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Nurses' Views on Change Management in Health Care Settings: a Qualitative Study
No full textCelebi Cakiroglu, Oya/0000-0001-5552-4969Aim To discover nurses' views on change management processes in health care settings. Background Because 'change' is an inevitable fact of today's health care environments, developing change management competencies at all levels is a must to survive and compete for the organisations and professionals in the health care systems. Methods A descriptive qualitative approach was used. The sample consisted of 18 nurses reached by using snowball sampling. The data were collected through semi-structured interviews and analysed using the Colaizzi method in the NVivo12 program. Results The results of the study were collected under three main themes: 'general approaches and initial responses to change', 'factors affecting attitudes toward change' and 'strategic mistakes made by managers during the change process'. Conclusion The study showed that nurses show different reactions to change. Their attitudes towards change could be affected positively and negatively by the relevant factors. Nurses thought that managers were making strategic mistakes during the change process. Implications for nursing management Recognizing the approaches of nurses and managers towards change and increasing awareness of the mistakes during the change process may contribute to the achievement of the change processes in health care settings.Science Citation Index Expanded - Social Science Citation Inde
Morphological and Biochemical Investigation of the Healing Effects of Exercise on High Fat Diet Induced Kidney and Bladder Damage
Get PDFErcan, Feriha/0000-0003-2339-5669; Sener, Goksel/0000-0001-7444-6193; Bingol Ozakpinar, Ozlem/0000-0003-0287-5639; Kolgazi, Meltem/0000-0003-4820-1904Objective: The aim of this study was to evaluate the ameliorative effects of swimming training on renal and bladder damage caused by a highfat diet (HFD) using morphological and biochemical measurements. Methods: Sprague Dawley rats were fed either standard chow (CONT, 6% fat) or HFD (45% fat) for 18 weeks, these rats were divided into two subgroups at the last 6 weeks of the experiment. The exercise groups (CONT+EXC, HFD+EXC) were trained daily swimming sessions (1 h per day for 5 days/week) during the last 6 weeks. Kidney and bladder samples were prepared for light and electron microscopic examination at the end of experiment. Malondialdehyde, glutathione, interleukin-6, and tumor necrosis factor-a were measured by biochemically. Results: Regular morphology of the renal cortex and bladder mucosa was observed in the CONT and CONT +EXC groups. Degenerated renal corpuscles and proximal tubules in the kidney and degenerated urothelium with leaky tight junctions and mast cell increase in the bladder mucosa were observed in the HFD group. Ameliorated renal cortex and bladder mucosa were observed in the HFD+EXC group. In addition, malondialdehyde, glutathione, interleukin-6, and tumor necrosis factor-a levels were also consistent with the histological findings. Conclusion: HFD-induced renal and bladder damage may be related to increased oxidative damage. It was observed that the histological damage and altered oxidative stress parameters could be reversed by swimming training, and it is thought that moderate swimming exercise may play a role in regulating oxidative stress.Marmara University, Scientific Research Project Committee [SAG-B-110.117.0003]The authors would like to thank to the Marmara University School of Medicine students Sevde Arikan, Yesim Gezer, Yesim Ozbabalik and Alperen Akbaba for their support to the histological tissue processing. This study was financially supported by Marmara University, Scientific Research Project Committee (SAG-B-110.117.0003).Emerging Sources Citation Inde
Psychometrics of Stanford Presenteeism Scale-Short Form in Turkish
