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Booster Vaccination with BNT162b2 Improves Cellular and Humoral Immune Response in the Pediatric Population Immunized with CoronaVac
No full textPublisher Copyright: © 2024 by the authors.The SARS-CoV-2 Omicron variant and its sublineages continue to cause COVID-19-associated pediatric hospitalizations, severe disease, and death globally. BNT162b2 and CoronaVac are the main vaccines used in Chile. Much less is known about the Wuhan-Hu-1 strain-based vaccines in the pediatric population compared to adults. Given the worldwide need for booster vaccinations to stimulate the immune response against new Omicron variants of SARS-CoV-2, we characterized the humoral and cellular immune response against Omicron variant BA.1 in a pediatric cohort aged 10 to 16 years who received heterologous vaccination based on two doses of CoronaVac, two doses of CoronaVac (2x) plus one booster dose of BNT162b2 [CoronaVac(2x) + BNT162b2 (1x)], two doses of CoronaVac plus two booster doses of BNT162b2 [CoronaVac(2x) + BNT162b2 (2x)], and three doses of BNT162b2. We observed that the [CoronaVac(2x) + BNT162b2 (2x)] vaccination showed higher anti-S1 and neutralizing antibody titers and CD4 and CD8 T cell immunity specific to the Omicron variant compared to immunization with two doses of CoronaVac alone. Furthermore, from all groups tested, immunity against Omicron was highest in individuals who received three doses of BNT162b2. We conclude that booster vaccination with BNT162b2, compared to two doses of CoronaVac alone, induces a greater protective immunity
Relación entre el sentido de comunidad y la satisfacción con la vida de adolescentes pertenecientes a una escuela de fútbol en la Región Metropolitana de Chile
Full text linkEnfermería, Licenciado en EnfermeríaIntroducción: Se entiende por comunidad una unidad simbólica asociada a la vida en común (Hombrados, 2010), que actúa como un espacio dinámico e intersubjetivo caracterizado fundamentalmente por la pertenencia, la interrelación y la cultura compartida entre sus miembros, con el objetivo de responder a las demandas del entorno y satisfacer las necesidades comunes (Krause, 2007). Por su parte, la satisfacción con la vida es la evaluación subjetiva que una persona realiza de manera global y la manera en que valora la calidad de su propia vida en relación con sus metas, expectativas y valores personales (Kammann & Flett, 2020, p. 309). Objetivo: Analizar la relación entre el sentido de comunidad y la satisfacción con la vida de adolescentes en una fundación de fútbol en Chile en el año 2024. Método: Diseño cuantitativo, descriptivo, de corte transversal. El universo serán adolescentes de adolescentes pertenecientes a una escuela de fútbol dirigida a niños en estado de vulnerabilidad, que cumplan con los criterios de inclusión: Jóvenes de 12 a 18 años, participantes activos de escuela de fútbol Gol de Oro , que estén en condiciones físicas y mentales que les permitan participar en el estudio. Se aplicarán 2 escalas: Satisfacción con la vida (5 ítems) y Sentido de Comunidad (25 ítems). Los resultados obtenidos proporcionarán información relevante para la Fundación, permitiéndoles desarrollar intervenciones acordes a la realidad de los adolescentes.Introduction: Community is understood as a symbolic unit associated with life in common (Hombrados, 2010), which acts as a dynamic and intersubjective space characterized fundamentally by belonging, interrelation and shared culture among its members, with the aim of responding to the demands of the environment and satisfying common needs (Krause, 2007). For its part, life satisfaction is the subjective evaluation that a person makes in a global way and the way in which they value the quality of their own life in relation to their goals, expectations and personal values (Kammann & Flett, 2020, p. 309). Objective: To analyze the relationship between the sense of community and life satisfaction of adolescents in a soccer foundation in Chile in 2024. Method: Quantitative, descriptive, cross-sectional design. The universe will be adolescents belonging to a football school aimed at children in a state of vulnerability, who meet the inclusion criteria: Young people from 12 to 18 years old, active participants of the Golden Goal football school, who are in physical and mental condition that allows them to participate in the study. Two scales will be applied: Satisfaction with life (5 items) and Sense of Community (25 items). The results obtained will provide relevant information for the Foundation, allowing them to develop interventions in accordance with the reality of adolescents
