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Study protocol for a mixed-methods pilot of a physiotherapy plus education program for inpatients with major depressive disorder: Feasibility and preliminary effects
Background
Major depressive disorder is a mood disorder with significant psychological and physical symptoms that can lead to disability and other severe consequences. This disorder is influenced by both genetic and environmental factors, causing neurotransmitter imbalances and inflammation. Given mayor depressive disorder’s high prevalence and impact, it is crucial to implement a health promotion and intervention program aimed at this disorder. Investigating the feasibility of physical therapy, including therapeutic exercise and health education, compared to psychiatric and psychological approaches is an essential component of this program and of improving the quality of life for patients affected by mayor depressive disorder.
Methods
A concurrent nested mixed-methods study with quantitative dominance will be conducted. The quantitative study will be a quasi-experimental pilot study with a pre-post design. This study will additionally include a qualitative narrative design. Initial and post-intervention evaluations will include sociodemographic and clinical data. Quantitative data will be collected using the EQ-5D-3L, MADRS, NRS, GSE, and GCPC-UN-ESU questionnaires. These tools assess health status, depression severity, pain intensity, self-efficacy, and satisfaction levels. Qualitative data will be collected from focus groups with 6–8 participants. The question guide for patients will cover their experiences with their illness and intervention, while the guide for professionals will cover their perceptions of patient management and observed barriers and facilitators. All participants will receive the same evidence-based intervention over 3–6 weeks, with 2 weekly sessions of approximately 45 minutes each. Each session will consist of therapeutic exercise and health education to improve patients’ physical condition and self-management skills.
Discussion
This study aims to evaluate the feasibility and acceptability of a physiotherapy intervention program for MDD patients. It will also provide preliminary insights into the effects on quality of life, pain, and self-efficacy, which will inform the design of a future definitive trial. The findings from this research will provide valuable scientific insights and a basis for guiding health-care policymakers on the potential inclusion of physical therapy in clinical practice guidelines and standard hospital treatments for major depressive disorders.This study has been supported by research funding of €5,700 from Universidad San Jorge (ID 2425010) and Gobierno de Aragón (B61_23D). The funders had and will not have a role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. There was no additional external funding received for this study
Storytelling y transmedia storytelling en la comunicación organizacional: tendencias a partir de un maping review
En el contexto de la comunicación organizacional o corporativa, las narraciones que sobre una organización realizan sus públicos internos y externos son fundamentales para conectar con la propia organización y conectarla con la sociedad. El objetivo de este capítulo es identificar algunas de las tendencias, en el contexto de las publicaciones académicas, sobre el storytelling y el transmedia storytelling en las organizaciones a partir de una revisión documental (maping review). ¿Cuáles son esos temas de interés científico que podrían ser considerados como aspectos claves de la comunicación organizacional actual? El aporte de estas reflexiones desea contribuir al análisis y a la reflexión de la comunicación organizacional desde perspectivas emergentes
The effect of brief, repetitive balance training on balance and fall risk in older people with stroke: A randomized controlled trial
Objective: To evaluate the effect of integrating a specific balance-training program focused on static balance to the conventional rehabilitation program on dynamic balance, risk of falls, and activities of daily living (ADLs) in older adults post-stroke. Design: A single-blinded randomized controlled trial. Setting: Institutional Intermediate Care Hospital. Subjects: Post-stroke older adults in a subacute phase without cognitive impairment, aged 65 years and older, exhibiting trunk control in a seated position for 30 seconds without supporting the arms. Intervention: The control group underwent the usual treatment, consisting of 60-minute physiotherapy sessions, 5 days per week, for 30 days. The experimental group integrated into the usual treatment 15 minutes of the balance-training program (45 min + 15 min). Main measures: Balance impairment (Mini-BESTest and Berg Balance Scale (BBS), risk of falls (BBS), and independence for ADLs (Barthel Index)) were assessed at baseline, 15 and 30 days after the start of interventions. Results: Seventy-one post-stroke patients (77.7 ± 9.0 years, 49.2% women) were randomized into the experimental (n = 35) or control (n = 36) groups. The experimental group showed improved dynamic balance at day 15 (Mini-BESTest: 2.90 [1.05-4.77], p = 0.003; BBS: 4.31 [1.41-7.23], p = 0.004) and day 30 (Mini-BESTest: 6.06 [2.85-9.27], p < 0.001; BBS: 8.24 [2.96-13.53], p = 0.003), as well as greater independence levels (11 [2.75-19.23], p = 0.010) compared to the control group. The control group showed higher risk of falls on day 15 (p = 0.035) and day 30 (p = 0.003) than the experimental group. Conclusions: A simple, easily reproducible approach designed by and for the older adult to rehabilitate post-stroke impairments effectively improved balance, functional gait, risk of falls, and ADLs
Heart rate recovery after the 6-min walk test in people with bronchiectasis
Background: The cardiac autonomic response to exercise and during recovery has
been poorly explored in bronchiectasis.