Get PDFAIM: Presenteeism means that employees feel obliged to go to work even if there is a real problem that they cannot work.The main purpose is to to adapt the "Stanford Presenteeism Scale-Short Form" into Turkish on Nurses. METHOD: This is a methodological study. The study sample included the nurses working at the medical and surgical clinics of two public hospitals in 2017 in Istanbul. A total of 290 nurses participated in the study. Language, content, construct validities, total item correlation analysis, Kaiser Meyer Olkin, Bartlett tests, confirmatory and explanatory factor analysis (EFA), stability, and Cronbach's alpha reliability analyses were tested. RESULTS: The content validity index of the scale was.92. Two items that have correlation values below.40 were removed from the Turkish form. Cronbach's alpha internal consistency coefficient was.762. The structure of the four-item and single-factor Turkish form was confirmed. CONCLUSION: Stanford Presenteeism Scale-Short Form is a valid and reliable tool for the nurses in Turkey. It is recommended to be used among nurses in different studies. Hospital and nursing care service managers should deal with "presenteeism," since it is becoming a critical health human resource workforce issue. Health care managers may use this tool to evaluate the presenteeism level of their employees.Research Fund of Istanbul University [23063]The present work was the master dissertation thesis which had been funded by the Research Fund of Istanbul University (Project No. 23063).Emerging Sources Citation Inde
Survival in Rhino-Orbito Mucormycosis: an International, Multicenter Id-Iri Study
No full textBackground: Mucormycosis is an emerging aggressive mold infection. This study aimed to assess the outcome of hospitalized adults with rhino-orbito-cerebral mucormycosis (ROCM). The secondary objective was to identify prognostic factors in this setting. Methods: This study was an international, retrospective, multicenter study. Patients’ data were collected from 29 referral centers in 6 countries. All qualified as “proven cases” according to the EORTC/MSGERC criteria. Results: We included 74 consecutive adult patients hospitalized with ROCM. Rhino-orbito-cerebral type infection was the most common presentation (n = 43; 58.1%) followed by rhino-orbital type (n = 31; 41.9%). Twenty (27%) had acquired nosocomial bacterial infections. A total of 59 (79.7%) patients (16 in combination) received appropriate antifungal treatment with high-doses of liposomal amphotericin B. Fifty-six patients (75.7%) underwent curative surgery. Thirty-five (47.3%) required intensive care unit admission (27; 36.5% under mechanical ventilation). Hospital survival was 56.8%, being reduced to 7.4% in patients with invasive mechanical ventilation. A multivariate binary backward logistic regression model identified confusion at admission (OR 11.48), overlapping hospital-acquired infection (OR 10.27), use of antifungal treatment before diagnosis (OR 10.20), no surgical debridement (OR 5.92), and the absence of prior sinusitis (OR 6.32) were independently associated with increased risk for death. Conclusion: Today, ROCM still has high mortality rate. Improving source control, rational therpy, and preventing nosocomial infections may improve survival in this severe infection. © 202
Bir Nefroloji Kliniğinde İstenen Psikiyatri Konsültasyonlarının Değerlendirilmesi
Get PDFAmaç: Bu çalışma, bir eğitim ve araştırma hastanesinin nefroloji\rkliniğinde yatarak tedavi edilen hastalara istenen psikiyatri\rkonsültasyonlarını incelemek amacıyla yapıldı.\rYöntem: Tanımlayıcı, retrospektif desende yapılan bu çalışmanın\rörneklemini bir eğitim ve araştırma hastanesinin nefroloji kliniğinde\rOcak 2016-Eylül 2019 tarihleri arasında yatarak takip edilen ve\rpsikiyatri konsültasyonu istenen 64 hasta oluşturdu. Hastaların dosya\rkayıtları incelenerek, hastalığa ve psikiyatri konsültasyonlarına\rilişkin özellikler değerlendirildi.\rBulgular: Konsültasyon istenen 64 hastanın %60.9’unun erkek;\rhastaların yaş ortalamasının 54.65±15.63 olduğu saptandı. Hastaların\r%47.7’sinin kronik böbrek ve %46.7’sinin akut böbrek hastalığı\rtanıları ile yatarak takip edildiği, %23.4’ünde retinopati ek tanısının\rbulunduğu belirlendi. Araştırmaya dahil edilen hastaların,\r%40.6’sına ajitasyon ve %28.1’ine depresif belirtiler ön tanısı ile\rkonsültasyon istendiği belirlenirken; hastaların konsültasyon sonrası\r%38.9’una uyum bozukluğu ve %22.2’sine duygudurum bozukluğu\rtanıları konulduğu saptandı. Konsültasyon sonrası hastaların\r%39.1’ine antipsikotik ilaç reçete edildiği saptandı. Hastaların\rpsikiyatri başvuru sayısıyla kreatinin ve potasyum değerleri arasında\rnegatif ve orta dereceli anlamlı bir ilişki bulunurken, konsültasyon\ristem sayısıyla FT4 değeri arasında ise negatif ve zayıf anlamlı ilişki\rsaptandı (p<0.05).