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The Role of Self-Compassion in the Relationship of Posttraumatic Stress Disorder With Posttraumatic Growth in Kahramanmaraş Earthquakes Survivors: a Year on
No full textPosttraumatic stress disorder (PTSD) and posttraumatic growth (PTG) are two common posttraumatic reactions that may co-exist in individuals exposed to or witnessing an earthquake. There are a limited number of studies examining some mediating variables, such as self-efficacy and resilience in the relationship between PTSD and PTG in individuals exposed to traumatic experiences. However, these studies were not carried out with earthquake survivors, and self-compassion was not considered as a mediating variable. Therefore, in order to close this gap in the literature, the current study aims to reveal the mediating role of self-compassion in the relationship between PTSD and PTG in Kahramanmara & scedil; earthquakes survivors. The data of the study were collected from 317 survivors of the February 6 earthquakes in Turkey (78.2% females), aged 18 and 52 (Mean = 24.12 +/- 6.28). The results have indicated that PTSD was negatively correlated with self-compassion, whereas positively correlated with PTG. Self-compassion was found to be positively associated with PTG. More importantly, the findings have also revealed the mediating effect of self-compassion in the relationship between PTSD and PTG after controlling for gender, age, educational level, and marital status. The findings shed light on our understanding that self-compassion may not only play a protective role against the negative consequences of traumatic events, but also may be an effective mechanism in the transformation of PTSD into PTG. Moreover, the findings of the study have suggested that focusing on self-compassion may be functional for intervention programs aiming to prevent PTSD symptoms and increase PTG in earthquake victims.Inonu UniversityThe authors would like to thank all participants of the study
Evaluation of Thiol/Disulfide Homeostasis and Ischemia Modified Albumin as Potential Markers for Periodontitis
No full textBackground The current study aimed to assess the impact of periodontitis on oxidative stress parameters by examining serum total antioxidant capacity (TAS), total oxidant status (TOS), oxidative stress index (OSI), thiol/ disulfide homeostasis and ischemia modified albumin (IMA). Methods The study had 90 participants, categorized into 3 groups: Group 1: Periodontally healthy; Group 2: Stage II Grade B periodontitis; Group 3: Stage III and IV Grade B periodontitis. Demographic and periodontal variables were assessed. The levels of serum TAS, TOS, OSI, IMA, and thiol/disulfide were assessed. Results No significant differences in sex and age were detected among the groups (p > 0.05). When compared to Group 1, all clinical measurements were statistically significantly greater in Group 3 (p 0.05). The highest serum IMA value was observed in Group 3 (p = 0.037), whereas native thiol (p = 0.00), total thiol (p = 0.00) and disulfide values (p = 0.023) were highest in Group 1. Conclusions These findings indicate that thiol/disulfide homeostasis and IMA could hold promise as a potential biomarker of inflammation in periodontitis.ALKU BAPNot applicable
İlahiyat/İslami İlimler Arapça Lisans Programları: Mevcut Durum, İmkanlar ve Zorluklar
No full textBu araştırmada, İlahiyat/İslami İlimler (Arapça) lisans programları konu edilmiştir. Araştırmanın temel amacı, ilk örneği 2011 yılında açılmış olan söz konusu programların hangi fakültelerde yer aldığı, fakültelerin programlara yönelik amaçlarının ne olduğu, program müfredatlarının nasıl içeriklendirildiği, istihdam edilen öğretim üyeleri profili, programlara ayrılan öğrenci kontenjanları ve öğrenci alım şartları gibi hususları tespit etmek ve böylece İlahiyat/İslami İlimler (Arapça) lisans programlarının mevcut durumunu ve temel çerçevesini ortaya koymaktır. Doküman analizi yönteminin kullanıldığı bu araştırmanın bulgularından hareketle elde edilen sonuçlara göre; Arapça lisans programlarını barındıran on iki fakültenin bulunduğu ve bu fakültelerin, program aracılığıyla öğrencilerini İslam’ın temel kaynaklarına, ilmi ve kültürel mirasa, kadim geleneğe ve günümüz uluslararası konjonktüre hâkim birer mümin kişi olarak yetiştirmeyi amaçladığı anlaşılmaktadır. Ancak fakültelerin, amaçlarına ulaşmak için ortak bir müfredat geliştirmedikleri, mevcut müfredatlarda yer alan Arapça derslerinin oran ve içerik açısından farklı şekillerde yapılandırıldığı ve beş dil becerisini geliştirmeye yönelik yapılandırmayı yansıtmadığı anlaşılmaktadır. Arapça lisans programlarını barındıran fakültelerde, Türk akademisyenlerin yanında uluslararası öğretim elemanlarının da istihdam edildiği anlaşılmaktadır. Diğer yandan Arapça lisans programlarına ayrılan kontenjanların hemen her yıl dolduğu ancak öğrenci alımlarına yönelik herhangi bir özel şartın bulunmadığı anlaşılmaktadır. Bütün bu sonuçlar, araştırmada karşılaştırmalı ve eleştirel bir yaklaşımla yorumlanmış, böylece programların avantaj ve zorlukları tartışılmıştır