Methods: A longitudinal study was conducted in adults with bronchiectasis.
Sociodemographic and clinical data were collected at baseline and after 12 months
of follow-up. The heart rate recovery after the first (HRR1) and second minute
(HRR2) of recovery in the six-min walk test (6MWT) was estimated in both
assessments. Adjusted regression models were used to identify predictors of a
delayed HRR1 (HRR1≤14).
Results: 104 participants with a mean±sd age of 64±13 years and mostly women
(67%) were included. A delayed HRR1 after the baseline 6MWT was identified in
36% of participants. These participants presented a higher proportion of males,
increased body mass index, higher disease severity, more likely to require
hospitalisation, more impact on quality of life, lower exercise capacity, lower heart
rate at the end of the 6MWT and lower HRR2. Disease severity (β, 95% CI)
(moderate and severe versus mild, -0.47 (-0.94 to -0.01)) and distance walked (0.34
(0.11 to 0.56)) were the independent variables associated with HRR1. Of the 45
participants who completed the entire follow-up period, 24% exhibited delayed
HRR1. The presence of at least two exacerbations during the follow-up period (OR
16.89, 95% CI 1.44 to 197.48) was the only predictor of a delayed HRR1 in the
assessment completed at the end of the study.
Conclusion: HRR1 is related to disease severity and is mainly affected by having
severe exacerbations in people with bronchiectasis.This project was partially funded by SEPAR (ID 181/2011). Funding information for this article has been deposited with the Crossref Funder Registry
Fitness Profiles of Highly Trained Female Futsal Players According to Their Playing Positions
Purpose: Although women’s futsal has experienced great growth recently, few studies have analyzed the physical profiles of
female futsal players. The objectives of this study were to determine the physical and anthropometric characteristics in elite
women’s futsal using laboratory and field tests and to analyze the differences between the different playing positions. Methods:
Forty-one female futsal players from the second division of the Spanish league (age 22.69 [4.76] y; bodyheight 161.28 [6.03] cm;
body mass 62.20 [10.34] kg) were evaluated for body composition with dual-energy X-ray absorptiometry anthropometrically,
lower-body power using a force platform (countermovement jump, squat jump, and drop jump), linear speed (5, 10, 15, and
25 m), changes of direction (505 modified, V-Cut, and L-Run), and repeated-sprint ability measured through photoelectric cells.
