Journals at the University of Arizona
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    INTERNATIONAL SOCIETY OF LYMPHOLOGY NEWS

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    INTERNATIONAL SOCIETY OF LYMPHOLOGY BUSINESS REPORT (1983/1985

    LYMPHSPIRATION

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    EDITORIA

    RENAL LYMPH FLOW AND COMPOSITION DURING ACETAZOLAMIDE AND FUROSEMIDE DIURESIS

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    Several lines of research suggest that renallymph is formed totally, or in part, as a filtrate ofpostglomerular blood. Even so, renal interstitial fluiddynamics is necessarily dominated by the rapidtransfer of large volumes of reabsorbate from tubularlumen to peritubular capillary. To determine the effectsof tubular reabsorption on lymph formation,renal lymph flow and composition were studiedbefore and during alterations in tubular reabsorptionproduced by diuresis. A 25% reduction in wholekidney fluid reabsorption rate did not alter renallymph flow or lymph protein concentration. A concomitantdecrease in plasma protein concentration,however, suggests that any deficit in lymph flowresulting from decreased reabsorbate content mayhave been obscured by an increase in vascular filtration.An increase in renal lymph PAH and creatinineconcentrations relative to those of arterial and renalvenous blood plasma supports this conclusion. It appearsthat renal lymph flow may be determined byboth vascular filtration and tubular reabsorption

    THE RELATION OF THE LYMPHATIC SYSTEM TO HEMOLYMPH NODES IN THE SHEEP

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    Sublumbar lymphatic drainage was examined infetal and adult sheep for potential connections withhemolymph (hemal) nodes. Despite numerous channelsentering sublumbar lymph nodes there were nolymphatic communications with hemal nodes. Inovine ruminants hemolymph nodes are separate fromthe lymphatic system

    UNUSUAL CHYLOLYMPHEDEMA OF CONGENITAL ORIGIN

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    LYMPHOGRAPHI

    TOPOGRAPHY OF INTRARENAL LYMPHATICS

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    The intrarenal topography of lymph vessels injected with India ink was examined in 32 canine kidneys. In the upper portion of the renal cortex most lymphatics were associated with subcapsular veins and tubules. In the cortical midpartion lymphatics were generally aligned with interlobular arteries and veins, glomeruli, and tubules. These lymphatics commonly encircled interlobular arteries and formed an interconnecting plexus adjacent to glomeruli. In the lower portion (i.e., corticomedullary zone), renal lymphatics passed between loops of Henle and collecting tubules

    NEONATAL LYMPHEDEMA FROM THORACIC DUCT OBSTRUCTION COMPLICATING PERCUTANEOUS INTRAVENOUS CENTRAL CATHETERIZATION

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    Percutaneous intravenous central catheter (PICC) complications are not common and generalized edema and anasarca in neonates as a complication of PICC malposition is even rarer. Documentation of the pathomechanisms of lymphedema in cases of severe anasarca in neonates is not often done. Here we document thoracic duct obstruction as the cause of lymphedema in a neonate with severe nonpitting generalized edema. Most PICC procedures should ideally be guided by point-of-care bedside ultrasound (US), and this precaution may prevent malposition of PICC lines although it will not detect subsequent migration or extravasation

    AN HISTORICAL SKETCH OF SPLENIC FUNCTION AND SPLENECTOMY

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    Ideas about the spleen's functions as a blood filter, reservoir, scavenger of red cells and immunologic communication center are traced from the ancients to the present

    PRESERVATION OF THE SPLEEN

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    Because the spleen can no longer be considered readily dispensable, a variety of alternatives to total splenectomy (splenic repair, partial resection, autotransplantation, ischemic therapy, reticuloendothelial blockade and irradiation) have been developed to preserve functioning remnants in trauma and hypersplenism. It remains unclear how much spleen adequately protects against OPSI or under persistent workload stimulus leads to recurrence of hypersplenis

    BCG-INDUCED CHANGES IN THE POST CAPILLARY VENULES OF THE GUINEA PIG LYMPH NODE

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    The post capillary venules  (PCV)  of  the  regional lymph nodes of BCG-injected  male and female gui­nea pigs were examined under light and electron microscopy. The endothelial cells showed increased height and pyroninophilia. Their cytoplasm contained increased numbers of ribosomes and polyribosomes and prominent rough endoplasmic reticulum with oc­ casionally dilated cisternae. The number of  lympho­cytes migrating through the PCV wall was also in­creased.  The  activation  of  the endothelial  cells  of PCV induced by  BCG may increase the  recirculation  of  lymphocytes  from the blood stream. These may be of importance  in  the antitumour  activity  of  BCG. In control guinea pigs  the  height  of  the  endothelial cells of PCV was significantly greater  in  the  female than in the male. After BCG injection this sex difference was still apparent

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