Kurdistan Journal of Applied Research (KJAR)
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Seroprevalence of HCMV among Pregnant Women and Its relation to CD4 and CRP
Get PDFThe HCMV is a widespread viral pathogen characterized by strict host specificity and is limited to humans. It has been described as an important etiological agent of intrauterine infection in during the pregnancy, which may lead to some serious results such as miscarriage, cerebellar malformation stillbirth, and fetus developmental retardation. The study carried out in Kirkuk governorate from the December 2017 to May 2018 for study the relation of CD4 percentage and CRP with HCMV seropositive pregnant women. The number of pregnant women under study was two hundred women attending to some private medical laboratories in Kirkuk. The pregnant women were examined for the seroprevalence of HCMV IgM and IgG antibodies by using VIDAS technique. The results were (81 %), (9%) and (6%) for HCMV-IgG, HCMV-IgM and for both IgG & IgM at the same time respectively. The highest rates (41.66%) of decreased CD4 percentage were within seropositive pregnant women for both IgG & IgM at same time, while the highest rates (16.66%)of CRP positive were found within HCMV-IgM seropositive group
Effect of Tick and Lice on Some Blood Constitute and Trace elements of Local Black Goat in Sulaimani, Kurdistan Region of Iraq
Get PDFIn this study isolated 100 adult female of local black goat (Capra hircus) examined in spring and fall season for Tick and Lice investigations, then divided into two groups: 50 infested goats with ectoparasite and 50 non-infested goats. Three species of ticks (Rhipicephalus sanguinus, R. turanicus and R. bursa) and one species of lice (Bovicola caprae) were observed. Biochemical values (serum proteins and some trace elements) analyzed, in infested goats emerges decline in serum protein value 7.12±0.08 µg/dl, albumin value 4.12±0.03 µg/dl and increase of globulin value 3.04±0.09 µg/dl, in serum protein and globulin values shows not significance differences, while described highly significance differences in albumin value at p?0.01, when compared to control goats. In trace elements decline of zinc level 48.97±1.20 µg/dl and copper level 114.15±3.75 µg/dl levels with a highly significant differences at p?0.01 in infested goats when compare to control goats. It is observed that mixed infestation has much effects than tick or lice infestation on goats, which led to reduction in serum protein value 6.89±0.20 µg/dl, albumin value 4.11±0.09 µg/dl and raise in globulin value 3.10±0.11 µg/dl without any significance differences, also noticed insignificant declines in zinc level 45.67±2.40 µg/dl, while decrease in copper level 99.33±9.86 µg/dl significantly at p?0.05
Impact of Diabetes Mellitus Type 2 in the Activity of Glucose-6-Phosphate Dehydrogenase in Human Erythrocyte
Get PDFDiabetes mellitus is a metabolic affliction saunter that is characterized by a nobler than normal blood glucose poise. Glucose-6-phosphate dehydrogenase (G6PD) enzyme code (E.C.1.1.1.49) is an underlying enzyme in the phosphogluconate pathway. In this study, G6PD vitality in the mortal erythrocyte of male and female patients with type 2 diabetes mellitus was assessed utilizing a spectrophotometer at 340 nm. The activity of the enzyme increased with elevated glycated hemoglobin (HbA1C) levels. G6PD activity was found to be significantly associated with type 2 diabetes mellitus. The association between G6PD and diabetes mellitus was significant (P < 0.001). Moreover, G6PD was positively correlated with HbA1C levels (r = 0.572). The following mean ± standard deviation values were obtained: G6PD activity (IU/g Hb), 3.1103 ± 0.79349; HbA1C (%), 8.6600 ± 1.63120; Hb (g/dL), 13.4933 ± 1.38836; platelet count (103/µl), 283.4667 ± 58.59312; WBC (103/µl), 7.4890 ± 1.49842; HCT (%), 45.0100 ± 2.63430; and BS (mg/dL), 230.2667 ± 75.67760. The results showed that an elevated HbA1C up leads to increased G6PD performance in the human erythrocyte, which is concerning to glucose levels in the special (blood)
Dyslipidemia among Patients with End Stage Renal Disease on Maintenance Hemodialysis
Get PDFDyslipidemia has been suggested to be one of the factors that contribute to the high incidence of cardiovascular disease in hemodialysis patients. Previous studies suggest that end-stage renal disease may contribute to dyslipidemia. The aim of the study: to assess the prevalence of dyslipidemia in patients on maintenance hemodialysis. Patients and Methods: A case-control study was conducted from February 2015 until August 2015 in Ibn-Sena teaching hospital on 100 participants (52 males and 48 females), 50 were patients with end-stage renal disease on regular hemodialysis and 50 were age and gender-matched apparently healthy subjects as the control. Questioner used to collect data, a thorough examination was done including height and weight and BMI. A blood sample from all participants in fasting state was sent for the renal function test, complete blood picture, serum albumin, electrolytes, TG, total cholesterol, LDL and HDL measured by the enzymatic method, plasma atherogenic index calculated as [log (TG/HDL)]. Results: Age of the participants ranged between 18 - 70 years and the mean age was (44.45 ± 13.6) years. In HD group, the mean cholesterol was (3.29 + 0.73) mmol/l, serum TG (2.38 ± 0.56) mmol/l, LDL (1.91 ± 0.66) mmol/l, HDL (0.88 ± 0.2) mmol/l, atherogenic index (0.434 ± 0.16), while in control group, the mean cholesterol was (4.17 ± 0.69) mmol/l, serum TG (1.6 ± 0.43) mmol/l, LDL (2.69 ± 0.63 ) mmol/l, HDL (1.066 ± 0.13) mmol/l, atherogenic index (0.177 ± 0.12). The lipid abnormalities in hemodialysis group were high plasma atherogenic index in 84%, hypertriglyceridemia 50%, hypercholesterolemia 8% and high LDL 6% and low HDL in 48%, while in control group, high plasma atherogenic index in 34%, hypertriglyceridemia in 26%, hypercholesterolemia 14% high LDL 7% and low HDL in 16%. Conclusions: patients with end-stage renal disease on hemodialysis have significant dyslipidemia compared to control group characterized by hypertriglyceridemia, low HDL and high atherogenic index of plasma
