Journal of Widya Medika Junior
Not a member yet
264 research outputs found
Sort by
Correlation Of Body Mass Index With Prostate Volume In Benign Prostatic Hyperplasia Patients
Get PDFIntroduction: Benign prostatic hyperplasia (BPH) is the most common prostatic disease inmen. Multiple factors influence the pathogenesis of BPH, and one of them is obesity. Variousstudies about the correlation between obesity and prostate volume show inconsistent results.Some studies reported that obesity correlates with prostate volume, whereas others didn't findthe correlation between obesity and prostate volume. Therefore, this study aims to find thecorrelation between obesity and prostate volume. Purpose: To find the relationship between body mass index (BMI) and BPH patients'prostate volume. Methods: BMI was measured by BMI formula, and prostate volume was measured bytransabdominal ultrasound (TAUS). This study was conducted in RSUD Ibnu SinaKabupaten Gresik by looking at medical records in January 2016-September 2017. This studywas an analytical observational study with a cross-sectional approach. This study uses LinearRegression Test to analyze the correlation of in-between variables. This study's populationwas patients with a diagnosis of BPH that undergo hospitalization in RSUD Ibnu Sina (273medical records). The study sample that corresponding to inclusion and exclusion criteria are27 medical records. Result: The average prostate volume in underweight criteria was 44,5 cm3, in normal criteriais 42,4 cm3. Highest average of prostate volume found in overweight criteria, which was 64,3cm3. In the obese criteria, the average prostate volume was 32,2 cm3. The average prostatevolume was 46,0 cm3. From the linear regression test, we found the value of p=0,881 andR2=0,01. Conclusion: There is no significant correlation between BMI and prostate volume in thisstud
EPIGENETIC STUDY AS A NEW APPROACH FOR THERAPEUTICS AND BIOMARKER OF ATHEROSCLEROSIS IN COVID-19
Get PDFIntroduction : Coronavirus disease 2019 (COVID-19) has affected more than 105 million people globally and resulted in at least 2.3 million deaths. Covid-19 has highlighted the vulnerability of aging populations to emerging diseases. This susceptibility to disease and death is also a major challenge for the development of vaccines and immunotherapeutic agents. Atherosclerosis is one of the main cardiovascular disease, and this disease is one of the most common comorbid diseases affected by Covid-19 and is associated with increased risk of mortality. Biomarker are crucial in decision-making in order to facilitate efficient resource allocation. Recently many researcher develop several biomarker as a new approach in epigenetic area. The discovery of new therapeutic targets as well as biomarkers using epigenetic studies may increase its clinical usefulness. Methods: In this narrative review, a search was carried out with the help of several search engines that match the criteria, namely "Epigenetic Studies Based On Cardiovascular Disease Especially In Atherosclerosis".Results: One paper was obtained that supports and fits the criteria, namely the role of miRNA in the formation of atherosclerotic plaques.Conclusion: miR-486-5p can be used as a new therapeutic target and biomarker in atherosclerosis patients, but this requires further researc
CORRELATION BETWEEN EXCLUSIVE BREASTFEEDING IN GROUP OF EARLY INITIATION OF BREASTFEEDING ON THE DURATION OF LACTATIONAL AMENORRHEA
Get PDFIntroduction: Based on data from "Survei Demografi dan Kesehatan Indonesia" (SDKI) in2012, about four percent of births occurred 18 months apart, and six percent were less thantwo years apart, about 75 percent occurred at least three years apart. WHO’s recommendation for birth spacing is at least 24 months. A gestation interval of fewer than six months can increase maternal mortality due to premature rupture of the amniotic sac, anemia, and puerperal endometritis. The Lactational Amenorrhea Method is a natural and easy method of contraception. The LAM method is one of the contraceptive methods with a success rate of 98 percent. One of the importance of contraception, such as LAM, is to adjust the optimal birth spacing. Purpose: This study aims to determine the correlation between exclusive