Journals at the University of Arizona
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LYMPHOCYTE SUBPOPULATIONS IN HUMAN LYMPH NODES: A NORMAL RANGE
No full text21 nodes from control subject , 12 normal and 9 howing reactive hyperplasia. Reactive node showed significantly decreased proportion of T lymphocytes (median 44%) and increased proportion of B lymphocytes (median 32 %) when compared with normal nodes (median 68% and 18 %, respectively). The increase in B lymphocytes was seen in all immunogtobulin classes studied. The values for normalnodes were comparable with three previous studies of nodes confirmed to be normal by histology . On the other hand, the result from reactive nodes weresimilar to the majoritiy of previously published " control" nodes, many of which were histologically abnormal. The importance of ensuring that controlnodes are histologically normal is empha ized by this study
NEW APPROACH TO PROTEIN-LOSING GASTROENTEROPATHY
No full textFibrinolytic activity in the biopsicd gastrointestinalmucosa was investigated in patients with proteinlosinggastroenteropathy, and the increased activitywas observed in patients associated with erosivegastritis, Menetrier's disease, atrophic gastritis, orCrohn's disease. However, patients with intestinallymphangiectasia showed normal mucosal fibrinolysis.Antifibrinolytic therapy with tranexan1ic acid revealedsignificant therapeutic effect in the group withincreased mucosal fibrinolysis. It is concluded thattranexamic acid appeared to be successful in blockingthe yicious circle of "membrane disorder", "increasedtissue fibrinolysis", "increased vascular permeability",and "hypoproteinemia" in protein-losing gastroenteropathy
SURGICAL TREATMENT OF CHRONIC LYMPHEDEMA OF THE EXTREMITIES
No full textResults of various surgical treatments for chronic lymphedema of the extremities were described. None of the procedures was ideal, unfortunately. Advances in this field is expected
HISTOLOGICAL AND AUTORADIOGRAPHIC CHANGES IN LOCALLY IRRADIATED LYMPH NODES (AN EXPERIMENTAL STUDY ON RABBITS)
No full textThe authors studied the local effect of 3000 Rx1X-ray irradiation on the popliteal lymph nodes ofrabbits. Beside the morpho-histological descriptionautoradiography was performed after injection ofH3-thymidine in the afferent lymphatic of theirradiated knee node. The main finding is the appearenceof newly-formed germinal centers betweenthe 6- 10 days after irradiation
LYMPHOGRAPHY IN MEDIASTINAL LYMPH NODE HYPERPLASIA
No full textIn two cases of mediastinal lymph node hyperplasia lymphography was performed in an attempt to evaluate the retioperitoneal lymphatic system. Since the lymphograms show the non-spec pattern of lymphoid hyperplasia, they do not allow a differential diagnosis, but suggest that the disease is more general than hitherto suspected
THE DISTRIBUTION AND ULTRASTRUCTURE OF RENAL LYMPHATIC VESSELS PROLIFERATING IN RESPONSE TO KIDNEY INJURY IN THE DOG
No full textA study of lymphatic proliferation around the sites of chronic injury has clarified the process by which new lymphatic vessels are formed. Sterile wooden splinters were introduced through the renal capsule into the cortex and the medulla. Retrograde carbon injection of lymphatic trunks four weeks after splinter implantation revealed a profusion of new lymphatic vessels in the renal cortex with an extension of these vessels into the outer medulla of the dog. Ultrastructurally, these new lymphatic vessels were characterized by a large leading cell and absence of basement membrane and anchoring filaments. Carbon particles used as a lymphatic marker were found in both the lymphatic lumen and penetrating a small canal formed by the leading cell. Thus, the present study supports the hypothesis that new lymphatics arise from endothelial sprouts of pre-existing lymphatic vessels
LYMPHOGENIC ENTEROPATHY FROM THORACIC DUCT OBSTRUCTION
No full textA twelve year-old girl was studied with protein-losing enteropathy, confirmed by 51 Cr-labeled albumin test. Pedal lymphangiography demonstrated an obstructed thoracic duct at the level of the cisterna chyli with mesenteric reflux and lymphatic collateralization through the liver
TOPOGRAPHIC RELATIONS OF LYMPHATIC ENDOTHELIAL CELLS IN THE INITIAL LYMPHATIC OF THE INTESTINAL VILLUS
No full textThe appearances of the joint areas: where the lymphatic endothelial cells are in juxtaposition with one another in the initial lymphatic of the intestinal villus are described. The joint areas could be grouped into two main categories: simple valve-like and complicated. In the former group there were open, half-open and closed joint areas. The number of simple valves tended to increase during the distension of the lymphatic, whereas the complicated areas were numerous in compressed lymphatics. The joint areas were analysed by serial sectioning and with the successive sections their appearance was found to change from simple to complicated and vice versa. A few series of sections showed a change from a simple valve to a complicated one and to a simple one again. During this change in appearance the overlapping areas of the neighbouring endothelial cells changed their position in relation to one other and to the lumen of the lymphatic. So the originally abluminal cell was later found to be situated on the luminal side and vice versa. The change of sides seemed to occur at the complicated joint areas. The endothelial cells in the wall appeared to form large interdigitating cytoplasmic extensions between which the various types of joint areas were formed. The complicated joint areas with tight junction seemed to serve as points for effective fixing the endothelial cells together. The simple joint area between these, in addition to fixing cells together, produced valves through which interstitial fluid may drain into the lymphatic