Journal of Widya Medika Junior
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THE EFFECT OF ETHANOL EXTRACT FROM STROBILANTHES CRISPUS AGAINST C-REACTIVE PROTEIN IN DIABETIC RATTUS NORVEGICUS
Get PDFBackground : Diabetes Mellitus is a metabolic syndrome that causes various complications in the body due to various mechanisms of increased ROS and increased pro-inflammatory cytokines in the body such as IL-6, IL-1β, and TNF-α. The increase in numbers of pro-inflammatory cytokines and inflammation in the body can cause the formation of CRP which plays a role in the phagocytosis process and also increases the secretion of pro-inflammatory cytokines.Objective : The purpose of this research was to determine whether the administration of Keji beling’s leaves extract had an effect on CRP levels in diabetic rats.Method : This research used male Rattus novergicus wistar strain induced with diabetes using alloxan. The rats in the control group were given 0.5% Na CMC, ethanol extract of Keji beling’s leaves at a dose of 100 mg (P1), 400 mg (P2), and 600 mg/kg (P3) for 24 days and then the rat’s blood serum was examined for CRP using the CRP method which is Quantitative latex agglutination immunoassay using Nanopia CRP. Results : There were no significant difference in CRP levels between each group. The lowest levels of CRP were found in the extract group with a dose of 400 mg/kg (0.1± 0.0 mg/L), 600 mg/kg (0.12 ± 0.0447 mg/L) and the highest at 100 mg/kg (0.2 ± 0.2236 mg/L). Administration of a dose of 600 mg/kg had a significant effect on lowering blood glucose on diabetic rats (p = 0.047), giving a dose of 400 mg/kg also had an effect in lowering blood glucose but still not significant. The group which were given a dose of 100 mg/kg did not have an effect on lowering blood glucose.Conclusion : There were no effect on the administration of ethanol extract from Keji beling’s leaves on CRP levels in diabetic rats. Keywords : Keji beling, diabetes mellitus, CRP, antioxidants, blood glucose
DIPHOTERINE: A RECOMMENDED OCULAR IRRIGANT FOR CHEMICAL EYE INJURY
Get PDFChemical eye injuries are medical emergencies that require prompt and effective treatment in order to avoid permanent vision loss. The initial and most critical step in managing such injuries is the immediate irrigation of the afflicted eye to dilute and eliminate the harmful chemical, resulting in better outcomes. Various ocular irrigants are used for this purpose, each with its advantages and limitations. Diphoterine is an amphoteric solution that is most efficient, providing both comfort for patients and effectiveness in term of volume needed and overall effectiveness as an ocular irrigant
THE EFFECT OF REHABILITATION USING THE SCHROTH METHOD ON REDUCING THE DEGREE OF SCOLIOSIS IN ADOLESCENTS AGE 13-17 YEARS AT POSTURE CLINIC SURABAYA
Get PDFBackground : Scoliosis is one of the most common spinal deformities that occurs in Indonesia, although spinal deformities doesn’t get much attention. This lack of attention causes the prevalence of scoliosis keeps on increasing and most people will seek intervention after several symptoms and discomforts start to appear in day to day activities. The easiest examinations that can help to diagnose scoliosis is with Adam’s Forward Bending Test and Scoliometer is used to determine one’s scoliosis degree. A certain rehabilitation that people with scoliosis especially with degree’s that ranges between 5°-7° is a Schroth method rehabilitation.
Objective : This study aims to determine the effect of Schroth method rehabilitation on reducing the degree of scoliosis in adolescents age 13-17 years in Posture Clinic Surabaya.
Method : This study is an observational analytical study with a reetrospective cross-sectional design using secondary data from the medical records. The medical records contains of pre- and pots- rehabilitation of patients using Schroth method in Posture Clinic Surabaya. There are 24 samples in this.
Results : This research showed a significant effect in rehabilitation usinf the Scrhoth method on reducing the degree of scoliosis.
