ARUd’A (Università “G. d’Annunzio CHIETI -PESCARA)
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    Greenness assessment of 174 CEN, ISO, and pharmacopoeia standard methods and their sub-methods used for environmental, food, trace element and pharmaceutical analyses

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    This work evaluates the greenness of 174 standard methods with a sample preparation step and their 329 submethod variations from CEN, ISO, and Pharmacopoeias. The methods are used in laboratories for environmental/ organic, food, trace element, or pharmaceutical analyses. The widely adopted AGREEprep metric was applied to assess the greenness of the standard methods. The discussion begins with the overall scores of each method, followed by a detailed analysis of individual criteria, that highlights the strengths and weaknesses of the evaluated sample preparation methods in terms of greenness. The findings obtained in this work reveal that many official methods still rely on resource-intensive, outdated techniques, scoring poorly on key greenness criteria. This discrepancy underscores the urgent need to update standard methods by including contemporary and mature sample preparation methods, as the traditional methodologies currently used often conflict with global sustainability efforts and increase regulatory and societal pressures. As such, this contribution serves not only as a critique of the current state of official standard methods but also as a call to action for their reform

    ISFNR Committee on Charms, Charmers, and Charming 16th annual Conference “Conflicts and Catastrophes.” Helsinki, June 12th-15th, 2024

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    The 16th annual Conference, organised by the ISFNR Committee on Charms, Charmers, and Charming, is an important event in folklore studies and cultural anthropology. This year, it was hosted in Helsinki by the Department of Folklore Studies at the University of Helsinki and the Finnish Literature Society. The Conference” eventually brought physically together researchers and scholars from fourteen different nations to discuss and share their findings on the use of rituals, charms, and traditional practices in coping with conflicts and catastrophes. The papers presented at the Conference revealed a rich variety of research focusing on conflicts and catastrophes and the various ways societies cope with them. Several key research themes emerge, including the role of rituals, charms, and traditional practices in crisis management

    Nelle grotte del Carso: percorsi letterari tra il ‘700 e l’800

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    Deciphering Barriers and Strategies in Environmental Management Accounting (EMA) Adoption: A Comprehensive Two-Decade Analysis

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    This study presents a comprehensive analysis of the evolution and challenges of Environmental Management Accounting (EMA) adoption across diverse industries and regions over the past two decades. Through a bibliometric analysis, this study categorizes the literature into three distinct periods, each elucidating crucial developments in EMA practices from initial theoretical formulations to their strategic integration with corporate sustainability and circular economy frameworks. The recent period particularly focuses on identifying the multifaceted challenges in EMA adoption, encapsulated in the newly developed "EMA adoption and application issue framework." This framework not only categorizes but also visually represents systemic barriers such as regulatory constraints, organizational and cultural resistance, economic and technical obstacles, and the influence of external market forces. The analysis reveals significant regional disparities in EMA research, with a notable lack of contribution from European Union countries compared to active regions such as Australia, South Africa, and Southeast Asia, suggesting a critical need for strategic interventions to enhance EMA research and practical implementation in the EU. These findings advocate for more robust regulations, enhanced managerial commitment, and international collaboration to improve EMA adoption rates. This study aims to advance the understanding of EMA's implementation challenges and foster dialog among academics, policymakers, and practitioners to overcome these barriers and enhance the integration of EMA into sustainability strategies globally

    Industrial Ecology and Circular Economy: past, present and future developments. insights from a bibliometric and content analysis

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    The concept of Circular Economy (CE) has reached such a level of diffusion and relevance to be considered an autonomous scientific field and also a new economic paradigm. As recognized, many of the principles and tools underlying CE are shared with the research field of Industrial Ecology (IE). To investigate the interrelationships between the two, a cross-bibliometric analysis and a subsequent content analysis of the scientific literature was conducted, considering several parameters concerning authors, countries, keywords and typical research methods and tools. Results provide insights on the origin, current state and future development of the two fields