breastfeeding in agroup of early initiation of breastfeeding on the duration of lactational amenorrhea. Method: This study is an observational analytic study with a retrospective cohort studydesign. A simple random sampling technique is used for the sampling method. The collectionof data on the history of breastfeeding and the duration of amenorrhea was collected from the main research results by doing interviews with respondents. Results: The results of statistical tests with Spearman correlation showed that the P-valueobtained is 0.005. This value is less than p (0.05), which means a significant correlationbetween exclusive breastfeeding and the duration of lactational amenorrhea. Conclusion: There is a significant correlation between exclusive breastfeeding in the earlyinitiation of the breastfeeding group and the duration of lactation amenorrhea
POLYMORPHISM OF INTERLEUKIN-10 (-819) GENE IS NOT ASSOCIATED WITH LIVER DAMAGE AMONG CHRONIC HEPATITIS B PATIENTS
Get PDFIntroduction: Chronic hepatitis B (CHB) is characterized by chronic liver inflammation andhepatocellular damage caused by hepatitis B virus (HBV), leading to fatal liver diseases such as cirrhosis and hepatocellular carcinoma (HCC). Liver damage causes elevated levels of serum alanine aminotransferase (ALT). Previous studies have shown that IL-10 gene polymorphism (-819 C/T) is linked to several diseases, including inflammatory, autoimmune diseases, and cancer. Purpose: To investigate the relationship between IL-10 gene polymorphisms (-819 C/T) and liver damages in chronic hepatitis B patients at Arifin Achmad Regional Hospital, RiauProvince.Method: This study was an analytical study with a cross-sectional approach. Liver damages were examined by measuring ALT levels, and IL-10 gene polymorphisms were analyzed using Amplification-Refractory Mutation System Polymerase Chain Reaction (ARMS-PCR). Results: There were 74 subjects included in this study, aged 45.47±13.42 years old,consisting of 43 males (58.1%) and 31 females (41.9%). Of 74 subjects, 35 CHB patientswere presented without complication, 26 CHB patients were complicated with cirrhosis, and 13 CHB patients were complicated with hepatoma. The genotype of the IL-10 (-819) gene polymorphism in this study was found as follows: CT genotype in 34 subjects (45.9%), TT genotype in 30 subjects (40.5%), and CC genotype in 10 subjects (13.5%). There was nosignificant relationship between IL-10 gene polymorphisms (- 819) and liver damage inchronic hepatitis B patients (p> 0.05).Conclusion: IL-10 gene polymorphism (-819) may not contribute to liver damages amongCHB patients
RELATIONSHIP BETWEEN SLEEP QUALITY AND COGNITIVE FUNCTION IN ELDERLY IN THE TRESNA WERDHA SOCIAL ASSISTANCE KHUSNUL KHOTIMAH PEKANBARU
Get PDFBased on data on population projections in Indonesia in 2015-2045, age groups of 60 and over will continue to increase. A large number of the elderly population can be a burden if the elderly have health problems. As we get older, there will be physical appearance, function and response in daily activity. The occurrence of sleep disorders will have an impact on cognition. To determine the correlation of sleep quality with cognitive function in the elderly in UPT PSTW Khusnul Khotimah Pekanbaru. This type of research is observational analytic with the cross-sectional approach. The study was conducted at UPT PSTW Khusnul Khotimah Pekanbaru. The sampling technique used was total sampling, with 46 respondents from a total population of 58 respondents in the UPT PSTW Khusnul Khotimah Pekanbaru. Researchconducted on 46 respondents found 67% of respondents with poor sleep quality and as manyas 65% of respondents experiencing cognitive impairment. Statistical test to determine therelationship of sleep quality with cognitive function in the elderly using the SpearmanCorrelation test showed that there was a significant relationship between sleep quality andcognitive function in the elderly in UPT PSTW Khusnul Khotimah Pekanbaru with a p-valueof 0.003 (<0.05) and coefficient correlation (r) 0.427 shows the strength of the moderaterelationship with the direction of the positive correlation. Sleep quality is related to andinfluences cognitive function in the elderly at UPT PSTW Khusnul Khotimah Pekanbaru.
