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From archival historiography to 3D modelling: An accurate reconstruction of the Palaeolithic landscape in El Castillo Cave to explore the spatial dynamics of hand stencil dispersion
No full textInternational audienceWe propose a comprehensive approach for the reconstruction of the prehistoric state of El Castillo Cave (Puente Viesgo, Cantabria) that allows a precise spatial analysis of the distribution of its parietal motifs.The cave has undergone numerous changes over time due to both geological and anthropic processes, which have altered its original appearance. In the aim of understanding how Palaeolithic societies used the space for creating rock art, we combined the study of historical archival data of different types with modern scanning and 3D modelling techniques. We began carrying out field data recollection, as well as archival research, including historical photographs, maps, excavation records and written and oral sources, supplemented by geomorphological analyses to assess natural and anthropic alterations of the cavity. In a second phase, using a 3D modelling software, we developed a three-dimensional model where we virtually removed modern modifications (e.g., staircases and lighting) and restored ancient soil levels, to reconstruct the cave as it likely appeared during the Upper Palaeolithic period. This work served as a basis for spatial analyses of the hand stencil motifs through Geographic Information Systems. This approach provides promising results in terms of interpretation of different types of space by suggesting they are a motif particularly easily accessible for a large viewership, therefore bringing us closer to the apprehension of prehistoric human behaviour and symbolic practices
Negative priors and inferences from absence of evidence in cognitive and linguistic archaeology: Epistemically sound and scientifically strategic
No full textInternational audienceStibbard-Hawkes (2025) provides an important warning but its general conclusions should be nuanced: (i) When there is no evidence for it, we should depart from the hypothesis that a species lacks a particular cognitive capacity, and (ii) inferences from absence of evidence can be epistemically sound and scientifically strategic in cognitive and linguistic archaeology
Introduction et présidence de la table ronde "Le contexte institutionnel européen de l'infra-étatisme"
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Les concepts d’interculturalité et de migration peuvent-ils faire partie du "tour du monde" des concepts ? Questionnement épistémologique
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Chaperone-mediated autophagy regulates appetite by fine-tuning hypothalamic amino acid pools: new insights from fish
No full textInternational audienceChaperone-Mediated Autophagy (CMA) is a key lysosomal proteolytic pathway essential for cellular homeostasis and metabolism, with dysfunction linked to various human diseases. While extensively studied in humans and mice, CMA was only recently identified in fish, paving the way for novel and evolutionary research perspectives. Here, we demonstrate for the first time a role for CMA in regulating feed intake (FI) in rainbow trout (Oncorhynchus mykiss), a major aquaculture species and a widely used model in numerous research fields, including physiology, evolutionary genetics, toxicology, immunology, and nutrition. Specifically, we first observed that starvation induces an increase in the CMA activation score – a reliable proxy for CMA activity – in the hypothalamus, a central brain region involved in the regulation of feeding behavior. To probe its functional relevance, we administered an intracerebroventricular (ICV) injection of the CMA activator CA77.1 and found a significant reduction in FI, suggesting a regulatory role for CMA in appetite. Further analysis indicated that CMA may influence FI, at least in part, by modulating hypothalamic free amino acid availability through ribosomal protein degradation. Through this mechanism, CMA may contribute to the precise regulation of satiety and represent a promising target for therapeutic strategies aimed at treating metabolic disorders and obesity, as well as for nutritional interventions to improve feed efficiency and promote more sustainable growth practices in aquaculture
Measurement of salt diffusion coefficient as a function of concentration in a free-diffusion cell by interferometry
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Diffusion Layer Convection of two superimposed brines: experimental and theoretical approaches
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De la complexité de la gouvernance locale de l’agroécologie : une constellation d’instruments, de champs d’action, d’acteurs et d’échelles
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