MAU GCRIS Standard Database (Mardin Artuklu University)
Not a member yet
7418 research outputs found
Sort by
Determination of the Protective Effect of Curcumin Against Tartrazine-Induced DNA Damage and HSP 70 in the Rat Brain
No full textYavas, Mehmet Cihan/0000-0002-2923-050X;Tartrazine is a widely used food dye, and children often consume large amounts of food products containing this additive due to their appealing appearance. Curcumin, on the other hand, is known for its antioxidant properties. The aim of this study was to investigate the protective effects of curcumin on brain tissue and biochemical parameters in rats exposed to short-term tartrazine administration. Male Wistar albino rats were randomly divided into five equal groups. Group 1 served as the control; Group 2 received tartrazine (10 mg/kg); Group 3 received tartrazine (100 mg/kg); Group 4 received tartrazine (10 mg/kg) along with curcumin (20 mg/kg); and Group 5 received tartrazine (100 mg/kg) along with curcumin (20 mg/kg). All substances were administered via oral gavage. The study lasted for 21 days. Serum samples were analyzed for heat shock protein 70 (HSP70) levels using the ELISA method. Brain tissues were subjected to histopathological examination and DNA damage assessment using the comet assay. Although HSP70 levels increased in the tartrazine groups, the differences were not statistically significant (p = 0.065). Partial damage was observed in the histopathological analysis. Comet assay results indicated a dose-dependent increase in DNA tail percentage with tartrazine, which was reduced following curcumin administration. These findings suggest that curcumin may alleviate tartrazine-induced damage in brain tissue and may have a regulatory effect on serum HSP70 levels in rats
The Relationship Between Family Nutrition and Physical Activity Practices and Physical Activity Attitudes in Children
No full textIntroduction Childhood obesity and sedentary lifestyles are growing public health concerns, with familial practices playing a critical role in shaping children's physical activity attitudes. The influence of family attitudes and behaviours regarding nutrition and exercise has been highlighted as a pivotal determinant in promoting healthier choices among children. This study aims to explore the relationship between family nutrition and physical activity practices and children's attitudes toward physical activity. Methods A descriptive cross-sectional study was conducted with 633 children and their parents from a tertiary hospital in eastern Turkey. Data were collected using three tools: (1) a sociodemographic form, (2) the Family Nutrition and Physical Activity Screening Scale (FNPASS), and (3) the Youth Physical Activity Attitude Scale in Children and Young People. Data were analysed using SPSS software and statistical analyses included Pearson correlation, linear regression, and ANOVA to explore associations and group differences. Results Family nutrition and physical activity practices significantly predicted children's physical activity attitudes. Physical activity positive attitudes (mean score: 3.74 +/- 0.88) correlated strongly with healthier family practices (FNPASS mean: 52.44 +/- 7.65; r = 0.648, p < 0.01), while physical activity negative attitudes (mean: 2.46 +/- 0.92) showed inverse relationships (r = -0.596, p < 0.01). Higher parental education, urban residency, and income levels were associated with more physical activity positive attitudes (p < 0.001). Underweight children had higher positive attitude scores than overweight/obese peers (p < 0.001). Conclusion Family environments significantly influence children's physical activity attitudes, with socioeconomic factors acting as key modifiers. This study demonstrates that family nutrition and physical activity practices significantly influence children's attitudes toward physical activity. Healthier family habits correlated with more positive attitudes in children, particularly among families with higher parental education and urban residency. Public health initiatives should focus on educating parents about healthy practices while ensuring equitable access to physical activity opportunities for children
