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Ensuring Privacy and Security of Data in the Professional Use of LLMs
No full textThe rapid adoption of large language models (LLMs), such as ChatGPT, in professional settings introduces significant risks to privacy and data security. As employees use these tools before their organization establishes a structured approach towards LLM usage, the likelihood of sensitive data being entered grows. This master thesis addresses the question of how organizations can effectively mitigate these risks and safeguard sensitive information when using LLMs
Homesickness. Searching for a way home through an image. a visual deconstruction of homesickness as a multilayered phenomenon
No full textThe aim of this Master's thesis is to examine homesickness as a multilayered phenomenon, encompassing both physical and psychological aspects, individual and collective, as well as symbolic and material dimensions. It analyses how homesickness is constructed, shared and remembered. It develops a conceptual framework that leaves room for the creation of a personal emotional narrative. A key point of interest are photographs that can be treated as elements of distant homes. The visual language is seen here as a tool for processing and understanding homesickness, helping to find the way home. It is not about physical return, but about the search for emotional coherence, sensory familiarity and a sense of anchoring in a world where displacement – whether spatial, cultural or emotional – is present. The installation consists of individual layers containing images that overlap, blur, fragment, and disperse. This form refers to the idea of homesickness as a structure composed of elements of memory, image (also a digital one), and interpretation. The project encourages the viewer to reflect on the role of images in shaping emotional landscapes and asks how visual narratives can help us understand – and perhaps come to terms with – the feeling of being away from home. What does it mean to long for home?https://hdl.handle.net/20.500.11806/data/NextGen25-pwwpoa6
Nachfolgeplanung in Schweizer Familienbetrieben
No full textRund 88 % aller KMU in der Schweiz sind Familienbetriebe. Viele stehen vor einer Unternehmensnachfolge, die nicht nur betriebswirtschaftliche, sondern auch familiäre Dynamiken betrifft. Fehlende Vorbereitung, emotionale Spannungen und unklare Unternehmensbewertung führen oft zu Konflikten und gefährden den Fortbestand. Ziel der Arbeit war es, die zentralen Herausforderungen zu identifizieren und praxisorientierte Handlungsempfehlungen abzuleiten
Host cell protein-mediated adjuvanticity and immunogenicity risks of biotherapeutics
No full textHost cell proteins (HCPs) are process-related impurities of biotherapeutic production that might affect product quality and/or patient safety. In a few cases, adverse events were attributed to HCPs present in the administered biotherapeutic. HCP-associated immune risks include adjuvanticity and immunogenicity with potential cross-reactivity. Based on the published data, some HCPs can act as adjuvants increasing the immunogenicity of the biotherapeutic as a bystander effect. HCPs may also induce immunogenicity against themselves, resulting in anti-HCP T cell responses and anti-HCP antibody formation. Depending on sequence similarities, these anti-HCP immune responses might theoretically be cross-reactive to the biotherapeutic or human endogenous proteins. In this review, we examine HCP-associated immune-related risks reported from non-clinical and clinical studies. We also discuss the potential and limitations of in vitro and in silico methods to evaluate the adjuvanticity and immunogenicity potential of HCPs. A risk-based assessment of the safety impact of HCPs may include the identity of the HCP and similarity to the biotherapeutic and human proteins, as well as product, treatment-, and patient-related factors
Strategische Weiterentwicklung der Homeoffice-Regelung im Steueramt der Stadt Zürich
No full textDie digitale Transformation und insbesondere die COVID-19-Pandemie haben die Arbeitswelt nachhaltig verändert. Homeoffice ist heute fester Bestandteil vieler Organisationen, auch in der öffentlichen Verwaltung. Im Steueramt Zürich wurde es breit eingeführt, jedoch fehlte bislang eine fundierte Bewertung der Auswirkungen auf Produktivität, Effizienz und Zufriedenheit. Vor dem Hintergrund, dass 2024 bereits 36.9% der Erwerbstätigen in der Schweiz im Homeoffice arbeiten, gewinnt die strategische Weiterentwicklung solcher Regelungen an Bedeutung