Abordaje vocal a personas transgéneroel camino recorrido en Chile y Argentina
No full textPublisher Copyright: © 2024. María Cano University Foundation.In recent years, there have been international references to the vocal approach for the specific group of transgender individuals, although the Latin American literature is still very timid on this matter. The purpose of this article is to identify the current norms, statistics, and vocal approach towards transgender individuals in Chile and Argentina, considering the experience of two speech and language pathologists with more than twenty years of experience on voice therapy. Reflections were made on the transgender reality in these countries, the limitations in the implementation of the depathologization of the transgender group were outlined, some current and unreliable statistics were presented, some innovative actions in the public system were highlighted, and the lack of knowledge about the benefits of vocal work for transgender men and women was discussed. The identified aspects could benefit from multicenter research that strengthens speech therapy actions with this group, contributing to de-pathologization and positive approach
Multi-Species Biofilm Interactions and Their Impact on the Biocorrosion of Copper-Coated CoCr Alloys in Dental Application
No full textPublisher Copyright: © 2024 by the authors.Biocorrosion of materials used in dental restorations is a complex process involving various bacterial species that coexist as biofilms. Since copper possesses excellent antibacterial properties, it could help minimize this problem. The aim of this study is to assess the antibiofilm characteristics and corrosion resistance of CoCr and copper-coated CoCr alloys in a multispecies biofilm model. CoCr alloys and CoCr coated with copper (CoCr/Cu) using Physical Vapor Deposition (PVD) were investigated. The samples were incubated in media with and without a multispecies biofilm for 24 h and for 15 days. Potentiodynamic Polarization and Electrochemical Impedance Spectroscopy (EIS) were used to assess the corrosion behavior of the samples. Scanning Electron Microscopy (SEM) was utilized to observe the growth of multispecies biofilms and the type of corrosion. The Mann–Whitney U test was employed to examine corrosion results, with significant differences defined as p < 0.05. CoCr/Cu alloys demonstrated superior corrosion resistance at 24 h and 15 days in the presence of biofilm compared to those without coating. No differences were observed in multispecies biofilm formation at 24 h. The study demonstrates that copper-coated CoCr alloys (CoCr/Cu) exhibit a more positive corrosion potential (Ecorr) compared to uncoated CoCr alloys, both in the presence and absence of multispecies biofilm (BP) at 24 h and 15 days. After 15 days, the potential of CoCr/Cu with BP was −0.144 V, compared to −0.252 V for uncoated CoCr. These significant differences in Ecorr values underscore the protective effect of copper against corrosion in multispecies biofilm environments
Barreras para el aprendizaje y la participación en el proceso lector en estudiantes de primer ciclo escolar (1° a 4° Básico) en contexto de post-confinamiento
Full text linkPedagogía en Educación Diferencial Advance, Licenciado en EducaciónEl propósito de este trabajo de investigación es presentar las barreras de aprendizaje y participación en el proceso lector en contexto post confinamiento de los estudiantes de primer ciclo básico. Este estudio permitirá identificar, caracterizar, describir y analizar las barreras de aprendizaje y participación del ciclo mencionado anteriormente en un contexto educativo particular, particular subvencionado y municipal, proponiendo lineamientos que permitan minimizar y/o eliminar las barreras relacionadas con el proceso lector basadas en estrategias de diversificación y de accesibilidad curricular, transitando a una cultura inclusiva y con acceso universal al proceso de enseñanza aprendizaje.
Esta problemática surge de la observación directa de los procesos de prácticas de las docentes en formación, así como de los docentes que trabajaban en el primer ciclo, que al regresar a la presencialidad tras el confinamiento por la pandemia Covid-19, notaron la presencia de barreras de aprendizajes y participación en sus estudiantes. A partir de esta problemática, el presente trabajo surge al considerar la lectura como una herramienta primordial para el aprendizaje de las otras ciencias. En consecuencia, el niño o niña que no lee presentará barreras para acceder al lenguaje escrito y a la vez como proceso integral, siendo una de las bases de la interacción y crecimiento social.
