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    S-ICD Implantation Following TV-ICD: Insights into Patients with Infections and Abandoned Leads - the HONEST Cohort

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    International audienceBackground - Subcutaneous implantable cardioverter-defibrillators (S-ICDs) can be a viable option for patients with transvenous ICDs experiencing complications (rescue S-ICD). Objectives - This study sought to evaluate the outcomes of rescue S-ICD implantation using data from the HONEST French nationwide S-ICD cohort. Methods - All rescue S-ICD patients were identified. Outcomes (complications, reinterventions, and mortality) were compared between rescue and de novo S-ICD patients. Subgroup analyses were performed based on the implantation indication (infective vs noninfective) and the presence of abandoned leads. Results - Among 4,924 patients in the HONEST cohort, 651 underwent rescue S-ICD implantation (295 with infective indications, 244 with abandoned leads). Over a follow-up of 4.2 ± 2.2 years, complications and reinterventions were similar in rescue and de novo S-ICD patients (22.6% vs 21.0%; P = 0.35 and 8.7% vs 7.2%; P = 0.17, respectively), in infective and noninfective rescue S-ICD patients (21.6% vs 23.5%; P = 0.55 and 8.9% vs 8.6%; P = 0.90, respectively) and in patients with abandoned and extracted leads (24.3% vs 21.7%; P = 0.46 and 8.3% vs 9.0%; P = 0.77, respectively). Mortality was higher in rescue compared to de novo S-ICD patients (16.9% vs 10.2%; P < 0.001) and in rescue S-ICD patients with infective indications (29.2% vs 6.7%; P < 0.001) and extracted leads (21.9% vs 8.6%; P < 0.001), mainly due to a higher burden of comorbidities, as none of these parameters was independently associated with mortality in multivariate analyses. No S-ICD-related deaths were observed. Conclusions - Rescue S-ICD implantation is an acceptable option for patients with device-related complications. Lead abandonment in the setting of a noninfective indication appears to be safe. (S-ICD French Cohort Study [HONEST]; NCT05302115)

    Muriel Ubéda-Saillard et Vespasien V. Pella (ou inversement), <i>La justice pénale internationale au service de la paix mondiale</i>

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    International audience[Référence : Vespasien V. Pella, Muriel Ubéda-Saillard, La justice pénale internationale au service de la paix mondiale, Paris, Dalloz, 2023, (Tiré à part), 152 p., ISBN : 978-2-247-20886-9]La collection Tiré à part, dirigée par Marie- Angèle Hermitte et Muriel Ubéda-Saillard, se présente comme un livre à double entrée&nbsp;: la «&nbsp;quatrième de couverture&nbsp;», retournée de bas en haut, est en réalité une autre couverture&nbsp;; procédé qui permet de mettre, physiquement, deux textes «&nbsp;en miroir&nbsp;». L’un de ces textes est ancien, généralement la reproduction d’un article devenu classique en sa matière. L’autre en est le commentaire rédigé par un auteur contemporain.Au sein de cette collection, le livre ici présenté est le premier à traiter du droit pénal. Dans un sens&nbsp;: trente-neuf pages consacrées à la reproduction d’un article publié par Vespasien V.&nbsp;Pella à la RGIP 1947, texte intitulé «&nbsp;Fonctions pacificatrices du droit pénal international et fin du système traditionnel des traités de paix&nbsp;».Dans l’autre sens&nbsp;: cent neuf pages consacrées à un commentaire de Muriel Ubéda-Saillard qui actualise et interroge la pensée de Pella tout en justifiant l’intitulé de l’ouvrage ici présenté La justice pénale internationale au service de la paix mondiale

    Experimental and calculated detonation cells in gaseous ethanol-oxygen mixtures

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    International audienceLiquid alcohols (e.g., methanol, ethanol) are low-carbon, highly volatile liquid fuels commonly used in industry. The study of their detonation properties is important to prevent accidents during transportation or storage, and of practical interest as a combustion process in advanced propulsion systems designed to achieve pressure gain for more efficient combustion, such as rotating detonation engines. In this work, we experimentally analyze the 3D cellular structure of detonation in gaseous ethanol-oxygen mixtures using side-view and front-view recordings on soot foils for several equivalence ratios ranging from 0.27 to 2.13 and initial pressures ranging from 20 to 100 kPa. We calculate the mean cell width as a function of the equivalence ratio and initial pressure width using the predictive model based on graph theory and geometric probabilities, and observe good agreement with measurements