Conclusion : There is a significant effect of rehabilitation using the Schroth method on reducing the degree of scoliosis in adolescents age 13-17 years at Posture Clinic Surabaya
THE RELATIONSHIP BETWEEN SMOKING HABITS AND THE INCIDENCE OF CHRONIC URTICARIA IN CIVITAS WIDYA MANDALA CATHOLIC UNIVERSITY SURABAYA
Get PDFBackground: Urticaria is a heterogeneous disease with multiple causative factors. A thorough literature research has revealed a very limited amount of evidence about the effects of smoking and alcohol consumption habits on the clinical characteristics of urticaria.. Atopic allergic which mean urticaria can affect all populations, but is most common in those aged between 20 to >60 years. Smoking has been reported to play a role in the onset of Urticaria. Substances in cigarette smoke can interact with body cells, resulting in the formation of free radicals or Reactive Oxygen Species (ROS).Objective: To see the relationship between smoking habit and the incidence of chronic urticaria among civitas at Widya Mandala Surabaya.Methods: The method used in this study was a case-control study by taking a population of civitas at the Widya Mandala Surabaya who had smoking history from 2020 to 2023. A sample of 94 people was obtained who had met the inclusion and exclusion criteria of the study. The sample of this study was divided into two groups consisting of a case group and a control group.Results: The results of the Contigency Coefficient Correlation test showed a significant p value of 0.031 <0.05, which means that there is an important correlation between smoking and the incidence of chronic urticaria among civitas at the Widya Mandala Surabaya.Conclusion: It is proven that there is a relationship between smoking and the incidence of chronic urticaria in civitas of Widya Mandala Surabaya
RELATIONSHIP BLOOD TRIGLYCERIDE LEVELS WITH ACNE VULGARIS IN YOUNG ADULTS
No full textIntroduction: Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous follicles. The four main pathologies underlying the occurrence of acne vulgaris are follicular epidermal hyperproliferation, increased sebum production, colonization of Propionibacterium acnes and inflammatory processes. Triglycerides are a component of sebum which plays an important role in the inflammatory process.Objective: to determine the relationship between triglyceride levels in the blood and acne vulgaris in young adults.Method : this research is analytic. The research design used was cross sectional. The population of this study were all patients who came to the clinic. The sample in this study used an accidental sampling technique.Results: The study showed that the characteristics of the respondents based on the Chi-Square test for the relationship between triglyceride levels and the incidence of Acne vulgaris showed that there was a statistically significant relationship between triglyceride levels and the incidence of Acne vulgaris.Conclusion: There is a relationship between triglyceride levels in the blood and the incidence of acne vulgaris in young adults
THE CORELATION OF THE QUALITY OF ANTENATAL CARE VISITS WITH THE INCIDENT OF ASPHYXIA NEONATORUM AT PHC HOSPITAL SURABAYA
Get PDFBackground: Birth asphyxia is the one of the very common problem in neonatal health care. Its incidence is very high in the developing country where health facilities are restricted to urban area, and these factors can be prevented through standard Antenatal Care (ANC) visits. ANC is medical care provided by healthcare professionals to mothers during pregnancy, administered by medical personnel and conducted according to established standards. This ANC monitors the health and development of both the mother and the fetus for early detection of risks and health issues during pregnancy.Objective: To determine the relationship between the quality of ANC visits and the occurrence of Asphyxia Neonatorum at PHC Hospital Surabaya.Method: This research is an observational analytic study with a case-control study design, employing a retrospective approach. The sampling in the study utilized probability sampling, specifically employing the simple random sampling technique. The statistical method used to examine the relationship between the quality of ANC visits and Asphyxia (APGAR Score ≤3-6) through the analysis of odds ratio comparison using the Chi-square statistical test.Result: The statistical analysis of the relationship between the quality of ANC visits and the occurrence of Asphyxia shows significant results with a p-value of 0.001 (p < 0.05).Conclusion: The compliance of pregnant women in adhering to standard ANC visits ensures the health of both the mother and the baby during pregnancy
THE EFFECT OF SUBMAXIMAL EXERCISE ON THE ATTENTION OF HEALTHY ADULTS
Get PDFIntroduction. Submaximal exercise uses intensity below 85% of the predicted maximum pulse for age. One example of a submaximal exercise is the Three-minutes step test (TMST) which is practical, easy to implement in the subject's routine, and has clear measurement standards. After TMST is done, VO2max can be calculated which is the main indicator used to determine cardiorespiratory capacity. There have been no studies evaluating the effect of submaximal exercise and VO2max on domain attention in healthy adults.Aim. This study aim to evaluate effect submaximal exercise on the attention of healty adults.Material and method. Using a controlled before-and-after study, sixty healthy adults, aged 25-40 years, were divided into control and intervention groups (TMST). Attention function was measured with SDMT (Symbol Digit Modalities Test) before and after TMST or 3 minutes rest.Result. There was a significant difference in the intervention and control groups (p values <0.001 and 0.0029). The values of SDMT in the intervention group with the control group were significant with the p-value is <0.0001. The effect of the TMST intervention on SDMT was significant, with p values <0.0001.Conclusion. Submaximal exercise can improve attention function in healthy adults