Cardiovascular Risk Assessment among Adults in Primary Health Care Settings in Sulaimani Using WHO Risk Prediction Charts
Get PDFWHO adopted World Health Organization/International Society of Hypertension (WHO/ISH) risk charts to predict cardiovascular disease risk in low and middle income countries. The aim of this study was to estimate the cardiovascular risk in adults ?40 years old by using the two versions of the WHO/ISH risk prediction charts “with and without cholesterol”, and to find out the risk by other parameters not found in the chart; also, to evaluate concordance between the two approaches. A cross-sectional study was conducted from August 2016 to February 2017 in two primary health care centers in Sulaimani City among 500 persons aged 40-82 years. The desired information was collected by using a pretested questionnaire; anthropometric measurements and laboratory investigations were also carried out for the participants. Cardiovascular risk was assessed by the WHO/ISH risk prediction charts for the Eastern Mediterranean region in category D. Mean age of the participants was 52.5(±9.55) years and 70.4% of the participants were females. Only 260 participants had the results of total cholesterol and triglycerides. The results revealed that, using the risk assessment charts with and without cholesterol, 22.3% and 19.2% respectively of the study population were in the ten-year cardiovascular risk category of ?20%. Risk categories were concordant in 86.2% of the population; and when we applied single risk factor approach 51.5% would require drug treatment. The WHO/ISH risk chart is an affordable and simple tool to estimate cardiovascular disease risk. Nearly one fifth of adults aged ? 40 years in Sulaimani City are at high-very high risk of developing cardiovascular event in the next ten years as assessed by WHO/ISH risk prediction charts. The use of the without cholesterol version of the chart to estimate cardiovascular disease risk could be useful is settings where cholesterol cannot be measured
Nurses’ Knowledge Regarding Cardiac Catheterization at General Hospital in Rania City
Get PDFCardiac catheterization is a common word for a set of procedures that are implemented using this method, such as coronary angiography and left ventricle angiography. Coronary angiography is that invasive procedure which assumed as the golden standard for the diagnosis, estimation, and curing of heart diseases. There is a shortage of research of undergraduate students. The purpose of this descriptive cross-sectional study has been conducted to assess nurses’ knowledge regarding cardiac catheterization and associated factors at General Hospital in Rania city. Data were collected from a stability sample of 60 nurses using demographic form instead of the section with the conductive questionnaire of Knowledge regarding cardiac catheterization . The majority of study participants were female (81.7%) Therefore, 70% of nurses were married. About 43.3% of study participants were Academic nurse while (40%) of them were Institute nurse, however level of knowledge form institute graduated nurses has a highest level and the majority of participants were not trained (95%). Results acquired have shown that there is no sufficient knowledge of nurses regarding cardiac catheterization, among all levels of nurses and there is a significant relationship between most socio-demographic data in true question but there are opposite result for false questions. We therefore recommend the training course by ministry of health for nurses to improve the knowledge and health awareness regarding cardiac catheterization
The Impact of Teaching Materials on Learning Computer Programming Languages in Kurdistan Region Universities and Institutes
Get PDFIt is evident that learning and teaching computer programming are considered as one of the striking challenges in academic environments. Meanwhile, selecting the correct and appropriate materials can leave an enormous impact in learning computer programming languages. However, recently this argument has been put under scrutiny as to which types of materials motivate learners to learn computer programming languages as well as enhance learning outcomes. Therefore, the main objective of this study is to investigate the current teaching and learning materials of computer programming languages in Kurdistan region of Iraq universities. Additionally, another aim is to give a rigorous analysis of how materials help students to learn computer programming language. A further focus is to identify the difficulties of learning computer programming languages at undergraduate level which constitutes technical Diploma and Bachelor. The last but not the least, this paper examines new approaches to teaching programming languages as a cognitive model for programming education