    Alcohol Use Disorders and Suicidal Behaviour: A Narrative Review

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    Background: Alcohol Use Disorders (AUD), affective disorders, and personality disorders are among the most prevalent mental health conditions observed in individuals exhibiting suicidal behavior, encompassing both completed and attempted suicides. A robust association between AUD and suicidal behavior has been established through retrospective and prospective cohort studies. Research on the relationship between alcohol consumption and self-harm has predominantly focused on Western and high-income countries, whereas approximately one-third of the global population, including half of the world’s countries, lacks accessible suicide data. This study aims to present an updated review of empirical evidence regarding the risk of suicide associated with AUD in both developed and developing nations. Methods: We identified published meta-analyses, reviews, systematic reviews, randomized controlled trials, clinical studies, clinical trials, controlled clinical trials, observational studies, and case reports written in English and published between January 2004 and June 2024. Our search yielded a total of 312 papers. After reviewing titles and abstracts, 232 articles were excluded from the initial records. Following full-text review of the remaining 80 articles, a qualitative synthesis was conducted, highlighting the most representative 41 papers for inclusion in this overview. Results: Our analysis indicates that alcohol abuse is a significant risk factor for all forms of suicidal behavior. Alcohol consumption functions as both a predisposing and precipitating factor, contributing to maladaptive behaviors in both developing and developed countries. The clinical condition is exacerbated by alcohol use, which in turn increases the risk of suicide. Conclusions: Further research is essential to develop targeted psychological and pharmacological interventions aimed at preventing and treating these conditions, with the goal of reducing the risk of suicidal behavior associated with AUD. In developing countries, integrating public health and clinical strategies is crucial for effectively addressing suicide prevention

    Methodological Development of a Test for Salivary Proteome Analysis Useful in Lung Cancer Screening

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    Early diagnosis of lung cancer, essential for reducing its high mortality rate, is currently challenging, partly due to the lack of specific biomarkers. Here, we attempted to develop a noninvasive and potentially sensitive screening method based on the proteomic analysis of unstimulated and stimulated saliva samples, collected by passive drooling and salivary swabs, respectively, from healthy heavy smokers enrolled in a nonprofit screening project. Protein content analyzed before and after sample cryopreservation for various periods and the associated two-dimensional electrophoresis revealed that protein extraction after short-term cryopreservation prevented the loss of detectable proteins. Mass spectrometric analysis of these electrophoretically resolved proteins revealed the presence of salivary proteins whose levels may be dysregulated in various types of lung cancer. Finally, in pilot experiments conducted on stimulated saliva from a patient with a lung cancer nodule, we detected altered content or selective presence of proteins involved in lung carcinogenesis, such as serpin B3 or the proteins S100A14 and aldoketoreductase-A1, respectively. While acknowledging that these findings require further validation, we believe that the use of saliva and related proteomic analyses may contribute to the identification of potential early lung cancer biomarkers, which could hopefully improve clinical management of the tumor and patient survival

    Paleoseismological evidence of multiple, large-magnitude earthquake surface ruptures on the active Mt. Morrone normal fault, central Apennines, Italy

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    The active Mt. Morrone Fault (MMF) and the related Sulmona intermountain basin constitute one of the most characteristic examples of the extensional tectonic landscape carving the central Apennines (Italy). Above the ∼ 22 km MMF, thousands of inhabitants concentrate on a thriving reality and a historical and cultural heritage of great significance. According to current knowledge, the last activation event of the whole MMF occurred ∼ 2000 years ago, and the maximum expected magnitude is M 6.6-7.0. Thus, the MMF today constitutes one of the most problematic structures in the central Apennines seismotectonic setting in terms of large-magnitude earthquake probability. Despite this, information on the activity of the MMF is presently relatively sparse, both for associated historical seismicity and paleoseismological data. To strengthen these knowledge weaknesses, we performed new extensive paleoseismological analyses (employing four trenches) in the central sector of the fault. Our goal was to supplement the limited existing dataset, constituted by a single paleoseismological study close to the northwestern tip of the fault. Additionally, we aimed to incorporate findings from a pair of studies focused on archaeoseismological and speleoseismological secondary evidence. Through these analyses, we unveiled four significant surface rupture events of the MMF, three of which occurred over the past 6000 years BP. Specifically, the youngest identified event occurred after 3.6-3.5 kyr BP, thus being chronologically consistent with the event in the second century CE, a penultimate event after 4.4 kyr BP, a previous event that occurred after 5.4-5.3 kyr BP, and the oldest event that took place after 9-8.9 kyr and (presumably) before 5.8-5.7 kyr BP. Considering that the estimated cumulative minimum vertical displacement encompassing the last three events is ∼ 140 cm, and based on the length of the fault at the surface, we can confirm that earthquakes with M 6.6-7.0 may be expected from the activation of the MMF with an inferred average recurrence interval not longer than 1800 years over the last ∼ 5.4 kyr

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