CLINICAL PROFILE OF STROKE PATIENTS IN GOTONG ROYONG HOSPITAL
Get PDFBackground: Stroke is a global health issue due to its high prevalence, mortality, and associated disabilities. The Global Burden of Disease Study identifies ischemic and hemorrhagic strokes as significant contributors to global health burdens. Understanding these factors in different populations is crucial for developing targeted interventions and improving patient outcomes.Methods: This retrospective descriptive study analyzed medical records of stroke patients at Gotong Royong Hospital from January to December 2023. Patients aged 18 years or older with acute stroke confirmed by CT or MRI were included.Results: Out of 224 stroke patients, 58% were male and 42% female. Most patients were over 70 years old (31.7%), with 29% aged 51-60 and 26.3% aged 61-70. Ischemic stroke was predominant (91.5%), while 8.5% had hemorrhagic stroke. Many patients (40.2%) arrived at the emergency department more than 24 hours after symptom onset. Hypertension was present in 68.8% of patients, diabetes in 36.6%, and dyslipidemia in 24.1%. The average length of stay was 4.13 days. Blood pressure measurements showed high prevalence of Grade 2 hypertension in systolic (37.05%) and prehypertension in diastolic (30.80%). Laboratory results revealed mean random blood glucose of 174.3 mg/dL, fasting blood glucose of 110.42 mg/dL, HbA1C of 8.06%, LDL cholesterol of 120.31 mg/dL, and triglycerides of 151.26 mg/dL.Conclusion: The majority of acute stroke patients at Gotong Royong Hospital are male, over 60, with ischemic stroke, and present more than 24 hours post-onset. These patients typically have a history of hypertension but no previous strokes, with an average hospital stay of 4 days. Many exhibit Grade 2 hypertension in systolic blood pressure and prehypertension in diastolic pressure. Understanding these profiles can guide better management and preventive strategies for stroke patients
CORRELATION OF ACADEMIC STRESS WITH OLIGOMENORRHEA IN FEMALE MEDICAL STUDENTS
Get PDFIntroduction: Oligomenorrhea is defined as an irregular menstrual cycle of more than 35 days or only experiencing 4 to 9 menstrual cycles in a year. According to research involving 12,964 women of childbearing age in China, it was found that 1,579 women (12.2%) experienced oligomenorrhea. Risk factors for oligomenorrhea are poor nutritional status, namely BMI < 18.5 or ≥ 25, excessive physical activity, high levels of stress (around 20%), and late age at menarche. Various studies have found a relationship between stress and abnormal menstrual cycles.Objective: To determine the relationship between academic stress and oligomenorrhea infemale students at the Faculty of Medicine, Widya Mandala Catholic University, Surabaya, Class of 2019.Method: Analytical observational research with a cross-sectional approach. The population for this research is all 7th-semester female students at the Faculty of Medicine, Widya Mandala Catholic University, Surabaya, class of 2019, with a total sample of 32 female students taken using simple random sampling. The independent variable is academic stress while the dependent variable is oligomenorrhea. The research instrument used a questionnaire. Data analysis used the Spearman Rank correlation test.Result: A total of 20 respondents (62.5%) experienced moderate levels of academic stress, 3 respondents (9.4%) experienced low levels of academic stress, and 9 respondents (28.1%) experienced high levels of academic stress. For the menstrual cycle from August to October 2022, 23 female students (71.9%) experienced normal menstrual cycles, and 9 female students (28.1%) experienced oligomenorrhea. The results of the Spearman Rank correlation test obtained a significance value of 0.023.Conclusion: There is a relationship between academic stress and oligomenorrhea in students at the Faculty of Medicine, Widya Mandala Catholic University, Surabaya, Class of 2019
A RARE CASE OF CERVICAL LEIOMYOSARCOMA: CASE REPORT AND COMPREHENSIVE MANAGEMENT AT PHC SURABAYA HOSPITAL
Get PDFIntroduction: Cervical cancer is a malignant neoplasm that grows from cells originating from the cervix in the uterus. Leiomyosarcoma is a type of neck cancer that is relatively rare, data from the USA shows an incidence rate of only 0.35-0.64 per 100,000 women.Objective: This paper reports on the management of leiomyosarcoma cases at PHC Surabaya Hospital.Case Report: A 45-year-old female patient complained of continuous menstruation. An ultrasound was performed, and a biopsy was planned due to the mass found during the ultrasound. The biopsy showed cervical malignancy. A total hysterectomy, and bilateral oophorectomy, were performed and a PA examination was carried out on the uterine samples resulting from the operation the results, were leiomyosarcoma, high-grade, cervix, invasion in the stroma of the parametrium, vaginal cuff and both sides of the lymph nodes were free of tumor (pt1b3 n0mx)Conclusion: The patient was treated for 3 days at PHC Hospital after surgery and went home without complications from the surgical wound. The patient returned to control after 6 months with signs of tumor recurrence and negative metastases