Journals at the University of Arizona
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CELLULAR MIGRATION STREAMS. THE INTEGRATION OF THE LYMPHMYELOID COMPLEX
No full textMr. President, may I start off bythanking you and your colleagues for thegreat honor you have done me in invitingme to be Honorary President of the NinthInternational Congress of Lymphology? Asan "old lymphatic war horse"-to use adescription often employed by CecilDrinker - it has given me the welcome opportunityof meeting many old friends, andalso making a number of new ones
LYMPH VESSELS OF THE RABBIT HEART: DISTRIBUTION AND FINE STRUCTURE IN VENTRICLES
No full textWe examined the distribution and fine morphology of small lymph channels in the rabbit heart, and particularly in the ventricular myocardium. Light microscopy showed many small subendocardial lymphatics in both ventricles and especially in the subendocardium of papillary muscles and right side of the septum. Electron microscopy revealed that the endothelial ultrastructure of these lymphatics was similar at different sites. The cytoplasm exhibited frequent adluminal expansions and contained numerous micropinocytotic vesicles opening both into the lumen and surrounding interstitium. Bundles of microfilaments, commonly arranged in a parallel fashion, were also visible. Between laminations of the endothelial wall were relatively dense, finely granular material. Intercellular contacts were characterized by cell superimpositions and interlockings, specialized junctions and occasionally maculae adherentes. The basal membrane was discontinuous and often of variable thickness. In the surrounding connective tissue, thin filaments appeared adjacent to the abluminal surface of the endothelial wall. Although the fine structure of the walls of small lymphatics in the rabbit ventricular myocardium was similar to that of small lymphatics at other sites, their distribution varied from other mammalian species
Xth INTERNATIONAL CONGRESS
No full textINTERNATIONAL SOCIETY OF LYMPHOLOGY INTERNATIONAL CONGRESS(August 26-September 2, 1985)ADELAIDE, SOUTH AUSTRALI
SPLENIC IMAGING
No full textBefore the advent of ultrasonography and computed tomography the spleen was an organ generally neglected by the radiologist. Today, there are five possible ways of splenic imaging : (1) plain radiography, (2) ultrasonography, (3) spleen scintigraphy, (4) computed tomography, and (5) splenic arteriography. The potentials and limitations of these different imaging modalities are discussed. Based upon a recent retrospective analysis of 194 cases with focal splenic lesions, an algorithmic pathway is suggested, where real-time ultrasonography is used as the first imaging method. In equivocal or negative results it is followed by CT which is the most accurate and best reproducible method. Nuclear medicine offers several important non-imaging function tests (e.g. red cell and platelet survival) but splenic scintigraphy is of minor importance except for the detection of aberrant spleens and splenic tissue. Selective splenic arteriography is rarely necessary for diagnostic purposes except the study of portal circulation but may become valuable again for transcatheter embolization (" medical splenectomy")
CLINICAL DISORDERS OF SPLENIC FUNCTION: THE SPECTRUM FROM ASPLENISM TO HYPERSPLENISM
No full textPathophysiology, clinical manifestations and treatment of splenic disorders are viewed in terms of the broad spectrum of function ranging from asplenism through hypersplenism
OVERWHELMING POSTSPLENECTOMY INFECTION (OPSI): THE CLINICAL SYNDROME
No full textCritical examination of the infectious risk following splenectomy raises questions about several widely held notions. True hazard of OPSI is difficult to quantify and probably underestimated, susceptibility is life-long, questionably altered by splenosis, and persists despite penicillin prophylaxis and vaccination against common pneumococcal serotypes
SPLENIC FUNCTIONS IN MALARIA
No full textThe spleen traps parasitized erythrocytes within its unique architecture, and this trapping function is modified during plasmodium infestation. Splenectomy dramatically exacerbates the course of experimental malarias probably through elimination of activated cordal macrophages responsible for killing intraerythrocytic plasmodia
STUDIES OF THE PHYSIOLOGY OF LYMPHATIC VESSEL BY MICRO-CIRCULATION METHODS
No full textThe study of the lymphatic system is difficult because of the tenuity of its vessels and of the transparency of lymph. MASCAGNI (6) and CRUIKSHANK (2) described the lymphatic collectors within the 18th century, although the knowledge of most peripheral lymphatics remained indefinite. Lymphography, developed by KINMONTH (4), initiated a renewed interest in the lymphatic system. Unfortunately, even though the lymph collectors and lymph nodes are thus shown, the peripheral channels are not demon strated. In addition, the visceral lymphatics remain inaccessible with this technique.Hungarian (7) and Italian (1) authors used a method based on the ligature of efferent lymphatic vessels in order to dilate the lymphatics above the occlusion. These lymphatics then appear in microscopic sections. Unfortunately, this method is not physiologic. In order to study morphological and physiological aspects of the peripheral lymphatics we chose to observe them in the living animal using a transillumination method (2-4)
INVESTIGATIONS INTO THE LYMPHATIC VESSELS AND THEIR VALVES IN THE FORE-LIMB OF THE PIG
No full textMeasurements were carried out on the Lymphatics of the fore-limb of the pig, the values recorded in tabular form and further classifi ed. In this way lymph trans port was considered, particularly through the lympho kinetic action of a drug, and by using patent blue violet