Eli. Wanderrucksack für Rheumatiker:innen
No full textRund zwei Millionen Menschen in der Schweiz leiden an rheumatischen Beschwerden. «Eli» ist ein für diese Bedürfnisse entwickelter Wanderrucksack, der ein schmerzfreieres und selbstbestimmteres Outdoor-Erlebnis ermöglicht. Wandern lindert rheumatische Beschwerden und stärkt die Psyche. Eli unterstützt dabei, indem die einfache Nutzung des Rucksacks zum Rausgehen motiviert und so Gesundheit und Lebensqualität fördert. Die Rheumaliga Schweiz begleitete die Entwicklung mit Erfahrungen und Anforderungen. Das innovative Tragesystem erlaubt einseitiges Anziehen und entlastet die Schultern, die Eli zu einem zuverlässigen Begleiter im Gelände macht.https://hdl.handle.net/20.500.11806/data/NextGen25-65hbloj
In the case of copper. A material performance to encounter copper’s power in an anthropocentric world
No full textCurrent world views have framed non-living matter as passive and inert, in contrast to living beings – especially humans – who are seen as active agents shaping the material world. The Master's thesis "In the Case of Copper" challenges this anthropocentric paradigm by returning agency to non-living matter. Through a scenographic material performance, copper – the chemical element and metal – is staged as the main performer. The work unfolds across several experiential stations that reveal copper’s “superpowers,” tracing its journey from stellar nucleosynthesis to earthly materialization. As copper encounters other entities such as atmosphere, humans, and electricity, it undergoes a series of transformative states: from silent substance to aesthetic presence, historical artefact, and finally, a visibly and audibly active participant in electromagnetic systems. The performance invites audiences to attune themselves to the agency of matter, suggesting that copper does not simply support human action, but co-authors it. In doing so, the project reimagines materiality as vibrant, responsive, and entangled with cultural and ecological meaning.https://hdl.handle.net/20.500.11806/data/NextGen25-su3awgn
Heilig-Geist-Spital, Waisenhaus und Kinderheim. Zur wechselvollen Geschichte einer Fürsorgeeinrichtung in Einsiedeln, 1861 bis 1972
No full textÜber ein Jahrhundert prägte das Heilig-Geist-Spital in Einsiedeln das Leben zahlloser Kinder - als Armenhaus, Waisenhaus und Kinderheim. Dieser Bericht beleuchtet die Geschichte der Institution mit schonungsloser Offenheit: religiöse Strenge, fürsorgerische Kontrolle, biografische Brüche - und dennoch auch Spuren von Alltag, Nähe und Überlebenswillen.
Gestützt auf umfangreiche Archivquellen, persönliche Dokumente und 19 berührende Interviews mit Zeitzeuginnen und Zeitzeugen entsteht ein facettenreiches Bild einer Einrichtung, die lange im Schatten stand - und deren Geschichte Teil der kollektiven Erinnerung geworden ist.
Ein Stück Schweizer Sozialgeschichte, das Ungehörtem Gehör verschafft.https://www.einsiedeln.ch/verwaltung/soziales-und-gesundheit/aufarbeitung-der-geschichte-des-einsiedler-waisenhauses-und-kinderheims-1861-197
Technofuturist registers for AI and the future of work
No full textThis article contributes to sociolinguistic scholarship on register formations, digital technology, and labor by analyzing technofuturist registers—historically inherited, typified, and socially shared modes of speaking about technology. These registers create distinct modes of feeling, relating, idealizing, and desiring technology and its effects on society and our future. The focus is on recruiters’ and tech entrepreneurs’ talk about artificial intelligence (AI) as a site for the enregisterment of AI. These registers link recruitment and AI-powered job matching technologies to a broader anarcho-capitalist vision of an AI-driven future, one that both recruiters and society are encouraged to embrace. Centering technofuturist registers contributes to our understanding of contemporary language about tech, helping to understand how AI is made desirable and in so doing, how digital technology shapes the social imagination of the future and with it, reconfigures visions of labor, personhood and modernity