ve örgütün bütün birim ve bölümlerini kapsayacak şekilde uygulamaya geçirilmesi sağlanmıştır. Üniversitelerde Toplam Kalite Yönetimi ilkelerinin benimsenmesi, örgütsel performansı yansıtan temel belirleyici faktörler arasında sayılmaktadır. Araştırmada üniversitelerin performans hedeflerine ulaşmasındaki temel güç kaynağını oluşturan; liderlik, sürekli gelişme, müşteri odaklılık ve katılımlı yönetim ilkelerinden yararlanılmaktadır. Bu anlamda stratejik plan ve Toplam Kalite Yönetimi anlayışı birlikte ele alınmakta ve TRB-1 Bölgesi Üniversitelerinin stratejik planlarındaki Toplam Kalite Yönetimi anlayışı söz konusu ortak göstergeler ölçeğinde incelenmektedir. Araştırma sonucunda elde edilen bulgular göstermektedir ki TRB-1 Bölgesi Üniversitelerinin stratejik planlarının yalnızca farklılaşma stratejisi aşamasında Toplam Kalite Yönetimi anlayışına yönelik liderlik ilkesine rastlanmamış, bunun dışında araştırmaya konu olan stratejik planların incelenen aşamalarında temel belirleyici göstergelerden en az birine rastlanmıştır. Bu nedenle TRB-1 Bölgesi Üniversitelerinin stratejik planlarında Toplam Kalite Yönetimi anlayışı; liderlik, sürekli gelişme, müşteri odaklılık ve katılımlı yönetim ilkeleri bağlamında uygulanmıştır demek mümkündür. Anahtar kelimeler: Strateji, Stratejik Plan, Toplam Kalite Yönetimi, TRB-1 Bölgesi, ÜniversiteToday, the increasing competitive conditions in private institutions are also effective in public institutions, expanding the scope of the responsibilities undertaken by state universities in Turkey and necessitating them to adopt the basic elements of the New Public Management (NPM) approach. Strategic planning and practices for Total Quality Management can be considered as reflections of the NPM approach to state universities in Turkey. If a Total Quality Management approach is desired to be dominant in the strategic plans of state universities in Turkey; It is necessary to apply the basic principles of Total Quality Management approach in taking and implementing strategic decisions. The initiation of such studies in state universities in Turkey was realized with the Public Financial Management and Control Law No. 5018, and it was ensured that the quality policies, which are important at every stage of the strategic plans prepared by the universities, are implemented in a way that is related to strategic goals and covers all units and departments of the organization. The adoption of Total Quality Management principles in universities is considered among the main determining factors reflecting organizational performance. In the research, the main power source for universities to reach their performance targets; leadership, continuous improvement, customer orientation and participatory management principles are used. In this sense, the strategic plan and the Total Quality Management approach are considered together and the Total Quality Management understanding of the TRB-1 Region Universities in the strategic plans is examined on the scale of these common indicators. The findings obtained as a result of the research show that the leadership principle for Total Quality Management approach was not encountered only in the differentiation strategy stage of the strategic plans of the TRB-1 Region Universities, apart from that, at least one of the main determining indicators was encountered in the examined stages of the strategic plans that are the subject of the research. For this reason, the understanding of Total Quality Management in the strategic plans of TRB-1 Region Universities; It is possible to say that it has been implemented in the context of leadership, continuous improvement, customer orientation and participatory management principles. Key words: Strategy, Strategic Plan, Total Quality Management, TRB-1 Region, Universit
EFFECTS OF GAZE POSITION ON OCULAR VESTIBULAR EVOKED MYOGENIC POTENTIAL (oVEMP)