Results: The results reveal that there are no significant differences between the physical profiles of players depending on playing
position. Despite this, wingers seem to have the best physical profiles, and goalkeepers have the highest body mass index (26.9
[4.48] vs 23.3 [2.82]; P = .069) and fat percentage (31.9 [7.81] vs 29.96 [6.08]; P = .101), but they present very similar values to
the other positions in all other tests performed, except for repeated-sprint ability (4.64 [0.45]; P = .009). Conclusion: Relevant
descriptive data were presented to provide useful information for coaches to optimize their training programs, reporting that
playing position does not identify different physical profiles in elite female futsal players.This work was supported by Universidad San Jorge (Internal Research Project 2024 2025) and Departamento de Ciencia, Universidad y Sociedad del Conocimiento from the Gobierno de Arago´n (Spain) (Research Group ValorA
No. S08_20R)
Needs analysis in an English for medical purposes course
El objetivo de este artículo es informar sobre un Análisis de Necesidades desarrollado e implementado en un curso de inglés para fines médicos, para investigar las necesidades del alumnado. Actualmente, el análisis de necesidades considera las necesidades y preferencias del alumnado de gran relevancia en el proceso de diseño curricular. El diseño del cuestionario es explicado, con preguntas que abordan las necesidades actuales del estudiantado, las necesidades definidas por el alumnado, y las necesidades subjetivas. A continuación, se presentan y analizan los resultados del cuestionario. Las necesidades actuales se centran en sus destrezas de expresión oral y escrita, mientras que las necesidades objetivo en la comunicación, expresión oral y lectura. Además, sus necesidades subjetivas incluyen la práctica de conversaciones doctor-paciente o la adquisición de vocabulario médico. Por último, cabe destacar que el análisis de necesidades es un proceso dinámico que responde a las necesidades cambiantes de los alumnos.
The objective of this article is to inform about a Needs Analysis developed and conducted in an English for Medical Purposes course, with the aim of investigating learners’ needs and preferences in order to improve course design. A report on needs analysis research is offered to explain the current view that considers learners’ needs of extreme relevance in the process of syllabus design. The design of the questionnaire is explained, with questions addressing learners’ present needs, learner-defined target needs and subjective needs. Then, the results of the survey are analysed and presented. Learners’ present needs concentrate on their speaking and writing skills, while their target needs focus on communication, speaking and reading skills. Moreover, their subjective needs include, among others, the practice of doctor-patient conversations or the acquisition of medical vocabulary. Finally, it should be stressed that needs analysis is a dynamic process, responding to learners’ changing needs
Efectividad de la estimulación transcraneal por corriente directa (tDCS) en comparación con la estimulación nerviosa eléctrica transcutánea (TENS) sobre la calidad de vida en mujeres con dolor crónico por endometriosis: protocolo de un ensayo clínico aleatorizado
Introducción: La endometriosis es una enfermedad inflamatoria y crónica en la que un tejido parecido al endometrio se desarrolla fuera de la cavidad uterina. Esto puede causar complicaciones debido a que el tejido no puede ser evacuado. Afecta aproximadamente al 10% de las mujeres en edad fértil, con importantes implicaciones biopsicosociales. Causa dolor crónico y afecta gravemente la calidad de vida de las mujeres. Sin embargo, son pocos los estudios con seguimiento a largo plazo que tratan de manera holística todas las dimensiones afectadas por esta patología.
Objetivo: El objetivo principal de este estudio es comparar la eficacia de la estimulación transcraneal por corriente continua (tDCS) y la estimulación nerviosa eléctrica transcutánea (TENS) en la calidad de vida de las mujeres que sufren dolor crónico debido a la endometriosis.
Metodología: Este estudio será un ensayo clínico aleatorizado, diseñado para comparar la eficacia de la tDCS (grupo experimental) frente al TENS (grupo control). La duración total del estudio será de 11 meses, con una intervención de 5 semanas seguida de un periodo de seguimiento de 5 meses. El objetivo primario será evaluar la calidad de vida mediante el cuestionario Endometriosis Health Profile-30 (EHP-30). Los objetivos secundarios incluyen la evaluación del dolor (Visual Analog Scale), del estado psicológico (Hospital Anxiety and Depression Scale), del consumo de analgésicos (Medication Quantification Scale IV), de la fatiga (Fatigue Severity Scale) y de la función sexual (Female Sexual Function Index).
Resultados esperados: Los resultados deseados son una mejora significativa y duradera en las variables primarias y secundarias en el grupo tDCS, mientras que el grupo TENS podría mostrar una mejora no significativa y de menor duración.
