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    861 research outputs found

    Twenty-Year Course of Antifungal Resistance in Candida Albicans in Türkiye: A Systematic Review and Meta-Analysis

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    This study aimed to systematically evaluate the resistance rates of Candida albicans to various antifungals based on studies conducted in Turkiye and published between 2005 and 2025 and to analyze the factors contributing to resistance. A systematic literature search was conducted using various keywords in electronic databases (PubMed, Embase, Web of Science, EBSCO, Scopus, Turk Medline and Google Scholar). A total of 42 studies were included in the meta-analysis according to the determined criteria. The quality of the studies was assessed using the Joanna Briggs Institute checklist, and the analyses were performed using appropriate statistical software. The highest resistance rates for fluconazole, itraconazole, and voriconazole were observed in the Aegean and Marmara regions. In the analyses performed with the random-effects model, heterogeneity was found to be high for itraconazole, fluconazole, posaconazole, voriconazole, and caspofungin, and the strongest explanatory variable of this heterogeneity was the geographical region variable. In our study, we determined that antifungal resistance in C. albicans strains in Turkiye is generally low; however, an increasing trend has been observed over the years, especially in amphotericin B resistance. Although the low resistance rates to major antifungal agents such as fluconazole, voriconazole and echinocandins are promising, regional differences and methodological heterogeneity necessitate the development of treatment strategies based on local data.Science Citation Index Expande

    Evaluation of the Barriers to Maintenance 4.0 for the Textile Industry via Pythagorean Fuzzy SWARA

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    Maintenance 4.0 studies have become a focus for managers and employees when developing effective and efficient maintenance policies. In this study, the barriers to Maintenance 4.0 applications in the textile industry are investigated, and these barriers are weighted using the Stepwise Weight Assessment Ratio Analysis (SWARA) method based on Pythagorean fuzzy numbers. Solutions to address these barriers are presented. As a result of this study, Organizational and Managerial emerged as the most important main criterion. Operational was identified as the second most significant main criterion, followed by Technical Competence. Data-Related and Cybersecurity ranked fourth in terms of importance. On the other hand, Human Resources and Training and Financial were found to be the least important main criteria. These two criteria received lower importance scores compared to the others, with Financial being the criterion with the lowest overall significance. Sensitivity analyses were performed for six different scenarios by changing the importance weights of the decision-makers. The ranking of the criteria only slightly changed with the weights; this means that the results obtained in Case 1 are robust and reliable. Even in Case 6, where the expert weight ratios were completely reversed, the results did not change significantly. This highlights an important point regarding the reliability of the assessment.Science Citation Index Expande

    Analiza Poziomów Odporności Psychicznej Wśród Trenerów Judo W Zależności Od Wybranych Czynników Demograficznych

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    Background. Psychological resilience is a crucial personal trait that enables individuals, especially those in high-stress professions like coaching, to adapt and thrive in the face of adversity. Understanding how resilience manifests among coaches can contribute to more effective support and development strategies in sports psychology. Problem and aim. This study aims to determine whether the psychological resilience levels of judo coaches differ according to demographic variables such as age, educational background, coaching certification level, years of coaching experience, profession, and perceived economic status. Material and methods. The sample included 284 active judo coaches (58 women and 226 men) from Istanbul, Kutahya, and Eskisehir. Data were collected using the “Psychological Resilience Scale for Adults” [Friborg et al. 2003; Basim, Cetin 2011] and a “Personal Information Form.” Statistical analyses were conducted using SPSS 24.0, including independent samples t-tests, one-way ANOVA, and Eta squared analysis to assess the influence of demographic actors on resilience levels. Results. The findings indicated significant differences in psychological resilience levels based on gender, marital status, age, educational attainment, coaching experience, income level, and coaching certification level. Conclusions. The results suggest that psychological resilience among judo coaches is meaningfully influenced by various demographic characteristics. These findings underscore the importance of tailoring psychological support and development programs to the specific profiles of coaches. © Yoshin Academ

    STS: Yapay Zeka Destekli Akıllı Test Senaryosu Olusturma Aracı

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    One of the most critical steps in the software testing lifecycle, test scenario generation, reduces process efficiency due to its high time and resource requirements. As an innovative solution to this issue, the Smart Test Scenario Tool (STS) has been developed. Smart Test Scenario Tool (STS) enhances contextual accuracy and automation in test scenario generation by analyzing documents in xlsx, py, cpp, txt, and docx formats using large language models. This approach minimizes time loss, and the risk of errors encountered in traditional manual testing processes while transforming test procedures into a context-driven and systematic framework, offering an innovative contribution to the literature. Strengthened with a Streamlit interface, MongoDB-supported database management, and Ollama integration, the system enables the test scenario generation process, a critical component of the software testing cycle, to be conducted more efficiently and reliably. The validity of the study was confirmed through two distinct projects, the first implemented in Python and the second in C++