    Modèle de Diffusion avec Pont Brownien pour la translation d'image cérébrale

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    International audienceLa synthèse d'image à image par Intelligence Artificielle progresse rapidement et trouvede plus en plus d'applications dans le domaine de l'imagerie médicale. L'analyse d'imagesmultimodales joue un rôle crucial dans l'optimisation de la qualité de l'examen, mais l'acquisition deplusieurs modalités d'imagerie en milieu clinique reste coûteuse en ressources et en temps, enparticulier pour l'imagerie 3D. Pour relever ce défi, nous proposons un nouveau modèle detranslation d'image à image basé sur les modèles de diffusion avec pont brownien (BBDM), quipermet de translater des coupes 2D extraites d'une séquence d'imagerie par résonance magnétique(IRM) vers une autre. Notre approche intègre un mécanisme de diffusion guidé par un encodeurvariationnel, qui tire parti des distributions probabilistes de nos images pour améliorer la qualité dela synthèse. Nous évaluons notre méthode sur l'ensemble de données BraTS 2021, obtenant unegrande fidélité anatomique et une reconstruction fiable des régions pathologiques. Notre modèlesurpasse les méthodes de référence, avec un score de similarité allant jusqu'à plus de 90% pourcertains patients. Le rapport de reconstruction moyen est supérieur de 4,441 ± 1,234 dB auxmodèles de référence. Notamment, notre processus de diffusion ne nécessite que peu d'étapes, cequi le rend efficace en termes de calcul tout en maintenant une synthèse de haute qualité. Cesrésultats mettent en évidence le potentiel de la méthode Probabilistic-BBDM (Prob-BBDM) pourune synthèse IRM de haute qualité, offrant une étape prometteuse vers une meilleure translation desimages médicales

    Influence of force field on clay–water contact angle determination using molecular dynamics

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    International audienceClay minerals wettability is a key property for predicting water distribution and pollutant migration in natural or artificial materials. This study attempted to understand the difference in hydrophilicity due to the exchange of structural hydroxyl groups by fluorine atoms, observed in a number of clays. To this end, contact angles of water droplets on hydroxylated and fluorinated talcs were calculated from molecular simulations with two different force fields (one non-polarizable and one polarizable). In parallel, careful measurements of contact angles on a hydroxylated talc monocrystal were undertaken in order to assess the ability of the force fields to reproduce experiments. As expected, fluorinated talc was slightly more hydrophobic than hydroxylated talc for both force fields. Moreover, although the two force fields lead to fluid properties at the interface that were significantly different, the associated contact angles (and related works of adhesion) remained quite close to each other and to contact angles obtained on similar silica-type surfaces. These contact angles overestimated the experimental ones. This could be tentatively assigned to the presence of steps on monocrystal surfaces that could slightly increase the hydrophilicity of the surface, resulting in slightly lower contact angles. When analyzing more carefully the differences between both force fields, it appeared that the use of a polarizable force field resulted in a higher depletion of the fluid close to the surface. This could indicate less attraction between the fluid and the solid and a lesser constraint for the fluid

    Water hammer waves simulations using a homogeneous equilibrium model

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    International audienceWater hammer problems involving shock waves and cavitation are investigated numerically. The Homogeneous Equilibrium Model (HEM) of gas-liquid two-phase flow is considered for modeling the maximum and minimum resulting pressure waves. This is carried out using a set of conservation laws based on the continuity and momentum equations. The discretization of the model is carried out using Godunov-type finite volume technique based upon the wave propagation algorithm that mainly addresses second-order accuracy in water hammer problems. The capabilities of this model have been assessed on different cases of water hammer in air-water and CO2-water flows including the prediction of pressure, phase velocities and void fraction. Further, the wide applicability and advantageous properties of Godunov methods are demonstrated through such cases together with proper boundary conditions. Simulation results are compared with those provided by other solution techniques showing the superior accuracy as well as efficiency relations used by Godunov methods over other numerical methods. Additionally, the results are compared with experimental data available in the literature and found to be in a very good agreement. The current range of numerical simulations is discussed and illustrated including highlighting both their limitations and their advantages. Overall, this work will provide a systematic representation of past and current developments and directions for future research related to water hammer modeling nuclear power plants