Mediante la adquisición del proceso lector, el niño o niña será guiado hacia un pensamiento crítico y reflexivo, permitiéndoles comparar, relacionar y buscar fuentes de información. Se despliegan sustentos teóricos como antecedentes relevantes que hacen referencia al tema planteado.The purpose of this research work is to present the barriers to learning and participation in the reading process in a post-confinement context in the 1st basic cycle. This study will make it possible to analyze, identify, characterize and describe the barriers to learning and participation of those in the aforementioned cycle in a particular subsidized educational context, proposing guidelines that allow minimizing and eliminating the barriers related to the reading process based on strategies of diversification and curricular accessibility, transitioning to an inclusive culture with universal access to the teaching-learning process. This problem arises from the direct observation of the internship processes of the teachers in training and of the teachers who worked in the first cycle, who upon returning to face-to-face learning noticed the presence of barriers to learning and participation in their students. From this, the problem gave rise to the work, it arises to consider reading as essential tools for the learning of the other sciences. Consequently, the child who does not read will have barriers to access written language and at the same time as an integral process, these being one of the bases of social interaction and growth. Through the acquisition of the reading process, the child will be guided to critical, reflective thinking, allowing them to compare, relate information, and look for sources of information. Various national and international studies and analyses indicate that there are significant gaps and barriers in the post-confinement reading process
Development of a Model for Predicting Mortality Among Patients Hospitalized with COVID-19 During Their Stay in a Clinical Centre
No full textPublisher Copyright: © 2024 by the authors.Background: Various tools have been proposed for predicting mortality among patients hospitalized with COVID-19 to improve clinical decision-making, the predictive capacities of which vary in different populations. The objective of this study was to develop a model for predicting mortality among patients hospitalized with COVID-19 during their time in a clinical centre. Methods: This was a retrospective study that included 201 patients hospitalized with COVID-19. Mortality was evaluated with the Kaplan–Meier curve and Cox proportional hazards models. Six models were generated for predicting mortality from laboratory markers and patients’ epidemiological data during their stay in a clinical centre. Results: The model that presented the best predictive power used D-dimer adjusted for C-reactive protein (CRP) and oxygen saturation. The sensitivity (Sn) and specificity (Sp) at 15 days were 75% and 71.9%, respectively. At 30 days, Sn was 75% and Sp was 75.4%. Conclusions: These results allowed us to establish a model for predicting mortality among patients hospitalized with COVID-19 based on D-dimer laboratory biomarkers adjusted for CRP and oxygen saturation. This mortality predictor will allow patients to be identified who require more continuous monitoring and health care
Emociones y entropía en la toma de decisiones de equipos en dinámicas de aprendizaje caóticas
No full textPublisher Copyright: © (2024), (Centro de Informacion Tecnologica). All Rights Reserved.The main objective of this research study is to determine the relationship between entropy and behaviors that optimize learning decision-making among student teams during an experimental physics science class. An initial condition (IC) is applied by using a very short video with apparently unrelated content, emerging as a discovery the question that must be answered by each team and its experiment. The behaviors displayed are transformed into time series that are analyzed with a chaos theory software. The results show that the emotions time series, in chaotic dynamics, show that entropy has the highest thermal correspondence, positively influencing team collaborative learning while favoring each student’s training. It is concluded that using ICs within a context, at the beginning of a class, is suitable for inducing a positive emotional disposition among student teams that are committed to an experimental physics course
Teaching practices in a Psycholog y programthe perspective of students
No full textPublisher Copyright: © 2016 Asociación Nacional de Universidades e Instituciones de Educación Superior A.C.The objective of this research is to analyze the perceptions of the students of the Advance Psychology program at the Patagonia campus of the Universidad San Sebastián (USS) about the teaching practices applied by the academics of the career. Data collection was carried out through semi-structured interviews and a focus group. Students show a high concern for their learning and the teaching practices that facilitate it, there being coherence between their perceptions and the teaching practices that theory suggests favor learning and identifying practices that are not sufficiently widespread, especially in learning assessment.El objetivo de esta investigación es analizar las percepciones de los estudiantes de la carrera de Psicología Advance de la sede Patagonia de la Universidad San Sebastián (USS) sobre las prácticas docentes aplicadas por los académicos de la carrera. La recolección de datos se realizó a través entrevistas semiestructuradas y grupo focal. Los estudiantes demuestran una alta preocupación por su aprendizaje y las prácticas docentes que lo facilitan, existiendo coherencia entre sus percepciones y las prácticas docentes que la teoría sugiere que favorecen el aprendizaje e identificando prácticas que no están suficientemente extendidas, sobre todo en evaluación de aprendizaje