Evaluation of the Relationship Between Neuroleadership Levels of School Principals and Teachers' Job Satisfaction According to the Perceptions of Teachers
No full textBu araştırma öğretmen algılarına göre okul müdürlerinin nöroliderlik düzeyleri ile öğretmenlerin iş doyumu arasındaki ilişkiyi incelemeyi amaçlamaktadır. Araştırmada, nicel araştırma yöntemlerinden ilişkisel tarama modeli kullanılmıştır. 2024-2025 eğitim-öğretim yılı itibariyle Şanlıurfa ilinin Viranşehir ilçesinde yer alan okul öncesi, ilkokul, ortaokul ve lise kademelerinde görev yapan 2910 öğretmen, araştırmanın evrenini oluşturmaktadır. Örneklem ise evreni temsil ettiği düşünülen 342 öğretmenden oluşmaktadır. Araştırmanın örneklem yöntemi basit tesadüfi örnekleme olarak belirlenmiştir. Araştırmanın veri toplama sürecinde üç araçtan yararlanılmıştır: Kişisel Bilgi Formu, araştırmacı tarafından geliştirilen Nöroliderlik Ölçeği ile Ho ve Au (2006) tarafından geliştirilen ve Demirtaş (2010) tarafından Türkçeye uyarlaması yapılan İş Doyumu Ölçeği. Araştırma kapsamında elde edilen verilerin analizinde, SPSS programından yararlanılmıştır. Veri analiz sürecinde, öğretmenlerin okul yöneticilerinin nöroliderlik yeterliliklerine ve kendi iş doyum düzeylerine ilişkin algılarını belirlemek amacıyla aritmetik ortalama ve standart sapma değerlerinden yararlanılmıştır. Öğretmen algılarının kişisel değişkenler doğrultusunda incelenmesinde, verilerin normal dağılım göstermemesi nedeniyle parametrik olmayan istatistiksel yöntemlerden Mann-Whitney U testi ve Kruskal-Wallis testi tercih edilmiştir. Nöroliderlik ile iş doyumu arasındaki ilişkiyi belirlemek amacıyla ise Spearman Rho sıralama korelasyon katsayısından yararlanılmıştır. Araştırma bulgularına göre öğretmenlerin, yöneticilerinin nöroliderlik yeterliliklerine ilişkin tüm alt boyutlarda 'katılıyorum' düzeyinde, iş doyumuna ilişkin ise ölçek toplamında 'katılıyorum' düzeyinde algıya sahip oldukları tespit edilmiştir. Buna ek olarak, yapılan korelasyon analizi sonucunda, öğretmenlerin nöroliderlik yeterlilik algıları ile iş doyumu algıları arasında orta düzeyde ve pozitif yönlü bir ilişki olduğu görülmüştür. Nöroliderliğin alt boyutları ile iş doyumu arasında en güçlü ilişkinin nöroliderliğin özerklik alt boyutunda, en zayıf ilişkinin ise netlik alt boyutunda olduğu görülmüştür. Ayrıca okul müdürlerinin nöroliderlik yeterliliğinin öğretmen iş doyumunun anlamlı bir yordayıcısı olduğu ve iş doyumunda yaşanan değişimin %14'ünü açıkladığı tespit edilmiştir. Bu verilerden hareketle, öğretmenlerin iş doyumunu artırmak için okul müdürlerinin liderlik becerilerini güçlendirmeye yönelik nöroliderliğin tüm boyutlarını kapsayacak hizmet içi eğitimlerin düzenlenmesi önerilebilir.This research aims to examine the relationship between school principals' level of neuroleadership and teachers' job satisfaction according to the teachers' perceptions. The relational screening model, one of the quantitive research designs, was used in this research. As of the 2024-2025 academic year, the universe of the study consists of 2910 teachers working at preschools, primary schools, secondary schools and high schools in Viranşehir district of Şanlıurfa province. The sample consists of 342 teachers who are considered to represent the universe. The sampling method of the study was determined as simple random sampling. During the data collection process, three tools were utulized: the Personal Information Form, the Neuroleadership Scale developed by the researcher and the Job Satisfaction Scale developed by Ho and Au (2006) and adapted into Turkish by Demirtaş (2010). The data obtained within the scope of the research were analyzed using the SPSS software. In order to determine teachers' perceptions regarding school principals' neuroleadership competencies and their own levels of job satisfactions, arithmetic mean and standard deviation values were calculated. Since the data were not normally distributed in the examination of teachers' perceptions according to personal variables, Mann- Whitney U test and Kruskal-Wallis test, non-parametric statistical methos, were employed. In order to determine the relationship between neuroleadership and job satisfaction, the Spearman's Rho Rank