    Experimental Measurement of the Near Electric Emission from LED Driver as function of Power Variation and Lighting Mode

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    International audienceThe production of static converters faces a major challenge known as electromagnetic interference (EMI), which can pose significant problems. Among the various sources of electromagnetic pollution, AC/DC energy conversions in LED lamps play an important role.This pollution is conducted through electrical cables and radiated into the air in the form of propagating electromagnetic fields. It is therefore essential to mitigate electromagnetic interference in LED lamp production to reduce the negative impact of electromagnetic pollution and ensure better electromagnetic compatibility across different systems.The objective of this paper is to examine how power variability and lighting modes influence the performance of LED spot lamps on the electric field measured by a TEKBOX electric probe, capturing the three components (EX, EY, EZ) in the spectrum domain using the near-field scanning (NFS) technique. The scanning step during the measurement process is fixed at 0.5 cm. The LED lamps in this setup are powered directly from the main, operating at 220 V and 50 Hz. Two types of lamps are used, one rated at 6 W and the other at 12 W, each offering three lighting modes: Mode 1 emits white light, Mode 2 emits colored light, and Mode 3 combines both white and colored light, providing a high degree of flexibility in terms of lighting options.During the measurement procedure, the electric field is measured above the center of the inductor. In addition, a scan is performed over the LED driver surface at specific coordinates (4 cm, 1.5 cm). This scan is used to collect data or assess specific parameters related to the performance or characteristics of the LED driver at that precise location

    Méthodes mixtes et enjeux agri-alimentaires : état des lieux et perspectives

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    Rubrique : Recherche. État de l'artInternational audienceBased on the combination of qualitative and quantitative methods of data collection, treatment and analysis, mixed methods (MM) produce enriched set of results, suited for the comprehension and analysis of complex phenomenon. In this article, the authors propose to examine the development of mixed methods for the analysis of a particular theme, namely agricultural and food issues, with a focus on the contributions of economics. From this perspective, after reviewing the history of MM, they give an inventory of current publications based on bibliometric analysis, supplemented by a lexico-metric and a content analysis. They propose a classification of these publications and reveal the limited importance of this research in economics and management. Finally, we show that, despite the large number of themes addressed, some—which are nevertheless important in today’s fields of research—are barely mentioned, suggesting avenues for future research.Reposant sur la combinaison de méthodes de collecte, de traitement et d’analyse de données à la fois quantitatives et qualitatives, les méthodes mixtes (MM) sont réputées produire des résultats riches, adaptés à la compréhension et l’analyse de phénomènes complexes. Les autrices proposent ici de rendre compte du développement des méthodes mixtes pour l’analyse d’une thématique en particulier, celle des problématiques agricoles et alimentaires, avec un focus sur les travaux en sciences économiques. Dans cette perspective, après avoir rappelé l’histoire des MM, elles donnent un état des lieux des publications scientifiques actuelles en s’appuyant sur un travail bibliométrique, complété par une analyse lexico-métrique et une analyse de contenu. Les autrices présentent ainsi une classification de ces publications et révèlent la place limitée de ces recherches en économie-gestion. Enfin, elles montrent qu’en dépit du nombre important de thématiques abordées, certaines – pourtant fortes dans les champs de recherche actuels – sont très peu présentes, suggérant des pistes pour de futurs travaux

    Malheur militant et désengagement : axes d'analyse et retour sur une trajectoire sociale

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    International audienc

    Réarrangement relatif

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    I would like to say a special thank to my wife Catherine Falaise for the typing and formatting of this document, doing also the translation via Google translator

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