No full textPurpose:To compare ocular vestibular evoked myogenic potential (oVEMP) responses obtained with superomedial and oblique gaze positions. Material and Methods:The oVEMP test was applied in 59 healthy subjects at superomedial, right oblique, and left oblique gaze positions. Stimuli were presented at 110 dB nHL with a frequency of 500 Hz. oVEMP responses were recorded via electrodes placed on the lower eyelids. Results:Higher N1-P1 amplitudes were obtained in oblique gaze positions in the stimulated ear direction compared to the superomedial position (p < 0.05). The asymmetry values obtained in the superomedial gaze position were lower than those obtained in oblique gaze positions (p < 0.05). The asymmetry values obtained in the Superomedial and oblique gaze positions had no effect on the N1, P1, and N1-P1 latencies of the waves obtained from the Conclusion:Superomedial and oblique gaze positions affect oVEMP waves. In patients in whom vestibular hypofunction is suspected, it is recommended to control oVEMP responses in oblique gaze positions as well as in superomedial gaze positions in the evaluation of the residual vestibular functions
Mapping Publication Status and Exploring Hotspots in a Research Field: Breastfeeding
No full textBackground: Breastfeeding has been the subject of scientific studies for many years. Identifying the current trends and hotspots in breastfeeding research can further advance understanding in the field. Research Aim: This study aimed to review the basic and conceptual structure of the literature on breastfeeding from a macro perspective. Methods: The dataset for this study included 8,509 articles published between 1980 and 2022 accessed through the Web of Science database. Bibliometric methods were used to assess the growth direction of the literature on breastfeeding, the publication performance by country, influential journals and articles, co-citation networks, and keywords. Results: Research on breastfeeding developed slowly until the 2000s, at which point the speed of growth increased. The United States was the country in which most of the breastfeeding research was produced as well as being at the center of international collaborative networks. An examination of author productivity established that there was no specialization in breastfeeding. The results of citation and keyword analyses demonstrated that the literature on breastfeeding is sensitive to current developments, and the psychological aspects of breastfeeding have been intensively discussed, especially in recent years. Moreover, our results demonstrate that breastfeeding support programs are a distinct area if interest. Despite the abundance of research available, more studies are needed for specialization in this field. Conclusion: This broad overview of the field of breastfeeding research can inform the direction and advancement of the literature
Characterization of new late-spring-frost-tolerant apricot hybrids: physical and biochemical fruit quality attributes, volatile aroma compounds
No full textLate spring frosts is one of the most important restricting abiotic stress factors of apricot growing worldwide. In this study; some physical, biochemical fruit quality characteristics and volatile aroma compounds were determined in fresh fruit samples of thirteen late spring frost tolerant apricot hybrids recently obtained from Turkish apricot breeding programme. A wide variation was reported among apricot genotypes in all of the evaluated physical and biochemical fruit characteristics and also volatile aroma compounds. Fruit size varied between 27.2 and 60.5 g, total soluble solids between 13.6 and 17.4 %, total carotene 26.6 and 42.8 (mg.100 g-1), and total phenolics content 354.2 and 673.1 (GAE.100 g-1). A total of 42 flavor components belonging to various flavor compound groups were identified. The main volatile aroma compound groups detected in the assessed apricot genotypes were; aldehydes, ketones, esters, alcohols, terpenes, acids, and other compounds. Among the detected compounds; Hexanal, 2-Hexenal, 1-Hexanol, 2-Hexen-1-ol, Limonene were the most abundant compounds in terms of concentration. Hexanal varied between 55.8 and 528.5 mu g.kg-1, and 2-Hexen-1-ol changed between 25.7 and 297.9 mu g.kg-1 fresh weight. Correlation analysis revealed significant correlations among some aroma compounds and biochemical fruit quality characteristics. Significant correlations were reported for esters with titratable acidity (r=0.79) and total carotene (r=-0.61) and aldehydes were found as highly correlated with total soluble solids (r=-0.69). The results of the study will be beneficial in terms of food analysis, cultivation, and breeding studies of apricot.Scientific Research Projects Coordination Department of Inonu University [FYL-2016/112YLisans]We thank Dr. Sahin Anil for his valuable revision and improvement of the manuscript. This research was supported by Scientific Research Projects Coordination Department of Inonu University (FYL-2016/112YLisans)