\rSonuç: Bu çalışmada taranan hastaların çok küçük bir örneklemine\rpsikiyatri konsültasyonu istendiği belirlendi. Böbrek hastalıkları olan\rbireylerde biyopsikososyal süreçlerde belirgin problemler\ryaşanmasına bağlı olarak hastaların bütüncül değerlendirilmesi ve\rtedavi ekibi ile iş birliği içinde bakımının sağlanması önemlidir.\rHastaların nefroloji kliniğine kabulünden itibaren ruhsal\rdeğerlendirmelerinin yapılmasının yanı sıra gerektiğinde ruh sağlığı\rçalışanlarından konsültasyon istenmesi oldukça önemlidir
İkna Bilgi Modeli Bağlamında Üstbilişin Reklamdan Kaçınma Üzerindeki Etkisi
Get PDFİkna Bilgi Modeli’ne göre reklam gibi ikna edici araçlara yönelik, tüketiciler zamanla bilgi toplamaktadır. Tüketici tarafından toplanan bu bilgiler tüketicinin ikna edici mesajlara yönelik olan düşüncelerinin yanı sıra, tüketicinin zihninde kendi ikna edilme durumları hakkındaki düşünceleri de kapsamaktadır. Kişinin ikna girişimlerinin yanı sıra kendi ikna durumları hakkındaki düşüncelerini ifade eden ikna bilgisi kavramı, literatürde üstbiliş olarak adlandırılmaktadır. İkna bilgisinin, üstbilişsel olarak kullanımının sonucunda kişiler ikna edici araçlara yakınlaştıkları gibi bu araçlardan kaçınma eğiliminde de bulunabilmektedir. Bu çalışmanın problemi kişilerin ikna bilgisi kullanımları doğrultusunda üstbilişin internet reklamlarından kaçınmaları üzerindeki düzenleme etkisini bulmaktır. Çalışmanın amacı, üstbiliş fonksiyonlarından biri olan üstbilişsel düzenlemenin, ikna bilgi modeli doğrultusunda internet reklamlarından kaçınma üzerindeki etkisini incelemektir. Bu doğrultuda üstbilişsel düzenleme faktörleri olarak düzenleme odaklılığı, hedef uyumluluğu, ikna bilgisi özyeterliği değişkenleri ele alınmış ve ikna bilgisi erişilebilirliği ile birlikte incelenmiştir. Çalışmanın amacı doğrultusunda iki farklı tam faktöriyel gruplararası deney yapılmış ve bu deneyler 18-45 yaş arasında Bahçeşehir Üniversitesi’nde 2021 yılında eğitimlerine devam etmekte olan lisans ve lisansüstü öğrenciler üzerinde gerçekleştirilmiştir. Yapılan deneylerden elde edilen verileri test etmek için İki Yönlü ANCOVA analizi kullanılmıştır. Deneyler sonucunda düzenleme odaklılığı, ikna bilgisi erişilebilirliği, hedef uyumluluğu bağımsız değişkenlerinin, kişilerin ikna bilgisi öz-yeterlikleri doğrultusunda internet reklamlarından kaçınma üzerinde ana faktör etkilerinin bulunmadığı; ancak düzenleme odaklılığı ile ikna bilgi erişilebilirliği, düzenleme odaklılığı ile hedef uyumluluğu değişkenlerinin internet reklamlarından kaçınma üzerinde etkileşim etkilerinin olduğu sonucuna ulaşılmıştır
Comparison of Intraoperative Biliary Anastomosis Stenting Technique in Living-Donor Liver Transplantation: Review of 41 Patients
No full textBackground/aim: Biliary fistula is one of the most important complications in liver transplantation. Complications can vary from simple local peritonitis to death, and various techniques have been described to prevent them. In this study, we compared two different stenting methods used in biliary tract anastomosis in living-donor liver transplantation. Material and methods: We retrospectively analyzed data from 41 living-donor liver transplantations that were performed due to end-stage liver failure between August 2019 and November 2020. Patients were grouped according to the stenting technique used in biliary anastomosis. Postoperative biliary tract complications were investigated. Results: Biliary fistulas were observed in 2 (7.4%) patients in the internal stent group, while 4 (28.5) fistulas were observed in the external stent group. Biliary tract stricture was observed in 2 (7.4%) patients in the internal stent group, but there was no statistical difference in complications. The preoperative MELD score (p = 0.038*) was found to be statistically significant in regard to developing complications. Conclusion: Our study did not show the effect of stenting methods used during biliary anastomosis on the development of complications. However, larger randomized controlled studies are needed. © TÜBİTAK
Pandemi Dönemi İş Güvenliği Algısı Ölçeğinin Geçerlik ve Güvenirlik Çalışması