Correlation Coefficient was used. According to the research findings, it was determined that teachers perceived their administrators' neuroleadership competencies at the 'agree' level in all sub-dimensions, and their job satisfaction at the 'agree' level in the overall scale. Additionally, as a result of the correlation analysis, it was seen that there was a moderate-level and positive relationship between teachers' perceptions of neuroleadership competence and their perceptions of job satisfaction. Among the sub-dimensions of neuroleadership, the strongest correlation with job satisfaction was found in the autonomy sub-dimension, while the weakest was observed in the certainty sub-dimension. Furthermore, it was determined that school principals' neuroleadership competencies significantly predict teachers' job satisfaction and explain 14% of the variance in job satisfaction. Based on these findings, it can be recommended that in-service training programs be organized to enhance school principals' leadership skills by incorporating all dimensions of neuroleadership, with the aim of increasing teachers' job satisfaction
The Effect of Low Dose Caffeine Powder Supplementation on Serve Speed, Spike Speed, and Speed-Endurance in Elite Sitting Volleyball Players: A Randomized Double-Blind Crossover Study
No full textBackgroundSitting volleyball relies heavily on upper-body strength and anaerobic capacity. Serve, spike, and speed-endurance are decisive skills, yet the ergogenic potential of low-dose caffeine in this Paralympic sport remains unclear.PurposeTo examine the acute effects of low-dose caffeine (3 mg/kg) supplementation on serve speed, spike speed, and speed-endurance in elite sitting volleyball players.MethodsUsing a randomized, double-blind, crossover design, 13 elite male athletes from the Turkish National Sitting Volleyball Team completed serve speed, spike speed, and speed-endurance tests under caffeine (CAF) and placebo (PLA) conditions.ResultsCaffeine intake produced a moderate improvement in serve speed (p = 0.028, d = 0.460); however, this effect did not remain statistically significant after Bonferroni correction (adjusted p = 0.084). No significant effects were observed for spike speed (p = 0.547, d = 0.166) or speed-endurance performance (p = 0.709, d = 0.111). Perceived exertion during the speed-endurance test was similarly high in both conditions.ConclusionsLow-dose caffeine may offer a trend toward improved serve performance, but the effect was not robust after statistical adjustment, and no benefits were observed for spike speed or speed-endurance. These findings highlight that caffeine's ergogenic effects are context-dependent and shaped by task complexity and sport-specific motor demands. Further research with larger and more diverse samples, genotype-based subgroups, and varied dosing strategies is warranted to clarify caffeine's role in adaptive sports.Trial registrationThe randomized controlled trial was retrospectively registered on 21/06/2025 at ClinicalTrials.gov, under the registration number NCT07056231
Devlet Kırılganlığı Ekonomik Büyümeyi Etkiler mi? Kırılgan Sekizli Ülkeler Üzerine Ampirik Bir Çalışma
No full textEkonomik büyüme, yaşam standartlarını yükseltmek ve refah düzeyini artırmak için hayati bir öneme sahiptir. İktisadi faktörlerin yanı sıra kurumsal faktörler de ekonomik büyümenin belirleyici unsurlarındandır. Mevcut çalışmada devlet kırılganlığının, gayri safi sabit yatırımların ve doğrudan yabancı yatırım girişinin ekonomik büyüme üzerindeki etkisi Kırılgan Sekizli (Arjantin, Brezilya, Şili, Hindistan, Endonezya, Rusya, Güney Afrika ve Türkiye) ülke grubu için 2006-2022 dönemi yıllık verileri ile incelenmektedir. Çalışmada öncelikle hem modelin hem de serilerin yatay kesit bağımlılığı kontrol edilmiştir. Daha sonra serilerin birim kök sınaması Pesaran (2007) tarafından geliştirilen CADF birim kök testi ile incelenmiştir. Panel ARDL-PMG yöntemi ile seriler arasındaki eşbütünleşme ilişkisi araştırılmıştır. Emirmahmutoğlu-Köse Nedensellik testiyle seriler arasındaki ilişkilerin yönünü belirlenmeye çalışılmıştır. Çalışmadan elde edilen ampirik sonuçlar, devlet kırılganlığındaki %1’lik bir artışın ekonomik büyümeyi yaklaşık %0,15 oranında azalttığını göstermektedir. Söz konusu dönemde gayri safi sabit yatırım ekonomik büyümeyi pozitif, doğrudan yabancı yatırım geliri ekonomik büyümeyi negatif etkilemektedir. Çalışmada ayrıca kırılganlık ile ekonomik büyüme; kırılganlık ve gayri safi sabit yatırımlar arasında çift yönlü nedensellik ilişkisi bulunmuştur. Kırılganlık, yatırım ve ekonomik büyüme ortamını doğrudan etkilediğinden politika yapıcılar politik, sosyal ve ekonomik ortamı düzenleyici güçlü kurumsal yapılar inşa etmelidir