DIFFERENCES OF MASS AND DIAMETER MUSCLE RATTUS NORVEGICUS IN GIVING KETOGENIC DIETS AND EXERCISE
Get PDFIntroduction: Saturated ketogenic diet without exercise can lead to muscle mass decrease and disturb body metabolism. Therefore, the researcher is interested in discovering the differences between a saturated and unsaturated ketogenic diet with exercise to muscle mass and diameter. Purpose: This study aimed to analyze the difference in muscle mass and diameter of Rattus norvegicus, which were given a ketogenic diet and exercise. Method: This experimental research used Rattus norvegicus that had been adapted for two weeks. Rats are divided into five groups; control (K), a saturated ketogenic diet (P1), a saturated ketogenic diet with exercise (P2), an unsaturated ketogenic diet (P3), and anunsaturated ketogenic diet with exercise (P4). Upright running wheel exercise was given to the group with exercise for 10 minutes daily. The ketogenic diet was given with oral gavage. Muscle mass was examined in the second and fourth weeks. Muscle diameter was examined before treatment, second week, and fourth week. Results: There are differences in mass and diameter muscle Rattus norvegicus that givenketogenic diet and exercise (p=0,000). In second week, there are significant increase inmuscle diameter for saturated ketogenic diet without exercise (P1(p=0,000)) and significantdecrease in muscle diameter for three other group (P2(p=0,000), P3(p=0,001), P4(p=0,000)). In the fourth week, there is a significant increase in muscle diameter for an unsaturated ketogenic diet with exercise (P4). Conclusion: An unsaturated ketogenic diet with exercise could increase the mass anddiameter of quadriceps muscle at the end of this research.
DIFFERENCE BETWEEN GROSS MOTOR SKILLS OF INFANTS RECEIVING BREASTMILK AND RECEIVING BREASTMILK-FORMULA MILK
Get PDFIntroduction: Development is the process of changing the functional capacity of the body's organs to a state that is increasingly organized and according to their respective functions. There are gross motor skills, fine motor skills, social skills, emotional abilities, language skills, and knowledge in the development domain. Gross motor movement is the ability to change various body positions using large muscles. Gross motor development begins before a child continues the developmental stage to the next domain. One of the factors in infant development is breastfeeding. Breastfeeding can be done as a solution to prevent delays in motor development in children.Purpose: To determine the difference between the gross motor skills of infants receiving breastmilk and receiving breastmilk-formula milk in Gotong Royong Hospital.Method: This study used an observational analytic study with a research design retro cross-sectional. The sampling technique was carried out by random sampling. The data collection procedure was carried out by collecting secondary data based on medical records from the main study, "The Impact of Early Initiation of Breastfeeding on the Health Profile of Mother and Infant in Gotong Royong Hospital". In this study, using the statistical test Chi-square then data analysis was performed using software SPSS on the computer.Results: Based on the analysis test, there was no difference in gross motor development of infants aged three months who were breastfed and those who were breastfed and received formula milk with a value of p = 1,000 (p <0,05). Babies who experienced gross motor development were suspected (42%), while those who experienced normal gross motor development were (58%).Conclusion: There is no difference in gross motor development of infants aged three months receiving breastmilk and breastmilk-formula milk in Gotong Royong Hospital
SEPTIC ARTHRITIS AFTER TOTAL KNEE REPLACEMENT IN GERIATRICS PATIENT, THE IMPORTANT OF PERIOPERATIVE CARE