Algoritmos mejorados de selección de red para entornos IoT domésticos con sistemas híbridos VLC/RF
No full textPublisher Copyright: AuthorsThe impending scarcity of the radio frequency (RF) spectrum has led to a boom in the development of complementary technologies such as visible light communication (VLC). Hybrid systems that complement both technologies have demonstrated numerous advantages in terms of data rate, bandwidth, and security. However, the successful operation of a hybrid VLC/RF network is highly dependent on the network selection process. In this paper, three network selection algorithms are proposed for hybrid VLC/RF systems in an indoor Internet of things (IoT)-home scenario. The proposed algorithms consider the signal-to-noise ratio (SNR), the available capacity of each network, the number of devices connected to each network, and the users’ location within the scenario. Each algorithm analyzes the data load requirements of each mobile terminal and IoT device according to these metrics. Based on this evaluation, the network that offers the best benefit in terms of signal quality, capacity, and throughput is selected. The numerical results show that the VLC network presents higher SNR values, especially for users near its access points. In addition, a higher bandwidth, a higher connection capacity, and an improvement in the quality of service are perceived from these positions. The three proposed selection algorithms presented good overall performance of the hybrid system, with the Analytical Algorithm offering the best performance for connected users, superior to the Sequential Algorithm by an average of 15.9%. The network selection algorithms efficiently allocated the maximum number of users for the VLC network, improving overall system performance and reducing the RF network data load.The impending scarcity of the radio frequency (RF) spectrum has led to a boom in the development of complementary technologies such as visible light communication (VLC). Hybrid systems that complement both technologies have demonstrated numerous advantages in terms of data rate, bandwidth, and security. However, the successful operation of a hybrid VLC/RF network is highly dependent on the network selection process. In this paper, three network selection algorithms are proposed for hybrid VLC/RF systems in an indoor Internet of things (IoT)-home scenario. The proposed algorithms consider the signal-tonoise ratio (SNR), the available capacity of each network, the number of devices connected to each network, and the users’ location within the scenario. Each algorithm analyzes the data load requirements of each mobile terminal and IoT device according to these metrics. Based on this evaluation, the network that offers the best benefit in terms of signal quality, capacity, and throughput is selected. The numerical results show that the VLC network presents higher SNR values, especially for users near its access points. In addition, a higher bandwidth, a higher connection capacity, and an improvement in the quality of service are perceived from these positions. The three proposed selection algorithms presented good overall performance of the hybrid system, with the Analytical Algorithm offering the best performance for connected users, superior to the Sequential Algorithm by an average of 15.9%. The network selection algorithms efficiently allocated the maximum number of users for the VLC network, improving overall system performance and reducing the RF network data load
“Plan de mejora al financiamiento y posicionamiento de una empresa familiar de Transporte
No full text“Transportes, Logística y Distribución Alvear Meyer Sociedad Limitada” es una empresa
familiar en el sector de transporte y logística, operando desde 2014 y constituida como
sociedad limitada en 2020. La empresa se enfoca en el transporte de materiales para la
construcción y servicios de almacenamiento y distribución. Aunque ha mantenido un buen
nivel de servicio, enfrenta problemas significativos en su gestión operativa y financiera,
incluyendo falta de procedimientos estandarizados, problemas de liquidez, y un alto nivel
de endeudamiento.
Este informe examina la situación actual de la empresa mediante un análisis de sus ratios
financieros y procesos operativos. Se identifican áreas críticas que requieren mejoras y se
presentan recomendaciones para optimizar la eficiencia operativa, mejorar la estabilidad
financiera y fortalecer la posición competitiva en el mercado. Las propuestas están dirigidas
a abordar los problemas actuales y facilitar un crecimiento sostenible a largo plazo.“Transportes, Logística y Distribución Alvear Meyer Sociedad Limitada” is a family business
in the transportation and logistics sector, operating since 2014 and incorporated as a limited
company in 2020. The company focuses on the transportation of construction materials and
storage services. and distribution. Although it has maintained a good level of service, it faces
significant problems in its operational and financial management, including lack of
standardized procedures, liquidity problems, and a high level of debt.
This report examines the current situation of the company through an analysis of its financial
ratios and operating processes. Critical areas requiring improvement are identified and
recommendations are presented to optimize operational efficiency, improve financial
stability and strengthen competitive position in the market. The proposals are aimed at
addressing current problems and facilitating long-term sustainable growth