Investigation of the relationship between emotional abuse of adolescents by their parents and social media addiction
No full textAmaç: Ergenlerin Ebeveynleri Tarafından Maruz Kaldığı Duygusal İstismar ile Sosyal Medya Bağımlılığı Arasındaki İlişkinin İncelenmesi amacıyla yapılmıştır. Materyal ve Metot: Araştırma kesitsel olarak yapılmıştır. Araştırmanın evrenini Malatya İli Yeşilyurt ilçe merkezinde bulunan liselerden kura yöntemiyle seçilen beş lisede Ekim 2021 ile Mart 2023 tarihleri arasında yürütülmüştür. 13-18 yaşları arasında 428 ergen katılmıştır. Veriler; tanıtıcı özellikler formu, Ergenler için Algılanan Duygusal İstismar Ölçeği ve Ergenlerde Sosyal Medya Bağımlılığı Ölçeği kullanılarak toplanmıştır. Verilerin analizinde (SPSS) 26.0 paket programı, değerlendirilmesinde normallik varsayımı Kolmogorov- Smirnov, Shapiro- Wilk testleri, mann-Whitney U testi, Kruskal Wallis testi, Dunn- Bonferroni çoklu karşılaştırma testi kullanılmıştır ve Sperman Brown korelasyon katsayısı hesaplanması için kullanılmıştır. Bulgular: Araştırmada algılanan duygusal istismar–Anne formu düzeyinde (57.85±19.14) toplam puan, algılanan duygusal istismar–Baba formu düzeyinde (56.98±20.09) toplam puan, sosyal medya bağımlılık düzeyinde ise (5.68±2.40) toplam puan değeri elde edilmiştir. Ayrıca sosyal medya bağımlılığı ile anneden algılanan şiddetli ret, Gizli ret, Gerçekçi olmayan beklentiler, aşağılama alt boyutları ve toplam duygusal istismar puanları arasında negatif yönde, Kabul saygı alt boyutu ile pozitif yönde istatistiksel olarak önemli (p<0.05) ilişkiler saptanmıştır. Sosyal medya bağımlılığı ile babadan algılanan şiddetli ret, gizli ret, gerçekçi olmayan beklentiler, aşağılama alt boyutları ve toplam duygusal istismar puanları ile arasında negatif yönde, kabul saygı alt boyutu ile pozitif yönde istatistiksel olarak (p<0.05) önemli ilişkiler saptanmıştır. Sonuç: Bu çalışmada ergenlerin ebeveynleri tarafından maruz kaldığı duygusal istismar ile sosyal medya bağımlılık düzeyleri arasında şiddetli ret, gizli ret, gerçekçi olmayan beklentiler, aşağılama ve kabul/saygı alt boyutlarında istismar arttıkça sosyal medya bağımlılığı azalıyor olduğu saptanmıştır. Anahtar Kelimeler: Algılanan Duygusal İstismar, Ergen, Halk Sağlığı Hemşireliği, Sosyal Medya Bağımlılığı.Aim: This research was conducted to examine the relationship between emotional abuse of adolescents by their parents and social media addiction. Material and Method: The research was done by cross-sectional. The universe of the research consists of five high schools selected by lot between November 2021 and December 2022 in Malatya Province Yeşilyurt district center. 428 adolescents between the ages of 13-18 participated to the study. Data were collected using the descriptive characteristics form, the Perceived Emotional Abuse Scale for Adolescents (ASDS), and the Adolescent Social Media Addiction Scale (SMDS). The 26.0 package program (SPSS) was used in the analysis of the data, the normality assumption Kolmogorov- Smirnov, Shapiro- Wilk tests, the mann-Whitney U test, the Kruskal Wallis test, the Dunn- Bonferroni multiple comparison test were used in the evaluation, and the Sperman Brown correlation coefficient was used for calculation. Results: The total score at the perceived emotional abuse–mother form (57.85±19.14), the total score at the perceived emotional abuse–father form (56.98±20.09), and the social media addiction level (5.68) A total score of ±2,40) was obtained. In addition, negative correlation between social media addiction and perceived severe rejection from the mother, covert rejection, unrealistic expectations, humiliation and total emotional abuse scores and (p<0.05) positive correlation with acceptance respect sub-dimension statistically significant relationships were detected. There was a negative correlations between social media addiction and perceived severe rejection from the father, covert rejection, unrealistic expectations, humiliation sub-dimensions and total emotional abuse scores, on the other hand, statistically significant (p<0.05) correlations were detected on posititive direction with the acceptance-respect sub-dimension. Conclusion: In this study, it was determined that social media addiction decreases as the abuse increases in the sub-dimensions of severe rejection, hidden rejection, unrealistic expectations, humiliation and acceptance/respect between the emotional abuse that adolescents are exposed to by their parents and their social media addiction levels. Key Words: Perceived Emotional Abuse, Adolescent, Public Health Nursing, Social Media Addiction