The Performance of the Naples Prognostic Score in Predicting One-Year Mortality and Major Adverse Cardiovascular Events After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis
No full textBackground: Existing risk scores for transcatheter aortic valve implantation (TAVI) may not fully capture patient complexity. Combining nutritional and inflammatory markers, the NPS (the NAPLES prognostic score) might improve outcome prediction. Aims: This study investigated the associations of the NPS with one-year mortality and major adverse cardiovascular events (MACEs) in TAVI patients. Material and methods:This retrospective analysis included 222 patients with severe aortic stenosis who underwent TAVI. The NPS was calculated based on the serum alb & uuml;min concentration, cholesterol concentration, lymphocyte/monocyte ratio, and neutrophil/lymphocyte ratio. The patients were subsequently categorized into two groups: the low-NPS group (NPS 0-2) and the high-NPS group (NPS 3-4). Results: A high NPS was significantly associated with increased one-year mortality (4.8% vs. 23.7%; P <0.001) and MACE rates (7.2% vs. 35.9%; P <0.001). Cox regression analysis demonstrated that a high NPS was an independent predictor of both mortality (HR, 5.94; 95% CI, 2.03-17.37; P = 0.001) and MACEs (HR, 5.09; 95% CI, 2.15-12.02; P <0.001). Conclusions: The NPS emerged as a potential predictor of long-term mortality and MACEs in TAVI patients. Further validation through larger, multicenter, studies is warranted.This research contributes valuable data on the role of the NPS in TAVI risk stratification
Fractional Approach for Diffusion Equations Arising From Oil Pollution Using the Fractional Natural Decomposition Method
No full textDusunceli, Faruk/0000-0002-2368-7963; Celik, Ercan/0000-0001-5971-7653The main goal is to use the fractional natural decomposition approach to solve diffusion equations related to oil pollution. We examine a model that depicts the evolution of chemical processes in a network that burns helium. Elegant consolidations of nature transform with Adomian decomposition method are made possible by the Caputo operator with fractional order taken into consideration and hired algorithm. We looked at the expected model in a different sequence using fraction to show the expected algorithm's proficiency. Moreover, plots for various arbitrary orders have taken use of the physical characteristics of the obtained results. The obtained findings verify that the algorithm under consideration is highly efficient, methodical, straightforward to use, and accurate in examining the characteristics of the fractional differential system connected to related fields
A Comparative Sociological Analysis of Women in the Thought of Rousseau and Wollstonecraft
No full textBu tez, Jean Jacques Rousseau ve Mary Wollstonecraft'ın kadına ilişkin görüşlerini karşılaştırarak sosyolojik bir analizini ortaya koymaktadır. Her iki düşünürün bu husustaki görüşleri genel olarak insan ve toplumsal roller çerçevesinde bütüncül bir anlamda ele alınmaktadır. Birinci Dalga (Liberal) Feminizmin kurucu teorisyenlerinden biri kabul edilen Wollstonecraft, iyi bir toplum inşa etmek için kadınların da erkekler kadar bireysel ve toplumsal sorumlulukları olduğunu belirtir. Rousseau'nun aksine kadınların bunları yapabilecek güç ve iradede olduklarını da vurgulayan Wollstonecraft hem gerçek hayatında hem de yazdığı birçok eserinde bu konuyu işlemiştir. Kendisi de bir Aydınlanmacı olan Wollstonecraft'ın, Aydınlanma karşıtlığıyla ünlü olan Rousseau'yu temel alarak yaptığı eleştiriler aslında Aydınlanmacıların kadınlara yönelik ihmalkâr tavırlarını da hedef almaktadır. Bununla birlikte tezde karşılaştırma için Rousseau tercih edilmiştir. Bunun temel sebebi, Wollstonecraft'ın kadının yeri, rolü ve doğasına yönelik söylemlerini