Get PDFIntroduction: The geriatric population are the fastest growing segment around the world. The prevalence of multiple comorbidities in geriatric patients requiring special perioperative care. Perioperative management must be done properly, considering that surgical complications on geriatric can cause multiple comorbidities. There are many complications that often occur in geriatrics, one of which is infection.Case report: A 77-year-old man complained about pain on his right knee 1 – 2 weeks after doing TKR procedure. The pain accompanied with fever, swollen, and redness. Physical examination showed elevated blood pressure (140/90), Fever (37,4oC), obesity grade I (BMI 27.4 kg/m2), swollen and redness on his right knee, pain on palpation with VAS 5, edema (+). Barthel index ADL showed mild dependency, FRAIL score 3, qSOFA score 0. Laboratory result showed elevated leukocyte 14.900/µl.Conclusion: Geriatric patients are very vulnerable to the risks of surgery, one of which is septic arthritis. So that a good perioperative evaluation can reduce complications, comorbidities and decreased functional statu
Spontaneous Pneumothorax Following Bronchopleural Fistula In Geriatric Patient: A Case Report And Emergency Management
Get PDFIntroduction: Bronchopleural fistula (BPF) is a pathological connection between thebronchial tree and the pleural space. Clinical manifestation of BPF may be classified as acute,subacute, and delayed or chronic forms. Acute BPF can be a life-threatening condition due totension pneumothorax or asphyxiation from pulmonary flooding. Purpose: To report the patient survival from the upper lobe of the right lung bronchopleuralfistula wedge resection and to use staplers as upper lobe pulmonary wound closure. Case Report: 72-year-old male referred from pulmonologist with a chief complaint ofprogressive shortness of breath and nonproductive cough for four days. The patient had ahistory of tuberculosis and COPD and a heavy smoker for the last 50 years. Chestradiography showed a decreased opacity of the right hemithorax, with 40% collapsed of the lung parenchyma. Chest tube insertion performed on the right hemithorax, then the patient got immediate relief. On the seventh day, the patient complained of worsening dyspnea. Achest x-ray showed lung collapsed on the right hemithorax. Multislice CT-scan (MSCT) ofthe chest showed right-sided pneumothorax with bronchopleural fistula. Wedge resection forthe 3 cm in diameter fistula was performed. On the seventh day postoperative, the patient wasfully recovered then discharged from the hospital.Conclusion: Seven days postoperatively of wedge resection, the patient discharge from thehospital without any complication and stable hemodynamic. The patient went to theoutpatient department for follow up one week after
LITERATURE STUDY: THE DIFFERENCE IN RISK OF FALLS BEFORE AND AFTER CHAIR-BASED EXERCISE ON ELDERLY
Get PDFIntroduction: Indonesian Ministry of Health Research stated that in 2017 the population of the elderly reached 23.66 million people (9.03%) and also predicted that it will continue to increase. The aging process causes declined physical capacity and mental, which makes the elderly have a higher risk of falls. One of the preventions of falls in the elderly is physical exercise to increase muscle strength and joint mobility. Chair-based Exercise is a physical exercise done by sitting, consisting of aerobic and muscle resistance exercise with Thera Band.Purpose: To analyze the risk of falls in the elderly before and after Chair Based Exercise.Method: This study used literature synthesis. Keywords collected the Articles due to the topic in the research proposal.Result: 13 articles were reviewed in this study. Most articles have similarities in research design, analysis techniques, sample characteristics, total sample, duration of the intervention, and effect of the intervention studied. The differences mainly on the age of the sample and the intervention method. The similarities between the articles and research proposal mostly on sample characteristics and measuring the risk of falls. The difference mostly in a total of the sample, research design, analysis technique, duration and method of the intervention.Conclusion: Only a few articles published Chair Based Exercise as an intervention method. There are similarities in the interventions given in the form of combination training, and it was found that the risk of falls was improved in the elderly. Therefore, research on the effect of Chair Based Exercise on the risk of falls in the elderly needs to be realized by enriching various inputs from literature studies