Examining The Rules in Nuclear and Origin Families Living in Turkey
No full textThis study aimed to examine married couples’ descriptions of themselves, their spouses, mothers, and fathers and their views about the rules in their nuclear and families of origin. The study group consisted of 12 married individuals, including eight females and four males, who were aged between 23 and 49, were not married to another participant, lived in the central county of a province in the central Anatolia region. The study used the phenomenological research design, which is one of the qualitative research approaches. The data were collected through semi-structured interviews, one of the qualitative research techniques, and analyzed with the content analysis method. The results of the study indicated that altruism and submissiveness were the common and prominent descriptions of the female participants about themselves and the descriptions of all participants about their mothers, whereas cold and distant were common descriptions of the participants about their mothers and fathers. It was found that the rules about couple relationships, family relationships, parenting, and spirituality/values were similar in nuclear and families of origin but that although the rules of the relationships with the family of origin/relatives and budget management were expressed in nuclear families, they were not expressed in families of origin
scMAGS: Marker gene selection from scRNA-seq data for spatial transcriptomics studies
No full textSingle-Cell RNA sequencing (scRNA-seq) has provided unprecedented opportunities for exploring gene expres-sion and thus uncovering regulatory relationships between genes at the single-cell level. However, scRNA-seq relies on isolating cells from tissues. Therefore, the spatial context of the regulatory processes is lost. A recent technological innovation, spatial transcriptomics, allows for the measurement of gene expression while preser-ving spatial information. An initial step in the spatial transcriptomic analysis is to identify the cell type, which requires a careful selection of cell-specific marker genes. For this purpose, currently, scRNA-seq data is used to select a limited number of marker genes from among all genes that distinguish cell types from each other. This study proposes scMAGS (single-cell MArker Gene Selection), a novel method for marker gene selection from scRNA-seq data for spatial transcriptomics studies. scMAGS uses a filtering step in which the candidate genes are identified before the marker gene selection step. For the selection of marker genes, cluster validity indices, the Silhouette index, or the Calinski-Harabasz index (for large datasets) are utilized. Experimental results showed that, in comparison to the existing methods, scMAGS is scalable, fast, and accurate. Even for large datasets with millions of cells, scMAGS could find the required number of marker genes in a reasonable amount of time with fewer memory requirements. scMAGS is made freely available at https://github.com/doganlab/scmags and can be downloaded from the Python Package Directory (PyPI) software repository with the command pip install scmags.Scientific and Technological Research Council of Turkey (TUEBITAK) [120C152]This study was supported by The Scientific and Technological Research Council of Turkey (TUEBITAK) [120C152 to B.D.]
Examination of cardiac morphology and functions of athletes from different branshes and sedentary participants