akılsallık çerçevesinde ortaya koyarken Rousseau'nun kadını doğal olarak erkekten daha aşağı gördüğünü bilinçli bir şekilde belirtmesi ve bunu savunmasıdır. Bu temelde tez, Wollstonecraft'ın görüşlerini Rousseau'nun insan doğası, akıl, duygu, din, özgürlük ve toplumsal roller açısından kadına bakışı bağlamlarında ele alıp karşılaştırmaktadır. Bu bağlamda çalışmada nitel araştırma yöntemi kullanılmış, birincil kaynaklar olarak her iki düşünürün temel eserleri analiz edilerek teorik bir değerlendirme yapılmıştır. Böylece, Wollstonecraft'ın Rousseau'yu eleştrisi çerçevesinde kadın hakları ve toplumsal cinsiyet eşitliği konusundaki görüşleri sistemeatik bir biçimde incelenmiştir.This thesis presents a sociological analysis of Jean Jacques Rousseau and Mary Wollstonecraft by comparing their views on women. The views of both thinkers on this issue are generally considered in a holistic sense within the framework of human and social roles. Wollstonecraft, who is considered one of the founding theorists of First Wave (Liberal) Feminism, states that women have as much individual and social responsibilities as men in building a good society. Unlike Rousseau, Wollstonecraft emphasized that women have the power and will to do these things, both in her real life and in many of her works. The criticisms made by Wollstonecraft, herself an Enlightenmentist, based on Rousseau, who is famous for being anti-Enlightenment, actually target the Enlightenmentists' negligent attitudes towards women. However, Rousseau was preferred for comparison in the thesis. The main reason for this is that, while Wollstonecraft presents her discourses on the place, role and nature of women within the framework of rationality, Rousseau consciously states and defends that she sees women as naturally inferior to men. On this basis, the thesis discusses and compares Wollstonecraft's views in the context of Rousseau's view of women in terms of human nature, reason, emotion, religion, freedom and social roles
Evaluation of Extra Virgin Olive Oil Compounds Using Computational Methods: in Vitro, Admet, Dft, Molecular Docking and Human Gene Network Analysis Study
No full textONER, Erkan/0000-0002-6332-6484; UNSAL, VELID/0000-0003-1415-0563This study investigates the phenolic compounds (PC), volatile compounds (VC), and fatty acids (FA) of extra virgin olive oil (EVOO) derived from the Turkish olive variety "Sar & imath; Ulak", along with ADMET, DFT, molecular docking, and gene network analyses of significant molecules identified within the EVOO. Chromatographic methods (GC-FID, HPLC) were employed to characterize FA, PC, and VC profiles, while quality parameters, antioxidant activities (TAC, ABTS, DPPH) were assessed via spectrophotometry. The analysis revealed a complex composition of 40 volatile compounds, with estragole, 7-hydroxyheptene-1, and 3-methoxycinnamaldehyde as the primary components. Hydroxytyrosol, tyrosol, oleuropein, apigenin, ferulic acid, and vanillic acid emerged as main phenolic constituents, with hydroxytyrosol and apigenin exhibiting high bioavailability. Molecular docking highlighted oleuropein and pinoresinol as compounds with strong binding affinities, though only hydroxytyrosol, apigenin, and pinoresinol fully met Lipinski and other drug-likeness criteria. DFT analysis showed that oleuropein and pinoresinol have notable dipole moments, reflecting polar and asymmetrical structures. KEGG enrichment analysis further linked key molecules like oleuropein and apigenin with pathways related to lipid metabolism and atherosclerosis, underscoring their potential bioactivity and relevance in health-related applications
Innovation for Sustainability: the Role of Digital Circular Economy in Driving Organizational Efficiency and Sustainable Development
No full textThis paper explores the critical relationship between innovation and sustainability, emphasizing the role of the digital circular economy (DCE) in advancing sustainability goals. Sustainability, defined by its environmental, social, and economic dimensions, requires an integrated, interdisciplinary approach to address global challenges. Innovation serves as a key driver in this process, enabling businesses to adapt their models, processes, and products to meet sustainability objectives. By integrating sustainability into organizational strategies and governance frameworks, firms can enhance operational efficiency and long-term competitiveness while minimizing