Nasiruddin Shah Period in Iran (1848-1896)
No full textBu tez, 19. yüzyılın ikinci yarısında İran tahtına oturan Nasırüddin Şah'ın uzun süren hükümdarlığı boyunca yürüttüğü reform girişimlerini, merkeziyetçilik politikalarını ve dış ilişkilerdeki yönelimlerini çok katmanlı bir dönüşüm süreci içinde ele almaktadır. Şah'ın siyasal tarzı, reform çabaları ve iktidarını pekiştirme stratejileri kurumsal yeniden yapılanmayı önceleyen bir yön taşımış; ancak toplumsal direnç, dış müdahaleler ve idari yapının kırılganlığı bu girişimlerin etkisini sınırlamıştır. Çalışma, devlet aygıtında hedeflenen yapısal dönüşümleri; toplumsal eşitsizlik, kültürel gerilimler ve modernleşmenin sınırlı toplumsal yankıları eşliğinde tartışmaktadır. Ayrıca büyük güçlerle kurulan diplomatik ilişkilerin yalnızca siyasi dengeleri şekillendirmekle kalmayıp, ekonomik bağımlılığı artırarak toplumsal huzursuzluğu derinleştirdiği ortaya konmuştur. Nasırüddin Şah bu çalışmada, dönemin dönüşüm dinamiklerine yön veren etkili bir özne olarak ele alınmaktadır. Onun iktidarı, İran'ın geç-modernleşme sürecini kavramak açısından güçlü bir çözümleme ekseni sunmakta; bu sürece içkin olan yapısal açmazları ve tarihsel imkanları birlikte anlamayı mümkün kılmaktadır.This dissertation examines the reform initiatives, centralization policies, and foreign policy orientations pursued by Nāṣer al-Dīn Shāh throughout his long reign during the second half of the 19th century, situating them within a multilayered process of transformation. The Shah's political style, reformist ambitions, and strategies for consolidating power reflected an intent to reconstruct the state apparatus; yet these efforts remained constrained by social resistance, external pressures, and the fragility of administrative structures. The study analyzes the envisioned structural changes in the state apparatus in relation to patterns of social inequality, cultural tensions, and the limited societal reception of modernization. It also demonstrates how diplomatic engagements with major powers not only reshaped the political balance but also intensified economic dependency and deepened social unrest. In this context, Nāṣer al-Dīn Shāh is approached as a pivotal agent who actively shaped the dynamics of transformation in his time. His reign offers a critical analytical framework for understanding the opportunities and limitations embedded in Iran's late modernization process
In Vitro Cytotoxicity and Antioxidant Evaluation of Oak (Quercus Sp.) and Hazelnut Shell (Corylus Avellana L.) Pyrolized Wood Vinegar: Mtt Assay and Cuprac Results
No full textSabancilar, Ilhan/0000-0002-0773-2752Wood vinegar, also known as pyroligneous acid, is an organic liquid byproduct of wood pyrolysis, rich in compounds such as acetic acid, phenols, and ketones. This study aimed to evaluate the antioxidant and anticancer properties of wood vinegar derived from oak (Quercus sp.) residues (WVO) and hazelnut shells (Corylus avellana L.) (WVH) under in vitro conditions. Method: Wood vinegars obtained from oak trash and hazelnut shell waste were tested for biological activity. The antioxidant capacity was assessed using the copper(II) reducing antioxidant capacity (CUPRAC) method. Cytotoxic effects were evaluated using the MTT assay on healthy human endothelial cells (HUVEC) and two cancer cell lines (HT29-colon adenocarcinoma and U2OS-osteosarcoma) at concentrations ranging from 1.25% to 20% (v/v) over 24, 48, and 72-hour exposure periods. The results revealed significant interactions between vinegar type, concentration, and exposure duration. Notably, the 10% and 20% (v/v) concentrations produced significantly different absorbance values compared to lower concentrations across all time points. A dose-dependent decrease in cell viability was observed, particularly in the cancer cell lines, while healthy cells exhibited relatively higher resistance. The study demonstrates that wood vinegar exhibits promising antioxidant and selective anticancer properties, with cytotoxic effects being more pronounced at higher concentrations. These findings suggest that wood vinegar may offer potential as a natural anticancer agent. Further research is warranted to elucidate the underlying mechanisms and to explore their possible therapeutic applications