No full textTüm ülkelerde çalışanların sağlık ve güvenliğini sağlamak, küresel ölçekte işletmeler için önemli bir sorun alanı olarak tüm varlığını sürdürmektedir. Nitekim 2019 Aralık ayından beri devam eden ve çalışma koşullarının değişmesine yol açan COVID-19 pandemisi de çalışanların sağlık ve güvenliğinin korunmasını önemli hale getirmiştir. Bu çalışmanın amacı, pandemi dönemi iş güvenliği algısı ölçeğinin geçerlik ve güvenirlik çalışmasının yapılmasıdır. Araştırmaya 681 çalışan katılmıştır. Araştırma verilerinin analizinde SPSS 22 ve LISREL 8.71 programları kullanılmıştır. Yapılan analiz sonucunda, ölçekte bulunan maddelerin faktör yüklerinin 0,778 ile 0,908 arasında değiştiği ve açıklanan toplam varyansın %84,14 olduğu görülmüştür. Yapılan doğrulayıcı faktör analizi sonuçlarına göre ölçek; (Ki-kare/sd: 4,72; RMSEA: 0.074; NFI: 0.99; NNFI: 0.99; CFI: 0.99; GFI: 0.96 ve AGFI: 0.93) 10 madde ve 2 faktörden oluşmaktadır. Ölçeğin içsel tutarlığı 0,956 olarak hesaplanmış ve madde-toplam korelasyonlarının 0,675 ile 0,879 arasında değiştiği tespit edilmiştir. Elde edilen bulgular, pandemi dönemi iş güvenliği algısı ölçeğinin geçerli ve güvenilir bir ölçüm aracı olduğunu göstermektedir
Thioethers: an Overview
No full textHan, Muhammed Ihsan/0000-0001-5610-0869Spreading rapidly in recent years, cancer has become one of the causes of the highest mortality rates after cardiovascular diseases. The reason for cancer development is still not clearly understood despite enormous research activities in this area. Scientists are now working on the biology of cancer, especially on the root cause of cancer development. The aim is to treat the cancer disease and thus cure the patients. The continuing efforts for the development of novel molecules as potential anti-cancer agents are essential for this purpose. The main aim of this review was to present a survey on the medicinal chemistry of thioethers and provide practical data on their cytotoxicities against various cancer cell lines. The research articles published between 2001-2020 were consulted to prepare this review article; however, patent literature has not been included. The thioether-containing heterocyclic compounds may emerge as a new class of potent and effective anti-cancer agents in the future.Science Citation Index Expande
Effects of Triphasic Training Model Combined With Two Different Cluster Sets on Vertical Jump and Reactive Strength Index
No full textKAYA, SELMAN/0000-0002-2185-6436Background and Study Aim This study aims to examine the effects of the Triphasic Training Model (TTM) applied with different set designs (15-30 sec intra-set) on reactive strength index (RSI) and vertical jump values. Material and Methods Sixteen male athletes over 18 with at least three years of strength training experience (2 days a week) actively engaged in sports participated in the study. The study group was divided into two groups by calculating the relative strengths. The 15-second cluster set (C15) group exercises were performed with 15 seconds of rest between repetitions, and the 30-second cluster-set (C30) group practiced the exercises with 30 seconds of rest between repetitions. The triphasic training model was applied to all study groups for six weeks. Countermovement jump (CMJ) and drop jump tests were performed on the athletes before and after the training. Optojump brand photocell system was used for CMJ and RSI tests. For the RSI test, the desk height was determined as 40cm. Kolmogorov-Smirnov values were examined to assess the homogeneity of the data. To compare the means between groups, ANOVA was used for Repeated Measures, and a t-test was used to compare the pretest-posttest mean of the groups. The statistical significance level was determined as p<0.05. Results After triphasic training, CMJ and RSI values of both C15 and C30 groups increased (p<0.05). When the within-group pretest-posttest values were examined, it was seen that the C30 group showed more improvement than the C15 group. Conclusions As a result, it was seen that the triphasic training model applied twice a week for six weeks improved the CMJ and RSI values of the athletes, and it was more effective to use C30 instead of C15 in the use of cluster sets.Emerging Sources Citation Inde