environmental impact. The paper highlights the importance of sustainable innovation governance, which aligns organizational goals with broader sustainability objectives through effective policies and practices. Additionally, it explores how digital technologies within the circular economy (CE) facilitate resource efficiency, reduce waste, and support closed-loop systems that contribute to sustainable development. This study addresses sustainability and innovation in terms of organizational processes, strategies, and business models, drawing on literature to assess their impact. The theoretical framework evaluates both past studies and the implications of adopting digital circular practices, offering insights and recommendations for future business sustainability initiatives. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025
Neoscytalidium Dimidiatum as a Postharvest Pathogen Affecting Solanaceous Vegetables
No full textNeoscytalidium dimidiatum, a member of the Botryosphaeriaceae family, is an emerging global plant pathogen. Although recently reported on various hosts in T & uuml;rkiye, its impact on commercially available vegetables remained undocumented. This study provides the first report of N. dimidiatum causing postharvest decay in the eggplant (Solanum melongena L.), pepper (Capsicum annuum), potato (Solanum tuberosum), and tomato (Solanum lycopersicum) obtained from local Turkish markets in 2023. The pathogen was identified through morphological characterisation and molecular analysis targeting the internal transcribed spacer (ITS) region, translation elongation factor 1-alpha (tef1), and beta-tubulin (tub2) gene sequences. The pathogenicity of N. dimidiatum was confirmed through Koch's postulates at 28 degrees C, and its temperature-dependent effects were assessed on solanaceous vegetables. Disease progression, measured by the area under the disease progress curve (AUDPC), was strongly influenced by temperature. No disease was observed at 12 degrees C. At 18 degrees C, limited disease development occurred in the eggplant and potato. AUDPC values increased significantly at 25 degrees C, generally peaking at 30 degrees C, with some hosts showing similar levels of disease severity at 35 degrees C. These findings highlight the critical role of postharvest temperature control, particularly rapid cooling and cold storage, in minimising losses caused by N. dimidiatum. This is the first report of N. dimidiatum as a postharvest pathogen affecting the eggplant, pepper, tomato fruits, and potato tubers, and the first record of this pathogen on the eggplant and pepper globally, expanding its known host range and reinforcing its significance as an emerging threat to global agriculture
Long-Term Impact of Self-Mobilization Via Telerehabilitation Vs. Manual Therapy and Home Exercise on Pain and Function in Cervical Degenerative Disease
No full textCelik, Erman Berk/0000-0001-6115-4669; Tuncer, Aysenur/0000-0002-5660-1134Purpose: Cervical Degenerative Disease (CDD) commonly leads to neck pain, functional impairment, and reduced quality of life. This study aimed to compare the long-term effects of home exercise, manual therapy, and telerehabilitation-assisted treatment on pain, functionality, and patient satisfaction in individuals with CDD. Patients and methods: Sixty-six patients diagnosed with CDD were randomly assigned to three groups: home exercise (n = 23), manual therapy (n = 22), and telerehabilitation (n = 21). All groups participated in an 8-week exercise program, with the manual therapy and telerehabilitation groups receiving additional sessions twice a week. Pain was measured using the Visual Analogue Scale (VAS), pain threshold with an algometer, neck function with the Neck Disability Index and range of motion (ROM), and patient satisfaction with the Patient Satisfaction Questionnaire-18. Results: All groups significantly improved pain, function, and ROM over time (p < 0.05). But there were no significant differences between groups at the 6-month follow-up. Manual therapy and telerehabilitation significantly enhanced patient satisfaction, particularly in communication and technical quality (p < 0.05). Conclusion: Home exercise, manual therapy, and telerehabilitation improve long-term outcomes in CDD. Manual therapy and telerehabilitation provide greater patient satisfaction, making them viable options for long-term management. Telerehabilitation can be used as an alternative when necessary