    Critical Spatial Reasoning in Designing: A Visitor’s Centre Relating to Beylikdüzü Archaeological Site, Istanbul

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    Architectural Design Studio helps students develop the skills to abstract, conceptualise and analyse space. This paper addresses the process of developing critical thinking and design, focusing on the central project, relating to Beylikdüzü Archaeological Excavation Site in Istanbul, Turkiye. This project provides the opportunity for students to explore the context, restrictions of the site and metaphors in design while operating more as an incubator for collaboration than a formal studio course. More specifically, the project aims to improve links between the welcome centre and the archaeological site and hence fills a research gap by exploring the value of producing three-dimensional thinking able to deliver architectural solutions that are new to the context. The purpose of the study is to investigate students' abilities in site analysis, topography and environment for appropriate designs that are functional and sustainable. Methods such as SWOT analysis and topographical studies are incorporated within the framework to propose a unified design solution that is sensitive to both the archaeological site and cultural attachment. The results show integrated and innovative solutions that combined the welcome centre with the archaeological area, helping to enrich the visitor experience. Cultural preservation and taking into consideration the value of archaeological sites to integrate them with minimum damage in new architectural interventions is another aspect seen through this project. © 2025 Elsevier B.V., All rights reserved

    Yetişkinliğe Geçiş ve Yerleşik Yetişkinlik: Psikolojik ve Sosyal Değişimler Üzerine Nitel Bir Araştırma

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    Beliren yetişkinlik ve orta yetişkinlikten farklı gelişimsel özellikleri ve yaşam olaylarını içermesi nedeni ile 30 ile 45 yaşları arasındaki gelişim dönemi yerleşik yetişkinlik olarak adlandırılmıştır. Bu araştırmada yetişkinliğe ilişkin algıların, yetişkinliğe geçiş deneyimlerinin, yerleşik yetişkinlikteki psikolojik ve sosyal değişimlerin incelenmesi amaçlanmıştır. Çalışmaya 30 ile 35 yaşları arasındaki 16 yerleşik yetişkin katılmıştır. Araştırma betimleyici fenomenolojik desende yürütülmüştür ve yarı-yapılandırılmış görüşmeler yapılarak veri toplanmıştır. Yapılan tematik analizde yetişkin algısı, yetişkinliğe geçişte rol oynayan etmenler, benlik, kimlik ve değişim, sosyal ilişkilerdeki değişim ve geleceğe ilişkin beklentiler olmak üzere beş ana tema oluşturulmuştur. Katılımcıların çoğunluğu kendilerini yetişkin olarak algıladıklarını ifade etmiştir. Yetişkinliğe geçişi; sorumluluk alma, özerklik ve ekonomik bağımsızlık kazanmaya dayalı olarak ele almışlardır. Araştırma yerleşik yetişkinlikte kendini anlamanın ve bilgeliğin arttığını, kimlik arayışının azaldığını ya da sonlandığı, önceliklerin, ebeveynler ve arkadaşlar ile ilişkilerin niteliğinin değiştiğini göstermiştir. Bazı katılımcıların yerleşik yetişkinlik döneminde yaşamdaki olasılıklarının azaldığını düşündükleri belirlenmiştir. Çalışma Türkiye’deki yerleşik yetişkinlerin deneyimlerinin daha iyi anlaşılmasına ve yerleşik yetişkinliğin ayırt edici özelliklerinin belirlenmesine katkıda bulunmaktadır

    Effects of Motor Imagery Adding To Physiotherapy and Rehabilitation Program in Children With Duchenne Muscular Dystrophy: Does It Make a Difference