No full textAmaç: Bu araştırma, farklı branşlardan sporcular ile sedanter bireyler arasındaki morfolojik ve fonksiyonel farklılıkları belirlemeyi amaçlamaktadır. Materyal ve Metot: Araştırmaya aktif olarak antrenman yapan 32 yüzme, 28 sprinter atletizm sporcusu ve devamlı spor yapmayan 30 sedanter olmak üzere 90 katılımcı dahil edildi. Katılımcıların antropometrik ölçümleri yapıldı ve VO2maks değerleri için YoYo-1 IR1 performans testi, kardiyolojik ölçümler için EKO, EKG ve Holter testleri uygulandı. Çalışmanın istatiksel analizleri için Shapiro-Wilk, tek yönlü ANOVA ve Bonferroni çoklu karşılaştırma testleri kullanıldı. Bulgular: Araştırmada sedanter, yüzme ve sprinter atletizm grubunda yer alan katılımcıların ölçüm ve testler sonunda antropometrik değerlerinde VYO (p=.032), DKB (p=.004); Dayanıklılık performans değerlerinde Yo-Yo IR1 HR (p=.012), Mesafe (p=.000), VO2maks (p=.000); Kardiyolojik EKO değerlerinde IVSd (p=.003), LVPWd (p=.001), IVSs (p=.002), LVPWs ( p=.000), LVdmass (p=.000), LVsmass (p=.000), LVdmass ASE (p=.000), LVsmass ASE (p=.000); EKO ölçümlerinin VYA' da LVSd m2 (p=.012), LVPWd m2 (p=.004), IVSs m2 (p=.016), LVPWs m2 (p=.014); EKG ve HM değerlerinde SDNN Total (p=.030), SDNN Day (p=.014), RMS-SD Total (p=.008), RMS-SD Day (p=.002), SDSD Total (p=.027), SDSD Day (p=0003), HRV İndex (p=.006), TINN (p=.006), Mean RR Total (p=.000), Mean RR Day (p=.000), Mean RR Night (p=.014), Mean RR Delta (p=.027), Mean HR Total (p=.000), Mean HR Day (p=.000), Mean HR Delta (p=.012), pNN50 Total (p=.001), pNN50 Day (p=.000), SDNN İndex Total (p=.001), SDNN İndex Day (p=.000), Heart Rate Max (p=.000),Heart Rate Min (p=.005) ve Heart Rate Mean (p=.000) istatiksel olarak anlamlı farklılık tespit edilmiştir. Sonuç: Araştırma neticesinde elde edilen bulgulara göre; düzeli olarak antrenman yapan yüzücülerin kalp morfoloji ve fonksiyonlarının antrenman yapan atletizmciler ve sedander paydaşlarına göre daha farklı bulgulara sahip olduğu görüldü. Anahtar Kelimeler: Ekokardiyografi, Elektrokardiyografi, Sedanter, YüzmeAim: This research aims to determine the morphological and functional differences between athletes from different branshes and sedentary individuals. Materyal and Method: A total of 90 participants, including 32 swimming, 28 sprinter and track and field athletes, who were actively training, and 30 sedentary, who did not do sports regularly, were included in the study. Anthropometric measurements of the participants were performed and YoYo-1 IR1 performance test was performed for VO2max values, ECO, EKG and Holter tests were applied for cardiological measurements. Shapiro-Wilk, one-way ANOVA and Bonferroni multiple comparison tests were used for statistical analysis of the study. Results: In the study, the anthropometric values of the participants in the sedentary, swimming and sprinter athletic groups were found to be VYO (p=.032), DKB (p=.004); In endurance performance values, Yo-Yo IR1 HR (p=.012), Distance (p=.000), VO2 max (p=.000); IVSd (p=.003), LVPWd (p=.001), IVSs (p=.002), LVPWs (p=.000), LVdmass (p=.000), LVsmass (p=.000), LVdmass ASE (p=.000), LVsmass ASE (p=.000); In VYA, the EKO measurements were LVSd m2 (p=.012), LVPWd m2 (p=.004), IVSs m2 (p=.016), LVPWs m2 (p=.014); EKG and HM values of SDNN Total (p=.030), SDNN Day (p=.014), RMS-SD Total (p=.008), RMS-SD Day (p=.002), SDSD Total (p=.027), SDSD Day (p=0003), HRV Index (p=.006), TINN (p=.000p RR Mean=.000p RR). 014), Mean RR Delta (p=.027), Mean HR Total (p=.000), Mean HR Day (p=.000), Mean HR Delta (p=.012), pNN50 Total (p=.001), pNN50 Day (p=.000), SDNN Index Total (p=.001), SDNN Index Index Day (p=.000), Heart Rate (p=.000), Heart Rate (statistically significant difference was detected). Conclusion: According to the findings obtained from the research, it was observed that swimmers who regularly train have different cardiac morphology and functions compared to athletes who train regularly and sedentary participants. Keywords: Echocardiography, Electrocardiography, Sedentary, Swimmin
A Novel Current Condition Assessment System for Sustainable Management and Operation of Wastewater Treatment Plants
No full textWastewater treatment is important in terms of human and environmental health in the urban water management cycle. Appropriate methods should be applied based on accurate data in order to ensure efficiency. This study developed a novel current condition assessment system to evaluate the data quality and the implementation level of wastewater treatment plant (WWTP) management and operations practices. The developed system consists of 48 components including the basic processes used in the operation of WWTPs. A unique scoring system is proposed to evaluate the system. The developed system was tested in three pilot WWTPs. The performance of Utility 2 was better than that of the other utilities in terms of data quality and implementation level of methods. However, the scores of Utilities 1 and 2 generally were close to each other. The weaknesses and strengths were determined within the scope of WWTP management in each utility