Unveiling the Ameliorative Effects of Soil-Mediated Nano-Biochar and Calcium Oxide Nanoparticles on Drought Tolerance in Oryza Sativa: Insights into Biochemical Responses, Reactive Oxygen Species, Photosynthetic Pigments and Nutrient Homeostasis
No full textFaizan, Mohammad/0000-0002-3952-6558;This study investigates the synergistic effects of calcium oxide nanoparticles (CaO NPs) and nano-biochar (nano-BC) on drought-stressed rice (Oryza sativa), a combination that has not been extensively explored in previous research. While individual applications of NPs or BC have been studied, the concurrent use of CaO NPs (as foliar spray) and nano-BC (as soil amendment) offers a novel integrative approach for enhancing drought resilience. The study demonstrates that, this combined application significantly mitigates drought-induced damage, as evidenced by improvements in physiological and biochemical traits. Notably, the treatment enhanced net photosynthetic rate (P-N) by 96.46%, stomatal conductance (gs) by 93.75%, and total soluble sugar (TSS) by 95.22% compared to drought-stressed plants. It also improved protein content, nitrogen accumulation, and transpiration rate. Additionally, reductions of 56% in malondialdehyde (MDA) and 59% in hydrogen peroxide (H2O2) indicate alleviation of oxidative stress. These findings provide new insights into the potential of nanomaterial-based interventions for sustainable rice cultivation under water-limited conditions, offering a promising strategy to improve crop resilience in the face of climate change.Strategic Academic Leadership Program of the Southern Federal UniversityVDR acknowledge support by the Strategic Academic Leadership Program of the Southern Federal University ("Priority 2030")
The Aspects of Qur'anic Verses Cited as Evidence in Ibn Jinnī's 'Al-lumaʿ Fi'l-ʿArabiyya
No full textİstişhâd, Arap dilinde var olan bir kuralın veya kelimenin anlamını temellendirmek amacıyla doğruluğu kesin olan şiir ve nesirden örnek vermektir. İstişhâdın temel kaynaklarını Kur'ân, hadis, şiir ve güvenilir Arap kelamı oluşturmaktadır. Arap dili âlimleri, Kur'ân ile yapılan istişhâdı en uygun yöntem olarak değerlendirmiş ve Arapça açısından en güvenilir kaynak olduğunu vurgulamışlardır. Nahiv, sarf ve lügat alanlarında te'lif edilen eserlerde sıklıkla âyetlerle istişhâda başvurulmuştur. Musulda yetişmiş olan ve dönemin ender şahsiyetleri arasında bulunan Ebû'l Feth Osman İbn Cinnî (ö. 392/1002) hayatını ilim ile geçirmiş, öğrenci yetiştirmiş ve çeşitli alanlarda kitaplar yazmıştır. İbn Cinnî öğrenci yetiştirmenin yanı sıra nahiv, sarf, lügat, edebiyat, Kur'ân ilimleri ve daha farklı konularda eserler kaleme almıştır. Yaşadığı dönemde sarf ve nahiv alanlarında yaptığı çalışmalar ile bu alanlarda öncü olmuştur. Nahiv alanında te'lif ettiği eserler arasında, veciz ve ihtilaflardan uzak, sade bir uslüpla kaleme aldığı el-Luma' eseridir. Bu eserinde nahiv konularını ihtiva etmesinin yanı sıra bazı sarf ve belagat konularına da yer verermiştir. Eserinde nahiv âlimleri arasında cereyan eden ihtilafları zikretmemiş, nahiv ekollerinin görüşlerini onlara nisbet etmeden zikretmiştir. Genel olarak Basri bir tutum sergilemiş olan İbn Cinnî konuları mezheb taasubundan uzak sade bir şekilde kaleme almıştır. Bununla birlikte kendi görüşlerine de zaman zaman yer vermiştir. Kitabın genelinde zikrettiği görüşü desteklemek amacıyla Kur'ân ve şiirlerden istişhâdlarda bulunmuştur. Bu çalışmada Osman İbn Cinnî'nin hayatı hakkında bilgiler verilmekte, nahiv alanında yazmış olduğu el-Luma' fi'l-Arabiyye adlı eser tanıtılmakta ve bu eserde istişhâd ettiği âyetler tespit