Conclusión: Aunque los resultados de la tDCS muestran una mejora en la calidad de vida y en variables secundarias, futuras investigaciones podrían explorar su combinación con técnicas como la respiración diafragmática, la imaginería motora o la educación terapéutica, con el fin de maximizar sus efectos al implicar a la paciente de forma activa en su tratamiento. Además, sería interesante evaluar el nivel físico de estas pacientes y realizar un estudio cualitativo
Investigating Countermovement and Horizontal Jump Asymmetry in Female Football Players: Differences Across Age Categories
Lower limb asymmetry is a critical factor influencing performance and injury risk in football players. Despite the increasing popularity of women’s football, limited research has examined how asymmetry varies across different age categories. This study aimed to investigate countermovement jump (CMJ) and horizontal jump (HJ) asymmetry in female football players across four age categories (U14, U16, U18, and +18). Methods: Seventy-six female football players from the same club participated in the study. Players performed unilateral CMJ and HJ tests to assess inter-limb asymmetry. A oneway ANOVA and Chi-square tests were conducted to examine age-related differences in asymmetry levels. Results: CMJ asymmetry significantly varied across age groups (p < 0.001), with the highest asymmetry observed in U14 and the lowest in +18. In contrast, HJ asymmetry remained consistently low across all age groups (p = 0.113). No significant correlation was found between CMJ and HJ asymmetry. Additionally, asymmetry levels in CMJ were significantly associated with age (p = 0.003), whereas no such association was observed for HJ. Conclusions: CMJ asymmetry is more prevalent in younger female football players and tends to decrease with age, suggesting that neuromuscular development plays a role in reducing asymmetry over time. These findings highlight the importance of monitoring asymmetry levels across different age groups to optimize training interventions and injury prevention strategies
Black mulberry (Morus nigra L.) prevents deleterious effects of excess glucose in obese C. elegans decreasing lipofuscin accumulation and ROS production
Black mulberries have been traditionally used as antidiabetic agents and are a source of nutrients and phenolic compounds, particularly anthocyanins. The objective of this work is to determine if Morus nigra berries could prevent metabolic and obesity-related disorders using in vitro systems and in vivo alternative models such as C. elegans. An aqueous solvent-free extract from Morus nigra fruits rich in phenolic compounds like chlorogenic acid, hyperoside, rutin and cyanidin 3-glucoside was evaluated in the C. elegans obese model subjected to high glucose concentrations evaluating different parameters such as lipid droplets, lipofuscin accumulation and ROS production. The capacity of the extract to inhibit advance glycation end products and free radicals as well as pancreatic lipase and α-amylase was also evaluated in vitro. The black mulberry extract showed a significant capacity to inhibit the accumulation of lipid droplets, reducing by 50.40 % the fat deposits. The extract was able to reverse the deleterious effects of excess glucose in C. elegans enhancing stress resistance, preventing the accumulation of lipofuscin, and decreasing the ROS production. The anti-glycation and antioxidant effects in vitro were higher than the reference substances aminoguanidine and quercetin respectively. Morus nigra was also able to inhibit the pancreatic enzymes α-amylase and lipase and could be considered an interesting traditional food
ingredient in the prevention of certain metabolic diseases
Integrating Telerehabilitation into the Prehabilitation and Rehabilitation Pathway in Colorectal Cancer: A Case Series
Background and Clinical Significance: Colorectal cancer (CRC) remains a global health challenge with significant postoperative complications and functional declines. Telerehabilitation offers an accessible alternative to improve preoperative physical condition and postoperative recovery. Case Presentation: Five CRC patients scheduled for laparoscopic surgery participated in an asynchronous telerehabilitation multimodal program, including two weeks of prehabilitation and four weeks of postoperative rehabilitation. Delivered via a digital platform with remote physiotherapist support, the intervention improved functional capacity and muscle strength preoperatively, with partial recovery noted post-surgery. Conclusions: Integrating telerehabilitation into the CRC surgical pathway is feasible and may enhance functional outcomes and quality of life. Further studies are required to confirm these preliminary findings