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    Introduction/background: The study aims to investigate the effects of the MI (Motor Imagery) program applied in addition to the PTR (Physiotherapy and Rehabilitation) program on gait and balance in children with DMD (Duchenne Muscular Dystrophy). Methods: The 38 boys with DMD were included in the study and randomized into two groups: the PTR group (mean age: 7.96 +/- 1.94 years) and the MI + PTR group (mean age: 9.03 +/- 1.71 years). In the PTR group, the PTR program was administered 2 days/week for 8 weeks, and in the MI + PTR group, the MI program was administered 5 days/week in addition to the PTR program. Groups were assessed by the Brooke Lower Extremity Functional Classification Scale, Modified Pediatric Mini Mental Scale, Movement Imagery Questionnaire (MIQc), Kinovea (R) Software Program, Timed Up & Go Test (TUG), Timed Function Tests (TFT), Two-Minute Walk Test (2MWT), and Motor Function Measure (MFM-32). Results: As a result of the study, in PTR Group, TFT-Stairs descending (p = 0.049) was improved. In MI + PTR Group, Kinovea (R) Software Program-Walking Speed (p = 0.003), 2MWT (p = 0.037), TFT-Stair descend and 10-m walk (respectively; p = 0.001; p = 0.039), and MFM-32-D1 (p = 0.036) were improved. According to the comparison between groups, the groups were not superior to each other (p > 0.05). Discussion/conclusion: Although the MI program applied in addition to the PTR program contributes to improvements in walking speed, walking distance, and functional performance in children with DMD, it does not demonstrate superiority over the PTR program alone.Science Citation Index Expande

    The Psychometric Properties of Body-Related Self-Conscious Emotion Measures for Turkish Adolescents: Esem and Cfa Approaches

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    The aim of this study was to investigate the psychometric properties of the “Body and Appearance Self-Conscious Emotions Scale (BASES)” and “Body and Fitness-Related Self-Conscious Emotions Scale (BSE-FIT)” for Turkish adolescents. Each scale consists of 16 items and four subscales (shame, guilt, authentic pride, and hubristic pride) and items are responded on 5-point Likert scale. The psychometric properties of BASES and BSE-FIT were tested on 332 girls and 264 boys, a total of 596 participants (Mage=13.88, SDage=1.92). Confirmatory factor analysis (CFA) and exploratory structural equation modelling (ESEM) with multi-group analysis (MGA) were used to test the 4-factor and 2-factor structures and measurement invariance. Cronbach’s alpha internal consistency coefficient and composite reliability (CR) were calculated for reliability. According to the model fit indices and factor loadings, the most appropriate model was the 4-factor CFA model for BASES and BSE-FIT. Cronbach’s alpha and CR coefficients were 0.79 and above in the 4-factor CFA structures of both scales. In addition, MGA demonstrated factor structures, factor loadings, intercepts, and measurement error variance of BASES and BSE-FIT were equivalent according to sex, school level, sport status, region, and body mass index. In conclusion, BASES and BSE-FIT are valid and reliable in Turkish adolescents, and both scales provided measurement invariance in adolescents with different demographic characteristics. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.Social Science Citation Inde

    Cross-Cultural Adaptation, Validity, and Reliability of the Turkish Version of the Cumberland Ankle Instability Tool for Athletes

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    CONTEXT: To cross-cultural translate the Cumberland Ankle Instability Tool (CAIT) to Turkish version (CAIT-T) and to evaluate the validity, reliability, and cutoff score of CAIT-T for Turkish athletic population. DESIGN: The English version of CAIT was translated to CAIT-T based on a guideline of cross-cultural adaptation. Fifty-two athletes with chronic ankle instability and 63 athletes without chronic ankle instability were included in the study. Construct validity was evaluated with correlations between the CAIT-T, Turkish version of Foot Ankle Ability Measure (FAAM-T), and Numeric Rating Scale. CAIT-T was completed twice by each participant at 7 to 10 days intervals to assess test-retest reliability based on the intraclass correlation coefficient, whereas Cronbach alpha evaluated internal consistency. Discriminative validity and content validity of the CAIT-T also evaluated. RESULTS: In construct validity, strong positive correlation was found between CAIT-T and Numeric Rating Scale perceived ankle instability (rho = -.771, P < .001), as well as moderate negative correlations with FAAM-T-activities of daily living and FAAM-T-sports (rho = -.448, P < .001 and rho = -0.541, P < .001, respectively). The CAIT-T demonstrated strong test-retest reliability (intraclass correlation coefficient score of .98) with a good internal consistency (Cronbach α: .85). Receiver operating characteristic curve showed a cutoff score of 26.5 (Youden index: 0.78, sensitivity: 0.57, specificity: 0.90.5). No ceiling or floor effects were observed. CONCLUSIONS: CAIT-T is a valid and reliable questionnaire for the assessment of chronic ankle instability in the Turkish athletic population. This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicin

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