OHSU Digital Collections (Oregon Health and Science University)
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    Assessing receptivity to contingency management for methamphetamine use disorder in primary care

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    Methamphetamine use disorder (MUD) is a growing problem with few effective pharmacologic treatments. Though off-label medications used for MUD have only modest benefit, behavioral health treatment modality contingency management is effective in promoting abstinence and increasing treatment retention. Despite its documented effectiveness, CM is rarely used in practice due to legal, logistical, and implementation barriers. While primary care providers are increasingly comfortable with medications for opioid use disorder, they are less comfortable treating stimulant use disorder citing limited clinical experience, knowledge, and uncertain treatment options. This quality improvement project, conducted at an urban Federally Qualified Health Center (FQHC) in Portland, Oregon, aims to assess provider and staff receptivity to CM for MUD at baseline and after an educational in-service on CM to understand readiness for CM program implementation

    Quantifying the single-cell spatial landscape of cancer

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    This dissertation quantitatively assesses the single-cell spatial landscape of the tumor microenvironment for three cancer types. Statistical and machine learning approaches were used to identify candidate biomarkers of various clinical parameters, which can be leveraged to improve treatment strategies for future cancer patients. Importantly, the computational methods used here are widely applicable regardless of tissue type, and they provide a framework for future quantitative assessments of biological datasets resulting from any multiplex tissue imaging assay

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    Improving continuity of care in a rural health system: utilizing a transitional care tool

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    This quality improvement project sought to improve continuity of care for mentally ill patients who receive services from a rural mental health care system. A literature review found that poor communication, especially during transitions, impedes continuity of care and leads to negative outcomes. Interprofessional collaboration in the form of communication and information exchange is integral to successful transitions and continuity of care. Improving discharge processes and utilizing tools that facilitate discharge can improve communication practices. This paper details the steps taken to improve the discharge process, including the development of a transitional care tool, in this rural mental health care system

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