Epidemiological Characteristics and Family Relatives among Thalassemic Patients in Sulaimani City, Kurdistan Region, Iraq
Get PDFThalassemia is a well-known inherited hematologic disorder caused by a decrease or an absence of globin production. Patients with thalassemia suffer from chronic hemolytic anemia and its sequelae. A descriptive study was undertaken in Sulaimani Thalassemia and Congenital Blood Disease Center. The self-administered questionnaire was used to 140 patients who had thalassemia and visited to the hospital during the study periods to assess the patients’ characteristics and parent’s relative’s relation to thalassemic patients. Data were entered into spreadsheets and analyzed in Statistical Package for Social Sciences (SPSS) version 22. Descriptive analysis was performed and frequencies and percentages were reported. Associations between categorical variables were checked using Chi-squared test. Out of 140 patients 50.0% of patients were males and 50.0% were female; the mean age was 12.8 years-old. The most frequent thalassemic patents were come from rural area 95.0%. Majority of patients have major type of thalassemia 84.3%. Most of the patients cannot continue to the study accounted 66.4%. About number of children most of the patient’s family had more than 3 children 99.3%. Majority of patient’s parents is carrier for thalassemia and accounted with 90 (65.0%), from those patients with major thalassemia are 77 (85.6) and few cases with minor thalassemia 4 (4.4%). These relations are statistically significant at (p<0.05). Majority of patients who have major type of thalassemia were from rural area followed by urban area 113 (95.8%) vs. 7 (5.0%), these differences are statistically significant at (p?0.01), from major types of thalassemic patients; 85 (94.4%) of them were both father and mother are carrier of thalassemia. Statistically significant relation was found at (p<0.05). In conclusion, thalassemia is an important cause of morbidity among thalassemic patients. In our community, thalassemia is more frequent in rural population. Therefore, it is a crucial for monitoring and examination of those who are carriers. Moreover, the lack of health education on thalassemia was the major problems related with awareness of families. 
Treating Antibiotic Resistance Genes in Proteus Spp. were Isolated from Renal Stone Patients by Crataegus rhipidophylla and Adiantum capillus
No full textNine isolates of Proteus spp. were isolated from 100 urine samples of renal stone patients which were the urine specimens obtained directly from Sulaimani Teaching Hospital Laboratory, and identified according to the cultural characteristic, morphological, biochemical examination. The antibiotic susceptibility test for all isolates were conducted to nine antimicrobial agents including (Ciprofloxacin (Cip), Tetracycline(TE), Neomycin (N), Gentamicin (CN), Erythromycin (E), Nitrofurantoin (F), Naldixic acid (NA), Imipenem (IPM), Amoxicillin (AX). Plasmid analysis of these isolates showed presence are (22) Kb plasmid. Curing of antibiotic resistance genes by using methanol extracts for leave of Crataegus rhipidophylla and Adiantum capillus was performed. The minimum inhibitory concentration of these medicinal plants through methanol extracts which were 5000 µg/ml and 1000 µg/ml for Ailanthus altissima and Adiantum capillus respectively. The Sub minimum inhibition concentration (SMIC) was also determined. The results of transformation and curing experiments revealed that SMIC of Ailanthus altissima extract was cured or eliminated plasmid completely, and (SMIC) of Adiantum capillus was cured (CN, E, and AX) resistant genes
Complement protein and Immunoglobulins Serum levels in Normal Pregnant and Spontaneous Aborted Women
Get PDFDisorder of maternal immune responses during pregnancy triggers immunological rejection of fetus antigens by maternal immune components, contribute to spontaneous abortion or miscarriage. The study was designed to concentrated on immunoglobulins (IgM, IgG and IgA) and complement elements (C3 and C4) serum levels changes in normal pregnant and abortion women. Study groups were classified into normal pregnant women (20), spontaneous abortion (30) and non-pregnant women (16) as a control group, attending to Shahid Dr. Khalid Hospital/Department of Gynecology and Obstetrics/Koya city. Serum levels of immunoglobulins (IgG, IgM, and IgA), complement proteins (C3 and C4) were determined and analyzed for normal pregnant, abortion and control groups by using Single Radial Immunodiffusion (SRID) technique. The results demonstrated that concentration of IgG levels in abortion differed significantly in compare to normal pregnancy (p ?0.05), while there were no significant differences in IgM and IgA serum levels among groups (p >0.05). Also, statistical analysis revealed that serum levels of C3 and C4 significantly decreased in abortion group compared to normal pregnant and non-pregnant groups (p ?0.05). Concluded that complement proteins (C3 andC4) are a good defense line during normal pregnancy, sometime activation (hyper-consuming) of complement elements may provoke spontaneous abortion, while immunoglobulins are a little role in inducing of miscarriage in pregnant women.