edilerek, müellifin istişhâd vechi ile bu minvalde nahiv âlimlerinin görüşleri birlikte değerlendirilmektedir. Anahtar Kelimeler: Nahiv, İstişhâd, İbn Cinnî, el-Luma'Istishhād refers to citing examples from poetry and prose whose authenticity is certain in order to substantiate a rule or the meaning of a word existing in the Arabic language. The primary sources of istishhād are the Qur'an, hadith, poetry, and reliable Arabic discourse. Scholars of the Arabic language have considered istishhād using the Qur'an as the most appropriate method and emphasized that it is the most reliable source in terms of the Arabic language. In works authored in the fields of grammar (nahw), morphology (ṣarf), and lexicography, istishhād with Qur'anic verses has been frequently employed. Abū al-Fatḥ ʿUthmān Ibn Jinnī (d. 392/1002), who was raised in Mosul and counted among the distinguished figures of his era, devoted his life to knowledge, trained numerous students, and authored works in various fields. In addition to educating students, Ibn Jinnī produced writings on grammar (nahw), morphology (ṣarf), lexicography, literature, Qur'anic sciences, and other disciplines. His contributions in the fields of morphology and grammar during his lifetime made him a leading authority in these areas.Among his grammatical works is al-Lumaʿ, which he composed in a concise style, free from disputes, and in plain language. While the work primarily covers topics in grammar, it also addresses certain issues in morphology and rhetoric. Ibn Jinnī refrained from mentioning the disputes that arose among grammarians and avoided attributing the opinions of grammatical schools to their proponents. Generally adopting a Basran approach, he presented the subjects in a clear and unbiased manner, free from sectarian partisanship, while occasionally including his own opinions. Throughout the work, he supported his arguments by employing istishhād from the Qur'an and poetry. This study provides information about the life of ʿUthmān Ibn Jinnī, introduces his grammatical work al-Lumaʿ fī al-ʿArabiyyah, and identifies the Qur'anic verses he cited as istishhād. Furthermore, it evaluates the author's approach to istishhād alongside the views of grammarians in this regard. Keywords: Syntax (Nahw), Istishhad (Citation), Ibn Jinni, Al-Lum
Silage Quality and Economic Efficiency Analysis of Hungarian Vetch (Vicia Pannonica Crantz) and Oats (Avena Sativa L.) Mixed at Different Ratios
No full textBackground: In this study, it was aimed to compare Hungarian vetch and oats mixed at different ratios not only in terms of silage quality but also in terms of their economic efficiency. “Anadolu Pembesi” Hungarian vetch variety and “Albatros” oat variety were used as plant material in the experiment. Methods: Research was carried out during the winter of 2020-2021 on a farmer field in the Kızıltepe district of Mardin province (Turkiye). In the study, 100% Hungarian vetch, 100% oat, 70% Hungarian vetch + 30% oat, 60% Hungarian vetch + 40% oat, 50% Hungarian vetch + 50% oat, 30% Hungarian vetch + 70% oat silages were tested. Besides silage quality, input-cost analysis and comparison in terms of economic efficiency were also made in the study. Result: pH value, dry matter, crude protein ratio, acid detergent insoluble fiber, neutral detergent insoluble fiber, digestible dry matter, dry matter consumption, relative feed value and lactic acid ratio varied between 3.88-4.11; 25.02-29.24%; 12.17-19.64%; 31.34-40.24%; 45.27-55.14%; 57.55-64.49%; 2.18-2.65%; 97.15-132.58 and 1.82%-2.38%, respectively. When all the features are evaulated together, 70% Hungarian vetch + 30% oat silage mixture was recommended due to high crude protein ratio, high relative feed value and lactic acid ratio in between low acid detergent insoluble fiber and neutral detergent insoluble fiber ratios. On the other hand, 50% HVS + 50% OS and 60% HVS + 40% OS mixtures stand out as balanced options in terms of both economic gain and quality. This ratio represents the economic optimum point in roughage production and offers an important alternative in the creation of sustainable feed resources. © 2025, Agricultural Research Communication Centre. All rights reserved